NewsRx

Search our medical news database

Drug Week

Susan Hasty, Publisher

Table of Contents . . . March 11th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Alzheimer Disease - Phenserine fails to achieve significant efficacy in phase III trial

Bioterrorism - Biotechnology company working on vaccine development against bioterror agents

Drug Development - Anamantle HC cream launched as hemorrhoid therapy

Drug Development - Pharmacogenomics predicted to have major impact in future drug development

Hormone Replacement Therapy - HRT controversy raises drug safety issues

Acetylcholine Receptors - Alpha-conotoxins studied, distinct nicotinic acetylcholine receptor sites shown

Acinetobacter -  Acinetobacter isolates show decrease antibiotic susceptibility over 10+ year

Addiction Medicine - Research identifies proteins crucial to brain's information superhighway

Age-Related Macular Degeneration - Company announces reimbursement terms for Macugen

Agricultural Pest -  B. latifrons identified by rapid real-time PCR using SYBR Green chemistry

Allergy Medicine - DC activation by LPS down-regulates birch allergen-induced Th2 differentiation

Allergy Medicine - Immunotherapy in age of anti-IgE reviewed

Allergy Medicine - New information in pediatric allergology reviewed

Allergy and Immunology - Anhydrase II antibody is not a prognostic marker of autoimmune pancreatitis

Allergy and Immunology - Circulating dendritic cells fall short in hepatitis B virus-infected humans

Allergy and Immunology - Interleukin-10 gene therapy protects islet grafts after transplantation

Alzheimer Disease - Pharmac companies collaborate on treatments for neurodegenerative diseases

Alzheimer Disease - Rat brain proteins may mediate neuroprotective actions of grape seed extract

Amyloid Formation - Amyloid formation analyzed, thermodynamic parameters directly measured

Andropause - Company begins phase I clinical trial for its second SARM, ostarine

Anesthesia - Maximum recommended doses of local anesthetics aren't evidence based

Angiology - Celecoxib uses multiple signaling mechanisms to suppress neovascularization

Angiology - Findings in angiology provide new insights

Angioplasty - Automated system suitable for monitoring response to anti-platelet therapy

Anthrax Vaccine - Rabbit and primate models of toxin-targeting anthrax vaccines reviewed

Anti-Infectives - Grapefruit juice enhances antischistosomal effects of artemether

Antibacterial Agents - Positive results reported for Microbisol

Antibiotic Resistance - Penicillin resistance of Streptococcus pneumoniae in Spain decreasing

Antimicrobials - Production of an antifungal molecule by B. licheniformis BC98 optimized

Apoptosis - Histatin analyzed, inhibition of apoptosis in human gingival fibroblasts shown

Arthritis - U.S. FDA opens hearing on arthritis drug safety

Asthma - African-Americans may need more medication to control asthma

Asthma - Montelukast significantly reduces asthma exacerbations in young children

Asthma - Published study finds mother's asthma or allergies may increase risk of autism

Atherosclerosis - Carotid atherosclerosis incidence high in diabetes plus nephropathy

Atherosclerosis - Trial of RUS 3108 begin in Ireland

Attention Deficit Hyperactivity Disorder - Pharmaceutical company provides update on clinical trials and pipeline

Bacteriology - Antibacterial effect of wine may be a synergy of organic acids, ethanol, low pH

Bacteriology - Melittin analyzed, hemolytic role of leucine zipper motif revealed

Beta-Blockers - Increasing the use of beta-blockers has potential for important clinical impact

Biomedical Engineering - Nanobiohybrids implement fluorescent protein transfection

Biomedicine - Data mining in biomedicine realized by using digital and molecular libraries

Biotechnology - Novel immunoassays for biochanin A developed

Biotechnology - Novel method enables controlled generation of liquid crystal defects

Bone Repair - Heparan sulfate mimetic augments the healing of craniotomy defects

Bovine Thyroglobulin - Bovine thyroglobulin studied, nature of multimerization clarified

Breast Cancer - Earlier fulvestrant use in heavily pretreated older women may be more effective

Breast Cancer - Hypothyroidism associated with reduced breast cancer risk

Breast Cancer - Recent findings in breast cancer provide new insights

Brucella - Genetic bases of rifampin resistance in Brucella reported

Business & Finance - Antibiotics-focused biopharmaceutical company announces corporate restructuring

Business & Finance - Biopharma company reports second quarter results

Business & Finance - Biotechnology company announces year end results, progress

Business & Finance - Company releases financial results, provides summary of R&D efforts

Business & Finance - Cytoskeleton-focused company reports $2.2M Q4 revenues, provides oncology update

Business & Finance - Emtriva maker reports increased Q4 and full-year revenues

Business & Finance - Health care products company announces financial results, new hire

Business & Finance - Pharmaceutical company announces agreement to manufacture Raloxifene tablets

Business & Finance - Pharmaceutical company announces first quarter ended December 31, 2004, results

Business & Finance - Pharmaceutical company makes strategic investment in Triad Pharmaceuticals, Inc.

Business & Finance - Pharmaceutical firm reports loss of $0.14 per share, pipeline update

Business & Finance - Pharmaceutical firm reports on alliance, financial results

Business & Finance - TF decoy-technology company reports improved revenues, lower losses in 2004

Business & Finance - Thermal solutions company secures funding to develop thermoelectric devices

Business Update - Banta Corp. sells its healthcare products business

Business Update - Biomedical company's distribution network expands in China

Business Update - Biomedical foods company receives large purchase order

Business Update - Biopharma company and EnVivo sign HDAC collaboration agreement

Business Update - Biopharmaceutical company signs long-term supply agreement

Business Update - Carni Q-Gel Forte receives U.S. Pharmacopeia's verification approval

Business Update - Cobra extends its agreement to provide long-term manufacture of REOLYSIN

Business Update - Company applies for membership in the Cryogenic Society of America

Business Update - Dermatology firm acquires U.S., Canadian rights to Solage

Business Update - Dermatology firm announces stock sale

Business Update - ExonHit launches SpliceArray Service with GPCR and ion channel microarrays

Business Update - German biotech company transfers lab automation business to AVISO GmbH

Business Update - Glaxo makes $1.0 million payment, starts phase 2 studies of oral platelet drug

Business Update - Maker of OTC migraine remedy recaps achievements of past 12 months

Business Update - Model for Bio-Healthcare Park unveiled at ceremony for Pharmaplaz in Ireland

Business Update - Oncology company moves HQ and R&D operations to San Diego facility

Business Update - Pharma-focused IT company announces relocation of worldwide headquarters

Business Update - Pharmaceutical company expands animal health business with acquisition

Business Update - Pharmaceutical company release liquid iron supplement

Business Update - Profit rises 12% at pharmacy-benefits manager MeD.C.o Health

Business Update - Supply company created to develop and market clinically tested products

Business Update - Survey shows pharmaceutical firms must innovate smarter and faster

Business Update - Technology company signs supply agreement with Roche Molecular Systems

Business Update - Technology consulting and engineering firm joins MDL Isentris Alliance

Business Update - e-Pharmaceutical marketing company recognized as eDetailing vendor market leader

Calcium Channels - Calcium channels studied, role of voltage gating in aldosterone secretion found

Cancer Research - Cysteine cathepsins allowed the invasion of AdoMetDC-transformed rodent cells

Cancer Research - Gleevec-resistant gastrointestinal stromal tumors therapy shows positive results

Cancer Research - Trial to study oral spray to reduce chemotherapy-induced nausea

Cancer Therapy - 'T-body' approach may have therapeutic potential in disseminated prostate cancer

Cancer Therapy - BCL-2 inhibition sensitizes malignant cells to cancer immunotherapy

Cancer Therapy - Common virus becomes a new target for cancer treatment

Cancer Therapy - Company to discontinue further development of Pegamotecan

Cancer Therapy - Doxorubicin nano-aggregates stabilized by DOX-PEG-FOL conjugates

Cancer Therapy - EPO induces cancer cell resistance to ionizing radiation and cisplatin

