Central Nervous System

Regulation of myelin proteolipid protein gene expression reviewed

Published in Drug Week, July 2nd, 2004

Scientists review the regulation of myelin proteolipid protein gene expression in a recent issue of Cellular and Molecular Life Sciences.

According to a study from the United States, "The myelin proteolipid protein (PLP) gene (Plp) encodes the most abundant protein found in myelin from the central nervous system (CNS). Expression of the gene is regulated in a spatiotemporal manner with maximal levels of expression occurring in oligodendrocytes during the active myelination period of CNS development, although other cell types in the CNS as well as in the periphery can express the gene to a much lower degree."

"In oligodendrocytes, Plp gene...

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Source: Drug Week (2004-07-02)

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