Susan Hasty, Publisher
Table of Contents . . . June 25th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Asthma - Clinical trial to evaluate Xolair in pediatric allergic asthma patients
Breast Cancer - Chemotherapy including epirubicin may improve survival for some patients
Non-Hodgkin Lymphoma - FDA accepts Onco TCS new drug application
Pneumonia - FDA approves Avelox (moxifloxacin HCI) for community-acquired pneumonia
AIDS Vaccine - Volunteers needed as more AIDS vaccines move into clinical trials
Adverse Drug Effects - Lupus-like syndrome linked to simvastin therapy
Allergies - Full enrollment reported in phase II/III AIC trial
Allergy & Immunology - PAR-2-mediated activation enhances airway inflammation
Allergy Medicine - Dermatophagoides atopy patch tests are highly reproducible
Allergy Medicine - Allergy to ovalbumin induces lymphocyte migration to intestinal mucosa
Allergy Medicine - PAF responsiveness in subjects with plasma PAF acetylhydrolase deficiency
Allergy Medicine - Test methods evolving for newly emerging allergy epidemics
Alzheimer Disease - Beta-secretase modulates processing of APLP2 in vivo
Alzheimer Disease - Carboxyl-terminus of amyloid protein precursor needed to activate MAPK
Alzheimer Disease - Deactivation of two genes could be the cause of AD
Alzheimer Disease - Diffusion tensor imaging detects white matter changes in mouse model
Alzheimer Disease - Hypoxia remodels Ca2+ homeostasis in type I cortical astrocytes
Anemia - Successful cord blood stem cell transplant reported
Anesthesia - Cox-2 inhibitors reduce complications after laparoscopic surgery
Angiology - Endovascular management effective for iliac vein occlusive disease
Angiology - Nitric oxide and GABA mediate adrenomedullin's hypotensive effects in brain
Angiology - Study of decellularized carotid artery vascular grafts released
Angiology - TAL-1 stimulates endothelial cell migration and morphogenesis
Anorexia - Megestrol acetate improves appetite and weight gain in cancer and AIDS patients
Anti-Infectives - Polycomplexes of poly(acrylic acid) and streptomycin sulfate characterized
Antibacterial Research - NMR evidence found for independent domain structures in zoocin A
Antibiotics - Antibiotic activity of field-collected Streptomycetes characterized
Antibiotics - Biopharmaceutical company announces additions to fungicide patent portfolio
Antibiotics - FDA approves amoxicillin and clavulanate potassium for oral suspension
Antidepressants - Serotonin increases neurotrophic factor release in glioblastoma cells
Antimicrobials - Structural motif of alpha-helical antimicrobial peptides identified
Apoptosis - Caspase-mediated cleavage of syntaxin 5 and giantin occurs in apoptosis
Apoptosis - Granzyme B encoded by RAH allele retains pro-apoptotic activity
Apoptosis - TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis
Aspergillus - Method for purification of Aspergillus niger xylanase developed
Aspergillus - Production of melanin by Aspergillus fumigatus reviewed
Assisted Reproduction - Low-dose luteinizing hormone boosts ovulation but mitigates hyperstimulation
Asthma - Alvesco (ciclesonide) has no effect on HPA-axis function
Asthma - FDA approves ANDA for Terbutaline Sulfate Injection
Asthma - Gene at root of urban air pollution's lung effects
Asthma - Xopenex improves FEV1 more than racemic albuterol in study patients
Atherosclerosis - PAD patients should be aggressively treated for atherosclerotic risk factors
Atherosclerosis - Vulnerable atherosclerotic plaque identified with novel texaphyrin compounds
Atherosclerotic Disease - Vitamin E in dialysis fluid may reduce endothelial damage
Autoimmune Disease - ELISA for detection of autoantibodies to BP230 developed
Autoimmune Disease - Mice made to express liver cell osteopontin model human autoimmune hepatitis
Avian Influenza - Biotech firm to make flu vaccine for U.S. National Institutes of Health studies
Avian Influenza - NIAID announces contracts to develop vaccine against H5N1 strain of bird flu
Awards - 2004 Analytical Instrumentation Company of the Year named by Frost & Sullivan
Bacterial Meningitis - Choroid plexus involved in host defense
Bacteriology - Histopathologic changes in kidney and liver correlate with SPE B production
Bardet-Biedl Syndrome - Oligogenic properties of Bardet-Biedl syndrome reviewed
Benign Prostatic Hyperplasia - FDA warning letter clarified by biotech firm
Bioengineering - 2'-O-methyl- groups stabilize the binding of phosphorothioate antisense ODNs
Bioengineering - Cell matrix-modified implants stimulate new vessel growth in animals
Biomarker Discovery - Advanced multiplexed protein labeling technology described
Biotechnology - Glassy carbon microchip developed for electrospray mass spectrometry
Bladder Cancer - Carbonic anhydrase IX predictive of outcome in bladder cancer
Blood Banking - Autologous FG by CryoSeal FS System suggestive for hypothetical blood saving
Blood Screening - Consensus determines principles of screening and prevention of vCJD
Blood Vessel Formation - Phase I trial of ATN-224 initiated in patients with solid tumors
Brain Cancer - Bispecific immunotoxin effective in murine model
Brain Cancer - Microspheres developed for 5-FU delivery to brain
Brain Cancer - RNAi delivery system crosses blood-brain barrier to target brain tumors
Breast Cancer - Adding Herceptin to chemotherapy regimen boosts response rates in early disease
Breast Cancer - Aromasin after Tamoxifen lessens breast cancer recurrence in study
Breast Cancer - Concordance between HER-2 testing methods determined
Breast Cancer - Drug shrinks tumors or slows growth in up to half of women
Breast Cancer - Epirubicin and paclitaxel activity independent of adjuvant therapy
Breast Cancer - FDA grants approval for Gemzar in combination with Taxol
Breast Cancer - Gemcitabine/paclitaxel combination extends patients' overall survival
Breast Cancer - Gene expression ratio identifies recurrence risk in patients receiving tamoxifen
Breast Cancer - Gene mutation, use of certain antidepressants may decrease tamoxifen's effects
Breast Cancer - Overview of neoadjuvant endocrine therapy for breast cancer published
Breast Cancer - RT-PCR for mammaglobin genes detects sentinel lymph nodes micrometastases
Breast Cancer - Tamoxifen stimulates tumor growth following alteration of estrogen receptor
Breast Cancer Survival and Mortality - CD105 identifies node-negative breast cancer patients with poor prognoses
Breast Cancer Therapy - Radiation and subsequent TRAIL/Apo-2L quells breast tumor xenografts in mice
Breast Cancer Vaccine - Electroporated DNA vaccine clears breast cancer in transgenic mice
Business & Finance - Biopharmaceutical company achieves second milestone of license agreement
Business & Finance - Biopharmaceutical company announces participation in NASDAQ Biotechnology Index
Business & Finance - Biopharmaceutical company reports loss of $0.02 per share