Cancer Therapy - Genomics companies partner to investigate role of cancer genes

Cancer Therapy - New data illuminates research in cancer therapy

Cancer Therapy - Normalization windows sensitize cancer cells to therapy

Cancer Therapy - Particle therapy technology to treat tumors to be installed at Heidelberg center

Cancer Therapy - Pharmaceutical company receives PDUFA dates for chemo drug, reports finances

Cancer Therapy - Phase I human clinical trial with 1D09C3 begins

Cancer Therapy - Photodynamic therapy successfully treated feline skin cancer

Cancer Therapy - Recent findings illuminate research in cancer therapy

Cancer Therapy - Researchers describe how tumors acquire resistance to kinase inhibitors

Cancer Therapy - Resveratrol displayed chemopreventive effects

Cancer Therapy - Silibinin limits doxorubicin-induced toxicity in murine tumor models

Cancer Therapy - ZD6474 arrests the growth of gefitinib-sensitive tumors

Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge

Cancer Vaccines - Studies advance knowledge in cancer vaccines research

Canine Distemper Virus - Hemagglutinin gene of canine distemper viruses analyzed

Cardiology - CD28 peptidemimic prolongs survival of cardiac allografts

Cardiology - Cost of thorough QT/QTc study may be reduced to 25-30% of the cost of simple ECG

Cardiology - Defibrillator manufacturer introduces new AED for professional rescuers

Cardiology - Diagnosis of antiphospholipid syndrome is difficult in anticoagulated patients

Cardiology - Endothelin-1 enables cardiac cells to tolerate hypoxia

Cardiology - Recent findings in cardiology described

Cardiology - Simvastatin boosts the efficacy of proangiogenic gene therapy

Cardiology - Studies add new findings to cardiology body of knowledge

Cardiology - Study examined behavior of inositol 1,4,5-trisphosphate in heart and lung tissue

Cardiology - Study on stroke prevention in atrial fibrillation patients published in JAMA

Cardiovascular Disease - Domain antibody company joins European effort to discover new CVD treatments

Cardiovascular Disease Therapy - Novel EVA drug matrix enhances transdermal atenolol delivery

Cardiovascular Research - ETB receptors may have a role in regulating development of the ETA subtype

Cardiovascular Research - Study investigated effects of amiodarone on the vascular endothelin system

Cell Biology - Novel interferometry assay enables nanoscale molecular interaction analysis

Cell Biology - Scientists share new insights into muscle growth regulation

Cell Signaling - Inhibition of gallbladder contractility, role of ions clarified

Cholera Outbreak - Two fowl cholera outbreaks 8-years apart caused by same P. multocida clone

Chronic Hepatitis C - Triple combination therapy benefits previous hepatitis C non-responders

Chronic Liver Disease - Metallothionein gene therapy reverses liver fibrosis in mice

Chronic Liver Disease - Nonalcoholic fatty liver disease affects patients with hepatitis C adversely

Chronic Liver Disease - The incidence of nonalcoholic steatohepatitis is expected to rise in Japan

Chronic Liver Disease - Various factors influence chronic hepatitis C-related fibrosis progression

Chronic Pain - Dosing of phase I pharmacokinetic study for sufentanil patch product completed

Chronic Renal Failure - ET-1 production may be responsible for susceptibility to chronic renal failure

Clinical Trials - Company to start percutaneous heart valve clinical trial in U.S

Clinical Trials - Market research company releases study on per patient clinical trials cost

Clinical Trials - Results from ZEGERID Chewable Tablet trials announced

Clinical Trials - Results of phase 2 clinical trials with recombinant human thrombin announced

Clinical Trials - U.S. FDA requests additional information regarding company's clinical trials

Cloning - pTOC-T vector constructed by using GST-ParE toxin for direct cloning

Clostridium Vaccine - Immunization against Clostridium diarrhea and colitis reviewed

Collaborations - Agreement completed for rights to vaccines

Collaborations - Agreement signed for dopamine stabilizer technology

Collaborations - Agreement with U.K. Medical Research Council extended

Collaborations - Companies form alliance to provide services to clients

Collaborations - Companies sign alliance program for protein kinase target

Collaborations - Contract with Sunkist expanded to Hong Kong and Taiwan

Collaborations - Deal entered with Cilag for antibiotic

Collaborations - Hot mouse technology used for diabetes, obesity therapies

Collaborations - License agreement signed for novel diagnostic targets

Collaborations - Partnership formed so hospital can conduct clinical trials for drug company

Collaborations - Pharma firm announces licensing deal for transmucosal film technology

Collaborations - Pharmaceutical deal expanded for multiple developmental projects

Collaborations - Relationship with Eli Lilly renewed

Collaborations - Research collaboration agreement signed

Collaborations - Supply agreement signed for sale of needle-free systems

Collaborations - Tripos chosen as strategic chemistry partner in drug discovery

Colon Cancer - Ritonavir may curb colon carcinogenesis via apoptosis/inflammatory modulation

Colon Cancer - Studies describe new findings in colon cancer research

Colorectal Cancer - Drug company receives U.S. FDA approval for new Eloxatin formulation

Complementary & Alternative Medicine - Pu-erh tea analyzed, influence on physiological damage clarified

Complementary & Alternative Medicine - Radix astragali astragaloside IV studied, properties clarified

Complementary and Alternative Medicine - Psychoactive effects of guarana and ginseng evaluated

Compstatin - Compstatin analyzed, thermodynamics of interaction with complement revealed

Congestive Heart Failure - Thousands of heart failure deaths in U.K. are preventable, survey shows

Constipation - DFA III provided relief to patients with chronic constipation

Coronary Angioplasty - Combination of FXa and GPIIb/IIIa inhibitors safe and effective in mice

Coronary Heart Disease - Studies have investigated genetic variants and response to statin therapy

Coronary Stenting - Clopidogrel responsiveness after stent implantation highly variable

Creutzfeldt-Jakob Disease - Pharma company finds way to remove prions that cause mad cow in humans

Cystic Fibrosis -  Burkholderia cepacia increases mortality in cystic fibrosis

Cystic Fibrosis - CFTR biogenic intermediate studied, conditions of accumulation clarified

Cytomegalovirus Vaccines - Findings describe new data in cytomegalovirus vaccines research

DNA - DNA ligase analyzed, influence of replicative clamp loader revealed

Dendritic - DC-SIGN tetramers essential for high affinity interactions with HIV

Dendritic Cell Vaccine - Apoptosis of monocytes influences yield of dendritic cells

Dendritic Cell Vaccine - Method to monitor T cells after dendritic cell vaccination developed

Dendritic Cell Vaccine - Transcriptional regulation of dectin-2 promoter investigated

Dengue Fever - New findings in dengue fever described

Dengue Outbreak - Integrated therapeutic/public health response controls dengue outbreak

Dermatology - Adenovirus-based gene transfer prevents cancer in xeroderma pigmentosum models

Dermatology - Desmoglein 4 gene mutations correlate with hypotrichosis in lanceolate models

Dermatology - The loricrin gene is not involved in psoriasis susceptibility

Diabetes - Community-based diabetes plan of action introduced

Diabetes Complications - Amyloid peptide channels play role in diabetes complications

Diabetes Complications - Medications prevent diabetic kidney damage in rats

Diabetes Genomics and Genetics - Idd1 and Idd3 needed for development of type 1 diabetes

Diabetes Genomics and Genetics - Prevention of type 2 diabetes from viewpoint of genetics presented

Diabetes Genomics and Genetics - Risk of type 1 diabetes predicted from polymorphisms in candidate genes

Diabetes Pathogenesis - ATP synthase functions as fuel sensor in pancreatic beta cells

Diabetes Pathogenesis - Cytokines activate caspase-3 in insulinoma cells of diabetes-prone mice

Diabetes Pathogenesis - Findings advance knowledge in diabetes pathogenesis research

Diabetes Pathogenesis - IA-2 antibodies linked to increased risk of type 1 diabetes

Diabetes Pathogenesis - Impaired response to glucose load linked to low glucose storage

