Drug Week

Cancer Therapy - Novel transplatinum drug ATZ interferes with topoisomerase I in cancer cells

Drug Development - Novel inhibitors of trypanosomal 6-phosphogluconate dehydrogenase designed

Drug Development - Tranilast ameliorates acute lung injury in guinea pigs

Melanoma - Data presented on peptide vaccine for melanoma

Pancreatic Cancer - CoFactor granted U.S. orphan drug status by the FDA

Prostate Cancer - Taxotere extends life of prostate cancer patients

AIDS/HIV Epidemiology - Temporal trends in HIV-1 epidemic in Russia reported

AIDS/HIV Vaccine - HDAC inhibitors reactivate HIV-1 expression in cellular reservoirs

AIDS/HIV Vaccine - Macaques infected with attenuated SIV remain resistant to challenge

Acute Coronary Syndrome - Myocardial angiogenesis is lower during cardiac ischemia in type 2 diabetics

Acute Liver Disease - Alpha-melanocyte-stimulating hormone gene transfer averts murine liver failure

Adenovirus Detection - Novel method detects and types adenoviruses directly from conjunctival scrapings

Adverse Drug Effects - ART drugs pose potential cancer hazard to exposed children

Allergy - Technologies company gets U.S. NIH contract to reduce dust mites in homes

Allergy Medicine - Antibiotics and fungal microbiota play roles in allergic responses

Allergy Medicine - Antibodies recognizing Bet v 1 and Humicola lanuginosa lipase isolated

Allergy Medicine - Azelastine appears effective for patients still symptomatic after fexofenadine

Allergy Medicine - Naringenin chalcone shows strong inhibition of histamine release

Alzheimer Disease - Biotech company announces results of Alzheimer study

Alzheimer Disease - Current status of Alzheimer disease genetics reviewed

Alzheimer Disease - Pharmaceutical company provides development update on Tau-directed therapeutics

Alzheimer Disease - Response to human and rodent A-beta peptide is species-specific

Anemia - Risks and benefits must be balanced when treating anemia in chronic HF

Angioedema - Fast-track designation announced for DX-88

Animal Studies - Marmosets with GB virus B infections model the pathogenesis of hepatitis C

Anthrax - Government to provide more funding for Anthim, an antianthrax drug

Anthrax Vaccine - Capsule of Bacillus anthracis behaves as type 2 antigen

Anti-Infectives - Antibody fusion protein coupled to glucose oxidase is bactericidal

Antibacterial Agents - Review focuses on three side effects of antibacterial macrolides

Antibiotics -  S. warneri ISK-1 gene cluster characterized

Antibiotics - Refined model for nisin pore formation proposed

Antimicrobial Resistance - Antimicrobial susceptibility of Streptococcus isolates reported

Antimicrobial Resistance - Bacterial resistance in the U.S. increasing

Antimicrobial Resistance - Integrons play minor roles in antibiotic resistance in surgical units

Antimicrobials - Baylor, biopharma to test an agent against deadly resistant bacteria

Antimicrobials - Human tear lipocalin exhibits antimicrobial activity

Antiretroviral Therapy - HAART changes hepatitis B and C viremia in patients coinfected with HIV

Antisense Technology - Select antisense molecules favor Duchenne muscular dystrophy exon 46 skipping

Antiviral Therapy - Adefovir curtails lamivudine-resistant mutants in woodchucks with hepatitis

Antiviral Therapy - Prolonged entecavir spawns new substitutions in drug-resistant hepatitis B

Apoptosis - Oxidative stress and caspase activation involved in paclitaxel-induced apoptosis

Apoptosis - c-Src kinase helps regulate TGF-beta 1-induced apoptosis

Arthritis - Consumers looking for Vioxx replacement may turn to systemic enzymes

Arthritis - European Union approves REMICADE for treatment of psoriatic arthritis

Arthritis - PPI treatment prescription levels not impacted by cox-2 therapy

Arthritis - Pharma company receives patent approval for arthritis treatment

Arthritis Therapy - Antibody to high-molecular weight kininogen shows promise in rat model

Assisted Reproduction - Drug protocols for IVF compared in breast cancer patients

Asthma Vaccine - Arthropod-derived histamine-binding protein prevents allergic asthma