Business & Finance - Biotechnology company receives first success-based milestone payment
Business Update - Collaboration to develop various dosage forms of cephalosporin antibiotics
Business Update - Drug developer to realign product development strategy
Business Update - Genetic manufacturing company relocates
Business Update - Pharmaceutical company announces new name and ticker symbol
Business Update - Portfolio of OTC and personal care brands acquired from Pfizer
Business Update - Pozen shares plummet after migraine drug rejected
Business Update - U.K. pharmaceutical company to establish U.S. headquarters in Pennsylvania
Cancer - Life sciences research and information company launches new publication
Cancer - Ligand-based VTA technology presented at international conference
Cancer - Phase II clinical studies to study Pivanex in leukemia and melanoma
Cancer - Scope of breast duct to be distributed in the Middle East
Cancer Cell Biology - Researchers pinpoint unlikely ally in cancer fight
Cancer Diagnosis - Immunomagnetic separation depicts esophageal cancer micrometastasis
Cancer Diagnostics - S100C staining may aid diagnosis of thyroid lesions
Cancer Prognosis - High levels of serum VEGF predict poor outcomes after liver cancer therapy
Cancer Recurrence - The management of recurrent cancer after prostatectomy is not clear cut
Cancer Research - CEACAM6 crosslinking leads to increased extracellular matrix component adhesion
Cancer Screening - Prostatic adenocarcinomas can be detected in men with low PSA values
Cancer Therapy - Algal toxin may disrupt the tumor fighting functions of E-cadherin
Cancer Therapy - Amifostine does not protect lungs from carmustine-containing chemotherapy
Cancer Therapy - Cannabis may help nausea, pain, and spasticity
Cancer Therapy - Electrochemotherapy may be a new treatment for solid tumors
Cancer Therapy - Genetically engineered virus targets "selfish" cancer cells
Cancer Therapy - Marine sponge Homaxinella sp. yields new cytotoxic metabolites
Cancer Therapy - Radiotherapy toxicity linked to abnormal transcriptional responses to DNA damage
Cancer Therapy - Scientists block cellular enzyme activity involved in cancer progression
Cancer Therapy - The thalidomide analogue CC-5013 uses T-cell induction to fight cancer
Cancer Vaccine - Melanoma cells expressing CD83 induce antitumor immunity
Cancer Vaccine - NY-ESO-1 protein protects against NY-ESO-1+ tumors
Cancer Vaccine - Researchers turn tumor cells in situ into tumor epitope-presenters
Candida Vaccine - Candida albicans strain protects against systemic candidiasis
Carcinogens - Exposure route dictates lung cancer type after arsenic contact
Carcinogens - New animal models show the carcinogenic synergy of UV radiation and arsenic
Cardiology - 30-day safety data available for coronary stent
Cardiology - Cardiology imaging and information company to manage stent trial
Cardiology - Cigarette smoking predicts reduced maximal FEV1 level in males but not females
Cardiology - Heparin coating protects blood during open-heart procedures
Cardiology - Intrinsic implantable cardioverter-defibrillator now available in Europe
Cardiology - L-type calcium channel subunit expression clarified in developing heart
Cardiology - Medtronic launches InSync cardiac resynchronization therapy system in Japan
Cardiology - New clinical data on stent performance announced
Cardiology - New report shows diagnostics driving cardiovascular market
Cardiology - Potential treatment for aortic aneurysm repair surgery given FDA fast track status
Cardiology - Recreation of published results may confirm nanobacteria in arteries and valves
Cardiology - Technology company invests in catheter-based technology for heart valve repair
Cardiovascular Disease - Heat-inactivated C. pneumoniae is not atherogenic
Cardiovascular Disease - Impaired apoptotic cell clearance enhances atherogenesis and autoimmune disease
Cardiovascular Disease - Metabolic syndrome positively associated with cardiovascular disease
Cardiovascular Disease - Moderate hepatic impairment has limited effect on azimilide pharmacokinetics
Cell Biology - Nck and Crk adaptor proteins modulate VEGF-controlled cell migration
Cervical Cancer - HPV oncoproteins expressed by foreskin cells alter the angiogenic environment
Childhood Obesity - After school activities can reduce obesity among inner city youth
Chirality - Method to determine chirality determination of amino acids developed
Chlamydia - Glycosaminoglycans protect against Chlamydia infection in vitro
Cholesterol - Cholesterol regulates GCase activity/stability in Niemann-Pick disease type C
Chronic Bronchitis - Avelox promotes rapid remission of chronic bronchitis symptoms in study
Chronic Constipation - Zelnorm demonstrates safety and efficacy in chronic constipation studies
Chronic Hepatitis C - Diligence is important for managing patients with hepatitis C virus infections
Chronic Lymphocytic Leukemia - Rituximab called most promising emerging drug for chronic lymphocytic leukemia
Chronic Myeloid Leukemia - A few questions remain concerning chronic myeloid leukemia
Chronic Obstructive Pulmonary Disease - Tiotropium Bromide Inhalation Powder recommended for COPD in ATS guidelines
Cochlear Implant - Effects of pulse rate on Clarion cochlear implant performance determined
Cochlear Implants - Cochlea is surgically accessible through middle cranial fossa
Cognition - Cognitive performance varies after radiation therapy for brain tumors
Collaborations - Exclusivity rights to 150mg generic Zyban relinquished
Collaborations - FTC clears reacquisition of intranasal influenza vaccine products
Collaborations - Licensing agreement signed to develop, market Lumigan in Japan
Collaborations - Option granted for rights to blood platelet modification technology
Collaborations - Pandemic influenza vaccine agreement signed
Collaborations - Pharmaceutical firm gets $21M award under expanded agreement
Collaborations - Rights acquired to retinoid portfolio
Colon Cancer - Multiple local IL-2 treatments effective in mice
Colon Cancer - Nitric oxide rules colon carcinoma angiogenesis markers differentially
Colorectal Cancer - Bio-pathological profile is prognostic in colorectal adenocarcinomas
Colorectal Cancer - Expression of p185 protein has prognostic value
Colorectal Cancer - Flavaglines induce apoptosis in colorectal cancer cells
Colorectal Cancer - Oral PSK with UFT reduced recurrence in colorectal cancer
Colorectal Cancer - Treatment options for liver metastases from colorectal cancer outlined
Complementary & Alternative Medicine - Licorice extract significantly improves learning and memory
Compliance - Many don't get full dose of chemo
Congestive Heart Failure - Data published on study of blood volume measurement
Constipation - Constipation treatment has no rebound effect after discontinuation
Coronary Artery Bypass Surgery - Intraoperative metoprolol does not improve beta-adrenergic receptor function
