Susan Hasty, Publisher
Table of Contents . . . July 2nd, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Anemia - Special protocol assessment agreed on for approval-enabling study of Ranexa
Breast Cancer - Application filed for European marketing approval of RSR13 (efaproxiral)
Cancer Therapy - Ceplene 36-month malignant melanoma survival data published
Depression - Study links chromium picolinate supplementation, reduced carbohydrate cravings
Acute Bipolar Mania - Risperdal reduces acute bipolar mania symptoms as early as day 3 of treatment
Acute Coronary Syndrome - Millennium, partner begin trial with INTEGRILIN (eptifibatide) Injection
Acute myeloid leukemia - Fusion proteins overcome the hurdle of leukemia cell chemoresistance
Addiction Medicine - Liver function test results for naltrexone patients may be misleading
Adenovirus - Actin and its C-terminal peptide act as cofactors with adenovirus proteinase
Age-Related Macular Degeneration - SnET2 NDA accepted by FDA with priority review designation
Age-Related Macular Degeneration - Study will investigate safety, efficacy of PFTA as adjunct to Visudyne therapy
Allergy Medicine - Allergy vaccine disrupts structure of calcium-binding allergen
Allergy Medicine - Cytochrome P450 isoforms involved in oxatomide metabolism identified
Allergy Medicine - Lung proteome within airway mucosa following allergen challenge investigated
Allergy Medicine - Nanocrystalline silver cream potentially therapeutic for skin inflammations
Allergy Medicine - Total IgE measurement is valid surrogate for antigen-specific IgE
Alzheimer Disease - AApoAII amyloidosis induced by various heterogeneous amyloid fibrils
Alzheimer Disease - CD36 overexpression correlates with A-beta, not with Alzheimer disease
Alzheimer Disease - Neurodegeneration and amyloid plaques occur in transgenic Drosophila
Alzheimer Disease - Olfactory dysfunction occurs in mice overexpressing human tau protein
Alzheimer Disease - Oxidative stress and mitotic changes necessary for Alzheimer disease progression
Alzheimer Disease - Seeding specificity in amyloid growth induced by heterologous fibrils
Amyotrophic Lateral Sclerosis - Link suspected between soccer and amyotrophic lateral sclerosis
Angiographic Imaging - Study initiated for ferumoxytol under company's agreements with NCI
Angiology - Platelet-derived growth factor stimulates pericyte recruitment to tumors
Anthrax - NIH supports phase I clinical trial of DNA-based anthrax vaccine
Anthrax - Public-private partnership extends Dutch-American cooperation in biodefense
Anthrax Vaccine - B. anthracis antigens for testing anthrax immunity identified
Anti-Infectives - Antimicrobial drug development declining
Anti-Infectives - Thyroliberin controls murine candidosis
Antibiotics - Development and marketing agreement signed for novel formulation of amoxicillin
Antifungal Agents - New antifungal agents offer prospects for treatment
Apoptosis - PIDDosome activates caspase-2 in response to genotoxic stress
Arthritis Therapy - Short-stemmed modular shoulder prosthesis safe and effective
Artificial Heart - Diaphragm patch facilitates placement of AbioCor implantable replacement heart
Attention Deficit/Hyperactivity Disorder - Strattera provides full-day relief from ADHD symptoms in systematic study
Attention-Deficit Hyperactivity Disorder - Strattera now available in the United Kingdom
Autoimmune Disease - Link between vaccinations and autoimmune disease reviewed
Autoimmune Disease - MFG-E8 mediates removal of apoptotic germinal center B cells
Awards - Biotechnology company named on list of technology industry's top 100 companies
Bacillus - Mosquito-larvicidal toxin produced by Bacillus sphaericus crystallized
Bacteria - Viral Antigens enters strategic collaboration
Bartonella - Diversity of Bartonella in rodents of Thailand determined
Bioengineering - Collagenous matrices release exogenous growth factors for tissue regeneration
Biotechnology - Albumin-containing sol-gel glasses developed
Biotechnology - Four pH-dependent formation constants for free PSA elucidated
Biowarfare - Vaccines for the prevention of diseases caused by potential bioweapons
Bipolar Disorder - Seroquel combined with mood stabilizer may improve mania symptoms
Blood Glucose - Accuracy of blood glucose estimation by children with diabetes studied
Blood Vessel - Company announces new intravenous gene-delivery method
Bone Repair - Calcium and thrombin trigger factors that spark endothelial cell proliferation
Bowel Incontinence - Secca clinical patient registry for bowel incontinence treatment
Brain Injury - Relation between stress and circulating levels of S100B protein reported
Breast Cancer - Follow-up data presented on autologous hemoderivative vaccine
Breast Cancer - Nanoparticle form of paclitaxel is active in patients who failed taxane therapy
Breast Cancer - Researchers develop better understanding of tamoxifen resistance
Breast Cancer - Survivin, Bcl-2, p53 and bax expression increased in breast carcinoma
Breast Cancer - Vaccine containing multiple antigens generates higher immune response
Breast Cancer - Women treated for breast malignancies receive poor postoperative education
Breastfeeding - FDA warns against women using domperidone to increase milk production
Business Update - Bridge Pharmaceuticals Corporation launched
Business Update - Company acquires rights to novel proteasome inhibitors and related technology
Business Update - Company opens new preclinical pharmaceutical inhalation facility
Business Update - Company to acquire controlling interest in HBBenda
Business Update - Drug discovery company announces completion of two validation milestones
Business Update - Hospira expands manufacturing capacity
Business Update - ImClone shares jump on favorable data on cancer drug
Business Update - Integrated BioPharma delivers update on paclitaxel API
Business Update - Nutraceutical/pharmaceutical company selects Central American distributor
Business Update - Pharmaceutical firm announces move to new facility
Business Update - Pharmaceuticals firm acquires two new drugs for ADHD, completes financing
Business Update - SEC finds Schering-Plough unit made bribes through charity
Business Update - Stem cell company announces plans for new facility
Business Update - Strategic Alliance formed for pulmonary delivery technologies
Cachexia - Lipid-mobilizing factor protects tumor cells from oxidative damage
Caffeine - Mechanism of caffeine as psychomotor stimulant proposed
Cancer Biomarker - Epidermal growth factor receptor and Cerb-B2 fail to predict tongue cancer
Cancer Epidemiology - Men with vitamin D receptor polymorphisms are at risk for prostate cancer
Cancer Genomics and Genetics - Role of hMLH1 and HPP1 in adenocarcinomas determined
Cancer Prevention - Cancer risk lowered in those taking statins to prevent heart attacks
Cancer Prevention - Warfarin does not prevent bladder cancer formation
Cancer Prognosis - Calcitonin gene hypermethylation marks the progress of leukemia
Cancer Risk Factor - Familial tooth agenesis signals the risk for colorectal cancer
Cancer Risk Factor - Genetic shifts emerge during hepatitis C virus-linked carcinogenesis
