Published in Drug Week, December 3rd, 2004
According to published research from Scotland, "Phenobarbital (PB) is the most widely used antiepileptic drug (AED) in the developing world and remains a popular choice in many industrialized countries. Meta-analyses of randomized controlled trials suggest that few differences in efficacy exist between PB and other established AEDs, but its possible deleterious cognitive and behavioral side effects remain a concern in the developed world."
P. Kwan and M.J. Brodie wrote, "In contrast, high degrees of efficacy and tolerability in everyday clinical use have...
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