Atherosclerosis - Collagen cross-linking linked to aortic wall stiffness in diabetes

Atherosclerosis - Glycation end products and vascular inflammation in diabetes reviewed

Atherosclerosis - Lipid inflammatory mediators in diabetic vascular disease reviewed

Atorvastatin - Atorvastatin may contribute to role of statins on endothelial function

Atrial Fibrillation - Review is designed to help general practitioners concerning atrial fibrillation

Autism Risk Factor - Mercury exposure not associated with autistic spectrum disorder

Autoimmunity - Retrogenic mice expand opportunities for exploring autoantigens

Awards - Biotech company recognized as a Top 20 Biotechnology Firm in New Jersey

Awards - Fuzeon awarded 2004 International Prix Galien for most innovative new medicine

Back Pain - Katy Clinic debuts breakthrough medical technology for treating back pain

Bacterial Conjunctivitis - Clinical sites activated for AzaSite trials in bacterial conjunctivitis

Behavior Intervention - Treatment fidelity is recommended as part of behavior intervention research

Bioengineering - Convergence of Markov chain Monte Carlo simulations assessed in pharmacokinetics

Biomolecular Research - Magnetic carriers used to detect, manipulate biomolecules

Blood Coagulation - FDA does not approve Exanta (ximelagatran)

Bordetella - Culture and PCR for Bordetella detection compared

Brain Stem Glioma - Brain tumor survivors visit research institute

Breast Cancer - Breast cancer imaging system delivered to Italy's National Tumor Institute

Breast Cancer - Chemopreventive properties of pomegranate extracts studied in murine model

Breast Cancer - Ninety-seven grants awarded to breast cancer scientists and researchers

Breast Cancer - Pharmaceutical company gains FDA clearance for cancer drug Provecta

Breast Cancer - Promoter methylation of PTEN gene is common molecular change in breast cancer

Breast Cancer - Study finds no link between tamoxifen and stroke

Breast Cancer Vaccine - Vaccine for prevention of HER2 mammary carcinomas under development

Business & Finance - Biotechnology company receives $2.7 million in financing

Business & Finance - Gene-identification company provides 2004 update

Business & Finance - Medical device company focusing on eye disorders secures interim financing

Business & Finance - Venture capital firm announces formation of private equity firm

Business Update - Amgen's profit surge on strong drug sales

Business Update - Analysis examines blood growth factors market

Business Update - Behavioral health company announces expansion at the Detroit Medical Center

Business Update - Bioservices company expands manufacturing capacity

Business Update - Biotech company reports increased demand for Multiferon in Mexico

Business Update - Biotech firm completes new headquarters and technical center

Business Update - Company sells Electronic Materials, Lancaster Synthesis, and SF-Chem

Business Update - Drug discovery company relocates corporate headquarters

Business Update - Fertility Monitor technology company retains AGORA Investor Relations

Business Update - Healthcare technologies company receives settlement from lawsuit

Business Update - Medication for canker sores now available in Oregon and Southwest Washington

Business Update - Metabilic drug company enacts Sarbanes-Oxley compliant initiative

Business Update - NETPHARMX, West-ward Pharmaceutical sign sales, marketing agreement for Glynanse

Business Update - New research facility opened in Boston

Business Update - Novartis reports 21% quarterly profit rise to US$1.55

Business Update - Pharma company announces expansion of SennaPrompt business

Business Update - Pharma company provides update on Neurontin legal developments, generic version

Business Update - Pharmaceutical company, P&G form alliance to market tablets for osteoporosis

Business Update - Strategic relationship formed to expedite, enhance quality of clinical trials

Business and Finance - Imaging company reports 2004 results and appoints new CEO

Caliciviruses - Human caliciviruses causes severe gastroenteritis in Peruvian children

Campylobacter - Thermophilic Campylobacter detected by real-time PCR hybridization probe assay

Cancer Growth Factors - Beta-defensins and VEGF-A nurture tumor neovascularization

Cancer Therapy - Discovery might improve design, effectiveness of anticancer drugs

Cancer Therapy - Epigenome manipulation turns off as many genes as it turns on

Cancer Therapy - FK228 gets fast-track designation for cutaneous T cell lymphoma

Cancer Therapy - Hyperforin keeps cancer invasion and metastasis in check in animal studies