Cancer Screening - U.S. National Cancer Institute in vitro drug screening has expanded
Cancer Suppression - Disrupted STAT3 signaling opens the door to tumor cell invasion
Cancer Therapy - ADVEXIN and INGN 241 featured at international scientific conference
Cancer Therapy - Alternating electric fields have potent antitumor activity
Cancer Therapy - Biomarker predicts response of colon cancer patients to chemotherapy regimen
Cancer Therapy - CMS and NCI collaborate to bring new drugs, better treatment to cancer patients
Cancer Therapy - Celecoxib is a potent chemopreventive agent
Cancer Therapy - Clinical safety, efficacy data of Advexin featured at scientific meeting
Cancer Therapy - Companies end Genasense expanded-access program in melanoma
Cancer Therapy - Drug treatment first big improvement in brain cancer in decades
Cancer Therapy - Endothelial cell-specific human antibodies might retard tumor growth
Cancer Therapy - Gene therapy tested to protect bone marrow during chemotherapy
Cancer Therapy - Hsp90 inhibitors enhance complement-induced tumor cell lysis
Cancer Therapy - Liver cancer expert presents new data on SIR-Spheres
Cancer Therapy - Loco-regional interferon after tumor irradiation regresses metastatic melanoma
Cancer Therapy - M2BP-derived CTL epitopes with possible use in cancer immunotherapy identified
Cancer Therapy - Near-infrared labeled endostatin localizes at tumors in animal models
Cancer Therapy - PTK/ZK completes enrollment for phase III metastatic colorectal cancer trial
Cancer Therapy - Patients' genes may influence how they experience fatigue and quality of life
Cancer Therapy - Phase I trial for anticancer compound Xl647 initiated
Cancer Therapy - Preclinical drug studies in rodents can predict phase I starting dose
Cancer Therapy - Researchers show potential of fighting angiogenesis
Cancer Therapy - Some drugs effective in rodent tumor models fail to perform clinically
Cancer Therapy - When combining new oral agents with standard chemotherapy, timing may be crucial
Cancer Treatment - Genetic differences explain severity of chemotherapy side effects
Cancer Vaccine - Antitumor immunity determined by the tumor not vaccine
Cancer Vaccine - B7-2 expression elicits anti-tumor immunity in B-cell lymphoma
Cancer vaccine - Cross-talk between dendritic and NK cells examined
Carcinogenesis - DNA methylation of integrin alpha 4 gene supports gastric cancer formation
Cardiac Monitoring - U.S. patent issued for methods and systems for processing ECGs
Cardiac Safety Monitoring - $1M study awarded for cardiac safety monitoring, information distribution
Cardiovascular Disease - Implantable defibrillator effective against hypertrophic cardiomyopathy
Cell Biology - Bead-based assay is a poor model of apoptotic cell phagocytosis
Central Nervous System - Regulation of myelin proteolipid protein gene expression reviewed
Cervical Cancer - SOC1 inhibits HPV-E7-mediated transformation via degradation of E7 protein
Charcot-Marie-Tooth Disease - New locus for Charcot-Marie-Tooth disease type 2 maps to chromosome 12q24
Chemotherapy - Oral RDP58 permits CPT-11 dose escalation and relieves gastric tract toxicity
Chronic Hepatitis C - Cellular compartmentalization is a trait of hepatitis C virus-host interactions
Chronic Liver Disease - A four-step model outlines the progress of non-alcoholic steatohepatitis
Clinical Studies - Company initiates Diquafosol phase III dry eye trial
Clubfoot - Clubfoot with survival of motor neuron 1, telomeric gene deletion reported
Collaboration - Collaborative services agreement expanded by microarray company
Collaborations - Agreement signed for development of phase I HDAC inhibitor for cancer
Collaborations - Agreement signed with Althea Technologies for gene expression technology
Collaborations - Biotech firms conclude agreement regarding manufacturing of cancer drug
Collaborations - Company begins exploratory collaboration with Novartis Institutes
Collaborations - Contract signed with Lockton Companies to control healthcare costs
Collaborations - Development of a Centocor therapeutic protein candidate advances
Collaborations - Distribution deal signed for Aeroneb Professional Nebulizer System
Collaborations - Dutch biopharma enters collaborative agreement with NMRC
Collaborations - Iconix announces chemogenomics collaborative relationship
Collaborations - Joint venture to target cardiac repair
Collaborations - License agreement completed for worldwide rights to hepatitis B product
Collaborations - Manufacturing, commercial rights to trandolapril acquired from Aventis
Collaborations - Sports medicine/exercise group joins Indiana's life sciences initiative
Collaborations - Systems biology company enters licensing agreement with Invitrogen Corp.
Colon Cancer - Eloxatin study demonstrates benefit over standard colon cancer therapy
Colorectal Cancer - Avastin study shows extended survival in metastatic colorectal cancer patients
Colorectal Cancer - Cytochrome C depletion intensifies the immunogenicity of colon cancer cells
Complementary & Alternative Medicine - Salicin derivatives from H. cochinchinensis have antiviral activity
Complementary and Alternative Medicine - Many cancer patients turn to complementary therapies for healing
Constipation - SennaPrompt introduced for overnight relief of constipation
Coronary Angioplasty - FDA does not approve application to amend existing Angiomax label
Coronary Artery Bypass Surgery - Fatal complications after symmetry aortic connector use described
Coronary Artery Bypass Surgery - Pre-op IgG therapy facilitates off-pump CABG in ITP patient
Coronary Artery Disease - Clinical trials of invasive coronary interventions have unanswered questions
Cosmeceutical Trends - Merging health and beauty trends drive cosmeceutical growth
Critical Care Medicine - Detector-induced acute endotracheal tube occlusion reported
Critical Care Medicine - Management of postintubation stenoses in children reviewed
Crohn Disease - Diffuse alveolar hemorrhage reported after infliximab therapy
Cytomegalovirus - CMV viral load can guide clinical management of transplant recipients
Cytomegalovirus - Human cytomegalovirus large terminase subunit pUL56 characterized
DNA Damage - Attenuated p53 response in preneoplastic lesions growth advantage under stress
DNA Manufacturing - Company announces DNA fermentation breakthrough
DNA Repair - DNA double-strand break repaired by homologous recombination
DNA Research - Melatonin protects against oxidative stress in Chinese hamster B14 cells
DNA Research - XPC protein plays key role in cell cycle regulation during cisplatin treatment
Dendrites - Dendritic guidance reviewed
Dengue Fever - IgG1 antibody for neutralization of dengue type 4 virus identified
Dengue Virus - Neugene antisense shows inhibition of tropical virus
Depression - Study: Brain monitoring predicts treatment response in depressed patients
Diabetes Epidemiology - Prevalence of diabetes in the province of Girona, Spain reported
Diabetes Genomics and Genetics - IRS1 variant linked to type 1 diabetes in families from U.S. and U.K.
