Colon Cancer
Poloxamer-containing liposomes can be used for heat-sensitive drug delivery
Published in Drug Week, October 10th, 2003
According to published research from the United States, "A heat-sensitive liposomal drug delivery system was tested using Colon-26 (CT-26) cultured cells and tumors in mice.
"Lucifer yellow iodoacetamide (LY) was used as a fluorescence marker. The heat-sensitive liposomes exploit the temperature-dependence of critical micellar concentrations of the poloxamer, F127. LY release from unilamellar liposomes at different temperatures was measured," wrote J. Wells and colleagues, Roswell Park Cancer Institute, Molecular & Cellular Biophysics Department.
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Source: Drug Week (2003-10-10)
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