Cancer Therapy - Imatinib sensitivity predicted by testing Wilms tumor gene expression

Cancer Therapy - PTEN deficiency predicts trastuzumab resistance in breast cancer patients

Cancer Therapy - Protein found to block anticancer drug access, reducing ability to reach tumors

Cancer Therapy - Toledo Clinic Inc., Detroit-based cancer institute announce alliance

Cancer Therapy - Tumor necrosis factor alpha sensitizes malignant cells to chemo drugs

Cancer Vaccine - CD4+CD25+ T cells are preferentially induced by vaccine vector

Cancer Vaccine - Cancer immunotherapy beyond current vaccines reviewed

Cancer Vaccine - GM-CSF vaccines impair immune response via myeloid suppressor cells

Cancer Vaccines - Nano-vaccines exhibit therapeutic and protective effects against tumors

Carcinogenesis - Lessons from DES use help researchers predict other perinatal cancer risks

Cardiology - Adenylyl cyclase type VI influences gene transcription in cardiac cells

Cardiology - Atrial and brain natriuretic peptide levels rise in the ischemic myocardium

Cardiology - Nuclear factor-kappa B decoy may treat cardiovascular and thrombotic diseases

Cardiology - Partnership restructures agreement to develop protein to aid in heart surgeries

Cardiomyopathy - Chemokine receptor DNA therapy prevents myocarditis-associated cardiac injury

Cardioprotection - Trans-resveratrol suppressed aortic atherosclerosis and reduced thrombosis

Cardioprotection - Vasodilator effect of red wine depends on EDHF in combination with NO

Cell Biology - DNA and histone synthesis are coordinated under normal and adverse conditions

Cell Biology - Histidine-rich glycoprotein tethers plasminogen to the cell surface

Central Nervous System - TIMP-3 gene transfer affords partial protection to cortical neurons in rats

Cerebrovascular Atherosclerosis -  Chlamydia pneumoniae not involved in severe cerebrovascular atherosclerosis

Cerebrovascular Disease - Global ischemia produces gene clusters that can index stress severity

Cervical Cancer - Evidence lacking for concomitant use of hydroxyurea plus radiotherapy

Chemosensitization - A new multicomponent drug delivery system sensitizes lung cancer to therapy

Childhood Obesity - More adolescent Kuwaiti boys than girls are obese

Chlamydia Vaccine - Novel recombinant multisubunit vaccine against Chlamydia developed

Chondrogenesis - ZNF470 may help regulate chondrogenesis-specific gene expression

Chorea - Valproic acid is an effective and safe drug for treatment of Sydenham chorea

Chronic Angina - MERLIN TIMI-36 study of Ranexa initiated

Chronic Fatigue Syndrome - Ampligen clinical trial data presented at international conference on CFS

Chronic Liver Disease - Hepatitis C virus NS5A and nuclear factor-kappa B generate liver injury

Chronic Myeloid Leukemia - BCR-ABL transcripts early predictors for hematological relapse in CML after HSCT

Clinical Trial - Survey evaluates willingness to allow children to participate in clinical trials

Collaborations - Agreement made to discontinue Peplin collaboration

Collaborations - Althea enters alliance to expedite genomic biomarker identification, application

Collaborations - Coriell Institute to install cell analysis system

Collaborations - GNI enters R&D drug-discovery collaboration

Collaborations - Healthcare services provider signs sales, distribution agreement with Ranbaxy

Collaborations - Partnership signed with Foundation for Ichthyosis

Collaborations - Partnership to allow hospital and university system to share resources

Collaborations - Protein therapeutics firm expands deal with Centocor

Collaborations - Transaction closed with BioOne Corporation

Colon Cancer Risk Factor - Program improves colorectal cancer prevention among African Americans

Contraception - IL-1, IL-6, and IL-8 predict toxicity of vaginal contraceptives

Cord Blood Transplantation - Patients over 45 years old without suitable BM donors may be candidates for CBT

Coronary Artery Bypass Grafting - Effects of enalapril, losartan, and/or IL-6 gene mutations determined

Coronary Artery Bypass Grafting - Propafenone has limited effect on post-CABG atrial fibrillation

