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Thrombosis

Pediatric lupus patients with anticoagulants have variable risk for thrombosis

Published in Drug Week, October 17th, 2003

Thrombotic children with lupus anticoagulant and ACAs have the same risk as adults; however, those with no symptoms but the anticoagulants present are unlikely to develop complications.

"Lupus anticoagulant and ACAs are made up of heterogeneous IgG and IgM antibodies that prolong in vitro clotting times and are associated with increased risks of venous and arterial thrombosis, recurrent fetal loss, and autoimmune thrombocytopenia and anemia. These clinical findings with the appropriate laboratory results make up the antiphospholipid antibody syndrome," researchers in the United States report.

"The antiphospholipid antibodies found in this syndrome...

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