Coronary Artery Disease - ABT-578-eluting stents may inhibit restenosis
Coronary Artery Disease - Carvedilol may reverse MDR1/P-glycoprotein-mediated multidrug resistance
Coronary Blockage - Diabetic patients benefit from Cypher Sirolimus-eluting coronary stent
Critical Care Medicine - Factors predictive of postextubation stridor identified
Critical Care Medicine - Radiologic-assisted endotracheal intubation described
Crohn Disease - Antegren to be submitted for approval in Europe
Cutaneous Melanoma - Altering the limb perfusion schedule of cutaneous melanoma does not alter response
Cystic Fibrosis - Patent application filed for potential cystic fibrosis treatment
DNA Research - 53BP1 links DNA damage response to Ig heavy chain class-switch recombination
DNA Vaccine - Inoculation of plasmid DNA induced expression of LacZ gene
Dengue Fever - IgG avidity test can distinguish primary from secondary dengue infections
Dermatology - Nephrogenic fibrosing dermopathy characterized
Detection - RAPD analysis useful for genotyping clinical Candida spp. isolates
Diabetes Pathogenesis - B cell selection defects promote diabetogenic antigen-presenting cells
Diabetes Pathogenesis - Bovine serum albumin in cow's milk not likely cause of diabetes
Diabetes Pathogenesis - Cytokine disruption shared by macrophages from diabetic and lupus mice
Diabetes Pathogenesis - IL-10-resistant PGS2 expression found in type 1 diabetic monocytes
Diabetes Pathogenesis - Increased islet antigen presentation leads to type1 1 diabetes
Diabetes Pathogenesis - Prior 5-HT exposure on rat islet insulin responses investigated
Diabetes Research - New DNA technology used by tissue-banking firm to study diabetes
Diabetes Therapy - Fraxinus excelsior and Silybum marianum are hypoglycemic
Diabetes Therapy - Syzigium cumini seeds are antidiabetic and antihyperlipidemic
Diabetes Therapy - Diabetes in older adults reviewed
Diabetes Therapy - K+ stimulates proinsulin biosynthesis in rat pancreatic islets
Diabetes Therapy - Language used in relation to diabetes may undermine therapy efforts
Diabetic Nephropathy - Rapid change in glucose level aids mesangial cell proliferation
Diagnostic Imaging - PET may become invaluable for diagnosing and treating brain tumors
Diagnostics - Adaptive mechanical index can shorten color blooming in Doppler flow imaging
Diagnostics - Agreement adds positron emission tomography to medical center's imaging menu
Diagnostics - Automated schistocyte counting method evaluated
Diagnostics - FDA requests and approves new name for infection imaging product
Diagnostics - In vivo bioluminescence imaging reveals tumor elements in animal models
Diagnostics - Method to minimize interference of silver staining with MS developed
Diagnostics - Molecular assay detects RSV, influenza, and parainfluenza viruses
Diagnostics - New ClinProt products launched for proteomics, biomarker discovery
Diagnostics - Radioiodinated MMP inhibitor tracers may enhance tumor imaging
Diet and Nutrition - Arabinogalactan offers no long-term benefits on serum lipids or glucose
Diet and Nutrition - Dietary proteins in regulation of food intake and body weight reviewed
Diet and Nutrition - S-adeno-syl-L-methionine in dietary supplements characterized
Diet and Nutrition - n-3 Fatty acid supplements raise exercise levels in pancreatic cancer patients
Disease Diagnostics - New agreement will help develop diagnostic tests in oncology and other diseases
Drug Access - New campaign against reimportation launched
Drug Advertising - FDA warning letter issued on promotional materials for Advate
Drug Approval - New survey highlights FDA's successes and failures
Drug Delivery - Behavior of drug-loaded "microballoons" in stomach characterized
Drug Delivery - Biodegradable thermoplastic depot maintains camptothecin stability
Drug Delivery - Chitosan membrane shows promise for transdermal dosing
Drug Delivery - Crystallization of NEA in transdermal patch characterized
Drug Delivery - Gel-entrapped tamoxifen offers sustained drug release at tumor sites
Drug Delivery - New drug delivery system allows for combination of drugs
Drug Delivery - Optimal conditions determined for impinging jet-based drug dispersal
Drug Delivery - PLGA microspheres suitable for ocular peptide delivery
Drug Delivery - Scientists smuggle drugs into tumors
Drug Delivery - Transdermal Delta8 -THC system developed
Drug Development - Advances in understanding autism may lead towards effective treatment
Drug Development - Chitosan microspheres potential carrier for drugs
Drug Development - Class-action suit filed over brain cancer drug
Drug Development - Collaboration to develop pegylated formulation of Zadaxin
Drug Development - Conditionally replicating adenoviruses with short hairpin RNAs silence genes
Drug Development - Endotoxin testing not needed for inhalation grade lactose
Drug Development - Han fangji extract inhibits granulocyte activity in rheumatoid arthritis
Drug Development - Hepatitis C virus NS3 protease inhibitors need select elements for efficacy
Drug Development - Isoflavone metabolite inhibits ERK-1 activity in vascular smooth muscle cells
Drug Resistance - Different mechanisms produce VX-950 and BILN 2061 resistance
Drug Resistance - Short-term morphine exposure doesn't subdue multidrug resistance
Drug Resistance - Topoisomerase II alpha foils the effectiveness of etoposide in myeloma cells
Drug Resistance - c-Jun NH2 -terminal kinase opposes prostate cancer apoptosis
Drug Safety - Study will use bioinformatics to examine genetic causes of adverse drug reactions
Endocrinology - Androgens work through prohibitin to steer prostate cancer growth
Endocrinology - Breast cancer cell CD36 expression ebbs in response to estradiol
Endocrinology - Human glucose transporter-like protein-9 characterized
Endocrinology - Intestinal secretion regulation involving neurotransmitters reviewed
Endocrinology - Metabolic products measured by NMR analysis of one glucose derivative
Endocrinology - Noradrenaline and neuropeptide Y from hypothalamus high in diabetes
Endocrinology - Researchers design potent retinoid X receptor alpha agonists
Endometrial Cancer - Recurrent disease with a molecular alteration may respond to targeted therapy
Endometriosis - Mouse model developed as tool for drug testing, gene target validation
Environmental Health - Immunologic effects of perinatal PCB, dioxin exposure persist into school age
Environmental Health - Insulin-like growth factor 1 increased in people exposed to pollutants
Enzymology - ELISA methods for enzymes in cancer tissues developed
Enzymology - Evans Blue acts as protein tyrosine phosphatase inhibitor
Enzymology - High-throughput screening detects heat-shock protein 90 ATPase inhibitors
Enzymology - Seprase encourages tumor and microvessel growth in breast cancer models
Epilepsy - Distribution agreement announced for epilepsy treatments
Expression Analysis - Mouse genome microarray launched
