Drug Week
Susan Hasty, Publisher
Table of Contents . . . April 15th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Cancer Therapy - Study shows clear improvement in survival demonstrated for glioblastoma
Drug Development - Positive results from phase III trial of MNTX in opioid-induced constipation
Drug Interactions - Interaction between herbal medicine and CV drugs is an important safety issue
Glioblastoma Multiforme - FDA approves TEMODAR (temozolomide) for patients with newly diagnosed GBM
Vaccine Development - Telomerase vaccine study results in metastatic prostate cancer patients released
Actinic Keratosis - Clinical trial for non-melanoma skin cancer and actinic kertosis initiated
Adult T-Cell Leukemia - TSLC1 overexpression may be a molecular marker for acute-type ATL
Adverse Drug Reaction - Anticonvulsant drug poses greater birth-defect risk than suspected
Adverse Drug Reaction - Studies report mixed results on epilepsy drugs and birth defects
Allergy & Immunology - Chinese health authorities approve application for allergy vaccine
Breast Cancer - Researchers detail new studies and findings in the area of breast cancer
Allergy & Immunology - Sublingual immunotherapy effective in mite-induced respiratory allergy
Allergy & Immunology - Sublingual immunotherapy safe in children under 5
Allergy Medicine - New findings in allergy medicine described
Alzheimer Disease - Biotechnology company commences phase I clinical trial of PBT2
Alzheimer Disease - Chemical decoy shows promise for slowing AD by acting as decoy
Alzheimer Disease - HSV amplicon-mediated vaccine reduces amyloid beta deposition in murine brains
Cancer Therapy - Reports advance knowledge in cancer therapy research
Alzheimer Disease - Recent findings in Alzheimer disease described
Angina Therapy - Ranolazine superior to atenolol for treatment of chronic angina pectoris
Anthrax Vaccines - Studies advance knowledge in anthrax vaccines research
Antibiotic Resistance - Staphylococcus aureus studied, prevalence of methicillin-resistance revealed
Antidepressants - TPH and 14-3-3zeta upregulated in fluoxetine-treated cells
Cancer Therapy - Studies add new findings to cancer therapy body of knowledge
Antigen Processing - Membrane localization of transporter linked with antigen processing revealed
Antimicrobials - Findings advance knowledge in antimicrobials research
Antioxidant - Trolox enhances arsenic-mediated oxidative stress and apoptosis in APL
Antipsychotic Therapy - Chronic effects of clozapine on nucleus accumbens dopamine output clarified
Antipsychotic Therapy - Clozapine-induced weight gain linked to 5HT2C receptor -759C/T polymorphism
Antipsychotic Therapy - Effects of chronic risperidone treatment on frontal cortex genes determined
Diabetes Pathogenesis - Researchers' work adds to diabetes pathogenesis body of knowledge
Antisense Technology - Antisense agent AEG 35156 targets the X-linked inhibitor of apoptosis protein
Antisense Technology - VIP-polylysine mediates the uptake of radioiodinated antisense molecules
Apoptosis - Glutaredoxin examined role of overexpression in apoptosis defined
Apoptosis - P21(WAF1) examined, physiological effects in fibroblast revealed
Arrhythmia - HIV protease inhibitors may predispose patients to cardiac arrhythmias
Asthma - New findings may help explain treatment failure
Diabetes Pathogenesis - Studies advance knowledge in diabetes pathogenesis research
Asthma - Pharmaceutical company announces results in phase IIa study on asthma treatment
Atopic Dermatitis - Phase III clinical trial with Primolux for atopic dermatitis, psoriasis begins
Autoimmune Diseases - Rituximab is a promising therapy for refractory autoimmune diseases
Avian Influenza - Asian bird flu vaccine now safe enough to use, but can we make it?
