Susan Hasty, Publisher
Table of Contents . . . March 11th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Alzheimer Disease - Phenserine fails to achieve significant efficacy in phase III trial
Bioterrorism - Biotechnology company working on vaccine development against bioterror agents
Drug Development - Anamantle HC cream launched as hemorrhoid therapy
Drug Development - Pharmacogenomics predicted to have major impact in future drug development
Hormone Replacement Therapy - HRT controversy raises drug safety issues
Acetylcholine Receptors - Alpha-conotoxins studied, distinct nicotinic acetylcholine receptor sites shown
Acinetobacter - Acinetobacter isolates show decrease antibiotic susceptibility over 10+ year
Addiction Medicine - Research identifies proteins crucial to brain's information superhighway
Age-Related Macular Degeneration - Company announces reimbursement terms for Macugen
Agricultural Pest - B. latifrons identified by rapid real-time PCR using SYBR Green chemistry
Allergy Medicine - DC activation by LPS down-regulates birch allergen-induced Th2 differentiation
Allergy Medicine - Immunotherapy in age of anti-IgE reviewed
Allergy Medicine - New information in pediatric allergology reviewed
Allergy and Immunology - Anhydrase II antibody is not a prognostic marker of autoimmune pancreatitis
Allergy and Immunology - Circulating dendritic cells fall short in hepatitis B virus-infected humans
Allergy and Immunology - Interleukin-10 gene therapy protects islet grafts after transplantation
Alzheimer Disease - Pharmac companies collaborate on treatments for neurodegenerative diseases
Alzheimer Disease - Rat brain proteins may mediate neuroprotective actions of grape seed extract
Amyloid Formation - Amyloid formation analyzed, thermodynamic parameters directly measured
Andropause - Company begins phase I clinical trial for its second SARM, ostarine
Anesthesia - Maximum recommended doses of local anesthetics aren't evidence based
Angiology - Celecoxib uses multiple signaling mechanisms to suppress neovascularization
Angiology - Findings in angiology provide new insights
Angioplasty - Automated system suitable for monitoring response to anti-platelet therapy
Anthrax Vaccine - Rabbit and primate models of toxin-targeting anthrax vaccines reviewed
Anti-Infectives - Grapefruit juice enhances antischistosomal effects of artemether
Antibacterial Agents - Positive results reported for Microbisol
Antibiotic Resistance - Penicillin resistance of Streptococcus pneumoniae in Spain decreasing
Antimicrobials - Production of an antifungal molecule by B. licheniformis BC98 optimized
Apoptosis - Histatin analyzed, inhibition of apoptosis in human gingival fibroblasts shown
Arthritis - U.S. FDA opens hearing on arthritis drug safety
Asthma - African-Americans may need more medication to control asthma
Asthma - Montelukast significantly reduces asthma exacerbations in young children
Asthma - Published study finds mother's asthma or allergies may increase risk of autism
Atherosclerosis - Carotid atherosclerosis incidence high in diabetes plus nephropathy
Atherosclerosis - Trial of RUS 3108 begin in Ireland
Attention Deficit Hyperactivity Disorder - Pharmaceutical company provides update on clinical trials and pipeline
Bacteriology - Antibacterial effect of wine may be a synergy of organic acids, ethanol, low pH
Bacteriology - Melittin analyzed, hemolytic role of leucine zipper motif revealed
Beta-Blockers - Increasing the use of beta-blockers has potential for important clinical impact
Biomedical Engineering - Nanobiohybrids implement fluorescent protein transfection
Biomedicine - Data mining in biomedicine realized by using digital and molecular libraries
Biotechnology - Novel immunoassays for biochanin A developed
Biotechnology - Novel method enables controlled generation of liquid crystal defects
Bone Repair - Heparan sulfate mimetic augments the healing of craniotomy defects
Bovine Thyroglobulin - Bovine thyroglobulin studied, nature of multimerization clarified
Breast Cancer - Earlier fulvestrant use in heavily pretreated older women may be more effective
Breast Cancer - Hypothyroidism associated with reduced breast cancer risk
Breast Cancer - Recent findings in breast cancer provide new insights
Brucella - Genetic bases of rifampin resistance in Brucella reported
Business & Finance - Antibiotics-focused biopharmaceutical company announces corporate restructuring
Business & Finance - Biopharma company reports second quarter results
Business & Finance - Biotechnology company announces year end results, progress
Business & Finance - Company releases financial results, provides summary of R&D efforts
Business & Finance - Cytoskeleton-focused company reports $2.2M Q4 revenues, provides oncology update
Business & Finance - Emtriva maker reports increased Q4 and full-year revenues
Business & Finance - Health care products company announces financial results, new hire
Business & Finance - Pharmaceutical company announces agreement to manufacture Raloxifene tablets
Business & Finance - Pharmaceutical company announces first quarter ended December 31, 2004, results
Business & Finance - Pharmaceutical company makes strategic investment in Triad Pharmaceuticals, Inc.
Business & Finance - Pharmaceutical firm reports loss of $0.14 per share, pipeline update
Business & Finance - Pharmaceutical firm reports on alliance, financial results
Business & Finance - TF decoy-technology company reports improved revenues, lower losses in 2004
Business & Finance - Thermal solutions company secures funding to develop thermoelectric devices
Business Update - Banta Corp. sells its healthcare products business
Business Update - Biomedical company's distribution network expands in China
Business Update - Biomedical foods company receives large purchase order
Business Update - Biopharma company and EnVivo sign HDAC collaboration agreement
Business Update - Biopharmaceutical company signs long-term supply agreement
Business Update - Carni Q-Gel Forte receives U.S. Pharmacopeia's verification approval
Business Update - Cobra extends its agreement to provide long-term manufacture of REOLYSIN
Business Update - Company applies for membership in the Cryogenic Society of America
Business Update - Dermatology firm acquires U.S., Canadian rights to Solage
Business Update - Dermatology firm announces stock sale
Business Update - ExonHit launches SpliceArray Service with GPCR and ion channel microarrays
Business Update - German biotech company transfers lab automation business to AVISO GmbH
Business Update - Glaxo makes $1.0 million payment, starts phase 2 studies of oral platelet drug
Business Update - Maker of OTC migraine remedy recaps achievements of past 12 months
Business Update - Model for Bio-Healthcare Park unveiled at ceremony for Pharmaplaz in Ireland
Business Update - Oncology company moves HQ and R&D operations to San Diego facility
Business Update - Pharma-focused IT company announces relocation of worldwide headquarters
Business Update - Pharmaceutical company expands animal health business with acquisition
Business Update - Pharmaceutical company release liquid iron supplement
Business Update - Profit rises 12% at pharmacy-benefits manager MeD.C.o Health
Business Update - Supply company created to develop and market clinically tested products
Business Update - Survey shows pharmaceutical firms must innovate smarter and faster
Business Update - Technology company signs supply agreement with Roche Molecular Systems
Business Update - Technology consulting and engineering firm joins MDL Isentris Alliance
Business Update - e-Pharmaceutical marketing company recognized as eDetailing vendor market leader
Calcium Channels - Calcium channels studied, role of voltage gating in aldosterone secretion found
Cancer Research - Cysteine cathepsins allowed the invasion of AdoMetDC-transformed rodent cells
Cancer Research - Gleevec-resistant gastrointestinal stromal tumors therapy shows positive results
Cancer Research - Trial to study oral spray to reduce chemotherapy-induced nausea
Cancer Therapy - 'T-body' approach may have therapeutic potential in disseminated prostate cancer
Cancer Therapy - BCL-2 inhibition sensitizes malignant cells to cancer immunotherapy
Cancer Therapy - Common virus becomes a new target for cancer treatment
Cancer Therapy - Company to discontinue further development of Pegamotecan
Cancer Therapy - Doxorubicin nano-aggregates stabilized by DOX-PEG-FOL conjugates
Cancer Therapy - EPO induces cancer cell resistance to ionizing radiation and cisplatin
Cancer Therapy - Genomics companies partner to investigate role of cancer genes
Cancer Therapy - New data illuminates research in cancer therapy
Cancer Therapy - Normalization windows sensitize cancer cells to therapy
Cancer Therapy - Particle therapy technology to treat tumors to be installed at Heidelberg center
Cancer Therapy - Pharmaceutical company receives PDUFA dates for chemo drug, reports finances