Fatty Liver Disease - Nonalcoholic steatohepatitis histologically resembles alcoholic liver disease
Fertility - Positive phase II data reported on Cetrorelix
Fibrosis - Syndecan-2 regulates transforming growth factor-beta signaling
Finance - Biopharmaceutical company announces pricing of IPO
Finance - Biopharmaceutical company announces subsidiary's bridge debt financing
Finance - Biotech company announces pricing of initial public offering
Finance - Biotech company complete $4 million funding arrangement
Finance - Biotech company delisted by Nasdaq
Finance - Biotechnology company approved for American Stock Exchange listing
Finance - Diagnostic products firm announces $1M private placement
Finance - Information management company reports first quarter results
Finance - Japanese company receives $600,000 investment from two Far East distributors
Finance - Life sciences company delists from Berlin stock exchange
Finance - Medical device company announces fourth quarter results
Finance - Medical information company in danger of NASDAQ de-listing
Finance - NASDAQ biotechnology index adds new company
Finance - New biotech public offering
Finance - Ophthalmology company announces secondary offering
Finance - Pharmaceutical company completes first phase of investor conferences
Finance - Pharmaceutical firm announces $25M underwritten stock offering
Finance - Pharmaceutical firm raises $51M in series C financing
Finance - Pharmaceuticals announces initial public offering
Finance - Pharmacy benefit and health care company announces annual results
Finance - Psychiatric drug maker reports loss of $0.36 per share
Gastric Cancer - Results of phase II study of G17DT vaccine reported
Gastroenteritis - Efficacy results announced for gastroenteritis-causing rotavirus vaccine
Gastroenteritis - Licensing agreement will further research into norovirus treatments
Gastroenteritis - New license agreement for norovirus detection technology
Gastroenterology - ABCG2 may be involved in the evolution of colon cancer drug resistance
Gastroenterology - Etodolac staunches colitis-induced tumors in rodent models
Gastroenterology - Promising therapies available for the treatment of Crohn disease
Gastrointestinal Disease - FDA approves gastrointestinal selective antibiotic
Gene Delivery - Novel imaging assesses non-viral transfer systems
Gene Induction - Inducible promoters aid gene expression in head and neck cancer cells
Gene Silencing - Epigenetics may offer new approach to aging, cancer
Gene Transfer - 2-Amine is major bystander metabolite when CB 1954 is activated by NTR in tumors
Gene Transfer - High-capacity hybrid viral vectors garner transduction stability
Genetic Engineering - Stem cell factor gene-modified natural killer cells overwhelm tumor cells
Genomics - FBI awards contract for DNA analysis
Genomics - Gene encoding C. stercorarium beta-xylosidase Xyl43B in E. coli sequenced
Genomics - Genetic differences in ethnic groups affect the chronicity of hepatitis C
Genomics - Loss of heterozygosity on chromosome 12 concurs with lung cancer induction
Genomics and Genetics - ChromoViz software graphically maps genomic data onto chromosomes
Genomics and Genetics - Estrogen-related genes identified in murine uterus
Geriatrics - Amide molecular clocks in Drosophila proteins may regulate aging
Ginkgo Biloba - Ginkgo biloba protects liver against diabetes and hypoxia damage
Graves Ophthalmopathy - Role of cytokines in pathogenesis elucidated
Gynecology - Polycystic ovary follicular excess may be main culprit for follicular arrest
HIV Diagnosis - HIV-1/2 oral fluid rapid tests under development
HIV/AIDS - (+)-Inophyllum B and (+)-calanolide A candidates for anti-HIV therapy
HIV/AIDS - AIDS-related NHL is treated traditionally as supportive care improves
HIV/AIDS - Ezrin/CD95 linkage key role regulating susceptibility to CD95-mediated apoptosis
HIV/AIDS - New protease inhibitors offer improved clinical effectiveness
HIV/AIDS - Pharmaceutical company launches second wave of Global Health Fellows Program
HIV/AIDS Gene Therapy - TAT-pK/DNA complex useful way to package therapeutic genes for cell transduction
HIV/AIDS Progression - Timed ablation of regulatory CD4+ T cells prevents AIDS progression
HIV/AIDS Research - Central domain of HIV-1 matrix protein influences virus infectivity
HIV/AIDS Research - Channels formed by Vpu result from the self-assembly of monomers
HIV/AIDS Research - FIV env-mediated fusion mechanism and kinetics are similar to HIV env
HIV/AIDS Treatment - Cell surface targets identified for HIV-1 therapeutics using genetic screens
HIV/AIDS Treatment - New protease inhibitors offer improved tolerability and safety
Haemophilus Vaccine - Haemophilus influenzae meningitis in immunodeficient girl reported
Head & Neck Cancer - Docetaxel is active against squamous cell carcinoma of the head and neck
Head and Neck Cancer - The loss of RASSF1A expression propels nasopharyngeal cancer proliferation
Health and Fitness - Multiple myeloma patients commit to exercise based on a number of factors
Healthcare Access - "VA-style' prescription drug benefit won't work in Medicare, pharmacy group says
Healthcare Access - Significant increases in co-payments may reduce patients' use of needed drugs
Healthcare Coverage - Midwest bank and patient assistance program to offer loans for hospital bills
Heart Disease - Data demonstrate cardiovascular impact of weight loss with sibutramine
Heart Disease - Enrollment in Taxus registry completed
Heart Disease - Positive results presented from PISCES stent trial
Heart Failure - AbioCor replacement heart implanted in 14th patient
Hematology - Bfl-1/A1 is a potent antiapoptotic stimulant in myeloma cells
Hematology - Cryoprecipitate-removed plasma is factor IX source for treatment of hemophilia B
Hematology - Updated results presented from phase III study of Dacogen in MDS
Hepatitis - Hepatitis A virus cDNA-transfected Ltk-cells might reveal viral pathogenesis
Hepatitis - Hepatitis C virus NS3 and NS4A interactions modulate RNA unwinding activity
Hepatitis - New Phase II trial slated for chronic hepatitis C
Hepatitis A Vaccine - Immunogenicity data on Aventis Pasteur hepatitis A vaccines compiled
Hepatitis B Vaccine - Mechanism of hepatitis antigen adsorption by Al(OH)3 elucidated
Hepatitis C - African Americans respond poorly to hepatitis C treatment
Hepatitis C - Oral prodrug selected for front-line treatment of chronic hepatitis C
Hepatitis C Therapy - Hepatitis C patient study to measure A4+L liver product QOL results
Hepatitis C Therapy - Phase I/II trial to study R803 for the treatment of hepatitis C
Hepatitis C Therapy - Trial studies merimepodib in hepatitis C non-responders to peg-IFN and ribavirin
Hepatitis C Virus - Hepatitis C virus E2 glycoprotein mutations examined
Hepatocellular Carcinoma - Molecular markers evolve early in hepatitis B virus-related liver cancer