Diabetes Pathogenesis - Insulin secretion capacity in development of type 2 diabetes examined

Diabetes Pathogenesis - Protein kinase activation increases insulin secretion

Diabetes Pathogenesis - Recent findings in diabetes pathogenesis described

Diabetes Pathogenesis - Research add new data to diabetes pathogenesis body of knowledge

Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights

Diabetes Pathogenesis - Researchers describe findings in diabetes pathogenesis studies

Diabetes Pathogenesis - Researchers detail new studies and findings in the area of diabetes pathogenesis

Diabetes Pathogenesis - Studies advance knowledge in diabetes pathogenesis research

Diabetes Risk Factors - Breast-feeding protects glucose metabolism in young adult women

Diabetes Risk Factors - Hepatitis C virus infection triggers diabetes in liver graft recipients

Diabetes Surgery - Islet transplantation is realistic for type 1 diabetes treatment

Diabetes Therapy -  Commelina communis exhibits anti-hyperglycemic activity

Diabetes Therapy - Beta-cell cyclic adenosine monophosphate targeted diabetes therapy

Diabetes Therapy - Metformin not oxidized by free radicals in vivo

Diabetes Therapy - Molecular therapeutic target for type 2 diabetes reported

Diabetes Therapy - Preventing type 1 diabetes from viewpoint of beta-cell damage outlined

Diabetes Therapy - Sulfonylurea and non-sulfonylurea hypoglycemic agents reviewed

Diabetes Therapy - Sweet steviol glycoside derivatives effective against hyperglycemia

Diabetes Therapy - Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice

Diabetic Cardiomyopathy - Coronary artery surgery for diabetic patients outlined

Diabetic Foot Ulcers - U.S. FDA gives clearance to initiate diabetic foot ulcer trial

Diabetic Nephropathy - Advanced glycation end products important in diabetes complications

Diabetic Nephropathy - Erythropoietin inhibits endothelial cell apoptosis induced by glucose

Diabetic Nephropathy - Hypertriglyceridemia implicated in diabetic nephropathy

Diabetic Nephropathy - Researchers report details of new studies and findings in the area of diabetic nephropathy

Diabetic Neuropathy - Adipocytokines contribute to diabetic neuropathy

Diabetic Neuropathy - Brain metabolic alterations induced by hyperglycemia in type 1 diabetes

Diabetic Neuropathy - Diabetes induces expression of activating transcription factor 3

Diabetic Neuropathy - Kinin B-1 receptors expressed in spinal cord of diabetic rats

Diabetic Neuropathy - Methods to slow progression of diabetic neuropathy reviewed

Diabetic Neuropathy - Neural redox stress in type 2 diabetes and neuropathy reviewed

Diabetic Neuropathy - Reports advance knowledge in diabetic neuropathy research

Diabetic Neuropathy - Studies advance knowledge in diabetic neuropathy research

Diagnostics - LightCycler polymerase chain reaction can diagnose fungal infections

Diagnostics - Method to monitor zinc and calcium secretion from islet cells developed

Diagnostics - Researchers' data advance diagnostics research

Diagnostics - Stool-based DNA test is preferred over FOBT, colonoscopy for colorectal cancer

Diagnostics - Studies add new findings to diagnostics body of knowledge

Diagnostics - Transcriptional-based screens detect endothelial cell gene products

Diarrhea Vaccine - Antibody binding linked to activity of F4 fimbrial adhesin FaeG

Diet & Nutrition - New survey reveals challenges women face in consistent multi-vitamin routine

Diet & Nutrition - USU and HJF sign agreement for development of radiation protection compounds

Diet and Nutrition - Dietary fatty acids have dissimilar effects on genes in the rodent liver

Diet and Nutrition - Rice bran extract prevents elevation of plasma peroxylipid in diabetes

Disease Associations - Alpha-synuclein studied, influence of C-terminal domain on aggregation revealed

Disease Associations - Huntingtin interacting protein-1 related gene variants link to bipolar disorder

Disease Transmission - In Uganda, poverty is affecting AZT use among mothers

Drug Abuse - Methamphetamine-contaminated homes spur new push for federal research

Drug Abuse - Wyoming Senate panel approves meth bills

Drug Abuse - Zoners approve methadone dispensing on Bay Street in Vermont

Drug Delivery - Drug-delivery company retains OTC Financial Network

Drug Delivery - Introns are required for prolonged apolipoprotein A-I transfection

Drug Delivery - Lipid sponge phase as a transdermal drug delivery vehicle discussed

Drug Delivery - Market research company announces report on CNS diseases and drug delivery

Drug Delivery - New oral drug delivery technology improves effectiveness

Drug Delivery - Non-viral vectors make efficient antisense oligonucleotide delivery systems

Drug Delivery - Pharmaceutical company begins study of lingual spray of antiemetic agent

Drug Delivery - Pharmaceutical company offers ozone-friendly inhalation aerosol

Drug Delivery - Reports describe recent advances in drug delivery research

Drug Delivery - SLNs improved oral bioavailability of poorly soluble drugs

Drug Detection - Scientists make step forward in identifying drug doping

Drug Development - Additional ACT 1 clinical results reported

Drug Development - An oncolytic DNA-alkylating drug for treatment of solid tumors shows promise

Drug Development - Anti-IL-13 monoclonal antibody shows promise for asthma treatment

Drug Development - Bioactive peptide conjugates characterized using thioether linkages

Drug Development - Biopharmaceutical company announces new drug application

Drug Development - Blockbuster drugs with expiring patents gain new hope

Drug Development - Clinical trials for Emezine completed

Drug Development - Companies announce translational medicine strategic alliance

Drug Development - Diquafosol fails to demonstrate significant improvement in dry eye

Drug Development - Drug development company announces approval of new drug application

Drug Development - Emodepside has novel mode of anthelmintic activity

Drug Development - Functional interaction of CYP3A4 and P-glycoprotein warrants further research

Drug Development - International trial of two anti-HIV microbicides begins

Drug Development - Intrapleural gene therapy may cure human alpha1-antitrypsin deficiency

Drug Development - New generation reagent dispenser launched

Drug Development - Nutritional supplements marketer to introduce new product

Drug Development - Onconase clinical program expanded

Drug Development - Phenylalanine aminomutase analyzed and cloned

Drug Development - Protein microarray chips unearth new peptides with therapeutic potential

Drug Development - Regadenoson shows promise for myocardial perfusion imaging

Drug Development - Report details pharmaceutical brand team's road to success

Drug Development - Safety profile of naproxen detailed in U.S. FDA briefing document

Drug Development - Simulations Plus releases DDDPlus 1.0; new core product is first in industry

Drug Development - Spray-dried emulsions with drug dissolved in lipid characterized

Drug Development - Study outlines medical advances made due to biotechnology

Drug Development - Successful treatment reported with AT-1001 in rats with type I diabetes

Drug Development - Thallium flux assay identifies potassium channel modulators

Drug Development - The courage to change the rules: a proposal for an essential health R&D treaty

Drug Development - Thymalfasin may treat patients with chronic hepatitis B

Drug Development - Two major 8-prenylnaringenin metabolites are estrogenic in vitro

Drug Importation - Bill would let Texans buy prescriptions from Canada

Drug Importation - Minnesota governor, Pfizer executive defend drug importation

Drug Marketing - One-third of drug ads do not contain references supporting medical claims

Drug Marketing - Study reveals the huge influence of direct-to-consumer drug advertisements

Drug Metabolism - Novel CYP2A6 allele alters nicotine metabolism in black carriers

Drug Resistance -  C. albicans transcription factor Upc2p regulated drug resistance

Drug Resistance - Biliary cirrhosis studied, bezafibrate induction of multidrug resistance shown

Drug Safety - Drug safety, bioterror top new U.S. FDA chief's priority list

Drug Safety - FDA aims to improve drug safety monitoring

Drug Safety - Healthcare groups form Maryland Safety through e-prescribing STEP initiative

