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AIDS

Scientists discover how AIDS opens cell doors

Published in Drug Week, June 11th, 2004

Researchers at the Salk Institute have discovered a way to view viruses like HIV upon cell entry.

Published in the May 18 edition of the Proceedings of the National Academy of Sciences, this research provides new insight into the chemical events that allow viruses like HIV to replicate within cells. When the virus enters a host cell, according to the study, its RNA genomes are converted to DNA, which integrates into the DNA of the host cell.

The study used a chicken virus modified to carry HIV, and reveals the steps taken by the retrovirus between entry (merging with the surface layers of the target cell) and protein expression (hitching onto...

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