Cancer Therapy - Phase I human clinical trial with 1D09C3 begins
Cancer Therapy - Photodynamic therapy successfully treated feline skin cancer
Cancer Therapy - Recent findings illuminate research in cancer therapy
Cancer Therapy - Researchers describe how tumors acquire resistance to kinase inhibitors
Cancer Therapy - Resveratrol displayed chemopreventive effects
Cancer Therapy - Silibinin limits doxorubicin-induced toxicity in murine tumor models
Cancer Therapy - ZD6474 arrests the growth of gefitinib-sensitive tumors
Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge
Cancer Vaccines - Studies advance knowledge in cancer vaccines research
Canine Distemper Virus - Hemagglutinin gene of canine distemper viruses analyzed
Cardiology - CD28 peptidemimic prolongs survival of cardiac allografts
Cardiology - Cost of thorough QT/QTc study may be reduced to 25-30% of the cost of simple ECG
Cardiology - Defibrillator manufacturer introduces new AED for professional rescuers
Cardiology - Diagnosis of antiphospholipid syndrome is difficult in anticoagulated patients
Cardiology - Endothelin-1 enables cardiac cells to tolerate hypoxia
Cardiology - Recent findings in cardiology described
Cardiology - Simvastatin boosts the efficacy of proangiogenic gene therapy
Cardiology - Studies add new findings to cardiology body of knowledge
Cardiology - Study examined behavior of inositol 1,4,5-trisphosphate in heart and lung tissue
Cardiology - Study on stroke prevention in atrial fibrillation patients published in JAMA
Cardiovascular Disease - Domain antibody company joins European effort to discover new CVD treatments
Cardiovascular Disease Therapy - Novel EVA drug matrix enhances transdermal atenolol delivery
Cardiovascular Research - ETB receptors may have a role in regulating development of the ETA subtype
Cardiovascular Research - Study investigated effects of amiodarone on the vascular endothelin system
Cell Biology - Novel interferometry assay enables nanoscale molecular interaction analysis
Cell Biology - Scientists share new insights into muscle growth regulation
Cell Signaling - Inhibition of gallbladder contractility, role of ions clarified
Cholera Outbreak - Two fowl cholera outbreaks 8-years apart caused by same P. multocida clone
Chronic Hepatitis C - Triple combination therapy benefits previous hepatitis C non-responders
Chronic Liver Disease - Metallothionein gene therapy reverses liver fibrosis in mice
Chronic Liver Disease - Nonalcoholic fatty liver disease affects patients with hepatitis C adversely
Chronic Liver Disease - The incidence of nonalcoholic steatohepatitis is expected to rise in Japan
Chronic Liver Disease - Various factors influence chronic hepatitis C-related fibrosis progression
Chronic Pain - Dosing of phase I pharmacokinetic study for sufentanil patch product completed
Chronic Renal Failure - ET-1 production may be responsible for susceptibility to chronic renal failure
Clinical Trials - Company to start percutaneous heart valve clinical trial in U.S
Clinical Trials - Market research company releases study on per patient clinical trials cost
Clinical Trials - Results from ZEGERID Chewable Tablet trials announced
Clinical Trials - Results of phase 2 clinical trials with recombinant human thrombin announced
Clinical Trials - U.S. FDA requests additional information regarding company's clinical trials
Cloning - pTOC-T vector constructed by using GST-ParE toxin for direct cloning
Clostridium Vaccine - Immunization against Clostridium diarrhea and colitis reviewed
Collaborations - Agreement completed for rights to vaccines
Collaborations - Agreement signed for dopamine stabilizer technology
Collaborations - Agreement with U.K. Medical Research Council extended
Collaborations - Companies form alliance to provide services to clients
Collaborations - Companies sign alliance program for protein kinase target
Collaborations - Contract with Sunkist expanded to Hong Kong and Taiwan
Collaborations - Deal entered with Cilag for antibiotic
Collaborations - Hot mouse technology used for diabetes, obesity therapies
Collaborations - License agreement signed for novel diagnostic targets
Collaborations - Partnership formed so hospital can conduct clinical trials for drug company
Collaborations - Pharma firm announces licensing deal for transmucosal film technology
Collaborations - Pharmaceutical deal expanded for multiple developmental projects
Collaborations - Relationship with Eli Lilly renewed
Collaborations - Research collaboration agreement signed
Collaborations - Supply agreement signed for sale of needle-free systems
Collaborations - Tripos chosen as strategic chemistry partner in drug discovery
Colon Cancer - Ritonavir may curb colon carcinogenesis via apoptosis/inflammatory modulation
Colon Cancer - Studies describe new findings in colon cancer research
Colorectal Cancer - Drug company receives U.S. FDA approval for new Eloxatin formulation
Complementary & Alternative Medicine - Pu-erh tea analyzed, influence on physiological damage clarified
Complementary & Alternative Medicine - Radix astragali astragaloside IV studied, properties clarified
Complementary and Alternative Medicine - Psychoactive effects of guarana and ginseng evaluated
Compstatin - Compstatin analyzed, thermodynamics of interaction with complement revealed
Congestive Heart Failure - Thousands of heart failure deaths in U.K. are preventable, survey shows
Constipation - DFA III provided relief to patients with chronic constipation
Coronary Angioplasty - Combination of FXa and GPIIb/IIIa inhibitors safe and effective in mice
Coronary Heart Disease - Studies have investigated genetic variants and response to statin therapy
Coronary Stenting - Clopidogrel responsiveness after stent implantation highly variable
Creutzfeldt-Jakob Disease - Pharma company finds way to remove prions that cause mad cow in humans
Cystic Fibrosis - Burkholderia cepacia increases mortality in cystic fibrosis
Cystic Fibrosis - CFTR biogenic intermediate studied, conditions of accumulation clarified
Cytomegalovirus Vaccines - Findings describe new data in cytomegalovirus vaccines research
DNA - DNA ligase analyzed, influence of replicative clamp loader revealed
Dendritic - DC-SIGN tetramers essential for high affinity interactions with HIV
Dendritic Cell Vaccine - Apoptosis of monocytes influences yield of dendritic cells
Dendritic Cell Vaccine - Method to monitor T cells after dendritic cell vaccination developed
Dendritic Cell Vaccine - Transcriptional regulation of dectin-2 promoter investigated
Dengue Fever - New findings in dengue fever described
Dengue Outbreak - Integrated therapeutic/public health response controls dengue outbreak
Dermatology - Adenovirus-based gene transfer prevents cancer in xeroderma pigmentosum models
Dermatology - Desmoglein 4 gene mutations correlate with hypotrichosis in lanceolate models
Dermatology - The loricrin gene is not involved in psoriasis susceptibility
Diabetes - Community-based diabetes plan of action introduced
Diabetes Complications - Amyloid peptide channels play role in diabetes complications
Diabetes Complications - Medications prevent diabetic kidney damage in rats
Diabetes Genomics and Genetics - Idd1 and Idd3 needed for development of type 1 diabetes
Diabetes Genomics and Genetics - Prevention of type 2 diabetes from viewpoint of genetics presented
Diabetes Genomics and Genetics - Risk of type 1 diabetes predicted from polymorphisms in candidate genes
Diabetes Pathogenesis - ATP synthase functions as fuel sensor in pancreatic beta cells
Diabetes Pathogenesis - Cytokines activate caspase-3 in insulinoma cells of diabetes-prone mice
Diabetes Pathogenesis - Findings advance knowledge in diabetes pathogenesis research
Diabetes Pathogenesis - IA-2 antibodies linked to increased risk of type 1 diabetes
Diabetes Pathogenesis - Impaired response to glucose load linked to low glucose storage
Diabetes Pathogenesis - Insulin secretion capacity in development of type 2 diabetes examined
Diabetes Pathogenesis - Protein kinase activation increases insulin secretion
Diabetes Pathogenesis - Recent findings in diabetes pathogenesis described
Diabetes Pathogenesis - Research add new data to diabetes pathogenesis body of knowledge
Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights
Diabetes Pathogenesis - Researchers describe findings in diabetes pathogenesis studies
Diabetes Pathogenesis - Researchers detail new studies and findings in the area of diabetes pathogenesis
Diabetes Pathogenesis - Studies advance knowledge in diabetes pathogenesis research
Diabetes Risk Factors - Breast-feeding protects glucose metabolism in young adult women
Diabetes Risk Factors - Hepatitis C virus infection triggers diabetes in liver graft recipients
Diabetes Surgery - Islet transplantation is realistic for type 1 diabetes treatment
Diabetes Therapy - Commelina communis exhibits anti-hyperglycemic activity