Hepatology - The transcription factors Snail and SIP1 heighten liver cancer invasion
Hereditary Angioedema - DX-88 placed on clinical hold pending review
Herpesvirus - HHV-8 vFLIP essential for survival of infected lymphoma cells
Hip Replacement - Bone cement reduces acetabular cup wear
Hormone Replacement Therapy - Estradiol-chemical delivery systems considered
Hormone Replacement Therapy - Options other than CEE and MPA are available
Human Antibodies - Lymphoma treatments receive EU orphan drug designation
Human Genome - Genomics company publishes DNA sequence of human chromosome 10
Hypercholesterolemia - Thrombocyte activity is marker of LDL-apheresis intensity
Hypertension - Alagebrium demonstrates benefits on heart, kidney in preclinical studies
Hypertension - Ambrisentan phase II results presented at ATS 2004
Hypertension - Blood pressure drugs cut death rate in half
Imaging - Nanoparticles illuminate brain tumors for days under MRI
Immune Mediated Diseases - Clinical trial of new immunomodulatory agent set to begin
Immunology - $100,000 invested in software modeling systems for inflammatory diseases
Immunology - A single class II myosin modulates T-cell motility
Immunology - Angiotensin II receptors modulate murine macrophage activity and phagocytosis
Immunology - Anti-inflammatory activity of retinoids elucidated
Immunology - CD11b levels predict risk of pollution-induced airway inflammation
Immunology - Crystal structures of IL-2 tyrosine kinase characterized
Immunology - E2A protein regulates marginal zone B-cell development
Immunology - Effects of glucocorticoids on renal epithelial cells clarified
Immunology - HIV infection impairs immunity to malaria in pregnant women
Immunology - Influence of phosphoinositide 3-kinase on T-cell activity reviewed
Immunology - Interleukin receptor kinase deficiency linked to bacterial infections
Immunology - Modified interferon-beta protein may one day help multiple sclerosis patients
Immunology - New phase I cancer trial planned
Immunology - Novel polymorphism in cytoplasmic region of IgA Fc receptor gene found
Immunology - Protection against infection may depend upon healthy host-microbe interactions
Immunology - RIP1 plays key role in TLR3-induced NF-kappaB activation
Immunology - S1P receptor activation by FcepsilonRI trigger required for mast cell function
Immunology - Selected peptides functionally represent the Fc-gammaRII-binding part of IgG1
Immunology - Serum factor I mediates C3b cleavage on S. aureus surface
Immunology - Stable immunological synapse not needed for efficient T-cell killing
Immunology - Structural basis for ICAM-1 dimerization elucidated
Immunology - TOX plays calcineurin-dependent role in CD8 cell lineage commitment
Immunology - Toll-like receptor signaling regulates phagosome maturation
Immunology - Triad3A regulates Toll-like receptor signaling
Immunology - Ubi-L suppresses cAMP-induced p38 MAPK activation in Th2 cells
Infectious Disease - Additional results from Europe available for TB test; kits shipped to China
Infectious Disease - Modes of hantavirus transmission inferred from mitochondrial DNA analyses
Infectious Disease - Multiplex PCR effective for Salmonella typing
Infectious Disease - Treatment of long-term catheter-related Brevibacterium described
Influenza - Positive progress reported on powder vaccine delivery technology
Influenza Vaccine - Influenza viruses isolated in 1997 and 2003 have antigenic differences
Information Technology - New tool released to improved protein identification
Kidney Cancer - Bispecific antibody works against micrometastatic renal cell carcinoma
Kidney Failure - Zemplar (Paricalcitol Injection) receives FDA approval for pediatric use
Kidney Transplantation - Immunosuppressants may hasten oncogenesis in patients with p53 mutations
Kidney Transplantation - Immunosuppression without calcineurin inhibitors safe, effective
Kidney Transplantation - Tacrolimus-associated myositis reported in renal graft recipient
Kidney Transplantation - Two-hour postdose levels optimal for pediatric cyclosporine monitoring
Knee Replacement - CT-guided knee replacement system improves accuracy
Laser Technology - Distribution agreement reached for laser system treatment for enlarged prostate
Legal Issues - Pharmaceutical company to seek rehearing of court ruling in diet drug trials
Legal Issues - Taxol settlement brings Coloradans $430
Legal Issues - Tennessee cancer patients get $265,000 in Taxol settlement
Legionnaire Disease - FDA grants 510(k) clearance for Legionella pneumophila test
Legislation - Pharmaceutical company reports higher revenue, earnings
Leptin Studies - Features of leptin-induced hypertension described
Leptin Studies - Leptin and membrane fluidity of erythrocytes in hypertension studied
Leukemia Therapy - Effective rituximab treatment of B-cell PLL reported
Leukemia Therapy - High CD33-antigen levels limit gemtuzumab efficacy
Lipid Studies - Lipoprotein profiles under varied androgen blockade conditions reported
Lipid Studies - New class of lipid absorption inhibitor from sage discovered
Lipogenesis - IL-1 and LPS downregulate PPAR-gamma in brown adipocytes
Lipogenesis - Liver X receptors stimulate adipocyte differentiation via PPAR-gamma
Lipogenesis - Notch target gene plays dual roles in differentiation of preadipocytes
Liposuction - Hemodynamics and organ histology of large-volume liposuction reported
Liver Cancer - Novel PCR-array system useful for gene expression profiling
Liver Cancer - Utility of cryotherapy as ablative treatment evaluated
Liver Cancer Therapy - Quadruple therapy battles liver cancer on several fronts
Liver Disease - Nonalcoholic fatty liver disease encompass benign steatosis and steatohepatitis
Liver Failure - Treatment options vary for acute liver failure
Liver Metastasis - Epirubicin levels in liver metastases after administration reported
Lung Cancer - Enrollment completed in pivotal trial of Xyotax
Lung Cancer - Lung screening test may prove useful as first line of lung cancer testing
Lung Cancer - Matrix metalloproteinase-2 encourages pulmonary adenocarcinoma invasion
Lung Cancer - Variations in DNA repair genes may predict survival in lung cancer patients
Lyme Disease - B. burgdorferi saliva inhibits neutrophil activity
Lymphoma - Contract research organization to help develop monoclonal antibody for lymphoma
Lymphoma - FDA issues special protocol assessment for phase III trial of FavId
Malaria - MS analysis of P. falciparum protein variants reported
Malaria - Proteomics in malaria reviewed
Malaria Vaccine - Merozoite surface protein antibodies inhibit malaria antibody responses
Managed Care - New research shows Miami as most competitive HMO market
Management - Biopharmaceutical company names new board chair
Management - Generic pharmaceuticals developer appoints new board member
Management - New board member announced
Management - Tennessee pharmaceuticals company expands into New Jersey
Mangement - Biopharmaceutical company names new board director