Drug Safety - New board will check on risks of drugs after government approval

Drug Safety - Pharmaceutical company surprised by Canada's suspension of treatment for ADHD

Ecology - Lack of permanent pools from intermittent streams reduced algal productivity

Embryogenesis - Mitochondrial SDHD gene required for early embryogenesis

Embryonic Stem Cell Research - ESC aggregation induces Nanog repression and primitive endoderm differentiation

Emerging Viral Infections - Emergent viral infections often due to crossing species barrier

Encephalitis - Gene dysregulation found in cortex of HIV encephalitis patients

End-Stage Kidney Disease - Renal transplants benefit familial Mediterranean fever amyloidosis patients

Endothelium - Uterine endothelium studied, relaxant effect of vasoactive polypeptide shown

Enterococcus Vaccine - Rationale for developing immunotherapy against enterococci presented

Environmental Health - Newly developed drinking-water biofilms favor growth of Nitrosomonas-type AOB

Enzymology - KRN633 eliminates angiogenic growth in solid tumors

Enzymology - Proteases mark the survival of node-negative breast cancer

Enzymology - Recent findings illuminate research in enzymology

Enzymology - Reports add new data to enzymology research

Epilepsy Therapy - Carbenoxolone has significant anticonvulsant effects in rats

Erectile Dysfunction - Erectile dysfunction common in Japanese men with type 2 diabetes

Esophageal Cancer - Esophageal adenocarcinoma cells treated with hemocyanin examined

Estrogen - Brain lipid peroxidation studied, protective effect of estrogen revealed

Ethics - How should health professionals communicate risk to patients?

Facilities - Lybradyn graduates from Chicago Technology Park, PharmaIn takes over lab space

Fatty Liver Disease - Weight loss surgeries can improve or correct liver diseases

Finance - Biopharma reports strong growth in consolidated operating income

Finance - Biopharmaceutical company reports 4Q, year-end 2004 financial results

Finance - Biopharmaceutical firm closes common stock offering

Finance - Biopharmaceutical firm files registration statement for IPO

Finance - Biopharmaceutical firm reports loss of $0.16 per share

Finance - Biotech company receives $8.3M in funding from private investors

Finance - Biotech firm reports income of $0.34 per share

Finance - Biotech reports 2004 revenues of $410.4 million

Finance - Biotechnology announces transition quarter financial results

Finance - Biotechnology company reports fiscal 2005 second quarter results

Finance - Biotechnology company reports fourth quarter, year-end financial results

Finance - Development and discovery company reports improved financial results

Finance - Drug development company files registration statement for public equity offering

Finance - Drug distributor declares 17th consecutive quarterly cash dividend

Finance - Drug- and diagnostic-discovery company reports $13.7M net loss for 2004

Finance - Healthcare Dialog parent company announces move to OTC Bulletin board

Finance - Healthcare products maker reports net income rise of 42%

Finance - IT company records profitable fiscal year with significant revenue, growth

Finance - Imaging company fails to meet full-year financial guidance

Finance - Information solutions provider reports 16% increase in fourth quarter revenues

Finance - Insulin-focused drug development company to exercise option to purchase shares

Finance - Medical waste management company reports fourth quarter, full year 2004 results

Finance - Nutrition bioscience company reports improved second quarter results

Finance - Oncology company reports loss of $0.01 per share

Finance - Oncology-focused biopharmaceutical company reports 4Q, fiscal 2004 results

Finance - Ophthalmology company's fourth quarter earnings rise 39.9%

Finance - Patient safety solutions provider announces fourth quarter and 2004 results

Finance - Personal care products company reports fourth quarter and year-end revenue

Finance - Pharmaceutical company announces 2004 financial results

Finance - Pharmaceutical company reports fourth quarter and full year 2004 results

Finance - Pharmaceutical company reports fourth quarter and year-end results

Finance - Pharmaceutical distributor reports 12% increase in sales

Finance - Pharmaceutical firm completes 1-for-5 reverse stock split

Finance - Pharmaceutical firm exercises over-allotment option by underwriters

Finance - Pharmaceutical firm prices follow-on stock offering

Finance - Pharmaceutical firm receives contract for 1.5M Ribavirin injections

Finance - Pharmaceutical firm reports 15.5% sales increase in fourth quarter

Finance - Pharmaceutical firm reports 213% increase in 2004 revenue

Finance - Pharmaceutical firm reports loss of $0.07 per share

Finance - Pharmaceutical firm reports placement of $170M

Finance - Pharmacogenomic-focused pharma reports increased revenues and losses in 2004

Finance - Small molecule therapeutics pharmaceutical company announces IPO

Finance - Technology company announces record financial results

Finance - Vaccine maker closes $3.77 million private equity financing

Food Safety - Acceptable daily intake evaluated

Food-Borne Pathogen -  C. jejuni survives on fresh produce long enough to pose consumer risk

Food-Borne Pathogen - Cold storage of grapefruit decreases survival of salmonellae

Fungal Infection - Phase 3 trial results evaluating anidulafungin for fungal infection announced

Gastric Infection - Review explores effect of H. pylori infection on micronutrient malnutrition

Gastroenterology - Angiogenin may influence the pathogenesis of inflammatory bowel disease

Gastroenterology - Studies advance knowledge in gastroenterology research

Gastroenterology - Vasoactive growth factors augment the healing of gastric ulcers

Gene Research - BLM gene interactions are detected in human cells

Gene Research - Gene profiles delineate the phenotypic character of human disease

Gene Research - Mammalian cortistatin is analogous to a non-mammalian somatostatin variant

Gene Research - Non-specific silencing complicates the use of small interfering RNA

Gene Research - Patients with polycythemia vera have rearrangements on chromsome 20

Generic Drugs - Company begins shipping Itraconazole capsules

Generic Drugs - Generic drug-focused company gets U.S. FDA approval of chewable antibiotic tabs

Generic Drugs - Pharma company cleared to market Megestrol Acetate Oral Suspension

Generic Drugs - Pharma company receives approval for Citalopram Hydrobromide tablets

Geriatrics - Humans display age and cataract-specific gene changes in the lens

Gestation - Dentate gyrus potentiation analyzed, role of infuled benzo(A)pyrene shown

Glioma Therapy - Selective estrogen receptor modulators induce glioma cell apoptosis

Glycemic Control - Glucose control in diabetes reviewed

Glycoprotein - P-glycoprotein studied, role in brain uptake of dextromethorphan revealed

Gynecology - Atrasentan augments therapies targeting ovarian carcinoma

Gynecology - Endothelin receptor blockade may eliminate COX-2-associated ovarian cancer

HIV/AIDS Diagnostics - Diagnosis not always self-evident in early stage of HIV-associated wasting

HIV/AIDS Diagnostics - HIV antibody/antigen assays perform better than antibody-only assays

HIV/AIDS Diagnostics - Research shows HIV screening is cost effective

HIV/AIDS Drug Development - Active site conformation used for HIV-1 integrase inhibitor design

HIV/AIDS Drug Development - Hops Humulus lupulus extract inhibits HIV replication

HIV/AIDS Drug Development - Thia-DCK analogs inhibit HIV-1

HIV/AIDS Drug Monitoring - Intracellular pharmacology of protease inhibitors improves therapeutic efficacy

HIV/AIDS Healthcare - Over-emphasis on food aid at expense of public health interventions in S Africa

HIV/AIDS Lipodystrophy - IGFBP-3 protease significant regulator of bioactive IGF-I in HIV-lipodystrophy

HIV/AIDS Opportunistic Infection - C-18 mutations critical for CCR5-binding/HIV-1 fusion inhibition

HIV/AIDS Pathogeneis - HIV-1 envelope facilitates contagious apoptosis

HIV/AIDS Pathogenesis - HIV-1 can dysregulate CD4+ T cells that express CXCR4

HIV/AIDS Pathogenesis - Plasma IL-18 associated with viral load/disease progression in HIV-1-infection

HIV/AIDS Pathogenesis - SOCS box in HIV-1 Vif that mediates its interaction with ElonginC characterized

