Benign Prostatic Hyperplasia

Statistically significant positive phase II data reported on Cetrorelix

Published in Drug Week, November 5th, 2004

AEterna Zentaris, Inc., (AEZ; AEZS) announced statistically significant positive results from a randomized, double-blind, placebo-controlled phase II trial designed to evaluate different dosage regimens of a depot formulation of cetrorelix, a luteinizing hormone-releasing hormone (LHRH) antagonist, in 250 patients with symptomatic benign prostatic hyperplasia (BPH).

These new data demonstrate a dose-dependent, durable and statistically significant (p less than 0.001) improvement of clinical symptoms characteristic of BPH, including IPSS (International Prostate Symptom Score), at all dosages except the lowest, as well as an excellent safety and tolerability...

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Source: Drug Week (2004-11-05)

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