Migraine
LDL receptor gene polymorphism linked to migraine without aura
Published in Drug Week, September 26th, 2003
"We performed a genetic association study with the LDL receptor gene (LDLR) on chromosome 19p 13.2 in 360 migraine patients, 220 with migraine without aura (MO) and 140 with migraine with aura (MA), and 200 controls, by analyzing two polymorphic markers, a G142A transition in exon 10 and a triallelic (TA)n repeat in exon 18," scientists writing in the Journal of the Neurological Sciences report.
"The allelic distribution of the (TA)n polymorphism was significantly different between migraine without aura (MO) and both controls and...
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Source: Drug Week (2003-09-26)
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