Adverse Drug Events
Erythromycin combined with common drugs may increase cardiac death risk
Published in Drug Week, October 1st, 2004
Patients who took the antibiotic erythromycin with medications that inhibit CYP3A drug enzymes, such as certain calcium-channel blockers, certain antifungal drugs and some antidepressants, had a five-times greater risk of sudden death from cardiac causes than patients who did not take the drugs at the same time, according to a new study co-funded by U.S. Agency for Healthcare Research and Quality (AHRQ), U.S. Food and Drug Administration and U.S. National Institutes of Health.
Erythromycin is a commonly used antibiotic because it is considered to be inexpensive and very safe.
In the study, which was published in the September 9, 2004, issue of the...
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Source: Drug Week (2004-10-01)
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