Diabetes Therapy - Beta-cell cyclic adenosine monophosphate targeted diabetes therapy
Diabetes Therapy - Metformin not oxidized by free radicals in vivo
Diabetes Therapy - Molecular therapeutic target for type 2 diabetes reported
Diabetes Therapy - Preventing type 1 diabetes from viewpoint of beta-cell damage outlined
Diabetes Therapy - Sulfonylurea and non-sulfonylurea hypoglycemic agents reviewed
Diabetes Therapy - Sweet steviol glycoside derivatives effective against hyperglycemia
Diabetes Therapy - Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice
Diabetic Cardiomyopathy - Coronary artery surgery for diabetic patients outlined
Diabetic Foot Ulcers - U.S. FDA gives clearance to initiate diabetic foot ulcer trial
Diabetic Nephropathy - Advanced glycation end products important in diabetes complications
Diabetic Nephropathy - Erythropoietin inhibits endothelial cell apoptosis induced by glucose
Diabetic Nephropathy - Hypertriglyceridemia implicated in diabetic nephropathy
Diabetic Nephropathy - Researchers report details of new studies and findings in the area of diabetic nephropathy
Diabetic Neuropathy - Adipocytokines contribute to diabetic neuropathy
Diabetic Neuropathy - Brain metabolic alterations induced by hyperglycemia in type 1 diabetes
Diabetic Neuropathy - Diabetes induces expression of activating transcription factor 3
Diabetic Neuropathy - Kinin B-1 receptors expressed in spinal cord of diabetic rats
Diabetic Neuropathy - Methods to slow progression of diabetic neuropathy reviewed
Diabetic Neuropathy - Neural redox stress in type 2 diabetes and neuropathy reviewed
Diabetic Neuropathy - Reports advance knowledge in diabetic neuropathy research
Diabetic Neuropathy - Studies advance knowledge in diabetic neuropathy research
Diagnostics - LightCycler polymerase chain reaction can diagnose fungal infections
Diagnostics - Method to monitor zinc and calcium secretion from islet cells developed
Diagnostics - Researchers' data advance diagnostics research
Diagnostics - Stool-based DNA test is preferred over FOBT, colonoscopy for colorectal cancer
Diagnostics - Studies add new findings to diagnostics body of knowledge
Diagnostics - Transcriptional-based screens detect endothelial cell gene products
Diarrhea Vaccine - Antibody binding linked to activity of F4 fimbrial adhesin FaeG
Diet & Nutrition - New survey reveals challenges women face in consistent multi-vitamin routine
Diet & Nutrition - USU and HJF sign agreement for development of radiation protection compounds
Diet and Nutrition - Dietary fatty acids have dissimilar effects on genes in the rodent liver
Diet and Nutrition - Rice bran extract prevents elevation of plasma peroxylipid in diabetes
Disease Associations - Alpha-synuclein studied, influence of C-terminal domain on aggregation revealed
Disease Associations - Huntingtin interacting protein-1 related gene variants link to bipolar disorder
Disease Transmission - In Uganda, poverty is affecting AZT use among mothers
Drug Abuse - Methamphetamine-contaminated homes spur new push for federal research
Drug Abuse - Wyoming Senate panel approves meth bills
Drug Abuse - Zoners approve methadone dispensing on Bay Street in Vermont
Drug Delivery - Drug-delivery company retains OTC Financial Network
Drug Delivery - Introns are required for prolonged apolipoprotein A-I transfection
Drug Delivery - Lipid sponge phase as a transdermal drug delivery vehicle discussed
Drug Delivery - Market research company announces report on CNS diseases and drug delivery
Drug Delivery - New oral drug delivery technology improves effectiveness
Drug Delivery - Non-viral vectors make efficient antisense oligonucleotide delivery systems
Drug Delivery - Pharmaceutical company begins study of lingual spray of antiemetic agent
Drug Delivery - Pharmaceutical company offers ozone-friendly inhalation aerosol
Drug Delivery - Reports describe recent advances in drug delivery research
Drug Delivery - SLNs improved oral bioavailability of poorly soluble drugs
Drug Detection - Scientists make step forward in identifying drug doping
Drug Development - Additional ACT 1 clinical results reported
Drug Development - An oncolytic DNA-alkylating drug for treatment of solid tumors shows promise
Drug Development - Anti-IL-13 monoclonal antibody shows promise for asthma treatment
Drug Development - Bioactive peptide conjugates characterized using thioether linkages
Drug Development - Biopharmaceutical company announces new drug application
Drug Development - Blockbuster drugs with expiring patents gain new hope
Drug Development - Clinical trials for Emezine completed
Drug Development - Companies announce translational medicine strategic alliance
Drug Development - Diquafosol fails to demonstrate significant improvement in dry eye
Drug Development - Drug development company announces approval of new drug application
Drug Development - Emodepside has novel mode of anthelmintic activity
Drug Development - Functional interaction of CYP3A4 and P-glycoprotein warrants further research
Drug Development - International trial of two anti-HIV microbicides begins
Drug Development - Intrapleural gene therapy may cure human alpha1-antitrypsin deficiency
Drug Development - New generation reagent dispenser launched
Drug Development - Nutritional supplements marketer to introduce new product
Drug Development - Onconase clinical program expanded
Drug Development - Phenylalanine aminomutase analyzed and cloned
Drug Development - Protein microarray chips unearth new peptides with therapeutic potential
Drug Development - Regadenoson shows promise for myocardial perfusion imaging
Drug Development - Report details pharmaceutical brand team's road to success
Drug Development - Safety profile of naproxen detailed in U.S. FDA briefing document
Drug Development - Simulations Plus releases DDDPlus 1.0; new core product is first in industry
Drug Development - Spray-dried emulsions with drug dissolved in lipid characterized
Drug Development - Study outlines medical advances made due to biotechnology
Drug Development - Successful treatment reported with AT-1001 in rats with type I diabetes
Drug Development - Thallium flux assay identifies potassium channel modulators
Drug Development - The courage to change the rules: a proposal for an essential health R&D treaty
Drug Development - Thymalfasin may treat patients with chronic hepatitis B
Drug Development - Two major 8-prenylnaringenin metabolites are estrogenic in vitro
Drug Importation - Bill would let Texans buy prescriptions from Canada
Drug Importation - Minnesota governor, Pfizer executive defend drug importation
Drug Marketing - One-third of drug ads do not contain references supporting medical claims
Drug Marketing - Study reveals the huge influence of direct-to-consumer drug advertisements
Drug Metabolism - Novel CYP2A6 allele alters nicotine metabolism in black carriers
Drug Resistance - C. albicans transcription factor Upc2p regulated drug resistance
Drug Resistance - Biliary cirrhosis studied, bezafibrate induction of multidrug resistance shown
Drug Safety - Drug safety, bioterror top new U.S. FDA chief's priority list
Drug Safety - FDA aims to improve drug safety monitoring
Drug Safety - Healthcare groups form Maryland Safety through e-prescribing STEP initiative
Drug Safety - New board will check on risks of drugs after government approval
Drug Safety - Pharmaceutical company surprised by Canada's suspension of treatment for ADHD
Ecology - Lack of permanent pools from intermittent streams reduced algal productivity
Embryogenesis - Mitochondrial SDHD gene required for early embryogenesis
Embryonic Stem Cell Research - ESC aggregation induces Nanog repression and primitive endoderm differentiation
Emerging Viral Infections - Emergent viral infections often due to crossing species barrier
Encephalitis - Gene dysregulation found in cortex of HIV encephalitis patients
End-Stage Kidney Disease - Renal transplants benefit familial Mediterranean fever amyloidosis patients
Endothelium - Uterine endothelium studied, relaxant effect of vasoactive polypeptide shown
Enterococcus Vaccine - Rationale for developing immunotherapy against enterococci presented
Environmental Health - Newly developed drinking-water biofilms favor growth of Nitrosomonas-type AOB
Enzymology - KRN633 eliminates angiogenic growth in solid tumors
Enzymology - Proteases mark the survival of node-negative breast cancer
Enzymology - Recent findings illuminate research in enzymology
Enzymology - Reports add new data to enzymology research
Epilepsy Therapy - Carbenoxolone has significant anticonvulsant effects in rats
Erectile Dysfunction - Erectile dysfunction common in Japanese men with type 2 diabetes
Esophageal Cancer - Esophageal adenocarcinoma cells treated with hemocyanin examined
Estrogen - Brain lipid peroxidation studied, protective effect of estrogen revealed
Ethics - How should health professionals communicate risk to patients?
