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Influenza Virus

Transmissibility of 1918 pandemic influenza reviewed

Published in Drug Week, February 11th, 2005

Investigators review the transmissibility of the 1918 pandemic influenza in a recent issue of Nature.

According to a study from the United States, "The 1918 influenza pandemic killed 20 to 40 million people worldwide, and is seen as a worst-case scenario for pandemic planning. Like other pandemic influenza strains, the 1918 A/H1N1 strain spread extremely rapidly. A measure of transmissibility and of the stringency of control measures required to stop an epidemic is the reproductive number, which is the number of secondary cases produced by each primary case. Here we obtained an estimate of the reproductive number for 1918 influenza by fitting a deterministic SEIR...

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