Market Analysis - Drug price increases in 2003 nearly triple
Measles Outbreak - Largest U.S. outbreak of measles in 1999 characterized
Measles Outbreaks - Measles outbreak control in adult populations discussed
Measles Risk Factor - Risk of measles transmission low after exposure on airline flight
Measles Vaccine - Clinical significance of measles reviewed
Measles Vaccine - Evolution of measles elimination strategies in the United States
Measles Vaccine - Progress toward measles eradication in the Americas updated
Medical Devices - Aortic Starr-Edwards ball valve prosthesis replaced after 28 years
Medical Devices - Femoral nerve catheter knotting reported
Medical Devices - Immunoassay for detection of irradiated prawns developed
Medical Devices - TIPS stent-grafts do not prevent liver transplantation
Medicare - Prescription drug discount cards show significant, sustained discounts
Medicare - Unclassified, FDA-approved drugs administered to outpatients will be reimbursed
Medicare Reform - Beneficiaries with chronic conditions still face high costs under new drug law
Medicare Reform - New study identifies leading Medicare reform factors
Medication Compliance - Many patients diagnosed with chronic illness stop taking medicines
Melanoma - MART1/MelanA stains have high false-positive rate
Melanoma Vaccine - Melanoma vaccine based on vector of membrane fusogenic liposomes
Melanoma Vaccine - Reproductive death delayed in progeny of irradiated melanoma cells
Meningococcal Vaccine - Integrity assay for meningococcal type B conjugate vaccine developed
Menopause - Bio-identical hormone replacement therapy is alternative treatment for menopause
Mental Health - 5-HT2C receptors contribute to actions of central serotonin systems
Mental Health - Federal program focuses mental health program in state of Florida
Mental Health - Publication highlights link between antidepressants and increased risk of suicide
Mergers & Acquisitions - Acquisition of Novocure completed
Mergers & Acquisitions - Agreement signed to acquire Chinese state-owned pharmaceutical firm
Mergers & Acquisitions - Business information provider Medtech Insight acquired
Mergers & Acquisitions - Ophthalmic device firm commences offer to acquire Drew Scientific Group
Mergers & Acquisitions - Renal Care Group acquires dialysis programs in Iowa
Metabolism - Scientists discover way to regulate the body's energy expenditure
Metapneumovirus - Human metapneumovirus recovered from cDNA
Metastases - Researchers identify a novel target for cancer therapy
Metastasis - Antisense oligonucleotides diminish breast cancer cell migration
Metastasis - Breast metastases from extramammary malignancies are rare
Metastasis - Vitamin E succinate abates human prostate cancer cell invasiveness
Metastatic Solid Tumors - Patient treatment begins in Reolysin trial for metastatic solid tumors
Microbial Testing - FDA approves ues of microbiological test as part of drug quality control process
Microfluidics - New technology introduced to replace liquid chromatography columns
Molecular Diagnostics - Molecular typing techniques are useful for detecting pathogenic fungi
Mucosal Immunization - Intestinal villous cells allow antigen entry site in mucosal epithelium
Multiple Sclerosis - Effects of glatiramer acetate on blood-brain barrier inflammation clarified
Multiple Sclerosis - Fibrin augments neuroinflammatory demyelination
Multiple Sclerosis - Leptin modulates inflammation in relapsed patients
Mutagenesis - PTEN gene alterations don't appear to impact synovial sarcoma prognosis
Myelodysplastic Syndromes - FDA approves Vidaza (azacitidine for injectable suspension) for MDS
Myocardial Infarction - Calcium antagonists are effective after acute MI in Japanese subjects
Nanotechnology - International nanotechnology shores up European shareholder base
Neurodegeneration - Autoimmunity may be immune defense against degenerative processes
Neurodegeneration - Role of IGF-I signaling in neurodegenerative diseases explored
Neurology - Myelin protein impairs neurological function after spinal cord injury
Neurology - Study shows restless legs syndrome under-diagnosed
Neuromuscular Disorders - Is chemogenetherapy the next step in gene therapy?
Neuroscience - Alterations in tau transcripts correlate with sporadic tauopathy neurofilament
Neuroscience - CXCL12 supports the angiogenesis and cellular cross-talk of glioma
Neuroscience - Enzyme signals help interferon-beta stimulate glioma cell apoptosis
Neuroscience - MRI can locate ataxia-inducing lesions in Miller Fisher syndrome patients
Neuroscience - Oxidative stress elicits differential MnSOD and HO-1 expression
Neuroscience - Retrovirally mediated gas1 expression restricts glioma cell proliferation
Neuroscience - proNGF exhibits neurotrophic activity but is less active than mature NGF
Non-Hodgkin Lymphoma - Extranodal non-Hodgkin lymphoma can occur in the sinonasal tract
Non-Small Cell Lung Cancer - Patients with locally advanced lung cancer benefit from chemoradiotherapy
Obesity - Company acquires rights to the patent for nasal spray treatment for obesity
Obesity - Nastech highlights PYY nasal spray development program
Obesity - Positive safety data presented for obesity treatment
Obesity - Xenical more effective than lifestyle changes alone in overweight adolescents
Obesity Epidemiology - Increasing obesity rates will lead to higher disability rates
Obesity Pathogenesis - Gastrointestinal satiety signals reviewed
Obesity Surgery - Minimally invasive surgery for morbid obesity reviewed
Obesity Therapy - Leptin induces patterns of immediate early gene expression in the brain
Obesity Therapy - Non-imidazole histamine receptor antagonist has anti-obesity effects
Obesity and Diabetes - Weight loss significantly improved metabolic syndrome in obese Koreans
Oncogenesis - Bcl-2 suppresses senescence and programmed cell death
Oncogenesis - Cyclin-dependent kinase 4 may foster liver cancer formation
Oncogenesis - Epithelial metaplasia may be involved in antitumor immunity
Oncogenesis - Many genes synergize with Cbfb-MYH11 to produce acute myeloid leukemia
Oncology - Human prostaglandin F synthase reigns in respiratory and digestive tract tumors
Oncology - Thalidomide treats multiple myeloma by targeting bone marrow angiogenesis
Oncolysis - Peroxisome proliferator activated receptor response elements block cell death
Ophthalmology - Research suggests aspirin helps combat cataracts
Ophthamology - Ocular inflammation treatment on file with FDA
Opioid-Induced Constipation - Methylnaltrexone to move on to phase II trials for opioid-induced constipation
Oral Cancer - Synthetic and natural agents can cause apoptosis in oral cancer cells
Oral Medicine - Fusobacterium nucleatum serine protease identified
Orthopedic Surgery - Prevention of deep vein thrombosis reviewed
Osteoporosis - Gene therapy reverses established osteopenia in ovariectomized mice
