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Substance Abuse

Disulfiram, cognitive behavioral therapy appear effective for cocaine dependence

Published in Drug Week, March 26th, 2004

Disulfiram (a drug used to help selected patients with alcohol disorders remain sober) and cognitive behavioral therapy appear effective in reducing cocaine use, especially among cocaine users who are not dependent on alcohol, according to a new report.

Patients taking disulfiram who ingest even small amounts of alcohol develop a reaction that produces nausea, flushing, vomiting and throbbing headache. At times, this reaction can be severe and can lead to critical illness, such as severe respiratory problems, circulatory problems or even death. According to the article, alcohol is a powerful "cue" for using cocaine, and can impair judgment and lower resistance to...

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