Facilities - Lybradyn graduates from Chicago Technology Park, PharmaIn takes over lab space
Fatty Liver Disease - Weight loss surgeries can improve or correct liver diseases
Finance - Biopharma reports strong growth in consolidated operating income
Finance - Biopharmaceutical company reports 4Q, year-end 2004 financial results
Finance - Biopharmaceutical firm closes common stock offering
Finance - Biopharmaceutical firm files registration statement for IPO
Finance - Biopharmaceutical firm reports loss of $0.16 per share
Finance - Biotech company receives $8.3M in funding from private investors
Finance - Biotech firm reports income of $0.34 per share
Finance - Biotech reports 2004 revenues of $410.4 million
Finance - Biotechnology announces transition quarter financial results
Finance - Biotechnology company reports fiscal 2005 second quarter results
Finance - Biotechnology company reports fourth quarter, year-end financial results
Finance - Development and discovery company reports improved financial results
Finance - Drug development company files registration statement for public equity offering
Finance - Drug distributor declares 17th consecutive quarterly cash dividend
Finance - Drug- and diagnostic-discovery company reports $13.7M net loss for 2004
Finance - Healthcare Dialog parent company announces move to OTC Bulletin board
Finance - Healthcare products maker reports net income rise of 42%
Finance - IT company records profitable fiscal year with significant revenue, growth
Finance - Imaging company fails to meet full-year financial guidance
Finance - Information solutions provider reports 16% increase in fourth quarter revenues
Finance - Insulin-focused drug development company to exercise option to purchase shares
Finance - Medical waste management company reports fourth quarter, full year 2004 results
Finance - Nutrition bioscience company reports improved second quarter results
Finance - Oncology company reports loss of $0.01 per share
Finance - Oncology-focused biopharmaceutical company reports 4Q, fiscal 2004 results
Finance - Ophthalmology company's fourth quarter earnings rise 39.9%
Finance - Patient safety solutions provider announces fourth quarter and 2004 results
Finance - Personal care products company reports fourth quarter and year-end revenue
Finance - Pharmaceutical company announces 2004 financial results
Finance - Pharmaceutical company reports fourth quarter and full year 2004 results
Finance - Pharmaceutical company reports fourth quarter and year-end results
Finance - Pharmaceutical distributor reports 12% increase in sales
Finance - Pharmaceutical firm completes 1-for-5 reverse stock split
Finance - Pharmaceutical firm exercises over-allotment option by underwriters
Finance - Pharmaceutical firm prices follow-on stock offering
Finance - Pharmaceutical firm receives contract for 1.5M Ribavirin injections
Finance - Pharmaceutical firm reports 15.5% sales increase in fourth quarter
Finance - Pharmaceutical firm reports 213% increase in 2004 revenue
Finance - Pharmaceutical firm reports loss of $0.07 per share
Finance - Pharmaceutical firm reports placement of $170M
Finance - Pharmacogenomic-focused pharma reports increased revenues and losses in 2004
Finance - Small molecule therapeutics pharmaceutical company announces IPO
Finance - Technology company announces record financial results
Finance - Vaccine maker closes $3.77 million private equity financing
Food Safety - Acceptable daily intake evaluated
Food-Borne Pathogen - C. jejuni survives on fresh produce long enough to pose consumer risk
Food-Borne Pathogen - Cold storage of grapefruit decreases survival of salmonellae
Fungal Infection - Phase 3 trial results evaluating anidulafungin for fungal infection announced
Gastric Infection - Review explores effect of H. pylori infection on micronutrient malnutrition
Gastroenterology - Angiogenin may influence the pathogenesis of inflammatory bowel disease
Gastroenterology - Studies advance knowledge in gastroenterology research
Gastroenterology - Vasoactive growth factors augment the healing of gastric ulcers
Gene Research - BLM gene interactions are detected in human cells
Gene Research - Gene profiles delineate the phenotypic character of human disease
Gene Research - Mammalian cortistatin is analogous to a non-mammalian somatostatin variant
Gene Research - Non-specific silencing complicates the use of small interfering RNA
Gene Research - Patients with polycythemia vera have rearrangements on chromsome 20
Generic Drugs - Company begins shipping Itraconazole capsules
Generic Drugs - Generic drug-focused company gets U.S. FDA approval of chewable antibiotic tabs
Generic Drugs - Pharma company cleared to market Megestrol Acetate Oral Suspension
Generic Drugs - Pharma company receives approval for Citalopram Hydrobromide tablets
Geriatrics - Humans display age and cataract-specific gene changes in the lens
Gestation - Dentate gyrus potentiation analyzed, role of infuled benzo(A)pyrene shown
Glioma Therapy - Selective estrogen receptor modulators induce glioma cell apoptosis
Glycemic Control - Glucose control in diabetes reviewed
Glycoprotein - P-glycoprotein studied, role in brain uptake of dextromethorphan revealed
Gynecology - Atrasentan augments therapies targeting ovarian carcinoma
Gynecology - Endothelin receptor blockade may eliminate COX-2-associated ovarian cancer
HIV/AIDS Diagnostics - Diagnosis not always self-evident in early stage of HIV-associated wasting
HIV/AIDS Diagnostics - HIV antibody/antigen assays perform better than antibody-only assays
HIV/AIDS Diagnostics - Research shows HIV screening is cost effective
HIV/AIDS Drug Development - Active site conformation used for HIV-1 integrase inhibitor design
HIV/AIDS Drug Development - Hops Humulus lupulus extract inhibits HIV replication
HIV/AIDS Drug Development - Thia-DCK analogs inhibit HIV-1
HIV/AIDS Drug Monitoring - Intracellular pharmacology of protease inhibitors improves therapeutic efficacy
HIV/AIDS Healthcare - Over-emphasis on food aid at expense of public health interventions in S Africa
HIV/AIDS Lipodystrophy - IGFBP-3 protease significant regulator of bioactive IGF-I in HIV-lipodystrophy
HIV/AIDS Opportunistic Infection - C-18 mutations critical for CCR5-binding/HIV-1 fusion inhibition
HIV/AIDS Pathogeneis - HIV-1 envelope facilitates contagious apoptosis
HIV/AIDS Pathogenesis - HIV-1 can dysregulate CD4+ T cells that express CXCR4
HIV/AIDS Pathogenesis - Plasma IL-18 associated with viral load/disease progression in HIV-1-infection
HIV/AIDS Pathogenesis - SOCS box in HIV-1 Vif that mediates its interaction with ElonginC characterized
HIV/AIDS Pathogenesis - T-cell activation leads to poor activation of HIV-1 clade E LTR
HIV/AIDS Pathogenesis - Thioester stability does not correlate significantly with anti-HIV-1 activity
HIV/AIDS Prevention - Chinese rural-to-urban migrants participate in AIDS prevention programs
HIV/AIDS Prevention - School-based intervention for HIV/AIDS prevention has positive impact
HIV/AIDS Research - APOBEC3B and APOBEC3C are potent inhibitors of SIV replication
HIV/AIDS Research - Cellular adhesion to VCAM-1 mediated by VLA-4 is suppressed after treatment
HIV/AIDS Research - Evans Blue inhibits NF-kappaB-DNA binding
HIV/AIDS Research - HIV LTR-dependent Bax expression selectively induces apoptosis in Tat+ cells
HIV/AIDS Research - SOCS-box phosphorylation regulates assembly of HIV-1 Vif-Cul5 complex
HIV/AIDS Screening - Coalition on HIV/AIDS applauds new study recommendation to test all adults
HIV/AIDS Therapy - Difference in median CD4 increase in HIV subtype B vs. non-B after PI therapy
HIV/AIDS Therapy - Drugs to inhibit drug-resistant HIV reverse transcriptases developed
HIV/AIDS Therapy - Entry inhibitor BMS-378806 may have reduced efficacy against non-B HIV-1
