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Microbiology

Biofilm testing may lead the way to effective antibiotic use in CF patients

Published in Drug Week, July 30th, 2004

Biofilm testing may lead the way to effective antibiotic use in cystic fibrosis (CF) patients.

"Pseudomonas aeruginosa is the predominant cause of chronic airway infection in CF. CF airway isolates are often tested for antibiotic susceptibility but are rarely eradicated by the antibiotics identified as potentially effective," reported researchers in the Journal of Clinical Microbiology.

According to S.M. Moskowitz and colleagues, "The growth state of P. aeruginosa in CF airways is probably different from that exhibited under conventional susceptibility testing conditions and may represent a bacterial biofilm."

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