Drug Discovery

Challenges of virtual screening for kinase targets demystified

Published in Drug Week, May 14th, 2004

Challenges of virtual screening for kinase targets are demystified.

"Kinases have become a major area of drug discovery and structure-based design. Hundreds of 3D structures for more than thirty different kinases are available to the public. High structural and sequence homology within the kinase gene family makes the remaining kinases ideal targets for homology modeling and virtual screening," wrote researchers in the journal Current Medicinal Chemistry.

"Somewhat surprisingly, however, the number of publications about virtual screening of kinases is very low. Therefore, rather than reviewing the field of virtual screening for kinases",...

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Source: Drug Week (2004-05-14)

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