HIV/AIDS Therapy - HIV patients living longer with better drugs
HIV/AIDS Therapy - New research in the area of HIV/AIDS therapy detailed
HIV/AIDS Therapy - Studies describe new findings in HIV/AIDS therapy research
HIV/AIDS Treatment - Boston doctors report growing resistance to HIV drugs
HIV/AIDS Treatment - Time delay model shows possible effects of HAART on HIV dynamics
HIV/AIDS Vaccine - Advances in diagnosis and treatment of acute HIV-1 infection reviewed
HIV/AIDS Vaccine - Collaborators expand phase 1 clinical trial of HIV/AIDS vaccine program to India
HIV/AIDS Vaccine - Conformational changes during T cell receptor engagement reported
HIV/AIDS Vaccine - HIV induces and maintains suppression of thymocyte proliferation
HIV/AIDS Vaccine - Rise in immune activation linked to alterations in immune function
HIV/AIDS Vaccine - T cell receptor recognition motifs govern immune escape in SIV
HIV/AIDS Vaccines - Recent findings in HIV/AIDS vaccines described
HIV/AIDS Wasting - HIV-associated wasting exacerbated by reduced food intake/GI dysfunction
HIV/AIDS-Related Aspergillosis - Chest film plus clinical data improves IPA diagnosis in HIV patients
HIV/AIDS-Related Cryptococcosis - HIV infection is the most important risk factor for cryptococcosis
HIV/AIDS-Related Encephalitis - CD163 identifies a unique population of ramified microglia in HIV encephalitis
HIV/AIDS-Related Infection - Strong correlation between eosinophilia and helminthiasis in HIV infection
HTLV-1 Infection - Mathematical model studies the dynamics of HIV-1 infection of CD4+ cells
Haemophilus Vaccine - Antibodies against Haemophilus parasuis characterized
Hand Washing - Hand washing compliance in food service dependent on knowledge of supervisor
Head and Neck Cancer - Liposomal lurtotecan has limited efficacy in advanced SCCHN
Head and Neck Cancer - U.S. FDA grants orphan drug designation for Proxinium
Healthcare Coverage - Doctor helping other doctors reduces drug costs for poor
Healthcare Coverage - Equitable allocation of antiretrovirals sought
Healthcare Coverage - Pennsylvania budget preserves protection for vulnerable citizens
Heart Failure - Excretory contribution of ETB receptor was attenuated in congestive HF
Heart Failure - Heart failure society kicks off awareness campaign
Heart Failure - Thyroid hormone receptor-binding compound may be adjunct to standard HF therapy
Heart Failure - U.S. FDA accepts NDA resubmission for BiDil
Hematology - Hepatitis C therapy alters hematological parameters in HIV-coinfected patients
Hematology - Researchers detail new studies and findings in the area of hematology
Hematology - Researchers provide details of new studies and findings in the area of hematology
Hematology - Tunisian patients harbor a common mutation on the hemochromatosis gene
Hematopoiesis - Panorama of lineage-specific transcription occurs during hematopoiesis
Hemovigilance - Norway has strict rules regarding hemovigilance for transfusion
Heparin - Practical use of generic low-molecular-weight heparins reviewed
Hepatitis B Vaccine - European approval announced for Fendrix, GSK's hepatitis B vaccine
Hepatitis C - Liver-targeted drug delivery article published in journal
Hepatitis C Therapy - Enrollment, randomization, dosing completed in Albuferon phase II trial
Hereditary Angioedema - Companies sign manufacturing agreement for recombinant human C1 inhibitor
Histamine - Histamine receptor studied, nature of phosphorylations clarified in intact cells
Hormone Replacement Therapy - Changing chemistry helps explain estrogen threat to the heart
Hormone Replacement Therapy - Research sheds light on why estrogens produce unintended results in women
Huntington Disease - Intrabodies confront dysfunctional protein activity
Hyperglycemia - Postprandial hyperglycemia in type 2 diabetes reviewed
Hyperparathyroidism - Hyperparathyroidism studied, oxacalcitriol dose-response revealed
Hypertension - COX-2 inhibitors associated with blood pressure elevation
Hypertension - Microdosing studies completed for hypertension treatment
Hypoglycemia - Consequences of nocturnal hypoglycemia in type 1 diabetes reviewed
Hypoglycemia - Identification and impact of asymptomatic hypoglycemia reviewed
Hypothyroidism - Pharma company introduces a new thyroid replacement therapy
Imidazole - Formamidopyrimidine-DNA glycosylase studied, active site behavior clarified
Immunology - CD4 mimicry by anti-idiotypic antibody based on conformational epitope
Immunology - Dr. Thomas F. Gajewski joins clinical advisory board
Immunology - Heterogeneity of Ag-specific CD4 cell responses regulated by Ag exposure/Ag load
Immunology - Innate immune responses during infection reviewed
Immunology - Researchers' work adds to immunology body of knowledge
Immunotherapy - Interleukins and gene corrected bone marrow cells remedy immunodeficiency
Immunotherapy - TNF-alpha targeted as a key disease molecule
Infection Control - Nebulized saline treatment reduces bioaerosol particle exhalation
Infectious Bronchitis Vaccine - H strain of avian infectious bronchitis virus as vaccine reviewed
Infectious Pancreatic Necrosis Virus - Infectious pancreatic necrosis virus strains characterized
Inflammation - Beta-adrenergic receptor studied, neutrophil regulation clarified
Inflammatory Bowel Disease - Antioxidant PDE4 inhibitor tetomilast shows promise for treatment
Inflammatory Disease - Alpha1-antitrypsin gene deficiency in mice resembles human fetal disease
Inflammatory Disease - Transglutaminase 2 induces NF-kappa B activation via BV-2 microglia pathway
Influenza - Educational action needed to curb flu outbreaks in the workplace, survey shows
Influenza Vaccine - Flu shots don't save lives in elderly, study suggests
Influenza Vaccine - Prevention of lower respiratory tract infections with vaccines reviewed
Influenza Vaccine - siRNAs show promise for treatment of influenza
Influenza Vaccines - New findings in influenza vaccines described
Influenza Virus - Genomic segments of influenza B virus strains mapped
Information Technology - Center for Evidence Based Pharmacy Practice pharmacy cost control toolkit
Information Technology - Drug company announces individual bar coding on all insulin vials
Information Technology - GNSI partners to create single point of entry for e-submissions to the FDA
Information Technology - Hospital prepares to implement wireless barcode medication charting
Information Technology - Library group urges researchers to comply with U.S. NIH public access policy
Information Technology - New method released to improve the management of opinion leader relationships
Information Technology - Pennsylvania hospital group upgrades to enterprise clinical software system
Information Technology - Telemedicine company forms alliance to promote blood monitoring system
Information Technology - U of Chicago Comer Children's Hospital selects inventory management system
Information Technology - University of Rochester Medical Center extends IT solution system-wide
Insulin - Insulin isotherms in ethanol-water reversed phase systems presented
Insulin Delivery - Recent advances in inhaled insulin therapy to treat diabetes reviewed
Insulin Resistance - Pro12Ala polymorphism of PPAR-gamma gene linked to insulin resistance
Insulin Therapy - Company reports preliminary results of a phase IIb clinical study of Oral-lyn
Kaposi Sarcoma-Associated Herpesvirus - E2-binding C4HC3-type RING domain identified in KSHV K3N-terminal domain
Kaposi Sarcoma-Associated Herpesvirus - New research in the area of kaposi sarcoma-associated herpesvirus detailed
Legal Issues - Jury finds 15-year-old boy guilty in Zoloft defense trial; 30 year sentence
Legal Issues - St. Francis Hospital settles vaccine fraud case
Legal Issues - Wrongful death lawsuit filed against makers of children's ibuprofen product
