Heart Failure
Study investigated effects of SCH00013 on Ca2+-induced force generation
Published in Drug Week, April 8th, 2005
According to a study from Japan, "We investigated the effects of the agent SCH00013 on Ca2+-induced force generation in rabbit skinned cardiac muscle fibers and in vivo cardiac function in high-pacing-induced heart failure dogs."
N. Tadano and colleagues of Kyushu University reported, "The Ca2+-induced force generation in skinned cardiac muscle fibers was determined at pH 6.2 - 7.4, and SCH00013 was found to have a significant Ca2+ sensitizing effect at pH 7.2 to 7.4. There...
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Source: Drug Week (2005-04-08)
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