Avian Influenza - Biopharmaceutical company evaluates Alferon LDO as potential avian flu therapy
Awards - Clinical research company wins Clinical Research Team of the Year Award
Diabetes Therapy - New findings in diabetes therapy described
Awards - Life sciences research company awarded U.S. NIH grant to develop screening tool
Awards - Microscopy Society of America 2005 Outstanding Young Scientist announced
Awards - Myeloma foundation announces 3 winners of targeted therapeutics initiative
Bacteriology - College group issues meningococcal disease immunization recommendations
Benign Prostate Hyperplasia - Development of treatment for benign prostate hyperplasia to continue in Japan
Biological Therapies - Enamel matrix derivative inhibited breast cancer cell attachment to bone
Diabetes Therapy - New findings in the area of diabetes therapy described
Biomedical Engineering - Copper-supplemented implants generate vessel growth in healing bone grafts
Biomedical Engineering - Reengineered T cells acquire tumor-specific reactivity
Bioterrorism - Novel GF nerve agent antidotes synthesized
Bipolar Disorder - Biopharma company enters agreement with Stanley Medical Research Institute
Bipolar Disorder - Definition of mania may be too loose
Bipolar Disorder - Research looks beyond lithium to treat psychiatric disease
Diabetes Therapy - Reports describe recent advances in diabetes therapy research
Blood Brain Barrier - Hypoxia/aglycemia studied, role in expression of occludin and actin clarified
Blood Cell Substitute - Liposomes encapsulating hemoglobin evaluated as a red blood cell substitute
Bone Marrow Cancer Diagnostics - Proposal of morphologic bone marrow response score for imatinib treatment in CML
Bone Marrow Cancer Therapy - Production of TGF-beta1 and IFN-gamma linked to regeneration of hematopoiesis
Bone Marrow Transplantation - BMT successful in a patient with c-mpl-mutated CAMT from carrier donor
Brain Tumor - GRP78 expression correlates with favorable prognosis in neuroblastic tumors
Diabetes Therapy - Researchers detail new studies and findings in the area of diabetes therapy
Breast Cancer - Adjuvant treatment for node-positive breast cancer approved in Europe
Breast Cancer - Cardiac death after radiation for breast cancer dramatically down, study shows
Breast Cancer - Findings in breast cancer provide new insights
Breast Cancer - Interleukin-1beta induces IL-8 mRNA stabilization in breast cancer cells
Breast Cancer - Oncolytic herpes simplex virus diminishes mammary tumors in mice
Diabetes Therapy - Studies describe new findings in diabetes therapy research
Business - Company expands portfolio of proteins for drug development
Business & Finance - Alferon maker reports on 2004: Assets, total shareholders equity increased
Business & Finance - Biomaterials company updates U.S. FDA approval status of vein graft treatment
Business & Finance - Biopharmaceutical company announces name change and series C financing
Business & Finance - Biopharmaceutical company receives milestone payment from Yamanouchi
Business & Finance - Biopharmaceutical firm reports loss of $0.10 per share, provides pipeline update
Diabetic Nephropathy - Recent findings illuminate research in diabetic nephropathy
Business & Finance - Biotechnology company announces 2004 year end operational and financial results
Business & Finance - Biotechnology company announces financial results
Business & Finance - Company regains compliance with NASDAQ stockholders' equity listing requirement
Business & Finance - Developer of anti-infective therapies announces reverse stock split
Business & Finance - Developer of humanized monoclonals announces financial results
Business & Finance - MedPulser maker reports on "year of transformation"
Malaria Vaccines - Recent studies add new data to malaria vaccines research
Business & Finance - Pharmaceutical company announces 8% increase in net revenues for fourth quarter
Business & Finance - Pharmaceutical company announces third quarter financial results
Business & Finance - Pharmaceutical company reports unaudited results for 4th quarter, full year 2004
Business & Finance - Pharmaceutical firm announces increase in dividend, new collaboration