HIV/AIDS Pathogenesis - T-cell activation leads to poor activation of HIV-1 clade E LTR

HIV/AIDS Pathogenesis - Thioester stability does not correlate significantly with anti-HIV-1 activity

HIV/AIDS Prevention - Chinese rural-to-urban migrants participate in AIDS prevention programs

HIV/AIDS Prevention - School-based intervention for HIV/AIDS prevention has positive impact

HIV/AIDS Research - APOBEC3B and APOBEC3C are potent inhibitors of SIV replication

HIV/AIDS Research - Cellular adhesion to VCAM-1 mediated by VLA-4 is suppressed after treatment

HIV/AIDS Research - Evans Blue inhibits NF-kappaB-DNA binding

HIV/AIDS Research - HIV LTR-dependent Bax expression selectively induces apoptosis in Tat+ cells

HIV/AIDS Research - SOCS-box phosphorylation regulates assembly of HIV-1 Vif-Cul5 complex

HIV/AIDS Screening - Coalition on HIV/AIDS applauds new study recommendation to test all adults

HIV/AIDS Therapy - Difference in median CD4 increase in HIV subtype B vs. non-B after PI therapy

HIV/AIDS Therapy - Drugs to inhibit drug-resistant HIV reverse transcriptases developed

HIV/AIDS Therapy - Entry inhibitor BMS-378806 may have reduced efficacy against non-B HIV-1

HIV/AIDS Therapy - HIV patients living longer with better drugs

HIV/AIDS Therapy - New research in the area of HIV/AIDS therapy detailed

HIV/AIDS Therapy - Studies describe new findings in HIV/AIDS therapy research

HIV/AIDS Treatment - Boston doctors report growing resistance to HIV drugs

HIV/AIDS Treatment - Time delay model shows possible effects of HAART on HIV dynamics

HIV/AIDS Vaccine - Advances in diagnosis and treatment of acute HIV-1 infection reviewed

HIV/AIDS Vaccine - Collaborators expand phase 1 clinical trial of HIV/AIDS vaccine program to India

HIV/AIDS Vaccine - Conformational changes during T cell receptor engagement reported

HIV/AIDS Vaccine - HIV induces and maintains suppression of thymocyte proliferation

HIV/AIDS Vaccine - Rise in immune activation linked to alterations in immune function

HIV/AIDS Vaccine - T cell receptor recognition motifs govern immune escape in SIV

HIV/AIDS Vaccines - Recent findings in HIV/AIDS vaccines described

HIV/AIDS Wasting - HIV-associated wasting exacerbated by reduced food intake/GI dysfunction

HIV/AIDS-Related Aspergillosis - Chest film plus clinical data improves IPA diagnosis in HIV patients

HIV/AIDS-Related Cryptococcosis - HIV infection is the most important risk factor for cryptococcosis

HIV/AIDS-Related Encephalitis - CD163 identifies a unique population of ramified microglia in HIV encephalitis

HIV/AIDS-Related Infection - Strong correlation between eosinophilia and helminthiasis in HIV infection

HTLV-1 Infection - Mathematical model studies the dynamics of HIV-1 infection of CD4+ cells

Haemophilus Vaccine - Antibodies against Haemophilus parasuis characterized

Hand Washing - Hand washing compliance in food service dependent on knowledge of supervisor

Head and Neck Cancer - Liposomal lurtotecan has limited efficacy in advanced SCCHN

Head and Neck Cancer - U.S. FDA grants orphan drug designation for Proxinium

Healthcare Coverage - Doctor helping other doctors reduces drug costs for poor

Healthcare Coverage - Equitable allocation of antiretrovirals sought

Healthcare Coverage - Pennsylvania budget preserves protection for vulnerable citizens

Heart Failure - Excretory contribution of ETB receptor was attenuated in congestive HF

Heart Failure - Heart failure society kicks off awareness campaign

Heart Failure - Thyroid hormone receptor-binding compound may be adjunct to standard HF therapy

Heart Failure - U.S. FDA accepts NDA resubmission for BiDil

Hematology - Hepatitis C therapy alters hematological parameters in HIV-coinfected patients

Hematology - Researchers detail new studies and findings in the area of hematology

Hematology - Researchers provide details of new studies and findings in the area of hematology

Hematology - Tunisian patients harbor a common mutation on the hemochromatosis gene

Hematopoiesis - Panorama of lineage-specific transcription occurs during hematopoiesis

Hemovigilance - Norway has strict rules regarding hemovigilance for transfusion

Heparin - Practical use of generic low-molecular-weight heparins reviewed

Hepatitis B Vaccine - European approval announced for Fendrix, GSK's hepatitis B vaccine

Hepatitis C - Liver-targeted drug delivery article published in journal

Hepatitis C Therapy - Enrollment, randomization, dosing completed in Albuferon phase II trial

Hereditary Angioedema - Companies sign manufacturing agreement for recombinant human C1 inhibitor

Histamine - Histamine receptor studied, nature of phosphorylations clarified in intact cells

Hormone Replacement Therapy - Changing chemistry helps explain estrogen threat to the heart

Hormone Replacement Therapy - Research sheds light on why estrogens produce unintended results in women

Huntington Disease - Intrabodies confront dysfunctional protein activity

Hyperglycemia - Postprandial hyperglycemia in type 2 diabetes reviewed

Hyperparathyroidism - Hyperparathyroidism studied, oxacalcitriol dose-response revealed

Hypertension - COX-2 inhibitors associated with blood pressure elevation

Hypertension - Microdosing studies completed for hypertension treatment

Hypoglycemia - Consequences of nocturnal hypoglycemia in type 1 diabetes reviewed

Hypoglycemia - Identification and impact of asymptomatic hypoglycemia reviewed

Hypothyroidism - Pharma company introduces a new thyroid replacement therapy

Imidazole - Formamidopyrimidine-DNA glycosylase studied, active site behavior clarified

Immunology - CD4 mimicry by anti-idiotypic antibody based on conformational epitope

Immunology - Dr. Thomas F. Gajewski joins clinical advisory board

Immunology - Heterogeneity of Ag-specific CD4 cell responses regulated by Ag exposure/Ag load

Immunology - Innate immune responses during infection reviewed

Immunology - Researchers' work adds to immunology body of knowledge

Immunotherapy - Interleukins and gene corrected bone marrow cells remedy immunodeficiency

Immunotherapy - TNF-alpha targeted as a key disease molecule

Infection Control - Nebulized saline treatment reduces bioaerosol particle exhalation

Infectious Bronchitis Vaccine - H strain of avian infectious bronchitis virus as vaccine reviewed

Infectious Pancreatic Necrosis Virus - Infectious pancreatic necrosis virus strains characterized

Inflammation - Beta-adrenergic receptor studied, neutrophil regulation clarified

Inflammatory Bowel Disease - Antioxidant PDE4 inhibitor tetomilast shows promise for treatment

Inflammatory Disease - Alpha1-antitrypsin gene deficiency in mice resembles human fetal disease

Inflammatory Disease - Transglutaminase 2 induces NF-kappa B activation via BV-2 microglia pathway

Influenza - Educational action needed to curb flu outbreaks in the workplace, survey shows

Influenza Vaccine - Flu shots don't save lives in elderly, study suggests

Influenza Vaccine - Prevention of lower respiratory tract infections with vaccines reviewed

Influenza Vaccine - siRNAs show promise for treatment of influenza

Influenza Vaccines - New findings in influenza vaccines described

Influenza Virus - Genomic segments of influenza B virus strains mapped

Information Technology - Center for Evidence Based Pharmacy Practice pharmacy cost control toolkit

Information Technology - Drug company announces individual bar coding on all insulin vials

Information Technology - GNSI partners to create single point of entry for e-submissions to the FDA

Information Technology - Hospital prepares to implement wireless barcode medication charting

Information Technology - Library group urges researchers to comply with U.S. NIH public access policy

Information Technology - New method released to improve the management of opinion leader relationships

Information Technology - Pennsylvania hospital group upgrades to enterprise clinical software system

