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Imaging

Ultrasound-guided liposomes boost imaging, target drug/gene therapy

Published in Drug Week, February 13th, 2004

One of the newest tools in the diagnosis and treatment of cardiovascular disease and stroke combines a 40-year-old imaging technique and liposomes, little globules of soluble fats and water that circulate naturally throughout the bloodstream.

The technique, developed by Northwestern University researcher David D. McPherson, MD, and colleagues with a $2.3 million grant from the U.S. National Institutes of Health, uses ultrasound energy to create microbubbles inside specially treated liposomes and then direct the liposomes to specific targets, such as atherosclerotic plaques or blood clots, in the coronary arteries and other arteries in the body, including those to the...

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