Business & Finance - Pharmaceutical firm reports $0.06 per share loss, clinical pipeline update
Business & Finance - Prestara maker reports 2004 revenues of $5.6 million
Oncology - Reports describe recent advances in oncology research
Business & Finance - Ventavis maker reports "remarkable" year
Business Update - Agricultural company and genetics company announce collaborative relationship
Business Update - Allergy drug maker reports change in shareholding
Business Update - Biopharmaceutical company makes interview with CEO available online
Business Update - Bioscience group names board of directors, provides update
Business Update - Biotech company enters supply agreement with Mayo Foundation
Oncology - Researchers provide details of new studies and findings in the area of oncology
Business Update - Biotechnology companies broaden antisense drug development partnership
Business Update - Companies agree to develop, commercialize DURECT'S 7-day transdermal pain patch
Business Update - Company announces completion of 3-year sales agreement for high activity cobalt
Business Update - Company announces expansion of SuperAntibody research and development program
Business Update - Company provides update on European regulatory review of ATryn
Business Update - Company to develop next-generation reservoir-based drug-eluting stents
Oncology - Studies describe new findings in oncology research
Business Update - Developer of drug-eluting coatings reports 2004 year end results
Business Update - Erasmus MC in Rotterdam licenses access to Ingenuity Pathways Analysis software
Business Update - FDA advisory committee recommends Boostrix
Business Update - FDA rejects Public Citizen's petition for Crestor
Business Update - Global Access Program for HIV therapies to include additional countries
Business Update - Medical manufacturing company signs private label agreement
Osteoporosis - Researchers provide details of new studies and findings in the area of osteoporosis
Business Update - Nanotechnology-focused company launches new start-up biotechnology company
Business Update - Oncology-focused pharmaceutical company ends proposed acquisition of Synt:em
Business Update - Pharma company and animal health company form strategic alliance
Business Update - Pharma company announces new structure for research and development
Business Update - Pharma company retains Piper Jaffray & Co. as strategic advisor
Business Update - Pharmaceutical company appoints Peterson & Co., LLP, as new auditors
Virology - Recent studies add new data to virology research
Business Update - Pharmaceutical company reports on approved management proposals
Business Update - Research company announces collaborations with university and medical foundation
Business Update - Web site database now exceeds 11,000 products
Cancer Drugs - Doxorubicin and cisplatin chemotherapy used in spindle cell sarcomas of the bone
Cancer Drugs - Efficacy, safety, and steady-state pharmacokinetics of MS Contin XL reviewed
Cancer Immunotherapy - Inhibitory anti-FLT3 antibodies rebuff leukemic induction
Virology - Reports advance knowledge in virology research
Cancer Prognosis - Increased stromal versican related to higher lung tumor recurrence rate
Cancer Research - Anti-cancer therapy product found to enhance effect of leading cancer drug
Cancer Research - Avastin licensed for use in combination with chemotherapy in England
Cancer Screening - Screen for leukemia resistance identified mutation pattern for PD166326
Cancer Therapy - Arsenic use endorsed in leukemia therapy
Cancer Therapy - Artemisinin-tagged holotransferrin affected cancer cells
Virology - Reports describe recent advances in virology research
Cancer Therapy - Cancer patients with viral hepatitis benefit from hepatic artery chemotherapy
Cancer Therapy - Combinatorial strategies overcome the obstacles of cancer gene therapy
Cancer Therapy - Company reports 67% decrease in metastatic nodules with CTCE-9908
Cancer Therapy - INGN 241 induced programmed cell death in 100% tumors treated in study
Cancer Therapy - Interferon and perindopril combine to fight angiogenesis and cancer growth