Information Technology - Telemedicine company forms alliance to promote blood monitoring system

Information Technology - U of Chicago Comer Children's Hospital selects inventory management system

Information Technology - University of Rochester Medical Center extends IT solution system-wide

Insulin - Insulin isotherms in ethanol-water reversed phase systems presented

Insulin Delivery - Recent advances in inhaled insulin therapy to treat diabetes reviewed

Insulin Resistance - Pro12Ala polymorphism of PPAR-gamma gene linked to insulin resistance

Insulin Therapy - Company reports preliminary results of a phase IIb clinical study of Oral-lyn

Kaposi Sarcoma-Associated Herpesvirus - E2-binding C4HC3-type RING domain identified in KSHV K3N-terminal domain

Kaposi Sarcoma-Associated Herpesvirus - New research in the area of kaposi sarcoma-associated herpesvirus detailed

Legal Issues - Jury finds 15-year-old boy guilty in Zoloft defense trial; 30 year sentence

Legal Issues - St. Francis Hospital settles vaccine fraud case

Legal Issues - Wrongful death lawsuit filed against makers of children's ibuprofen product

Leishmaniasis Therapy - Effects of renal impairment on antimony pharmacokinetics determined

Leukemia - A cargo peptide transporter system halts aggressive leukemia and lymphoma

Leukemia - Agreement with U.S. FDA on protocol assessment of leukemia treatment announced

Leukemia - Vaccine may complement conventional treatment for chronic leukemia

Lipotoxicity - Lipotoxicity is an imbalance between lipogenesis de novo & fatty acid oxidation

Liver Cancer - Nobiletin inhibits hepatocarcinoma cell proliferation in vitro

Liver Cancer - Researchers provide details of new studies and findings in the area of liver cancer

Malaria - Histidine-rich protein-based malaria drug assay developed, field use reported

Malaria - Incidence data over 30 years reveals trends in Malaria transmission

Malaria - New data illuminates research in malaria

Malaria - Simple treatment could prevent many child malaria deaths

Malaria Vaccine - Alanine-rich repeats are intact in Plasmodium falciparum MSP3

Malaria Vaccine - Allelic dimorphism found in surface protein of Plasmodium vivax

Malaria Vaccine - Sequence diversity of P. falciparum merozoite protein reported

Malaria Vaccines - Researchers describe findings in malaria vaccines studies

Malaria Vaccines - Studies advance knowledge in malaria vaccines research

Malignant Melanoma - Viragen files to expand cancer approval for Multiferon in Sweden

Marketing - Companies are embracing pharma sales technology

Melanoma - Microtubule-dependent MMP-2/MMP-9 exocytosis needed for cell invasion

Melanoma Vaccines - Data advance knowledge in melanoma vaccines research

Melioidosis Vaccine - Subunit vaccines against experimental melioidosis evaluated

Membrane Topology - Acid-sensing ion channel 2a analyzed, membrane topology clarified

Memory - Water maze learning in hyperglycemic-hyperinsulinemic rats studied

Meningococcus Vaccine - Public health management in invasive meningococcal diseases reviewed

Mental Health - Detailed measurements clarify the genomic etiology of bipolar disorder

Mental Health - Hyperactive cannabinoid systems may be involved in schizophrenia etiology

Mergers & Acquisitions - Antisoma completes acquisition of Aptamera

Mergers & Acquisitions - Aptamera's shareholders approve acquisition by Antisoma

Mergers & Acquisitions - Canadian business Multichem acquired for CDN $23.8M

Mergers & Acquisitions - Cancer treatment systems company to be acquired by Cytyc Corporation

Mergers & Acquisitions - Cytyc expands women's health presence with acquisition

Mergers & Acquisitions - Integrated drug development company acquires Scantox

Mergers & Acquisitions - Japanese pharmaceutical company to merge Syrrx into Takeda Group

Mergers & Acquisitions - Pharmaceutical and chemical company acquires business unit of Avecia

Mergers & Acquisitions - Pharmaceutical services company completes sale of drug delivery business

Mesothelioma - Petition urges Congress to fund mesothelioma research

Metabolic Syndrome - Metabolic syndrome drug pipeline report announced

Metabolic Syndrome - Researchers' data advance metabolic syndrome research

Metabolic Syndrome - Researchers' work adds to metabolic syndrome body of knowledge

Metapneumovirus Vaccine - In ovo vaccination with avian metapneumovirus vaccine reported

Methicillin-Resistant Staphylococcus Aureus - Gentamicin-susceptible MRSA clone in Rio de Janeiro resembles NY/Japanese clone

Methicillin-Resistant Staphylococcus Aureus - Oils effect antibacterial against epidemic methicillin-resistant S. aureus

Microbicidal Vaginal Gel - Spread of microbicidal vaginal gel dependent on time and volume

Mosquito-Borne Disease - Mosquito densoviruses used to control Aedes aegypti mosquitoes

Multiple Sclerosis - Clinical study of mitoxantrone is in progress to assess long-term safety

Multiple Sclerosis - Current approved options for treating patients with multiple sclerosis

Murine Mesothelioma - Pharma company begins preclinical study of murine mesothelioma treatment

Mutagenesis - Aipl1-deficient mice model a disorder that causes pediatric blindness

Mycoplasma - PCR method for mycoplasma testing of cell cultures developed

Mycoplasma Infection - Bovine pinkeye outbreak associated with mixed mycoplasma infection

Natural Products - ESPS elevated soybean production

Nephrology - Scientists identify potential therapy for kidney failure

Nephrology - Sp1 activation is crucial for claudin-19 gene expression in kidney cells

Neural Stem Cell Research - Cell-cell & cell-extracellular matrix contacts essential for NSC maintenance

Neural Stem Cell Research - ESC-derived neurons response in a manner similar to primary central neurons

Neural Stem Cell Research - Endoneurial fibroblasts are derived from neural crest

Neural Stem Cell Research - Hes genes regulate nervous system by controlling timing of NSC differentiation

Neural Stem Cell Research - Oct-3/4 repression accelerates differentiation of neural progenitor cells

Neural Stem Cell Research - Oligodendrocyte conversion to NSLC depends on progressive chromatin remodeling

Neural Stem Cell Research - Pergolide protects against levodopa-induced cytotoxicity of neural stem cells

Neural Stem Cell Research - Programmed cell death of adult-generated hippocampal neurons mediated by Bax

Neural Stem Cell Research - Vax1 potent regulator of subventricular zone organization and NSC proliferation

Neurodegeneration - Genetic fingerprints exemplify type 2 Gaucher disease

Neurodegeneration - Reports describe recent advances in neurodegeneration research

Neurology - Nurr1 expression studied in the brain, effect of chronic lithium revealed

Neuroscience - Brain synapse formation linked to proteins

Neuroscience - Mitoxantrone should be restricted to certain multiple sclerosis patients

Neuroscience - Study explored changes resulting from long-term endothelin antagonism

Neuroscience - VEGF levels rise when peritumoral edema accompanies intracranial meningiomas

Norovirus - Genogroup I/II noroviruses detected in stool samples by real-time RT-PCR

Nosocomial Infections - Genomic factors dominate Pseudomonas aeruginosa in cystic fibrosis patients

Nuclear Membrane - Nuclear pore-directed transport of proteins studied, conditions clarified

Obesity - Biotech company focused on metabolic disorders obtains license to obesity genes

Obesity - Genetics factors partly responsible for middle-age spread in middle-class males

Obesity Pathogenesis - Researchers publish new studies and findings in the area of obesity pathogenesis

Obesity and Diabetes - Findings advance knowledge in obesity and diabetes research

Obesity and Diabetes - Obesity, bariatric surgery, and type 2 diabetes reviewed

Obesity and Diabetes - Protein kinase C interactions in adipocytes regulate glucose uptake

Obesity and Diabetes - Signal pathway regulating plasminogen activator inhibitor identified

Obstetrics - High maternal hepatitis C virus levels cause transmission to fetuses

Oncology - Angiogenic protein levels differentiate malignant and nonmalignant ascites