Leishmaniasis Therapy - Effects of renal impairment on antimony pharmacokinetics determined
Leukemia - A cargo peptide transporter system halts aggressive leukemia and lymphoma
Leukemia - Agreement with U.S. FDA on protocol assessment of leukemia treatment announced
Leukemia - Vaccine may complement conventional treatment for chronic leukemia
Lipotoxicity - Lipotoxicity is an imbalance between lipogenesis de novo & fatty acid oxidation
Liver Cancer - Nobiletin inhibits hepatocarcinoma cell proliferation in vitro
Liver Cancer - Researchers provide details of new studies and findings in the area of liver cancer
Malaria - Histidine-rich protein-based malaria drug assay developed, field use reported
Malaria - Incidence data over 30 years reveals trends in Malaria transmission
Malaria - New data illuminates research in malaria
Malaria - Simple treatment could prevent many child malaria deaths
Malaria Vaccine - Alanine-rich repeats are intact in Plasmodium falciparum MSP3
Malaria Vaccine - Allelic dimorphism found in surface protein of Plasmodium vivax
Malaria Vaccine - Sequence diversity of P. falciparum merozoite protein reported
Malaria Vaccines - Researchers describe findings in malaria vaccines studies
Malaria Vaccines - Studies advance knowledge in malaria vaccines research
Malignant Melanoma - Viragen files to expand cancer approval for Multiferon in Sweden
Marketing - Companies are embracing pharma sales technology
Melanoma - Microtubule-dependent MMP-2/MMP-9 exocytosis needed for cell invasion
Melanoma Vaccines - Data advance knowledge in melanoma vaccines research
Melioidosis Vaccine - Subunit vaccines against experimental melioidosis evaluated
Membrane Topology - Acid-sensing ion channel 2a analyzed, membrane topology clarified
Memory - Water maze learning in hyperglycemic-hyperinsulinemic rats studied
Meningococcus Vaccine - Public health management in invasive meningococcal diseases reviewed
Mental Health - Detailed measurements clarify the genomic etiology of bipolar disorder
Mental Health - Hyperactive cannabinoid systems may be involved in schizophrenia etiology
Mergers & Acquisitions - Antisoma completes acquisition of Aptamera
Mergers & Acquisitions - Aptamera's shareholders approve acquisition by Antisoma
Mergers & Acquisitions - Canadian business Multichem acquired for CDN $23.8M
Mergers & Acquisitions - Cancer treatment systems company to be acquired by Cytyc Corporation
Mergers & Acquisitions - Cytyc expands women's health presence with acquisition
Mergers & Acquisitions - Integrated drug development company acquires Scantox
Mergers & Acquisitions - Japanese pharmaceutical company to merge Syrrx into Takeda Group
Mergers & Acquisitions - Pharmaceutical and chemical company acquires business unit of Avecia
Mergers & Acquisitions - Pharmaceutical services company completes sale of drug delivery business
Mesothelioma - Petition urges Congress to fund mesothelioma research
Metabolic Syndrome - Metabolic syndrome drug pipeline report announced
Metabolic Syndrome - Researchers' data advance metabolic syndrome research
Metabolic Syndrome - Researchers' work adds to metabolic syndrome body of knowledge
Metapneumovirus Vaccine - In ovo vaccination with avian metapneumovirus vaccine reported
Methicillin-Resistant Staphylococcus Aureus - Gentamicin-susceptible MRSA clone in Rio de Janeiro resembles NY/Japanese clone
Methicillin-Resistant Staphylococcus Aureus - Oils effect antibacterial against epidemic methicillin-resistant S. aureus
Microbicidal Vaginal Gel - Spread of microbicidal vaginal gel dependent on time and volume
Mosquito-Borne Disease - Mosquito densoviruses used to control Aedes aegypti mosquitoes
Multiple Sclerosis - Clinical study of mitoxantrone is in progress to assess long-term safety
Multiple Sclerosis - Current approved options for treating patients with multiple sclerosis
Murine Mesothelioma - Pharma company begins preclinical study of murine mesothelioma treatment
Mutagenesis - Aipl1-deficient mice model a disorder that causes pediatric blindness
Mycoplasma - PCR method for mycoplasma testing of cell cultures developed
Mycoplasma Infection - Bovine pinkeye outbreak associated with mixed mycoplasma infection
Natural Products - ESPS elevated soybean production
Nephrology - Scientists identify potential therapy for kidney failure
Nephrology - Sp1 activation is crucial for claudin-19 gene expression in kidney cells
Neural Stem Cell Research - Cell-cell & cell-extracellular matrix contacts essential for NSC maintenance
Neural Stem Cell Research - ESC-derived neurons response in a manner similar to primary central neurons
Neural Stem Cell Research - Endoneurial fibroblasts are derived from neural crest
Neural Stem Cell Research - Hes genes regulate nervous system by controlling timing of NSC differentiation
Neural Stem Cell Research - Oct-3/4 repression accelerates differentiation of neural progenitor cells
Neural Stem Cell Research - Oligodendrocyte conversion to NSLC depends on progressive chromatin remodeling
Neural Stem Cell Research - Pergolide protects against levodopa-induced cytotoxicity of neural stem cells
Neural Stem Cell Research - Programmed cell death of adult-generated hippocampal neurons mediated by Bax
Neural Stem Cell Research - Vax1 potent regulator of subventricular zone organization and NSC proliferation
Neurodegeneration - Genetic fingerprints exemplify type 2 Gaucher disease
Neurodegeneration - Reports describe recent advances in neurodegeneration research
Neurology - Nurr1 expression studied in the brain, effect of chronic lithium revealed
Neuroscience - Brain synapse formation linked to proteins
Neuroscience - Mitoxantrone should be restricted to certain multiple sclerosis patients
Neuroscience - Study explored changes resulting from long-term endothelin antagonism
Neuroscience - VEGF levels rise when peritumoral edema accompanies intracranial meningiomas
Norovirus - Genogroup I/II noroviruses detected in stool samples by real-time RT-PCR
Nosocomial Infections - Genomic factors dominate Pseudomonas aeruginosa in cystic fibrosis patients
Nuclear Membrane - Nuclear pore-directed transport of proteins studied, conditions clarified
Obesity - Biotech company focused on metabolic disorders obtains license to obesity genes
Obesity - Genetics factors partly responsible for middle-age spread in middle-class males
Obesity Pathogenesis - Researchers publish new studies and findings in the area of obesity pathogenesis
Obesity and Diabetes - Findings advance knowledge in obesity and diabetes research
Obesity and Diabetes - Obesity, bariatric surgery, and type 2 diabetes reviewed
Obesity and Diabetes - Protein kinase C interactions in adipocytes regulate glucose uptake
Obesity and Diabetes - Signal pathway regulating plasminogen activator inhibitor identified
Obstetrics - High maternal hepatitis C virus levels cause transmission to fetuses
Oncology - Angiogenic protein levels differentiate malignant and nonmalignant ascites
Oncology - Antisense molecules targeting alpha folate receptor hinder breast cancer cells
Oncology - Data advance knowledge in oncology research
Oncology - Low platelet counts denote multicentricity in HCV-related liver cancer
Oncology - New data illuminates research in oncology
Oncology - Pro-apoptotic gene therapy destroys prostate cancer
Oncology - Recent findings illuminate research in oncology
Oncology - Researchers publish new studies and findings in the area of oncology
Oncology - Studies add new findings to oncology body of knowledge
Oncology - Systems biology-tech firm gets U.S. NCI grant for analysis of cancer networks
Ophthalmology - Endothelin-1 eyedrops produce retinal vasculopathy models
Osteoporosis - Calcitonin effectively decreases bone resorption in at-risk elderly women
Osteoporosis - Calcitriol improves streptozotocin-induced diabetes, recovers BMD in rats