Diabetes Pathogenesis - Deficiencies in gut NK cell number and function precede diabetes onset
Diabetes Pathogenesis - Helper requirements for effector CTL to beta cell antigens outlined
Diabetes Pathogenesis - Insulin-like growth factors and pancreas beta cells reviewed
Diabetes Pathogenesis - Transcriptional networks controlling beta cell function identified
Diabetes Pathogenesis - pdx1 and HNF6 play roles in proliferation of endocrine precursors
Diabetes Therapy - Alliance to identify factors important to stem cell differentiation
Diabetes Therapy - Diabetes care and complications in remote health care setting described
Diabetes Therapy - Diabetes prevention using transgenic plants requires GAD and IL-4
Diabetes Therapy - Oral amino acids constitute metabolic therapy in patients with diabetes
Diabetes Therapy - Regenerated islets to be used to create supply for diabetes treatment
Diabetes Therapy - Sucanon marketing agreement signed for Mexico
Diabetes Therapy - Ticlopidine beneficial for hypercoagulability in diabetic patients
Diabetes Therapy - Treatment of type 1 diabetes by preserving insulin secretion reviewed
Diabetic Nephropathy - Glucose regulates glomerular endothelial cell proteoglycans
Diabetic Nephropathy - Streptozotocin injections cause early onset of glomerulosclerosis
Diagnostics - ELISA for glial fibrillary acidic protein developed
Diagnostics - Human urine contains colorectal cancer detection markers
Diagnostics - Novel immunoassay devised for HM-1 killer toxin measurement
Diagnostics - Reactivity of yeast phase lysate Blastomyces antigens compared
Diagnostics - Synthetic peptide ELISA for rubella virus neutralizing antibodies effective
Diet and Nutrition - Effect of fiber types on digestibility of nutrients in cats reported
Diet and Nutrition - Food restriction reduces age-related sensitivity to oxidized lipids
Disease-Management Trends - Report explores adoption of pharma company's disease management programs
Drug Addiction - Probuphine effective in clinical trial as opiate addiction treatment
Drug Benefits - Even among those who need them most, statin prescriptions go unfilled
Drug Compliance - Improving patient adherence integral to expanding antipsychotic market
Drug Delivery - Budesonide precipitation conditions affect aerodynamics
Drug Delivery - Carrageenan-based delivery of ophthalmic drugs shows promise
Drug Delivery - Degarelix-loaded PLGA microparticles may enhance prostate cancer treatment
Drug Delivery - Endothelial proteins accessible to drugs injected intravenously
Drug Delivery - Flow cytometry useful for measuring PLG microsphere protein loading
Drug Delivery - New polymer technologies introduced for site-specific drug delivery
Drug Delivery - Percutaneous intra-arterial catheter implantations transport liver cancer drugs
Drug Delivery - Researchers win Kaye prize for gastro-retentive sustained-release system
Drug Delivery - Uniform microspheres for drug delivery devised
Drug Development - Bispecific antibody shows promise as lymphoma therapy
Drug Development - Immunomodulatory activity of FIP-fve protein characterized
Drug Development - Immunomodulatory flavone glucosides isolated from Pleioblastus amarus
Drug Development - Immunomodulatory oxazolone derivatives synthesized
Drug Development - Multicellular tumor spheroids model HSVtk/ganciclovir systems in vitro
Drug Development - Puupehenone and associated compounds are angiogenesis inhibitors
Drug Development - Recombinant anti-MUC1 scFv has improved stability
Drug Discovery - FLIPR Tetra launched; offers 1536 kinetic measurements simultaneously
Drug Manufacturing - Pharmaceutical firm commences cGMP manufacturing of Thiovir
Drug Resistance - Bleomycin resistance stems from faulty transport mechanisms
Drug Resistance - Downregulated Bcl-2 or xIAP enhances the efficacy of breast cancer chemotherapy
Drug Resistance - Wild-type p53 polymorphisms anchor chemotherapeutic response
Emergency Medicine - University awarded patent for "date rape" drug test
Employee Health - ThedaCare, pharma, collaborate on employee health and productivity initiative
End-stage Liver Disease - De novo liver cancer in liver transplant candidates warrants list advancement
Endocrinology - Aldosterone signals modify bone marrow endothelial cell organization
Endocrinology - Hypothalamic glutamate decarboxylase expression cuts rodent feeding behavior
Endocrinology - Selenoprotein SelS is novel glucose-regulated protein
Endocrinology - Synthetic hormone in contraceptives, HRT causes negative effects in monkeys
Endocrinology - Vitamin D-mediated prostate cancer inhibition requires androgen signals
Environmental Health - MS method to measure toxaphene congeners in human serum developed
Environmental Health - Novel assay provides rapid detection of 2,4-D and simazine pesticides
Enzyme Stabilization - Water-based buffer for enzyme stabilization, storage available
Enzymology - Histone deacetylation is involved in ras-induced suppression of RECK
Enzymology - Nitric oxide is a negative regulator of endothelial cell migration
Epidermolysis Bullosa - Thymosin Beta 4 receives Orphan Drug designation for Epidermolysis Bullosa
Epilepsy - Anti-epilepsy drugs can increase rate of bone loss in older women
Epilepsy - Study confirms that Keppra provides opportunity for patients to be seizure free
Erosive Esophagitis - Prevacid IV for Injection approved by the FDA for erosive esophagitis
Eye Cancer - New laboratory model can be used to test new treatments for pediatric eye cancer
Fibrinolysis - Plasma D-dimer identifies lymph node metastasis in breast cancer patients
Finance - American Stock Exchange lists common stock of islet transplantation firm
Finance - Antimicrobial-drug company announces exercise of over-allotment option
Finance - Cancer immunotherapies company announces closing of public offering
Finance - Cancer vaccine maker reports $1M net loss
Finance - Chinese biotech firm issues update on AMEX listing
Finance - Company focused on lipids announces sale of real estate assets totaling $5.4M
Finance - Diagnostics company files secondary registration statement
Finance - Disposables supplier reports record fourth quarter net income
Finance - Drug discovery firm completes series D financing
Finance - Eye-disease focused company completes secondary public offering
Finance - Increase in number of authorized shares of stock approved at pharmaceutical firm
Finance - MRI pharmaceuticals company prices $75M offering
Finance - Milestone payment issued from Amgen as part of drug R&D deal
Finance - Ophthalmics company's stockholders approve $16.5 million financing