Oncology - Antisense molecules targeting alpha folate receptor hinder breast cancer cells

Oncology - Data advance knowledge in oncology research

Oncology - Low platelet counts denote multicentricity in HCV-related liver cancer

Oncology - New data illuminates research in oncology

Oncology - Pro-apoptotic gene therapy destroys prostate cancer

Oncology - Recent findings illuminate research in oncology

Oncology - Researchers publish new studies and findings in the area of oncology

Oncology - Studies add new findings to oncology body of knowledge

Oncology - Systems biology-tech firm gets U.S. NCI grant for analysis of cancer networks

Ophthalmology - Endothelin-1 eyedrops produce retinal vasculopathy models

Osteoporosis - Calcitonin effectively decreases bone resorption in at-risk elderly women

Osteoporosis - Calcitriol improves streptozotocin-induced diabetes, recovers BMD in rats

Osteoporosis - Data presented on 5 years of treatment with risedronate

Osteoporosis - Pharma company adds time to prepare new drug application for osteoporosis drug

Ovarian Cancer - Murine models of early and late stage disease help evaluate therapeutics

Ovarian Cancer - Phase III clinical trial on monoclonal antibody is enrolling patients

Ovarian Cancer - Researchers evaluating new therapy for advanced ovarian cancer

Ovarian Cancer - U.S. FDA grants approval to ovarian cancer treatment following data submission

Pain Management - Healthcare company introduces topical system to reduce needlestick pain

Pain Management - New study links Vioxx, Celebrex, Bextra to increased cardiovascular risk

Pain Management - Painkiller sales decline shows more pain patients may be suffering

Pain Medicine - COX-2 product offers good and bad news in "test tube" strokes

Pain Medicine - Still more to learn before treating rotator cuff injuries

Pain Medicine - Two products of diclofenac sodium suppositories compared

Pain Medicine - Vioxx nearly doubled cardiovascular risks in cancer prevention study

Pancreatic Cancer - BIA shown as prognostic indicator in pancreatic cancer

Pancreatic Cancer - Novel putative protein biomarkers and therapeutic targets identified

Pancreatic Cancer - Pancreatic cancer therapy clinical trial results announced

Pancreatic Cancer - Recent findings in pancreatic cancer provide new insights

Pancreatic Cancer - Safety board gives go-ahead for ongoing trial of pancreatic cancer treatment

Pancreatic Islets - Adenoviral overexpression protects pancreatic islets from oxidation

Parasitology - Environment and parasite genetics dictate murine resistance to malaria microbes

Parkinson Disease - Pharmaceutical company moves Parkinson medication into phase III development

Patents - European patent office issues allowance for paclitaxel drug in Europe until 2017

Patient Education - Pictograms do not improve children's grasp of medicine information

Pediatric Apheresis - Technical risks considered in pediatric apheresis due to size of patient/donor

Pediatric Healthcare - Expensive drugs for rare illnesses increase pinch for state aid

Pediatric Healthcare - Schools responding to increasing use of hyperactivity drug

Pediatric Healthcare - Study supports benefits of giving dehydrated children fluids by mouth

Personnel - Australian oncology firm announces change in board of directors

Personnel - Biological company announces new chairman of the board

Personnel - Biopharma company elects president and chief operating officer

Personnel - Biopharmaceutical company adds two virologists to its scientific resource board

Personnel - Bioprocessing companies announce leadership team

Personnel - Biotech executive joins new biopharmaceutical company

Personnel - Biotechnology pharmaceutical company announces two senior management changes

Personnel - Bush fills long-standing vacancy at FDA with Univ. of Georgia graduate

Personnel - Dale A. Sander joins protein-therapeutics company as CFO and senior VP

Personnel - David A. Rutledge named CFO at nonprofit research organization

Personnel - Diagnostics company names Michael Silver VP of clinical research

Personnel - Dr. Joseph Rubinfeld resigns from board of Nipent maker

Personnel - Dr. Rafik H. Bishara joins cold-chain management company

Personnel - Drug discovery chemistry company promotes Mark Allen to senior vice president

Personnel - Drugmaker names Michael J. Gast, MD, PhD, as chief medical officer

Personnel - Gary Ingenito named senior VP of pharmacotherapeutics company

Personnel - Genomics company announces new board member

Personnel - Gustavsson to chair biopharmaceutical firm's advisory board

Personnel - Health care company mourns death of former executive

Personnel - Health technology company appoints executive vice president, general manager

Personnel - Herbert H. Mertens named VP, sales and marketing, of Powerlink maker

Personnel - IVAX announces new board of directors member

Personnel - Lifesciences organization announces new appointment to advisory board

Personnel - Medical device company names chief financial officer

Personnel - Metabolic profiling services hires new vice president of sales and marketing

Personnel - Michael W. Aguiar named chief financial officer by biopharmaceutical company

Personnel - Pharma company names chief business officer

Personnel - Pharma company president elected to California Healthcare Institute Board

Personnel - Pharmaceutical company announces new board member

Personnel - Pharmaceutical company appoints chief medical officer

Personnel - Pharmaceutical company appoints member of board of directors

Personnel - Pharmaceutical company names key outside director

Personnel - Pharmaceutical firm appoints Williams as VP, head of corporate development

Personnel - Pharmaceutical firm strengthens management team with new VP

Personnel - Protein-focused biopharmaceutical company appoints Theresa Heggie as GM, Europe

Personnel - Protein-focused biotech company names Dartmouth cancer researcher to board

Personnel - Regenerative medicine company announces executive appointments

Personnel - Robert E. Knowling, Jr. appointed chair of immune-based therapy company board

Personnel - Therapeutics company announces appointment of new board member

Personnel - Yong-Jian Geng, MD, PhD, joins advisory board of drug development company

Personnel - qNPA technology company names two researchers to scientific advisory board

Pertussis Vaccine - Antigenic variation linked to B. pertussis electrophoresis profiles

Pestivirus Vaccine - Phylogenetic analysis of bovine pestiviruses performed

Pharmaceutical Research - Bioanalytical company U.S. FDA continue talks regarding bioequivalence studies

Pharmaceutical Research - Studies show risk for serious side effects in drug combinations

Philanthropy - ExxonMobil announces more than $5 million in grants for malaria

Prodrug - Acyclovir studied, bioavailability and transport in Caco-2 cells revealed

Product Licensing - Fujisawa obtains the worldwide rights to antipsychotic agent

Product Licensing - Marketing agreement forged for treatment of dyslipidemia

Product Licensing - Ophthalmic company obtains rights to develop new treatment for dry eye

Promyelocytic Leukemia - Dominant molecular signatures of PML influenced by independent events

Prostate Cancer - IBt announces renewal of European distribution agreement

Protein Folding - Lysozyme refolding analyzed, influence of macromolecular crowding clarified

Protein Regulation - Mechanical stretch upholds the angiogenic potential of CCN1

Protein Signal - Signal transduction modulation through PrPc linked to lipid raft incorporation

Proteomics - Core protein processing varies with hepatitis C virus genotype

Proteomics - Findings advance knowledge in proteomics research

Proteomics - Human PTIP maintains genome stability

Proteomics - Ligand binding assay incorporated into centrifugal microfluidics platform

Proteomics - Researchers' work adds to proteomics body of knowledge

Proteomics - Study examined effects of ET-1 and aldosterone on COX-2 gene expression

Pseudomonas Vaccine - Vaccine against Pseudomonas aeruginosa infection developed

Psoriasis - Biopharmaceutical company achieves target enrollment for psoriasis trial

Psychopharmacology - Ketoconazole synergizes with allopregnanolone treatments in rat study

Pulmonary Arterial Hypertension - Encysive Pharma shares surge as Thelin drug meets late-stage study

Pulmonary Medicine - MMP1 gene polymorphism associates with chronic obstructive pulmonary disease

Pulmonary Medicine - Survivin and p53 modulate the influence of quercetin on lung cancer cells

Pulmonary Medicine - The role genetics plays in panbronchiolitis susceptibility is questionable