Osteoporosis - Data presented on 5 years of treatment with risedronate
Osteoporosis - Pharma company adds time to prepare new drug application for osteoporosis drug
Ovarian Cancer - Murine models of early and late stage disease help evaluate therapeutics
Ovarian Cancer - Phase III clinical trial on monoclonal antibody is enrolling patients
Ovarian Cancer - Researchers evaluating new therapy for advanced ovarian cancer
Ovarian Cancer - U.S. FDA grants approval to ovarian cancer treatment following data submission
Pain Management - Healthcare company introduces topical system to reduce needlestick pain
Pain Management - New study links Vioxx, Celebrex, Bextra to increased cardiovascular risk
Pain Management - Painkiller sales decline shows more pain patients may be suffering
Pain Medicine - COX-2 product offers good and bad news in "test tube" strokes
Pain Medicine - Still more to learn before treating rotator cuff injuries
Pain Medicine - Two products of diclofenac sodium suppositories compared
Pain Medicine - Vioxx nearly doubled cardiovascular risks in cancer prevention study
Pancreatic Cancer - BIA shown as prognostic indicator in pancreatic cancer
Pancreatic Cancer - Novel putative protein biomarkers and therapeutic targets identified
Pancreatic Cancer - Pancreatic cancer therapy clinical trial results announced
Pancreatic Cancer - Recent findings in pancreatic cancer provide new insights
Pancreatic Cancer - Safety board gives go-ahead for ongoing trial of pancreatic cancer treatment
Pancreatic Islets - Adenoviral overexpression protects pancreatic islets from oxidation
Parasitology - Environment and parasite genetics dictate murine resistance to malaria microbes
Parkinson Disease - Pharmaceutical company moves Parkinson medication into phase III development
Patents - European patent office issues allowance for paclitaxel drug in Europe until 2017
Patient Education - Pictograms do not improve children's grasp of medicine information
Pediatric Apheresis - Technical risks considered in pediatric apheresis due to size of patient/donor
Pediatric Healthcare - Expensive drugs for rare illnesses increase pinch for state aid
Pediatric Healthcare - Schools responding to increasing use of hyperactivity drug
Pediatric Healthcare - Study supports benefits of giving dehydrated children fluids by mouth
Personnel - Australian oncology firm announces change in board of directors
Personnel - Biological company announces new chairman of the board
Personnel - Biopharma company elects president and chief operating officer
Personnel - Biopharmaceutical company adds two virologists to its scientific resource board
Personnel - Bioprocessing companies announce leadership team
Personnel - Biotech executive joins new biopharmaceutical company
Personnel - Biotechnology pharmaceutical company announces two senior management changes
Personnel - Bush fills long-standing vacancy at FDA with Univ. of Georgia graduate
Personnel - Dale A. Sander joins protein-therapeutics company as CFO and senior VP
Personnel - David A. Rutledge named CFO at nonprofit research organization
Personnel - Diagnostics company names Michael Silver VP of clinical research
Personnel - Dr. Joseph Rubinfeld resigns from board of Nipent maker
Personnel - Dr. Rafik H. Bishara joins cold-chain management company
Personnel - Drug discovery chemistry company promotes Mark Allen to senior vice president
Personnel - Drugmaker names Michael J. Gast, MD, PhD, as chief medical officer
Personnel - Gary Ingenito named senior VP of pharmacotherapeutics company
Personnel - Genomics company announces new board member
Personnel - Gustavsson to chair biopharmaceutical firm's advisory board
Personnel - Health care company mourns death of former executive
Personnel - Health technology company appoints executive vice president, general manager
Personnel - Herbert H. Mertens named VP, sales and marketing, of Powerlink maker
Personnel - IVAX announces new board of directors member
Personnel - Lifesciences organization announces new appointment to advisory board
Personnel - Medical device company names chief financial officer
Personnel - Metabolic profiling services hires new vice president of sales and marketing
Personnel - Michael W. Aguiar named chief financial officer by biopharmaceutical company
Personnel - Pharma company names chief business officer
Personnel - Pharma company president elected to California Healthcare Institute Board
Personnel - Pharmaceutical company announces new board member
Personnel - Pharmaceutical company appoints chief medical officer
Personnel - Pharmaceutical company appoints member of board of directors
Personnel - Pharmaceutical company names key outside director
Personnel - Pharmaceutical firm appoints Williams as VP, head of corporate development
Personnel - Pharmaceutical firm strengthens management team with new VP
Personnel - Protein-focused biopharmaceutical company appoints Theresa Heggie as GM, Europe
Personnel - Protein-focused biotech company names Dartmouth cancer researcher to board
Personnel - Regenerative medicine company announces executive appointments
Personnel - Robert E. Knowling, Jr. appointed chair of immune-based therapy company board
Personnel - Therapeutics company announces appointment of new board member
Personnel - Yong-Jian Geng, MD, PhD, joins advisory board of drug development company
Personnel - qNPA technology company names two researchers to scientific advisory board
Pertussis Vaccine - Antigenic variation linked to B. pertussis electrophoresis profiles
Pestivirus Vaccine - Phylogenetic analysis of bovine pestiviruses performed
Pharmaceutical Research - Bioanalytical company U.S. FDA continue talks regarding bioequivalence studies
Pharmaceutical Research - Studies show risk for serious side effects in drug combinations
Philanthropy - ExxonMobil announces more than $5 million in grants for malaria
Prodrug - Acyclovir studied, bioavailability and transport in Caco-2 cells revealed
Product Licensing - Fujisawa obtains the worldwide rights to antipsychotic agent
Product Licensing - Marketing agreement forged for treatment of dyslipidemia
Product Licensing - Ophthalmic company obtains rights to develop new treatment for dry eye
Promyelocytic Leukemia - Dominant molecular signatures of PML influenced by independent events
Prostate Cancer - IBt announces renewal of European distribution agreement
Protein Folding - Lysozyme refolding analyzed, influence of macromolecular crowding clarified
Protein Regulation - Mechanical stretch upholds the angiogenic potential of CCN1
Protein Signal - Signal transduction modulation through PrPc linked to lipid raft incorporation
Proteomics - Core protein processing varies with hepatitis C virus genotype
Proteomics - Findings advance knowledge in proteomics research
Proteomics - Human PTIP maintains genome stability
Proteomics - Ligand binding assay incorporated into centrifugal microfluidics platform
Proteomics - Researchers' work adds to proteomics body of knowledge
Proteomics - Study examined effects of ET-1 and aldosterone on COX-2 gene expression
Pseudomonas Vaccine - Vaccine against Pseudomonas aeruginosa infection developed
Psoriasis - Biopharmaceutical company achieves target enrollment for psoriasis trial
Psychopharmacology - Ketoconazole synergizes with allopregnanolone treatments in rat study
Pulmonary Arterial Hypertension - Encysive Pharma shares surge as Thelin drug meets late-stage study
Pulmonary Medicine - MMP1 gene polymorphism associates with chronic obstructive pulmonary disease
Pulmonary Medicine - Survivin and p53 modulate the influence of quercetin on lung cancer cells
Pulmonary Medicine - The role genetics plays in panbronchiolitis susceptibility is questionable
RNA Research - Potelligent RNAi launched for RNA research