Cancer Therapy - Localized radiation treatment directly to site improves cancer treatment
Cancer Therapy - Online pharmacy cosponsors cancer treatment program in Japan
Cancer Therapy - Phase II trial of cancer drug GCAN 101 to start in Israel
Cancer Therapy - Recent studies add new data to cancer therapy research
Cancer Therapy - Revlimid exceeds expectations in relapsed, refractory myeloma
Cancer Therapy - Selective cytotoxicity and telomere damage in leukemia cells by using BIBR1532
Cancer Therapy - The G-quadruplex-interactive molecule BRACO-19 inhibited tumor growth
Cancer Therapy - The TK1-2 domain of tissue-type plasminogen activator shuts down tumor growth
Cancer Therapy - Viral persistence after transfection slows tumor cell growth
Cardiology - Cardiac computed tomography groups merge to form single cardiovascular society
Cardiomyocytes - Results underline importance of selenium dietary intake
Cardiovascular Disease - Phase I trial initiated for oral ISIS 301012 in high cholesterol management
Cardiovascular Research - 5-HT1A receptors are involved in cardiovascular stress responses
Cervical Cancer - Nonsurgical options available to treat HPV-related disease
Chemotaxis - UCB neutrophils yield same potency pattern for each ELR chemokine as adult cells
Chemotherapy - Researchers examine rhIL-11 for use in children with solid tumors or lymphomas
Chemotherapy - Techniques hold promise identifying patients at risk for cardiac toxicity
Chemotherapy - Update on agents utilized for perioperative intraperitoneal chemotherapy
Chlamydia - Studies describe new findings in chlamydia research
Chronic Hepatitis B - Screenings for hepatitis B antigen predict treatment response to lamivudine
Chronic Hepatitis C - Suppressor of cytokine signalling-1 may host interferon resistance
Chronic Liver Disease - Interferon limits fibrosis progression in chronic hepatitis B patients
Chronic Myelocytic Leukemia - Company obtains orphan drug designation for c-Myb Antisense (LR3001) in CML
Clinical Trials - Cardiovascular devices maker initiates enrollment in phase 2 pivotal trial
Clinical Trials - Clinical Trials Solution Suite announced with Microsoft Digital Pharma launch
Clinical Trials - Clinical trials last 30-42% longer due to patient recruitment difficulties
Clinical Trials - Pharmaceutical company unlikely to receive accelerated approval for lupus drug
Clinical Trials - Second SARM shows phase I clinical safety
Coagulation Therapy - Barriers to patient self-testing of prothrombin time in U.S. identified
Coagulation Therapy - Low-dose alcohol may augment antithrombotic effects of warfarin
Colitis Risk Factors - Leflunomide-induced diarrhea and weight loss linked to colitis
Collaborations - Alliance set up for development of nanoparticle composites for drug delivery
Collaborations - Alliance signed with NCI for development of ADH-1 Exherin
Collaborations - Antibody technology licensing agreement extended
Collaborations - Armored RNA technology licensing agreement signed with Ambion
Collaborations - Biotech company appoints master distributor
Collaborations - CF drug-discovery collaboration announced
Collaborations - CFFT inks collaboration to discover RNAi therapeutic to treat cystic fibrosis
Collaborations - Cancer drug developer, Raylo sign manufacturing deal for AS1411
Collaborations - Diagnostics company renews cancer research collaboration with Johns Hopkins
Collaborations - Distribution rights for Tostrex granted to PT Kalbe Farma for the Far East
Collaborations - Enanta Pharmaceuticals achieves milestone in collaboration
Collaborations - Pharmacy benefit manager and Public Health school to develop institute
Collagens - Wound healing studied, variable impairment in collagenase-resistant mouse shown
Complementary & Alternative Medicine - Honeybee products may help control tumor growth
Complementary & Alternative Medicine - Mai-Men-Dong-Tang appears to be a credible treatment for allergic asthma
Complex Regional Pain Syndrome - Sphenopalatine block attenuates CRPS pain
Congestive Heart Failure - Dual vasopressin V1A and V2 receptor antagonists provide greater benefit