Finance - Ophthalmology company increases stockholders' equity through debt reduction
Finance - Oral insulin developer retains financial advisory firm
Finance - Pain therapy device firm announces stock repurchase plan
Finance - Pharmaceutical R&D company completes $55M Series D financing
Finance - Pharmaceutical company reports loss of $0.69 per share
Finance - Transfusion company announces 3-for-2 stock split and stock repurchase program
First Aid - SEAL-ON launched; designed to stop bleeding fast
Food-Borne Illness - E. coli O157:H7 outbreak linked to salami in British Columbia
Food-Borne Illness - Bioassay suitable for screening of enrofloxacin residues in chicken
Food-Borne Illness - LC/MS analysis of brevetoxin metabolites in Eastern oyster reported
Fungal Infection - Voriconazole may prevent fungal relapse during at-risk periods of leukemia
Gastroenterology - Aurora-2 is a potential target for the treatment of pancreatic cancer
Gastroenterology - Clofazimine in lipiodol diminishes liver tumors in rodent cancer models
Gastroenterology - Diagnosis of gastroesophageal reflux disease reviewed
Gastroenterology Vaccine - Progress in enteric vaccine development outlined
Gastroesophageal Reflux Disease - Stretta procedure highly effective for GERD in obese patients, data shows
Gene Expression - Heterochromatin protein-1 affects dynamics of heterochromatin maintenance
Gene Therapy - New research on the progress of gene therapy presented at meeting
Gene Transfer - A new quantitative method measures the magnitude and volume of transgenes
Gene Transfer - NK4 transfection generates several modes of antitumor activity
Generic Drugs - Metronidazole Cream 0.75% introduced
Genetic Disorder - Aminoglycoside rescues disease-causing mutation in vasopressin receptor gene
Genetic Engineering - Administration route shapes the effects of IL-12-expressing dendritic cells
Genetic Mutation - Germline mutations in Chernobyl cleanup workers' offspring are modest
Genetics - Company adds cell-based knockins to its vector application services
Genomics - FDA, NIH drive clinical genomics: Is widespread application in the near future?
Genomics - Pharmacogenomic profiling of PI3K/PTEN-AKT-mTOR pathway in tumors elucidated
Genomics and Genetics - 5' nuclease assay with minor groove binder probes effective
Genomics and Genetics - Cryptic 6q subtelomeric deletion characterized
Genomics and Genetics - Myc-associated zinc finger protein activates murine RAG-2 promoter
Genomics and Genetics - Stress-induced cellular gene expression characterized
Geriatrics - Plasmid-based hormone therapy could improve disease or age-induced wasting
Growth-Hormone Deficiency - Companies agree to discontinue commercialization of Nutropin Depot
Guillain-Barre Syndrome - Mutations in CD14 or TLR4 not linked to GBS risk
Gynecology - Bikunin plus paclitaxel trims tumor burden and ascites in ovarian cancer models
HARS - Phase III trial to study Serostim as treatment, maintenance therapy for HARS
HIV & Cancer - EBV may play role in pathogenesis of head and neck cancers in HIV infection
HIV/AIDS - Co-administration of lopinavir decreases amprenavir concentration
HIV/AIDS - RNAi is gene-specific therapeutic option to control HIV-1 replication
HIV/AIDS Genetics - Mutations at position 184 of HIV-1 RT affect virus titer and viral DNA synthesis
HIV/AIDS Pathogenesis - HIV-1 Vpr promotes ubiquitination and turnover of Vpr mutants
HIV/AIDS Prevention - Misconceptions regarding condom use have implications for HIV prevention
HIV/AIDS Research - Atazanavir and tipranavir quantified in plasma by HPLC plus MS/MS
HIV/AIDS Research - Conserved bulky hydrophobic residues help stabilize HIV gp120-gp41 complex
HIV/AIDS Research - Major 5' site mutation renders CMV-driven HIV-1 proviral clone Tat-dependent
HIV/AIDS Research - Unusual ''senseless'' 2',5'-oligoribonucleotide has potent anti-HIV activity
HIV/AIDS Therapy - Research agreement renewed for development of novel HIV entry inhibitors
HIV/AIDS Therapy - Single-dose phase I trial of first-in-class HIV maturation inhibitor completed
HIV/AIDS Treatment - Antiretroviral therapy adherence issues are elucidated
HIV/AIDS Treatment - Drug interactions occur between opioids and antiretroviral medications
HIV/AIDS Treatment - Sociocultural barriers impede complementary and alternative medicine use for HIV
HIV/AIDS Treatment - Vif-resistant mutant APOBEC3G may provide gene therapy approach to HIV infection
HIV/AIDS Virology - Virologic failure in HIV patients associated with poor adherence to NNRTIs
Head and Neck Cancer - STK15 polymorphism correlates with esophageal squamous cell cancer occurrence
Healthcare Coverage - ACCC calls on CMS to allow for exceptions to ASP reimbursement
Healthcare Market - Survey reflects positive outlook for healthcare industry for remainder of 2004
Hearing Loss - Ceptor Corporation receives grant for hearing loss study
Heart Attack - Genetic markers linked to increased risk of heart attack
Heart Surgery - Bivalirudin superior to heparin for thrombosis prevention
Heart Surgery - Expanded pouch enables safe intra-abdominal placement of Novacor device
Heart Surgery - Novel technique devised for pediatric mitral valve annuloplasty
Heart Surgery - Stenting can enhance treatment for cervical artery dissection
Helicobacter - H. pylori-specific antibodies counteract resistance against infection
Hematology - 1,8-Anilinonaphthalene sulfonate binds to central cavity of human hemoglobin
Hematology - Low-molecular-weight heparins may interfere with tumor growth and metastasis
Hemophilia - Foundation says it's not deterred by Avigen gene-transfer therapy announcement
Hemophilia - Immunosuppressive therapy can rapidly resolve acquired postpartum hemophilia
Hemorrhagic Fever - West Nile virus trial expands to include additional lethal viruses
Hepatitis B Virus - Low-level viremia of hepatitis B found in antibody-positive blood donor
Hepatitis C - Genetic vaccine promising against chronic hepatitis C
Hepatitis C Vaccine - Vaccine encoding hepatitis C antigens elicits specific immune response
Hepatocellular Carcinoma - Selective resection margins attempt to contain liver cancer micrometastases
Hepatology - Cancer drugs and irradiation combine to overcome liver cancer proliferation
Hepatology - Expression of CYP3A4 mRNA correlates with metabolic activity in human liver
Hereditary Angioedema - FDA permission granted to resume DX-88 clinical trials
Hip Replacement - Bone sialoprotein-coated femoral implants subject to loosening
Hip Replacement - Creep is main component of fatigue damage at cement-bone interface