RNA Research - Progress reported on infectious disease program using Neugene antisense drugs
Receptor Studies - ET-1 antinociceptive effect involved descending pain inhibitory system
Receptor Studies - Novel system improves cannabinoid receptor 2 purification
Receptor Studies - VPAC1 , VPAC2 , and PAC1 receptors in human tissues identified
Renal Anemia - Epoetin therapy during hemodialysis alters erythrocyte metabolism
Respiratory Medicine - Ultrasonic nebulization supports polyplex stability during aerosolization
Restless Legs Syndrome - Phase 2b clinical trial of drug for treatment of restless legs syndrome begins
Retinoblastoma - Study demonstrates effectiveness of drug in treatment of retinoblastoma
Rheumatology - Impaired vessel growth causes the vascular symptoms of systemic sclerosis
Rotavirus Vaccine - Rotavirus vaccines to prevent diarrhea in children reviewed
Salmonella Bacteremia - Risk factors identified for developing nontyphoid Salmonella bacteremia
Salmonella Enterica - Virulence gene expression profiles differ with type of S. enterica strain
Salmonella Vaccine - Method to estimate endotoxin in Salmonella vaccine developed
Salmonellosis - Prolonged incubation period of salmonellosis associated with low bacterial doses
Scedosporiosis - Liposomal amphotericin B effective in murine model
Schistosomiasis - Synergy increases granulomas induced by Schistosoma protein
Schistosomiasis Vaccine - Artemether triggers resistance against Schistosoma re-infection
Schizophrenia - Clinical data released for secretin in refractory schizophrenia
Severe Acute Respiratory Syndrome - Pharmaceutical company receives SARS vaccine funding
Sexual & Reproductive Health - Biopharmaceutical company reports results of female sexual dysfunction study
Sexual & Reproductive Health - Clinical trial: Testosterone spray enhances female sexual desire
Sexual & Reproductive Health - Immediate access to antibiotics stems spread of sexually transmitted diseases
Shellfish Poisoning - Low risk of azaspiracid poisoning from shellfish harvested at Portuguese coast
Staphylococcus Vaccine - Glucosamine polysaccharide shows promise for staphylococcal vaccine
Staphylococcus Vaccine - Humanized antibody targeting Staphylococcus aureus developed
Statins - More evidence presented on APOE genotype and baseline CRP relationship
Stem Cell Research - CD34+ cells generate phenotypically new monocyte in culture
Stem Cell Research - Early human T/NK/B progenitors cells in cord blood molecularly characterized
Stem Cell Research - G-CSF is best cytokine for PBSC mobilization despite efficacy/safety debate
Stem Cell Research - IL-16 plus thrombopoietin induces generation of tolerogenic dendritic cells
Stem Cell Research - IREM-1 is an inhibitory receptor expressed by myeloid cells
Stem Cell Research - Identifying adult SCs essential for understanding its dynamics during adult life
Stem Cell Research - MSCs acquire tissue specific morphology under minimal injury conditions
Stem Cell Research - PU.1 necessary for maintenance of fetal liver hematopoietic stem cells
Stem Cell Research - Phosphophoryn regulates MSC gene expression via integrin/MAPK signaling pathway
Stem Cell Research - Stop-EGFP mouse used to investigate clonal cell lineages
Stem Cell Transplantation - HLA mismatched SCT based on feto-maternal tolerance alternative to matched donor
Stem Cell Transplantation - Surrogate markers and agents for PBSC mobilization improve collection efficiency
Stem Cells Research - Epidermal stem cells regenerate a long-lasting epidermis
Stem Cells Research - Stem cells may be target cells in development of cancer
Streptococcus Vaccine - Host-pathogen interactions of Streptococcus pyogenes reviewed
Stroke - Confirmatory study of desmoteplase begins
Stroke - Stroke diagnosis, pharma, devices, and surgical intervention market researched
Systemic Lupus Erythematosus - Peptide ameliorates lupus manifestations
Thioredoxin - Dictyostelium discoideum thioredocin targets shown, properties revealed
Thioredoxin Reductase - Thioredoxin reductase studied, role in growth of lens epithelial cells revealed
Thrombosis - Clot-busting drugs may help detect potentially deadly leg clots
Thrombosis Therapy - Perceptions of generic warfarin by anticoagulation providers examined
Tissue Engineering - Acellular matrix possible for functional reconstruction the urogenital tract
Tissue Engineering - Biodegradable scaffolds used for reconstruction of urethral/ureteral tissue
Tissue Engineering - Biological vascularized matrix solves problem of perfusion in tissue engineering
Tissue Engineering - Nano-fibrous scaffolds developed for tissue engineering
Tissue Engineering - Optimized condition determined for creation of urothelium for large surfaces
Tissue Engineering - Ultrasound intensity effects collagen fiber formation for bone mineralization
Tobacco Use - Transcriptional effects of nicotine determined in five brain regions
Toxicology - Chitosan derivatives staunch genotoxicity
Toxicology - Dioxin has weak estrogenic activity in the uterus
Toxicology - Exposure to hydrocortisone impair fertility in prenatal female rats
Transdermal Drug Delivery - Limonene enhances skin permeability of nimodipine in vitro
Transdermal Drug Delivery - Magnolia lily oil improves skin permeation of theophylline and cianidanol
Transplant Medicine - Adefovir resolves drug-resistant hepatitis B after liver transplantation
Transplant Medicine - Adult living donor liver grafts meet the demand for donated organs
Transplant Medicine - Gene profiles show fractalkine plays a role in kidney allograft rejection
Transplant Medicine - Preoperative prophylaxis aids patients given HBV-related liver transplants
Tuberculosis Vaccine - DNA vaccine protects mice against primary TB infection
Tuberculosis Vaccines - Researchers' findings advance tuberculosis vaccines research
Type 1 Diabetes Research - Company announces public release of phase IIa data on Basulin
Urinary Incontinence - Transdermal oxybutynin patch developed
Urinary Tract Infection - Progress toward a new remedy for UTI?
Vaccine Development - Host cell-pathogen interfaces reviewed
Vaccine Development - MHC affects genetic resistance to infectious bronchitis vaccines
Vaccine Efficacy - scFv reactivity enhanced after mixing with anti-tag monoclonal antibody
Vaccine Safety - Fatalities following allergen immunotherapy reported
Vaccines Adjuvant - New findings in vaccines adjuvant described
Vaccines Development - New findings in the area of vaccines development described
Vaccinia Virus - Exit of vaccinia virus from infected cells reviewed
Varicella-Zoster Vaccine - Genetic profile of Oka varicella vaccine virus variant presented
Vector Development - Low-pressure chromatography synthesizes PEG-peptides for gene delivery
Venous Thrombosis - Pharmaceutical company initiates clinical trial for oral anticoagulant
Vibrio Cholerae - Vibrio cholerae O1 is a resident of Argentinean waters
Viremia - Most episodes of transient HIV "blips" not clinically significant
Virology - Bone marrow transplantation raises the risk for viral reactivation
Virology - Data advance knowledge in virology research
Virology - Hepatitis B virus genotype D backs aggressive liver disease
Virology - Oncolytic adenovirus selects hypoxic tumor cells for destruction
Virology - Recent findings illuminate research in virology
Virology - Recombinant adenoviruses initiate complement activation
Virology - Recombinant baculovirus vectors could transport genes to the nervous system
Virology - Reports add new data to virology research
Virology - Reports advance knowledge in virology research
Virology - Retroviruses transduce embryonic stem cell-derived hematopoietic progenitors
Yellow Fever Vaccine - International standard for yellow fever vaccine established
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