Coronary Artery Disease - The proangiogenic effects of perlecan can treat ischemic diseases

Coronary Heart Disease - Biotechnology company to develop superantibody for coronary heart disease

Coronary Syndrome - Library will serve as a model for future substudy design

Coxsackievirus - Coxsackievirus replication and duration in intestinal cells described

Cryptococcus - Resistance to Cryptococcus dependent on maturation of NKT cells

Cushing Syndrome - GIPR regulatory genes are unlikely to underlie GIP-dependent Cushing syndrome

Cystic Fibrosis - Data presented on tobramycin powder for inhalation

Cystic Fibrosis - Positive phase II results reported for cystic fibrosis drug

DNA Research - DNA breaks adjacent to cytosines occur during Ig gene recombination

DNA Research - Incubation temperatures facilitate DNA hairpin structure reopening

Dendritic Cell Vaccine - Alpha-type-1 polarized dendritic cells optimize CTL-inducing activity

Dendritic Cells - SIRP- subset enriched in lymph dendritic cells from digestive tract

Dengue Vaccine - Encephalitis/dengue 4 virus chimera exhibits lack of neuro-invasiveness

Dengue Vaccine - The changing epidemiology of yellow fever and dengue reviewed

Dengue Virus - Dengue virus infections with varied serotypes occur sequentially/simultaneously

Dental Care - Mandatory fluoridation of drinking water up for debate

Depression - Future antidepressants may target the immune system

Depression - Program aims to reduce untreated depression

Depression - Second pivotal phase III clinical trial of CORLUX begins

Depression - Super-selective antidepressant effective, fast acting, better tolerated

Depression - U.S. FDA approves ANDAs for fluoxetine capsules, tablets

Dermatology - European patent awarded for sunscreen

Dermatology - In vitro human skin penetration of diethanolamine investigated

Dermatology - Multiple loci are responsible for causing Marie Unna hereditary hypotrichosis

Dermatology - Specialty pharmaceuticals company partners to market skin care products

Dermatology - Stat3 is required for the onset of epithelial carcinogenesis

Diabetes - Discovery companies file IND for DPP IV inhibitor to treat type II diabetes

Diabetes - Report calls for nurse-led interventions in insulin-resistant patients

Diabetes Genomics and Genetics - Lymphocyte-specific protein tyrosine kinase gene and diabetes analyzed

Diabetes Genomics and Genetics - UCP2 gene promoter polymorphism modulates lipids in diabetic patients

Diabetes Pathogenesis - Diabetes prevention mediated by CD1d-restricted nonclassical NKT cells

Diabetes Pathogenesis - Hepatic changes in acute phase of chemical-induced diabetes described

Diabetes Pathogenesis - High adiponectin level linked to lower risk of type 2 diabetes

Diabetes Pathogenesis - Inflammation in pancreatic islets in type 1 diabetes monitored

Diabetes Pathogenesis - Lipid accumulation and insulin responsiveness investigated

Diabetes Pathogenesis - Peptides from common pathogens can activate diabetogenic T cells

Diabetes Pathogenesis - Progression to islet destruction in transgenic model reviewed

Diabetes Pathogenesis - Syntaxin 4 transgenic mice have enhanced insulin-related glucose uptake

Diabetes Risk Factor - Diet composition and risk of type 2 diabetes reviewed

Diabetes Risk Factor - HLA class I molecules on T cells overexpressed in type 1 diabetes

Diabetes Risk Factor - Schizophrenia and diabetes reviewed

Diabetes Therapy - Abrogation of recurrent autoimmunity provides islet graft survival

Diabetes Therapy - Chard protects the liver of diabetic rats

Diabetes Therapy - IP receptors reduced in diabetic kidneys and mesangial cells

Diabetic Nephropathy - Early diabetes is model for testing regulation of juxtaglomerular NOS I

Diabetic Nephropathy - Familial clustering of diabetic nephropathy in type 1 diabetes studied

Diabetic Nephropathy - Human GFPT1 gene associated with diabetic nephropathy

Diabetic Nephropathy - PAI-1, uPA, and uPAR expression linked to mesangial expansion

Diabetic Nephropathy - Urinary pyrraline more directly affected than pentosidine by glycemia