RNA Research - Potelligent RNAi launched for RNA research

RNA Research - Progress reported on infectious disease program using Neugene antisense drugs

Receptor Studies - ET-1 antinociceptive effect involved descending pain inhibitory system

Receptor Studies - Novel system improves cannabinoid receptor 2 purification

Receptor Studies - VPAC1 , VPAC2 , and PAC1 receptors in human tissues identified

Renal Anemia - Epoetin therapy during hemodialysis alters erythrocyte metabolism

Respiratory Medicine - Ultrasonic nebulization supports polyplex stability during aerosolization

Restless Legs Syndrome - Phase 2b clinical trial of drug for treatment of restless legs syndrome begins

Retinoblastoma - Study demonstrates effectiveness of drug in treatment of retinoblastoma

Rheumatology - Impaired vessel growth causes the vascular symptoms of systemic sclerosis

Rotavirus Vaccine - Rotavirus vaccines to prevent diarrhea in children reviewed

Salmonella Bacteremia - Risk factors identified for developing nontyphoid Salmonella bacteremia

Salmonella Enterica - Virulence gene expression profiles differ with type of S. enterica strain

Salmonella Vaccine - Method to estimate endotoxin in Salmonella vaccine developed

Salmonellosis - Prolonged incubation period of salmonellosis associated with low bacterial doses

Scedosporiosis - Liposomal amphotericin B effective in murine model

Schistosomiasis - Synergy increases granulomas induced by Schistosoma protein

Schistosomiasis Vaccine - Artemether triggers resistance against Schistosoma re-infection

Schizophrenia - Clinical data released for secretin in refractory schizophrenia

Severe Acute Respiratory Syndrome - Pharmaceutical company receives SARS vaccine funding

Sexual & Reproductive Health - Biopharmaceutical company reports results of female sexual dysfunction study

Sexual & Reproductive Health - Clinical trial: Testosterone spray enhances female sexual desire

Sexual & Reproductive Health - Immediate access to antibiotics stems spread of sexually transmitted diseases

Shellfish Poisoning - Low risk of azaspiracid poisoning from shellfish harvested at Portuguese coast

Staphylococcus Vaccine - Glucosamine polysaccharide shows promise for staphylococcal vaccine

Staphylococcus Vaccine - Humanized antibody targeting Staphylococcus aureus developed

Statins - More evidence presented on APOE genotype and baseline CRP relationship

Stem Cell Research - CD34+ cells generate phenotypically new monocyte in culture

Stem Cell Research - Early human T/NK/B progenitors cells in cord blood molecularly characterized

Stem Cell Research - G-CSF is best cytokine for PBSC mobilization despite efficacy/safety debate

Stem Cell Research - IL-16 plus thrombopoietin induces generation of tolerogenic dendritic cells

Stem Cell Research - IREM-1 is an inhibitory receptor expressed by myeloid cells

Stem Cell Research - Identifying adult SCs essential for understanding its dynamics during adult life

Stem Cell Research - MSCs acquire tissue specific morphology under minimal injury conditions

Stem Cell Research - PU.1 necessary for maintenance of fetal liver hematopoietic stem cells

Stem Cell Research - Phosphophoryn regulates MSC gene expression via integrin/MAPK signaling pathway

Stem Cell Research - Stop-EGFP mouse used to investigate clonal cell lineages

Stem Cell Transplantation - HLA mismatched SCT based on feto-maternal tolerance alternative to matched donor

Stem Cell Transplantation - Surrogate markers and agents for PBSC mobilization improve collection efficiency

Stem Cells Research - Epidermal stem cells regenerate a long-lasting epidermis

Stem Cells Research - Stem cells may be target cells in development of cancer

Streptococcus Vaccine - Host-pathogen interactions of Streptococcus pyogenes reviewed

Stroke - Confirmatory study of desmoteplase begins

Stroke - Stroke diagnosis, pharma, devices, and surgical intervention market researched

Systemic Lupus Erythematosus - Peptide ameliorates lupus manifestations

Thioredoxin -  Dictyostelium discoideum thioredocin targets shown, properties revealed

Thioredoxin Reductase - Thioredoxin reductase studied, role in growth of lens epithelial cells revealed

Thrombosis - Clot-busting drugs may help detect potentially deadly leg clots

Thrombosis Therapy - Perceptions of generic warfarin by anticoagulation providers examined

Tissue Engineering - Acellular matrix possible for functional reconstruction the urogenital tract

Tissue Engineering - Biodegradable scaffolds used for reconstruction of urethral/ureteral tissue

Tissue Engineering - Biological vascularized matrix solves problem of perfusion in tissue engineering

Tissue Engineering - Nano-fibrous scaffolds developed for tissue engineering

Tissue Engineering - Optimized condition determined for creation of urothelium for large surfaces

Tissue Engineering - Ultrasound intensity effects collagen fiber formation for bone mineralization

Tobacco Use - Transcriptional effects of nicotine determined in five brain regions

Toxicology - Chitosan derivatives staunch genotoxicity

Toxicology - Dioxin has weak estrogenic activity in the uterus

Toxicology - Exposure to hydrocortisone impair fertility in prenatal female rats

Transdermal Drug Delivery - Limonene enhances skin permeability of nimodipine in vitro

Transdermal Drug Delivery - Magnolia lily oil improves skin permeation of theophylline and cianidanol

Transplant Medicine - Adefovir resolves drug-resistant hepatitis B after liver transplantation

Transplant Medicine - Adult living donor liver grafts meet the demand for donated organs

Transplant Medicine - Gene profiles show fractalkine plays a role in kidney allograft rejection

Transplant Medicine - Preoperative prophylaxis aids patients given HBV-related liver transplants

Tuberculosis Vaccine - DNA vaccine protects mice against primary TB infection

Tuberculosis Vaccines - Researchers' findings advance tuberculosis vaccines research

Type 1 Diabetes Research - Company announces public release of phase IIa data on Basulin

Urinary Incontinence - Transdermal oxybutynin patch developed

Urinary Tract Infection - Progress toward a new remedy for UTI?

Vaccine Development - Host cell-pathogen interfaces reviewed

Vaccine Development - MHC affects genetic resistance to infectious bronchitis vaccines

Vaccine Efficacy - scFv reactivity enhanced after mixing with anti-tag monoclonal antibody

Vaccine Safety - Fatalities following allergen immunotherapy reported

Vaccines Adjuvant - New findings in vaccines adjuvant described

Vaccines Development - New findings in the area of vaccines development described

Vaccinia Virus - Exit of vaccinia virus from infected cells reviewed

Varicella-Zoster Vaccine - Genetic profile of Oka varicella vaccine virus variant presented

Vector Development - Low-pressure chromatography synthesizes PEG-peptides for gene delivery

Venous Thrombosis - Pharmaceutical company initiates clinical trial for oral anticoagulant

Vibrio Cholerae -  Vibrio cholerae O1 is a resident of Argentinean waters

Viremia - Most episodes of transient HIV "blips" not clinically significant

Virology - Bone marrow transplantation raises the risk for viral reactivation

Virology - Data advance knowledge in virology research

Virology - Hepatitis B virus genotype D backs aggressive liver disease

Virology - Oncolytic adenovirus selects hypoxic tumor cells for destruction

Virology - Recent findings illuminate research in virology

Virology - Recombinant adenoviruses initiate complement activation

Virology - Recombinant baculovirus vectors could transport genes to the nervous system

Virology - Reports add new data to virology research

Virology - Reports advance knowledge in virology research

Virology - Retroviruses transduce embryonic stem cell-derived hematopoietic progenitors

Yellow Fever Vaccine - International standard for yellow fever vaccine established

Return to Top of Page

NewsRx is Social

Follow us on your favorite social network by clicking on a button below:

Follow NewsRx on Twitter

NewsRx on Facebook

Awards

eHealthcare Leadership 2011 Winner
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

  • Google 2010 PageRank: #2 Among Top Health News and Media Publications
  • Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
  • Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
  • Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
NewsRx on Facebook