Malaria Therapy
Molecular methods determine resistance to antimalarial drugs during epidemics
Published in Drug Week, October 8th, 2004
According to published research from Mali and the United States, "Plasmodium falciparum mutations pfcrt K76T and the dhfr/dhps 'quintuple mutant' are molecular markers of resistance to chloroquine and sulfadoxine-pyrimethamine, respectively. During an epidemic of P. falciparum malaria in an area of political unrest in northern Mali, where standard efficacy studies have been impossible, we measured the prevalence of these markers in a cross-sectional survey."
"In 80% of cases of...
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Source: Drug Week (2004-10-08)
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