Diabetic Neuropathy - QT indices regulated by autonomic nervous function in diabetic patients

Diabetic Retinopathy - The polyol pathway may play a role in human diabetic retinal disease

Diagnostics - Antitumor response visualized by fluorescent molecular tomography

Diagnostics - Bioassays company announces U.S. Army contract, new kinase Activity Assays

Diagnostics - Caribbean distributor orders second round of HIV diagnostic kits

Diagnostics - Invader assay quantifies covalently closed circular hepatitis B virus DNA

Diagnostics - Prevalence of Porphyromonas gingivalis associated with periodontal status

Diagnostics - Rapid diagnostic test kits used in Caribbean and China

Diagnostics - Surfactin-producing Bacillus subtilis rapidly detected and characterized by PCR

Diet and Nutrition - Benefits of fish oils for chronic heart failure reviewed

Diet and Nutrition - Dietary intake of saturated fats reviewed

Diet and Nutrition - Gamma-tocopherol is potential marker for nutrition-related risk

Diet and Nutrition - High-protein, low-carbohydrate diet reduces blood glucose in diabetes

Diet and Nutrition - Progress and prospects in nutritional research reviewed

Diet and Nutrition - Relations among eating behavior, diet, and regulation studied

Drug Abuse - Sister of girl who died with cocaine in system taken from mother

Drug Delivery - Liposomal cisplatin has reduced renal toxicity in animals

Drug Delivery - New tissue model may help reduce the number of animals needed for research

Drug Delivery - Novel drug-antidote strategy provides greater control of drug action

Drug Delivery - Pharma company successfully delivers Sumatriptan (Imitrex) via lingual spray

Drug Delivery - U.S. FDA approves prefilled, multidose, disposable growth hormone delivery system

Drug Delivery - Update provided on OraDisc technology

Drug Development -  Streblus asper volatile oil has anti-leukemia activity

Drug Development - Agreement expanded to assess drug compounds effects in cells

Drug Development - Beta cyclodextrin-chitosan adduct shows promise as bitter-taste blocker

Drug Development - Clinical trial for peptide-based diabetes drug with GLP-1 analogue initiated

Drug Development - Company: Analysis supports continued development of ENT-103

Drug Development - Generic drug developer receives U.S. FDA approval of sedative-reversing drug

Drug Development - Incadronate attenuates corticosteroid-induced osteopenia in rats

Drug Development - Mechanism of type II polyketide syntase polymerase could aid drug development

Drug Development - NIH agency awards $6 million contract for preclinical studies on drug addiction

Drug Development - New agents show promise for blocking tumor vascularity by targeting VEGF

Drug Development - Novel anti-TNF-alpha peptide-Fc fusion protein constructed

Drug Development - Novel synthetic epothilones show promising anticancer activity

Drug Development - Oral telbivudine generates virological response in chronic hepatitis B patients

Drug Development - Sugar-based drug development reviewed in scientific publication

Drug Discount Card - Card saves Medicare beneficiaries average of 22% on prescriptions

Drug Discovery - Drug discovery company to provide support to Serono

Drug Discovery - Screening services agreement signed for access to Transfluor technology

Drug Resistance - Oligonucleotide chips detect mutants in untreated patients with hepatitis B

Drug Resistance - Researchers push the envelope to overcome HIV/AIDS drug resistance

Dyslipidemia - Niaspan approved for marketing in France

Embryonic Stem Cell Research - Embryonic stem cells differentiated into a defined neuronal lineage

Embryonic Stem Cell Research - Human/rodent embryonic spinal cord SCs differentially generate oligodendrocytes

Encephalomyelitis - CD5 plays critical role in experimental autoimmune encephalomyelitis

Endocrinology - GnRH affects bone metabolism at the start of estradiol suppression in IVF

Endocrinology - Real-time PCR simultaneously analyzes numerous steroidogenic enzyme expressions

Endothelium - OUA selectively increased vascular reactivity to phenylephrine

Enzymology - Bmx distorts inflammatory processes in transgenic mice

Enzymology - Heme oxygenase-1 levels fall in livers with hepatitis C virus infection

Enzymology - Telomerase-immortalized endothelial cells are valuable for angiogenic research

