Vaccine Development
New vaccine eliminates IL-6 immune response
Published in Drug Week, March 26th, 2004
According to published research from Denmark, "Inappropriate expression of IL-6 plays a role in various inflammatory conditions, degenerative diseases, and cancers. Several model systems have been developed that can specifically block IL-6-receptor interactions. Here we present a simple and highly effective approach based on vaccination with a pool of specifically mutated IL-6 analogues to induce a neutralizing IL-6 antibody response in mice."
"Judged by the ability of the analogues to bind to heterologous anti-IL-6 antibodies and cellular IL-6 receptors, the IL-6 analogues seemed to have a...
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Source: Drug Week (2004-03-26)
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