Hip Replacement - Taper-design uncemented femoral stem may reduce bone loss
Hodgkin Disease - B7-2 protein levels reduced in HD tumor cells
Hormone Replacement Therapy - Long-term tibolone therapy appears to benefit lipid profile
Hypercholesterolemia - U.S. FDA grants tentative approval to market fenofibrate tablets
Hypertension - North American licensing strategy outlined for Thelin
Hypogonadism - Misrouted cell surface GnRH receptors contribute to hypogonadism
Idiopathic Thrombocytopenic Purpura - ITP study finds Gamunex safe and efficacious for patients
Immune Thrombocytopenic Purpura - Rituximab safe and effect for ITP treatment
Immunology - 4-1BB signaling plays key role in regulatory T-cell function
Immunology - Actin cytoskeleton suppresses basophil signaling
Immunology - Alpha-actinin recruits SPA-1 to immunological synapse
Immunology - Antibodies against enterococcal bacteriocin enterocin P evaluated
Immunology - CD28 costimulation triggers tumor recognition by modified T cells
Immunology - CD45 isoform expression compared in T-cell subsets
Immunology - CXC chemokines forge a link between inflammation and angiogenesis
Immunology - Cell-line company adds Dr. Stephen Chang to scientific advisory board
Immunology - Cytosolic phospholipase A2 alpha targets the phagosome membrane
Immunology - Dihydropyridine receptors are selective markers of Th2 cells
Immunology - Fc receptor aggregation has inhibitory effect on pre-B cells
Immunology - Generation of distinct CD8+ memory T cell subsets is CD40L-dependent
Immunology - Hepatitis C virus clears despite immunosuppression after liver transplantation
Immunology - Immunoenhancing effects of bovine glycomacropeptide characterized
Immunology - Impaired IL-18 release activated with protein I/II
Immunology - Interferon-gamma attenuates interferon-alpha activity in liver cells via STAT1
Immunology - Interleukin-6 obstructs T cell-mediated hepatitis
Immunology - Mannose 6-phosphate receptors not involved in granzyme-mediated cytotoxicity
Immunology - Maternal IgG appears phenotypically in offspring as non-genetic inheritance
Immunology - NIH awards phase II SBIR to develop zebrafish apoptosis drug-screening assays
Immunology - Novel assay detects different forms of IFN-gamma in single NK cells
Immunology - Results on electroporation-enhanced DNA vaccine delivery presented at meeting
Immunology - Role of IL-10 in skin disease pathogenesis and/or treatment reviewed
Immunology - StcE may protect E. coli O157:H7 and host cell from complement-mediated lysis
Immunology - T cells from elderly adults respond to stimulation with IL-2 production
Immunology - TRX and MIF/GIF proteins have cysteine-dependent immune regulatory activity
Immunology - There are two sides of the antitumoral activity of imiquimod
Immunotherapy - Lorus announces European patent to protect unique tumor suppressor
Immunotherapy - R&D company licenses rights to proinflammatory cytokine receptor antagonists
Infection - Antimicrobial impregnated catheters demonstrate efficacy and cost effectiveness
Infectious Disease - C. parvum enterocyte infection may affect expression of defensins
Infectious Disease - Candidemia documented in wide range of patient populations
Infectious Disease - Early NO inhibition augments HSV-1 intranasal infection
Infectious Disease - IFN-gamma production during RSV infection is not associated with IL-12 or -18
Infectious Disease - Incidence of methicillin-resistant S. aureus infection high in prison population
Inflammation - Enzyme linked to inflammation reduced in mouse study
Inflammatory Bowel Disease - 4-ASA enemas well-tolerated by patients with 5-ASA-induced pancreatitis
Inflammatory Bowel Disease - DSS load affects colitis severity in mice
Influenza Vaccine - Influenza A vaccine based on M2 domain provides weak protection
Influenza Vaccine - Splenectomized patients have normal response to influenza vaccine
Influenza Virus - Fate of 130 hemagglutinins from different influenza A viruses determined
Insulin - EU approves Levemir, a long-acting insulin analog
Insulin Delivery - In vitro degradation of insulin-loaded nanoparticles reported
Insulin Delivery - Nanoparticle-based oral insulin study data published
Kidney Cancer - Treatment shows promise for aggressive kidney cancer
Kidney Transplantation - TGF-beta1 production is activated in kidney transplant recipients
Knee Replacement - Image-based and non-image-based navigation systems compared
Knee Replacement - Revision total knee arthroplasty safe and effective
Knee Replacement - Total knee replacement alters knee and hip joint kinematics during stair climbing
Leber Congenital Amaurosis - Abolished interaction of NUB1 with AIPL1 linked to Leber congenital amaurosis
Legal Issues - $272,000 released to Pennsylvanians for Taxol and paclitaxel purchases
Legal Issues - Is GSK guilty of fraud?
Legal Issues - Pharmaceutical company reaches agreement with Texas Attorney General's Office
Leptin Studies - Leptin released within brain at increased rate in obese humans
Leptin Studies - Leptin-leptin receptor interactions have 1:1 stoichiometry
Leukemia - FDA begins priority review of NDA for clofarabine in pediatric acute leukemia
Leukemia - Hydroxyurea may cause acute leukemia in patients with sickle cell disease
Liver Metastases - Hepatic artery infusion has high partial response but no longevity benefit
Lung Cancer - The 5-fluorouracil derivative UFT foils non-small cell lung cancer angiogenesis
Lung Transplantation - Diagnostic utility of Platelia Aspergillus galactomannan antigen determined
Lymphoma Therapy - T-cell dysfunction characterized in chemotherapy-treated lymphoma patients
MMR Vaccine - Economic analysis of two-dose MMR vaccination program in U.S. reported
MMR Vaccine - Measles-mumps-rubella vaccination recommended at 12 to 15 months of age
Market Analysis - 38% of pharma companies involve thought leaders in clinical trial kick-offs
Market Analysis - Benchmarks the pharmaceutical market research function analyzed
Market Analysis - Biological response modifiers' image dominates arthritis therapies despite price
Market Analysis - Biotech loses ground in May as the economy stalls and the IPO market softens
Market Analysis - New product planning, strategic alliances drive pharmaceutical success
Measles Epidemiology - Epidemiology of measles in the United States from 1997-2001 reported
Measles Epidemiology - Minimum investigation rate for evaluating measles monitoring proposed
Measles Epidemiology - Surveillance is adequate to detect endemic measles in the U.S.