Eosinophilic Meningitis - Outbreak of eosinophilic meningitis associated with raw vegetable juice

Epicardial Myocyte - Model is a useful tool for investigating mechanisms of arrhythmia

Epidemiology - Beauty treatments facilitate the spread of viral hepatitis in Italy

Epstein-Barr Virus - Immune responses against Epstein-Barr virus are varied

Erectile Dysfunction - Pharmacokinetics of erectogenic determined in diabetic rats

Erythropoiesis - Beta-galactosidase useful marker to detect definitive erythropoiesis after SCT

Eye Health - Pharma company donates funds to expand treatment for river blindness in Africa

Fibromyalgia - Study: Cymbalta provides sustained pain relief for women with fibromyalgia

Finance - $1.25 million milestone payment due to biosurgery firm

Finance - $9 Million funding round closed

Finance - Bioinformatics company secures EUR 2.25M growth financing

Finance - Biopharmaceutical company reports third quarter financial results

Finance - Biotech listed as one of Maryland's fastest-growing technology companies

Finance - Biotech reports third quarter revenue increase of 64%

Finance - Biotechnology company closes $50 million in series B financing

Finance - Business publication names Sacramento's fastest-growing company

Finance - Cancer vaccine maker reports loss of $0.54 per share

Finance - Cell-focused company execs adopt rule 10b5-1 prearranged stock sales plans

Finance - Device company receives $17.6M in series B funding

Finance - Device maker announces revenue performance for first 9 months

Finance - Diagnostics company announces record revenues in fiscal 2004

Finance - Diagnostics company completes reverse stock split

Finance - Enzyme-focused company announces $13.9 million private financing

Finance - Health care products manufacturer announces increase in third quarter sales

Finance - Integrated systems biology company secures $5 million financing

Finance - Market intelligence provider reports third quarter financial results

Finance - New biotech investment newsletter launched from San Francisco

Finance - New biotechnology investment conference slated for 2005

Finance - Oncology drug development company reports third quarter financial results

Finance - Pain-focused pharmaceutical company reports strong Q3 results

Finance - Pharmaceutical company reports third quarter 2004 financial results

Finance - Pharmaceutical completes $4.6 million private placement

Finance - Photodynamic therapy company receives $15 million line of credit

Finance - Provider of discovery and development services reports financial results

Finance - Stem cell banking firm reports 59% increase in revenues

Finance - Throat spray manufacturer announces sales estimates

Fungal Infections - Cancidas indications expand with FDA approval for empirical therapy

Gastric Cancer Vaccine - OK-432 after surgery for gastric cancer did not improve survival rate

Gastroenterology - Pharmaceutical company announces positive results of Balsalazide study

Gene Delivery - Physical properties characterize the success of lipoplexes

Gene Expression - Transgene expression endures under the right conditions

Gene Linkage - Linkage studies refine the association of MAPT and Parkinson disease

Gene Mapping - Marker studies grow closer to identifying a gene for the MRX84 disorder

Gene Mutation - Mutation hotspots in p53 gene depend on tumor type and cell growth conditions

Generalized Anxiety Disorder - New data suggest Cipralex is superior to Paxil for GAD

Generic Drugs - Generics association: Flu vaccine shortage highlights need for biogenerics

Generic Drugs - Generics company announces final approval and launch of anticonvulsant drug

Generic Drugs - Report: Drug companies invent new strategies to fend off generic competitors

Genomics - Genomics company and GlaxoSmithKline sign agreement for genome scanning project

Geriatrics - Alterations in MCP-1 may influence the pathology of Alzheimer disease

Gingivitis - Long-term cyclosporin A exposure suppresses cathepsin-B/-L in gingival cells

Gum Disease - Laser gum-disease protocol gains FDA clearance

Gynecological Oncology - The enzyme inhibitor zoledronic acid thwarts cervical carcinogenesis

Gynecology - Overexpressed p53 correlates with the aggressiveness of endometrial cancer

HIV/AIDS Activation - TRAF-specific inhibitory peptides may be used to regulate HIV activation

HIV/AIDS Diagnostics - Cobas Amplicor HIV Monitor 1.5 test modified to measure proviral DNA in PBMCs

