Virology

Mechanisms and biomedical applications of virus entry reviewed

Published in Drug Week, June 11th, 2004

Information about the molecular mechanisms governing virus entry may lead to novel biomedical applications.

"Viruses have evolved to enter cells from all three domains of life - bacteria, archaea, and eukaryotes. Of more than 3,600 known viruses, hundreds can infect human cells and most of those are associated with disease. To gain access to the cell interior, animal viruses attach to host-cell receptors," a scientist in the United States reports.

"Advances in our understanding of how viral entry proteins interact with their host-cell receptors and undergo conformational changes that lead to entry offer unprecedented opportunities for the development...

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Source: Drug Week (2004-06-11)

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