Osteoporosis - Risedronate preserves bone architecture in osteoporotic postmenopausal women
Osteoporosis - Website helps parents raise strong daughters
Osteoporosis - sNDA submitted to FDA for once-monthly dose of Boniva
Osteosarcoma - Apo2L/TRAIL and doxorubicin increases sensitivity to bone sarcomas
Ovarian Cancer - Anti-tumor responses induced by ovarian cancer protein characterized
Ovarian Cancer - Chemotherapy after cytoreductive surgery for ovarian cancer beneficial
Pain - Combination liquid pain reliever provides low-level acetaminophen
Pain - Publication urges caution for women seeking OTC pain relief
Pain Management - FDA gives approval for generic morphine doses
Pain Medicine - New developments in treatment of cancer pain reviewed
Pain Medicine - Pre-emptive morphine may contribute to neonate brain damage
Pancreatic Cancer - Clinical trial to study Panvac-VF in advanced pancreatic cancer
Pancreatic Cancer - Inactivation of Men1 gene causes pancreatic and pituitary tumorigenesis
Pancreatic Cancer - Pancreatic islet cell tumors have non-islet origin
Parasitology - Functional genomics for parasitic nematodes and platyhelminths reviewed
Parkinson Disease - Parkinson disease mutations affect axonal transport in cultured neurons
Patent Litigation - Court rules in favor of surgical device company's patent
Patents - Eight U.S. patents granted for high-speed cell analysis platform
Patents - U.S. patent granted for its Immunogene therapy for cancer
Pediatric Cancer - Parental pesticide exposures may be linked to pediatric lymphoma cases
Pediatric Vaccine - Vaccine against six diseases is safe and effective in children
Periodontal Disease - TaqMan PCR assay detects six species of periodontopathic bacteria
Personnel - Biopharmaceutical company announces re-election of board members
Personnel - Biopharmaceutical company appoints new member to board of directors
Personnel - Biopharmaceutical company names new board member
Personnel - Biotech company announces new chairman of the board
Personnel - Dale A. Stringfellow joins biotech company's board of directors
Personnel - Dentist fined for over prescribing medicine leads antidrug group
Personnel - Diagnostics/research company names chief financial officer
Personnel - Immunotherapeutics company appoints Peter Thornton as chief financial officer
Personnel - James Rouse appointed as medical officer at nutraceutical firm
Personnel - Medical advisory board assembled to guide development of CDAD treatment
Personnel - Molecular oncology research company names new board member
Personnel - Orthobiologics company appoints new board member
Personnel - Pharmaceutical company announces resignation of chief development officer
Personnel - Pharmaceutical company appoints new member to scientific advisory board
Personnel - Pharmaceutical company names three new leaders to U.S. executive team
Personnel - Pharmaceutical company names vice president, global sales and marketing
Personnel - Pharmaceutical company's chairman and chief executive officer to retire
Personnel - Specialty pharmaceutical company names vice president and general counsel
Pharmaceutical Development - Generic versions of two drugs receive FDA approval
Pharmaceutical Development - New conference to focus on American and Asian partnerships
Pharmaceutical Development - New report shows that expiring patents may cost pharmaceutical industry $80 billion
Pharmaceuticals - U.S. senior population using Internet for health and pharmaceutical information
Pharmacogenomics - Pharmacogenomics could lower health care costs, investigators report
Pharmacokinetics - Method to measure kinetics of penicillin thermal decomposition reported
Pharmacokinetics - Time-resolved X-ray data can identify protein intermediate structures
Pneumonia - Phase II study results of pulmonary delivery of amikacin presented
Pneumovirus - Molecular genetics and pathogenesis of animal pneumoviruses reviewed
Polio Vaccine - Seroprevalence of poliovirus antibody among children in Korea reported
Polymerase Chain Reaction - Short PNA molecular beacons discriminate nucleotide polymorphisms
Prescription Drugs - Canadian drug plan advances in Oak Creek, Wisconsin
Prescription Drugs - FDA rejects petition on Illinois pilot program to buy Canadian medicine
Prescription Drugs - Few Oklahoma seniors apply for card
Prescription Drugs - Low-income enrollments lagging for Medicare drug cards, Thompson
Prescription Drugs - Meetings to help Medicare beneficiaries choose discount cards
Prescription Drugs - New Hampshire Governor signs preferred drug list bill
Prescription Drugs - West Virginia customers experience prescription delays
Prion Disease - Prion protein undergoes alpha- and beta- cleavages of amino-terminus
Product Launch - Pharmaceutical companies increase staffing between phase III and launch
Prostate Cancer - Androgen deprivation affects thyroid function tests in prostate cancer
Prostate Cancer - Array CGH superior to standard CGH for detection of DNA loss
Prostate Cancer - Choosing hormone therapy for prostate cancer depends on several factors
Prostate Cancer - Epidemiology of prostate cancer outlined
Prostate Cancer - Researchers advocate adjuvant therapy in high-risk prostate cancer
Prostate Cancer - Xanafide clinical trial commences in patients with prostate cancer
Prosthodontics - Diagnostic and surgical template for dental implants developed
Prosthodontics - Utility of conversion partial dentures reviewed
Protein Kinase C - Protein kinase C potentiates duodenal mucosal bicarbonate secretion
Protein Regulation - von Hippel Lindau-hypoxia inducible factor controls COX-2 in the injured liver
Proteomics - Kaposi sarcoma-associated herpesvirus K1 protein stimulates invasion factors
Proteomics - Search for folded proteins in vitro and in silico described
Proteomics - Technique enables efficient production of microchip microdialysis membranes
Proteomics - Transforming growth factor-beta 1 regulates several endothelial cell proteins
Protozoal Infection - CTLA-4 blockage increases resistance to infection with Trypanosoma cruzi
Pulmonary Function - Reduced airway function in infancy associated with persistent wheeze at age 11
Pulmonary Medicine - Downregulated dipeptidyl peptidase IV lets non small cell lung cancer flourish
Quality Assurance - Report shows FDA inspectors found quality-control problems at Wyeth plant
RNA Research - RNA interference-based microarray developed
Radiation Therapy - Quinoxaline 1,4-dioxides potentiate the effects of ionizing radiation
Radiotoxicity - COMP-Ang1 protects endothelial cells from radiation-induced apoptosis
Receptor Studies - Melanocortin 4 receptor behavior characterized
Recombinant Therapy - Newly designed COMP-Ang1 outpaces angiopoietin-1 in angiogenesis assays
Reproductive Medicine - Sperm factor that activates eggs is novel phospholipase C:PLC zeta
Respiratory Disease - New studies focus on overproduction of mucus