HIV/AIDS Drug Resistance - Multidrug-resistance in primary HIV infection leads to superinfection

HIV/AIDS Drug Resistance - Primary drug resistance persists in recently HIV-1 infected adults

HIV/AIDS Healthcare - World Health Assembly identifies HIV/AIDS treatment initiative goals for Malawi

HIV/AIDS Immunology - Immune reconstitution after HAART due to decreased immune activation in children

HIV/AIDS Immunology - T cell subset reference ranges vary among HIV/AIDS patient groups in India

HIV/AIDS Pathogenesis - Inducible iNOS CCTTT-repeat polymorphism not associated with HIV pathogenesis

HIV/AIDS Quality of Life - HIV/AIDS effect on life expectancy in the United States updated

HIV/AIDS Research - Novel CCR5 mutation affects HIV co-receptor immunoreactivity/fusogenic property

HIV/AIDS Research - Structure of HIV-1 genomic RNA in gp120 gene determines a recombination hot spot

HIV/AIDS Research - Tat expression influence on x(c)- independent of cellular status of glutathione

HIV/AIDS Research - Two binding modes for HIV-1 reverse transcriptase suggested

HIV/AIDS Therapy - Imperatorin inhibits HIV-1 replication through Sp1-dependent pathway

HIV/AIDS Therapy - L-chicoric acid inhibits HIV-1 integration

HIV/AIDS Therapy - Statins inhibit HIV-1 infection by down-regulating Rho activity

HIV/AIDS-Associated Brain Injury - HIV-associated brain injury leads to less efficiency in normal attention network

HIV/AIDS-Related Arthritis - Inflammatory arthritis in HIV infection not a form of spondyloarthropathy

HIV/AIDS-Related Conditions - Fat fractions/spectral T-2 values in vertebral BM differ in HIV/non-HIV patients

HIV/AIDS-Related Dementia - Sphingolipid and sterol metabolism in HIV dementia dysregulated by ApoE4

HIV/AIDS-Related Kaposi Sarcoma - HAART plus pegylated liposomal doxorubicin effective in Kaposi sarcoma

Head and Neck Cancer - Estrogen metabolite enhances protein transduction therapy in oral cancer cells

Healthcare Coverage - Insurance survey shows increase in consumer-driven health products

Heart Disease Risk Factor - Fatty acid oxidation increased in insulin-resistant ob/ob mouse hearts

Helicobacter -  Helicobacter pylori infection of primary gastric cells investigated

Helicobacter - IgA better than IgG in Helicobacter-related urease activity inhibition

Helicobacter - Noninvasive method for monitoring H. pylori infection developed

Helicobacter Vaccine - Immunity against H. pylori impaired in IL-18-deficient mice

Hematology - COX II inhibitor spares platelets when pegylated interferon is used for HCV

Hepatitis B Therapy - Application submitted in U.S., Europe to market entecavir

Hepatitis C Virus Therapy - Combination therapy for HCV alters the profiles of maturing dendritic cells

Herpes - Investigational trial completed for treatment of herpes

Herpesvirus - DNA vaccine trial initiated for treatment of herpes simplex type 2

Herpesvirus - HHV-6 antigenemia associated with GVHD following allogeneic stem cell transplant

Herpesvirus - Mutations in herpes glycoprotein prevent cell entry via nectins

Herpesvirus - Risk reduction counseling decreases incidence of herpes infection

Human Genome - NIH grant for ultra-miniaturized technology to sequence whole human genomes

Hypertension - All dihydropyridine CCBs licensed for once-daily administration are equivalent

Hypertension - Amlodipine and HRT are good partners for lowering blood pressure

Hypertension - Chronic nitric oxide synthase inhibition influences cardiac remodeling

Hypertension - Study reports patent expiry of Pfizer antihypertensive will erode drug market

Idiopathic Pneumonia Syndrome - Pulmonary histopathology after BMT accompanied by endothelial cell apoptosis

Immunology - A new hepatocyte-specific autoantibody may be linked to autoimmune hepatitis

Immunology - CD4+ T cells needed to maintain memory CD8+ T cells after infection

Immunology - Co-infection affects outcome of Helicobacter and Toxoplasma infections

Immunology - Dendritic cells are functionally impaired in patients with chronic hepatitis B