Measles Survival and Mortality - Acute measles mortality in the United States during 1987-2002 reported
Measles Survival and Mortality - Measles hospitalizations during 1985-2002 in U.S. reported
Measles Vaccine - Disparity in measles vaccine coverage in minority children eliminated
Measles Vaccine - Vaccination levels associated with lack of measles in preschoolers
Measles Vaccine - Vaccine-induced antibodies to measles persist 26 to 33 years
Measles Virus - Genetic analysis of measles viruses in U.S. performed
Measles Virus - Measles elimination in U.S. aids global measles elimination efforts
Measles Virus - Measles virus shedding does not occur with inapparent measles infections
Medical Devices - Utility of several differet types of latex immunoassay particles compared
Medical Ethics - Ethics of vaccine research reviewed
Medicare - Initiative helps low-income beneficiaries sign up for drug discount card
Medication - Brand medications preferred over generics for serious conditions, survey shows
Melanoma - FDG-PET not suitable for lymph node metastasis testing
Melanoma - Topical imiquimod immunotherapy effective for amelanotic lentigo maligna
Melanoma Vaccine - Targeting melanoma inhibitor of apoptosis protein destroys tumors
Meningitis - Unique variant of disease-causing meningococci characterized
Meningitis Vaccine - New Neisseria meningitidis candidate vaccine identified
Mergers and Acquisitions - Advanced Bionics acquired for $740M in cash
Mergers and Acquisitions - Agreement in principle signed to acquire MJ Research
Mergers and Acquisitions - Biotechnology companies enter definitive merger agreement
Mergers and Acquisitions - Genesis Bioventures enters into strategic agreement
Mergers and Acquisitions - Genomics Collaborative acquired through stock deal
Mergers and Acquisitions - IVAX acquires Peruvian pharmaceutical company
Mergers and Acquisitions - Majority interest acquired in $10M Chinese company
Mergers and Acquisitions - Merger produces pipeline of products for serious infectious diseases
Mergers and Acquisitions - Merger to develop advanced molecular diagnostics for personalized medicine
Metastasis - Hyperthermic antiblastic perfusion curtails locoregional limb melanoma
Metastasis - SIKVAV retro and retro-enantio analogues take aim at metastatic events
Metastasis - The aggressive nature of insular carcinoma calls for total thyroidectomy
Metastatic Cancer - MGB1 differentiates metastasized breast cancer from primary lung lesions
Microencapsulation - Particle characteristics affect transcutaneous vaccine delivery
Migraine - FDA issues not-approvable letter for MT 100 migraine treatment
Monoclonal Antibody - Monoclonal antibodies captured using hydrophobic interaction chromatography
Mucopolysaccharidosis VI - Positive phase III data reported on Aryplase for MPS VI
Multiple Myeloma - Thalidomide Pharmion application to be resubmitted to EMEA for multiple myeloma
Multiple Myeloma - Thalidomide Pharmion approved in Turkey for multiple myeloma
Multiple Sclerosis - Application submitted to European Medicines Agency for Antegren approval
Multiple Sclerosis - Bone marrow and CNS parenchymal iNOS have similar role in EAE
Multiple Sclerosis - Influence of HLA-DRB1 alleles on MS risk elucidated
Multiple Sclerosis - Integrin gene expression reduced in MS patients responding to IFN-beta treatment
Multiple Sclerosis - Peripheral blood microarrays provide valuable information on MS pathology
Multiple Sclerosis - Study: MS patients in personalized nurse program adhere to Betaseron treatment
Multiple Sclerosis - Trial tests diabetes drug in treatment of multiple sclerosis
Mutagenesis - Telomere length is maintained during early tumorigenesis
Mycobacterium - Multiple polymorphic loci used to type strains of Mycobacterium leprae
Myelodysplastic Syndromes - First component of Dacogen New Drug Application submitted to FDA
Nasopharyngeal Cancer - Nasopharyngeal carcinomas and Epstein-Barr virus reviewed
Nephrology - Cat scratch disease may lead to IgA nephritis
Neuroblastoma - Prognostic marker candidates for neuroblastoma identified
Neurodegeneration - Ubiquitin proteasome system involved in synaptic and axonal degeneration
Neuroscience - Exercise induces BDNF and synapsin I to separate hippocampal areas
Neuroscience - GPI-1046 attenuates ischemic brain damage in rats
Neuroscience - KA-induced neuronal death in immature OHCs region-specific and irreversible
Neuroscience - Lymphocyte dopamine receptor expression linked to persistent personality
Neuroscience - Peripheral olfactory ensheathing cells augment healing after spinal cord injury
Neuroscience - Proteins associate with tau mRNA and HuD protein in neuronal cells
Neurotoxicity - The advent of ifosfamide-related encephalopathy is unpredictable
Obesity - Recruitment complete for phase IIb AOD9604 obesity trial
Obesity Risk Factor - Occupational factors affect weight change among men in Danish cohort
Obesity Risk Factor - Socioeconomic status affects attitudes toward eating and weight
Obesity Surgery - Intestinal bypass syndrome presents as erythema nodosum
Obesity Therapy - Agents have different effects on behavioral satiety sequence in rats
Obesity Therapy - CCK-8 response changes after MC3/4-receptor blockade reported
Obesity Therapy - Capsaicin changes neuropeptide Y and cholecystokinin expression
Obesity and Diabetes - PCK1 is a candidate diabetes and obesity gene
Obesity and Diabetes - Short-term weight loss improved metabolic syndrome in overweight adults
Obstetrics - Intravenous nitroglycerin studied in preterm labor
Obstetrics - LMW heparin helps prevent venous thromboembolism in pregnancy
Oncogenesis - Novel PMS2 pseudogenes conceal the true genomics of pediatric cancer
Oncogenesis - The Niban gene is a candidate marker for renal cancer formation
Oncogenesis - Unique genes or gene products profile hepatocellular carcinomas
Oncology - Cancer therapy combining cisplatin and WR-2721 doesn't prolong patient response
Oncology - New models offer insight into the mechanics of thalidomide analogues
Oncology - XIAP is key modulator of TRAIL-mediated apoptosis in tumor cells
Oral Cancer - S100A4 expression prognostic indicator in invasive and metastatic oral SCCs
Oral Mucositis - L-glutamine formulation helps prevent, treat common chemotherapy side effect
Orthopedic Surgery - Nonstoichiometric hydroxyapatite granules effective in orthopedic surgery
Orthopedics - Periostin may play key role in early fracture healing
Osteoarthritis - Osteoarthritis patients report improved function in collagen hydrolysate study
Osteoporosis - Calcitonin reduces acute bone loss in patients with pertrochanteric fractures
Osteoporosis - Dietary fermented soybean may improve bone formation in premenopausal women
