Stem Cell Transplantation
Methotrexate associated with improved overall survival following ASCT
Published in Drug Week, November 5th, 2004
"We report long-term outcomes for allogeneic peripheral blood stem cell (PBSC) recipients, evaluating cumulative incidence (CI) of acute and chronic graft-versus-host disease (GVHD), after use of tacrolimus with or without minidose methotrexate for GVHD prophylaxis," wrote scientists in the journal Bone Marrow Transplantation.
"From April 1996 to April 1998, 97 adults underwent allogeneic PBSC transplantation. The first 49 received tacrolimus monotherapy as GVHD prophylaxis and the subsequent 48 received combination therapy. The median...
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Source: Drug Week (2004-11-05)
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