Published in Drug Week, November 5th, 2004
"The Arp2/3 complex and filamins play important roles in organization of actin cytoskeleton, and thus in cellular morphology and locomotion. We recently identified decreased expression of a gene for one of seven subunits of the Arp2/3 complex, the p41-Arc gene, and silencing of a filamin gene, the FLNc gene, in human gastric cancers.
"In this study, gene expressions of the seven subunits of the Arp2/3 complex, including p41-Arc, and their methylation statuses were analyzed in human gastric cancers," scientists in Japan report.
"Quantitative real-time RT-PCR...
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