Respiratory Medicine - Drug-device combo improves efficiency of pediatric inhalation therapy
Retrovirus - FIV replication in activated CD4+CD25+T cells independent of cell proliferation
Rheumatoid Arthritis - European Union approves Enbrel for expanded use
Rheumatoid Arthritis - Matrix metalloproteinases are targets during experimental arthritis
Ribosome - Decreased repeat lengths encourage transgene stability after transfection
Rotavirus Vaccine - Background risk of intussusception in children reported
Rubella - Rubella virus P90 associates with cytokinesis regulatory protein
Saccharomyces - ESF1 required for 18S rRNA synthesis in Saccharomyces cerevisiae
Salmonella - Salmonella has poor survival but high immunogenicity in resistant mice
Salmonella Vaccine - Immunogenic properties of Salmonella atypical fimbriae determined
Schizophrenia Therapy - Nutrition affects outcome of schizophrenia therapy
Seborrheic Dermatitis - Phase III trial of Sebazole initiated
Skin Cancer - More UVA than UVB fingerprint mutations in basal layer of human squamous tumors
Sleep Disorders - PD-6735 granted Orphan Drug Status for sleep disorders in blind patients
Smallpox - Data supports efficacy of LC16m8 smallpox vaccine candidate
Smallpox Vaccine - Mouse neurotoxicity test for vaccinia-based smallpox vaccines developed
Smallpox Vaccine - Smallpox DNA vaccine protects primates against lethal monkeypox
Staphylococcus Vaccine - Staphylococcal enterotoxin B mutant protein protective in C3H/HeJ mice
Stem Cells - Preclinical studies show that stem cells may reverse diabetes in mice
Stem-Cell Biology - From lung to gut - the Wnt signaling pathway transforms cell fate
Stem-Cell Research - Activated neural stem cells contribute to stroke-induced neurogenesis
Stem-Cell Research - Allogeneic PBSCT is feasible for children with beta/beta and beta/E
Stem-Cell Research - Cord blood stem cells plus fibrin platelet glue used for wound repair
Stem-Cell Research - Developing neonatal rabbit appendix is seeded by immature blood-borne B cells
Stem-Cell Research - Dopaminergic neurons generated from embryonic stem cells
Stem-Cell Research - Embryonic stem cells are an alternate marrow donor source
Stem-Cell Research - GAMT deficiency causes biochemical adaptations in brain and skeletal muscle
Stem-Cell Research - Large defect bone reconstruction using BM-derived SSC not proven for non-union
Stem-Cell Research - Mesenchymal stem cells from adult mouse bone marrow isolated and characterized
Stem-Cell Research - Novel DZIP gene expressed in embryonic stem cells and germ cells is identified
Stem-Cell Research - Nucleosome remodeling defect prevents IL-12(P35) transcription in neonatal DC
Stem-Cell Research - Poly(NiPA-co-AAc) gel may provide optimal chondrocyte propagation 3D environment
Stem-Cell Research - Skeletal muscle differentiation potential of adult BM cells may lead to therapy
Stem-Cell Transplantation - Allogeneic hematopoietic stem cell transplant for lymphoma should be selective
Stem-Cell Transplantation - Predictors of outcome identified in patients with metastatic rhabdomyosarcoma
Streptococcus - Streptococci from infants with invasive disease characterized
Streptococcus Pneumoniae - 99.9% of S. pneumoniae isolates susceptible to Ketek, per surveillance study
Stroke - Protein may identify tPA bleeding risk in ischemic stroke patients
Stroke Prevention - Angiotensin II provides cerebroprotection against stroke
Survival and Mortality - Older breast cancer patients in Canada benefit from early detection
Thrombosis - Pinokinase reduces thrombosis in high-risk individuals on long flights
Tissue Engineering - Cartilage tissue regenerated by serum-free cultured chrondrocyte implantation
Tissue Engineering - Nanocolumns produced for cell culture using colloidal lithography
Tissue Regeneration - FDA issues special protocol assessment approval
Toxicology - Cream may ward off jellyfish stings
Toxoplasmosis - T. gondii-specific recombinant antigens useful for serodiagnosis
Transfusion Medicine - GB virus C/hepatitis G virus infections are rare and self-limiting in India
Transgenics - New transgenic system produces bulk protein
Trypanosomiasis - Cytokine response to T. brucei infection characterized
Tuberculosis Vaccine - Inactivated Mycobacterium bovis BCG vaccine protects against TB
Tumor Development - Neuroblastomas exposed to hypoxia undergo genetic shifts
Tumor Suppression - Adenoviruses bearing gfp-zeocin fusion cassettes select p53-deficient cells
Tumor Suppression - p16 Plasmids control telomerase activity in human gliomas
Tumorigenesis - Acquired periostin expression promotes breast cancer angiogenesis
Type 1 Diabetes - Esophagus stiffens in experimental type 1 diabetes
Type 1 Diabetes - Insulin detemir lessens blood glucose variability in study
Type 2 Diabetes - Repaglinide outperforms nateglinide in type 2 diabetes study
Ultrasonography - Ultrasound affects structure and function of proteins of PPSB complex
Urology - The benefits of radical prostatectomy extend beyond cancer control
Vaccine Adjuvant - Cell death induced by vaccine adjuvants containing surfactants
Vaccine Development - Inflammatory cytokines overcome age-related defects in T-cell responses
Vaccine Development - Tumor necrosis factor autovaccination eliminates melanoma metastasis
Vaccine Research - New licensing agreement to create therapeutic vaccine platform
Vaccines - DNA system to support research on vaccine devlivery
Vascular Development - p68RacGAP interactions modulate the formation of capillaries
Vascular Treatments - Medical device manufacturer receives two FDA marketing clearances
Vector Development - Adenovirus vector targets cells expressing junctional adhesion molecule
Vector Development - Amphiphilic cyclodextrins enhance transgene expression
Vector Development - Bone cancer cells respond to HSV thymidine kinase-ganciclovir gene therapy
Vector Development - T-cell response to adenovirus hexon and DNA-binding protein in mice
Viral Disease - Biotech company testing possible antidote for bioterrorism viruses
Viral Genomics & Genetics - Two subtypes of hepatitis B virus genotype B flourish in Japan
Viral Genomics and Genetics - New hepatitis C virus models will expand research possibilities
Virology - Hepatitis C virus suppression of IRE1-XBP1 promotes viral persistence
Virology - Human Coronavirus 229E in nasal specimens detected by RT-PCR hybridization assay
Virology - Viruses appropriate apoptotic and NF-kappa B signaling pathways
Vitiligo - Efficacy of 308-nm xenon-chloride excimer laser clarified
Vulvovaginal Candidiasis - Positive results reported from CZEN-002 trial for vulvovaginal candidiasis
Wound Care - Insulin-like growth factor-I alters the effects of thermal trauma in rats
Wound Treatment - LAM Pharmaceutical accelerates Central American product launch
Yersinia - Nuclear targeting signal in YopM from Yersinia species identified
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