Drug Development
Ubiquitin-like peptide with anticancer and immunostimulatory activity isolated from mushroom
Published in Drug Week, October 10th, 2003
In a recent study from China, "A peptide, with a molecular mass of 9.5 kDa and demonstrating an N-terminal sequence similar to ubiquitin, was isolated from fruiting bodies of the mushroom Agrocybe cylindracea."
The isolation was performed using "a purification protocol involving ion exchange chromatography on DEAE-cellulose, affinity chromatography on Affi-gel blue gel, FPLC-ion exchange chromatography on Mono S and FPLC-gel filtration on Superdex 75," explained P.H.K. Ngai and coauthors at the Chinese University of Hong Kong.
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Source: Drug Week (2003-10-10)
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