Osteoporosis - PAI complete for nasal-spray facility
Osteoporosis - Study finds dietary supplement increases bone mineral density
Outbreaks - Model for disease outbreaks in realistic urban networks developed
Ovarian Cancer - Gemcitabine yields favorable results vs. recurrent epithelial ovarian cancer
Ovarian Cancer - Generex prepares for trials in patients with Her-2/neu positive ovarian cancer
Ovarian Cancer - Tumor grade correlates with fluorodeoxyglucose uptake in ovarian cancer
Overactive Bladder - Company announces FDA approval of SANCTURA
Overactive Bladder - U.S. FDA approves Sanctura for treatment of overactive bladder
Pain Management - Vertebroplasty and kyphoplasty ameliorate cancer-derived fracture pain
Pain Therapy - Refinement of topical ENT-103 formulation begins
Pain Therapy - Report discusses effective ways to manage pain
Parkinson Disease - Specialty distributor provider chosen for Apokyn Parkinson therapy
Patents - China patent granted for Cyclosporin Neuroprotection
Patents - Company wins patent for Filled Canister apparatus related to bone repair
Patents - Company wins patents for genetically enhanced antigens for vaccine development
Patents - Gene therapy may be useful in cancer treatments
Patents - U.S. patent granted for asthma, allergy treatment
Pediatric Oncology - Neuroblastoma cells express Olf/EBF transcription factors
Peripheral Arterial Disease - Combination therapy to treat acute blocked peripheral arteries evaluated
Personnel - Alan Barber named chief financial officer at biotech firm
Personnel - Andrew P. Aromando named senior VP at biopharmaceutical firm
Personnel - Biopharmaceutical R&D company names vice president, business development
Personnel - Biopharmaceutical company appoints VP, preclinical and basic research
Personnel - Biopharmaceutical company names vice president, process development
Personnel - Biotechnology company announces appointment of new board member
Personnel - CRO appoints Lyon Gleich as director, medical affairs
Personnel - David Busam named VP of finance/administration, CFO at genomics firm
Personnel - David MacDonald promoted to president, CEO at biotech firm
Personnel - David S. Tierney named to board of directors at generic drug firm
Personnel - Development team formed for Axenohl silver dihydrogen citrate technology
Personnel - Donald W. Kufe elected to board of directors at oncology drug firm
Personnel - Dr. Michael Fons tapped as executive director, corporate development
Personnel - Dr. Wilfred Sylvain Nambei joins biotech as member of scientific committee
Personnel - Drug discovery company announces new board member
Personnel - Duu-Gong Wu joins drug development firm as senior director
Personnel - Edward Kenney named EVP, chief business officer of cancer therapeutics company
Personnel - Herbert Michael Pinedo joins board of oncology company
Personnel - John Cardis elected to board at cardiovascular disease company
Personnel - Joseph E. Smith elected to board of directors of pharmaceutical company
Personnel - Katherine High named president of gene therapy group
Personnel - Lead director of cancer therapy systems manufacturer passes away
Personnel - New member added to board of directors of biotech
Personnel - Nickel named business development, marketing VP at hematology firm
Personnel - Pharmaceutical company announces new appointments
Personnel - Pharmaceutical company appoints new vice president, clinical development
Personnel - Pharmaceutical firm announces changes to its board of directors
Personnel - Research products maker firm elects new member to board of directors
Personnel - Software/strategic services provider announces senior VP, business development
Personnel - Stem cell company announces management appointments
Pharmaceutical Companies - Drug company influence under microscope at annual AMA meeting
Pharmaceutical Drugs - Ann Arbor company closing in on production of eggs that carry drug ingredients
Pharmaceutical Drugs - FDA accuses maker of antiretroviral of misleading promotions
Pharmaceutical Sales - j-forceNET helps enhance pharmaceutical field force productivity in Japan
Pharmaceutical Settlement - Arkansas agencies get refunds from drug antitrust case
Pharmacogenomics - Patients in Japan, U.S. react differently to the same chemotherapy regimen
Pharmacology - HepDirect prodrugs deliver nucleoside-based therapy to the liver
Physical Fitness - BMI affects aerobic fitness during incremental exercise
Phytotherapy - The plant alkaloid sanguinarine suppresses angiogenesis
Pneumococcal Vaccine - Pneumococcal vaccine not cost-effective for all elderly adults
Pneumococcal Vaccine - Pneumococcal vaccine prevents pneumococcal disease but not pneumonia
Pneumococcal Vaccine - Responses to pneumococcal vaccine in IgA deficient patients studied
Polio Vaccine - Vaccine-derived poliovirus isolated from sewage in Estonia
Postoperative Ileus - Second portion of NDA submitted for Entereg
Practice Guidelines - ADA issues new advice to doctors on lowering diabetes-heart disease risks
Prion Disease - Cu(II) binding modes of mammalian normal prion protein examined
Prion Disease - Scrapie protein degraded by cysteine proteases in dendritic cells
Prion Disease - Tolerance to prion protein broken by prion protein peptides and ODN-CpG
Product Licensing - Hemosol completes agreements to license Cascade technology
Prostate Cancer - Common bone complications in advanced prostate cancer patients lead to increased medical costs
Prostate Cancer - Estrogen boosts memory in men with prostate cancer
Prostate Cancer - Estrogen patches lower cholesterol in men with prostate cancer
Prostate Cancer - Hormone treatment less effective for younger men with higher-grade tumors
Prostate Cancer - Marketing authorization granted for cancer products in Latin America
Prostate Cancer - Pill may stave off disease and ease pain
Prostate Cancer - Positive phase IIb data reported for ACAPODENE
Prostate Cancer - Tools needed to reliably report side effects in chemotherapy clinical trials
Proteomics - WNT signals encourage multiple myeloma cell proliferation
Pulmonary Medicine - Facial deposition of aerosol-delivered drugs characterized in children
Radiation Therapy - Researchers seek clues to healing radiation scars
Radiotherapy - Boron neutron capture therapy kills oral squamous cell carcinoma in mice
Receptor Studies - Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins
Receptor Studies - Hapten receptors bear selective delivery of imaging and therapeutic agents
Receptor Studies - Melanocortin-4 receptor agonist effect on energy homeostasis assessed
Receptor Studies - Photoaffinity scanning useful for mapping of the peptide receptor interfaces
Receptor Studies - Promoter of mouse melanin-concentrating hormone receptor 1 characterized