Coronary Artery Disease - Positive 12-month results from PISCES trial reported
Creutzfeldt-Jakob Disease - FDA committee meeting focused on transmissible spongiform encephalopathies
Crimean-Congo Hemorrhagic Fever - M RNA of Balkan Crimean-Congo hemorrhagic fever virus strain characterized
Critical Care Medicine - Colistin effective for multiresistant Gram-negative ICU infections
Cystic Fibrosis - Gene-focused company announces trial results for cystic fibrosis treatment
Cystic Fibrosis - Steroid therapy may raise risk of infection with nontuberculous mycobacteria
DNA Vaccines - New findings in the area of DNA vaccines described
Dental Research - Therapeutics company develops new candy to counteract tooth decay
Depression - Pharma company launches depression awareness campaign
Depression Therapy - Self-reports of depressive symptoms accurate in nonpsychotic outpatients
Dermatology - Maker of eczema cream comments on U.S. FDA statement regarding cancer risks
Dermatology - Transcutaneous toluene penetration characterized in rats
Dermatology - Weill Cornell Medical College and cosmetics company announce collaboration
Diabetes - Education program to promote awareness of diabetic peripheral neuropathy
Diabetes Control - Tannic acid shows promise as an antidiabetic drug
Diabetes Pathogenesis - Researchers provide details of new studies and findings in the area of diabetes pathogenesis
Diabetes Research - CS-917 interaction study halted after two serious adverse events
Diabetes Therapy - Beta-cells that secrete GLP-1 have improved glucose-responsiveness
Diabetes Therapy - Findings in diabetes therapy provide new insights
Diabetic Nephropathy - Assessment agreement with U.S. FDA for diabetic nephropathy trials finalized
Diabetic Nephropathy - New data illuminates research in diabetic nephropathy
Diagnostic Imaging - Image probing provides precise quantification of angiogenesis
Diagnostic Imaging - Positron emission tomography monitors tumors treated with suicide gene therapy
Diagnostics - CellTracks Analyzer II gets FDA 510(k) clearance for in vitro diagnostic use
Diagnostics - Protein-DNA chimeras detect and quantify small numbers of molecules
Diagnostics - UPAR may identify breast cancer patients with a risk for micrometastasis
Diagnostics - Urine albumin test offered for complications from heart, kidney disease
Diet & Nutrition - Company launches nutrition line for Latinos
Diet & Nutrition - FTC dismisses vitamin trade group complaint against nutrition products evaluator
Diet & Nutrition - National organizations launch panel discussion series
Diet & Nutrition - Nutrient-dense fruit juice with antioxidants introduced
Diet & Nutrition - OptiNate, prenatal vitamin with vegetarian-sourced omega-3 fatty acids, launched
Disease Associations - S. aureus cidABC and lrgAB operons studied, expression clarified
Disease Associations - Amyloid-mediated neuronal cell death studied, role of polymerization revealed
Disease Associations - Brain natriuretic peptide examined, changes in myocardial necrosis revealed
Disease Associations - EPEC and EHEC adhesion and motility studied, protein dynamics revealed
Disease Associations - Gingipain-containing virulence complex studied, role in immune evasion shown
Disease Associations - Staphylococcal arthritis studied, role of fibronectin-binding factors shown
Drug Delivery - Alginate-NOCC hydrogels show promise for oral protein drug delivery
Drug Delivery - CCA-based liposomes lead gene therapy to cancer cells
Drug Delivery - Drug release from gentamicin-loaded discs characterized
Drug Delivery - EHDA produces nearly monodispersed drug release particles
Drug Delivery - Effects of size and temperature on PLGA degradation characterized
Drug Delivery - FDA approves XOPENEX HFA metered-dose inhaler
Drug Delivery - Factors influencing drug release from bioerodible polymers identified
Drug Delivery - GelVac phase I clinical trial initiated
Drug Delivery - Infusion system receives U.S. FDA 510k clearance
Drug Delivery - Peptide dendrimers offer versatile nucleic acid delivery
Drug Delivery - Positive pharmacokinetic study results reported for ondansetron lingual spray