Receptor Studies - Transforming growth factor-beta superfamily of receptors reviewed
Reconstructive Surgery - Failed scalp replantation can induce dangerous psychological sequelae
Reconstructive Surgery - Free vascularized osteocutaneous fibular graft to tibia effective
Reconstructive Surgery - Immediate mandibular reconstruction serves oral cavity cancer patients well
Reconstructive Surgery - Novel dysvascular lower extremity reconstruction technique devised
Reconstructive Surgery - Prophylactic plating not cost-effective after radial osteocutaneous flap harvest
Rectal Cancer - Functional nuclear MRI is applied to in vivo anticancer research
Recurrent Gliomas - Phase II trial to study Cloretazine in adult patients with recurrent gliomas
Regulatory Issues - FDA rejects Illinois drug import pilot program
Renal Cell Carcinoma - Renal cancer tumor vessels express a member of the RGS superfamily
Renal Failure - AGE-modified materials may underlie prurigo in dialysis patients
Renal Failure - Rasburicase mitigates the nephropathic effects of tumor lysis syndrome
Reproductive Health - Human antisperm antibody response in SCID mice is complex
Reproductive Medicine - Microarray analysis reveals putative spermatogenesis genes
Reproductive Medicine - SerW3 cell assay useful for identification of reproductive toxins
Restenosis - Ultrasound-augmented nucleotide transfer harnesses neointimal growth
Rotavirus - Simple method for storage of rotavirus RNA in stool samples developed
SARS Vaccine - DNA vaccines target nucleocapsid protein of SARS coronavirus
Salmonella - Salmonella enterica Javiana infections linked to amphibian contact
Salmonella - Salmonella epitopes for CD8+-T-cell recognition identified
Schizophrenia - Drink can improve effectiveness of psychosis drugs, lessen side effects
Seizure Disorder - Inhibition of delayed induction of p38 protein kinase reduces neuronal loss
Sexually Transmitted Disease - Guide to sexually transmitted disease resources on Internet released
Sjogren Syndrome - Anti-cerebral mAChR antibodies involved in cognitive dysfunction
Skin Cancer - Evidence of increased apoptosis/reduced proliferation in tazarotene-treated BCC
Skin Cancer - Multicenter melanoma vaccine study demonstrates promising results
Skin Care - Kinerase product line to expand in 2004
Smallpox - Smallpox as biological weapon reviewed
Smoking Cessation - Generic Zyban launched under supply agreement
Smoking Cessation - Teva commences commercial launch of generic Zyban
Staphylococcal Vaccine - Opsonic antibodies target fibrinogen binding protein of Staphylococcus
Stem Cell Research - Stem cell transplants reactivate resolved hepatitis B virus infections
Stem-Cell Research - BCR-ABL has distinct biological effects in primary human hematopoietic cells
Stem-Cell Research - Fas may function as mediator of growth rather than death in neural stem cells
Stem-Cell Research - Glycine cleavage system abundantly expressed in embryonic neural stem cells
Stem-Cell Research - HSC mobilization-associated granulocytosis severely worsens acute renal failure
Stem-Cell Transplantation - AFLP accurately identifies Candida colonization in children undergoing SCT
Stem-Cell Transplantation - Allogeneic HSCT has favorable outcome in early CML in younger patients
Stem-Cell Transplantation - Functional evidence for single endodermal origin for thymic epithelium
Stem-Cell Transplantation - Lower doses of lymphocytes increase survival in myeloid leukemia
Stem-Cell Treatment - Fetal BM-derived Flk1+ CD34- stem cells are ideal as treatment source
Streptococcus - Mutant of response-regulator homologue from Streptococcus crystallized
Streptococcus - Residues 18-230 of PhtA protein from Streptococcus pneumoniae characterized
Stroke - U.K. study shows substantial reduction in stroke over past 20 years
Surgical Technology - Cyanoacrylate adhesive superior to sutures for microvascular anastomosis
Sydenham's Chorea - Chemokines linked to Sydenham's chorea pathogenesis identified
Testicular Cancer - Laparoscopic lymph node dissection is feasible for some testicular cancers
Thrombosis - New Arixtra indications: Acute deep venous thrombosis, acute pulmonary embolism
Toxicology - Trivalent arsenic stimulates proangiogenic signals
Transcriptional Regulation - Agents that activate NRIF3 coregulators would target breast cancer cells
Transduction - Electric field-induced molecular vibration forges DNA transfer
Transplant Medicine - Hepatitis C contributes to persistent ascites after liver transplantation
Transplant Medicine - Steatosis isn't linked to recurrent HCV in the year after liver transplantation
Tuberculosis Vaccine - Aerosolized IFN-gamma helpful for drug-resistant pulmonary tuberculosis
Tuberculosis Vaccine - Pantothenate auxotroph of M. tuberculosis protects guinea pigs
Tumor Suppression - Modified thrombospondin-2 cDNA transduction stops tumor growth and angiogenesis
Urinary Tract Infection - Ciprofloxacin therapy is efficacious for UTI treatment
Urothelial Cancer - Immunohistochemistry provides reliable determination of HER-2/neu status
Vaccine Development - Climate for funding of vaccine research reviewed
Varicella Vaccine - Varicella vaccine stabilizer without animal-derived components developed
Vector Development - Folate receptors ensure correct delivery of tumor-selective gene therapy
Vector Development - Hybrid LTR retroviruses seek and transfect tumor endothelial cells
Vector Development - PLL-modified silica nanoparticles transport antisense oligonucleotides
Vibrio - Lipase and lipase activator protein from Vibrio vulnificus CKM-1 cloned
Viral Genomics and Genetics - Purine ribonucleosides rely on unique relationships for hepatitis C inhibition
Virology - Adenoviruses D and E diagnosed by phylogeny-based classification method
Virology - Alternatively spliced soluble CARs inhibit coxsackievirus infection
Virology - Human T-cell leukemia virus type 1 displays preferential genomic integration
Virology - Molecular bases of Ad41 enteric tropism stem from its physicochemical properties
Virology - Priming deficient polymerase in HBV core particle allows for oligomer synthesis
Virology - Proteasome inhibition boosts viral replication in an HBX-dependent manner
Virology - Viral cocktails afford efficient gene transfer in animal models
Weight Loss - Weight loss decreased FT4 levels in experimental obese beagle dogs
West Nile Vaccine - Dow, federal lab to collaborate on plant-based vaccine for horses
West Nile Virus - Company receives approval for WNV protocol with Alferon N treatment
Wound Care - Chemokine receptor up-regulated after skin injury but unneeded for healing
Wrinkled Skin - Test results shows Dermagenetics reverses signs of aging
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