Drug Delivery - Research add new data to drug delivery body of knowledge
Drug Delivery - Researchers look to microencapsulated 5-fluorouracil for drug administration
Drug Delivery - Selective alkylation improves control of drug release from lipidic cubic phase
Drug Delivery - Therapies differ in their release from hydrogels and microspheres
Drug Delivery - Viruses could deliver HIV, malaria, rabies and cancer vaccines as pills
Drug Development - Antioxidants prevent the desulfurization of antisense oligonucleotides
Drug Development - Biopharmaceutical industry research & development tops $49B in 2004
Drug Development - Cetrorelix development continues with endometriosis as primary indication
Drug Development - Computational-directed research agreement on protein kinases announced
Drug Development - FDA panel recommends approval of Baraclude for hepatitis B
Drug Development - IND filed for gel to treat overactive bladder syndrome
Drug Development - MAO-B inhibitors/iron chelators have promising neuroprotective effects
Drug Development - Milestone reached in antibody-drug conjugate agreement with Genentech
Drug Development - Novel naltrexone prodrugs show promise for transdermal delivery
Drug Development - Phase I trial of oral BCX-4208 for psoriasis completed
Drug Development - Phase II study of Psoraxine for psoriasis does not meet primary endpoint
Drug Development - Phase III trial of iclaprim set to begin for skin infections indication
Drug Development - Positive data reported for Miraxion in treatment of unresponsive depression
Drug Development - Rat model facilitates screening for drugs which reduce L-DOPA dyskinesia
Drug Development - U.S. FDA grants approval of Symlin to treat diabetes patients
Drug Development - UK authorities grant approval for trial of ulcerative colitis therapy
Drug Importation - Pharmacists react to CanaRx exploring importation of drugs from India
Drug Resistance - Chemokine patterns in meningococcal disease investigated
Drug Resistance - Patient with drug-resistant form of HIV identified
Drug Safety - Reasearchers call for revised automated drug alert system
Dry Eye Syndrome - Pharmaceutical company files IND for phase IIb trial of ecabet sodium
Duchenne Muscular Dystrophy - Perindopril treatment delays Duchenne muscular dystrophy heart failure
Eczema - FDA published advisory regarding Protopic and Elidel
Embryonic Stem Cell Research - ESCs differentiate and myelinate after spinal cord transplantation
Embryonic Stem Cell Research - ESCs form organized/functional cardiac conduction system in vitro
Embryonic Stem Cell Research - FGF2 maintains ESC self-renewal by supporting extracellular matrix expression
Embryonic Stem Cell Research - Two-step culture system commits ESCs to epidural cell fate and differentiation
Endocrinology - Antisense neuropeptide Y cRNA lessens weight gain and food intake in animals
Endocrinology - Glucose transporter examined, distribution and role in injury recovery shown
Endocrinology - Marijuana extracts have endocrine-disrupting effects in rats
Endocrinology - VEGF Trap creates reversible ovarian function inhibition in macaques
Endodontics - Calcium hydroxide does not eradicate microbiota causing pulp necrosis
Epidemiology - Gastroenteritis outbreak associated with group A rotavirus/genogroup 1 sapovirus
Epidemiology - Quick action against re-emerging infectious diseases can avert outbreaks
Epilepsy - Zonegran marketing authorization granted by European Commission
Epilepsy Therapy - Dosing algorithm facilitates conversion from valproate to lamotrigine therapy
Epileptic Seizures - Pharmaceutical company launches 100, 300, 400 mg gabapentin capsules
Erythropoietin - Erythropoietin expression analyzed, role of neuronal PAS domain protein shown
Esophageal Cancer - HPTTG overexpression regulated by betacatenin/TCF pathway in esophageal cancer
Esophageal Cancer - p53 negative expression/p53R2 expression predicts CRT outcome in ESCC
Ethics - Is it ethical to use a placebo in clinical trials?
Eye Cancer Therapy - Bendamustine chemotherapy as second-line treatment in metastatic uveal melanoma
Finance - Analyst initiates coverage of nanotechnology firm with a buy rating
Finance - Argatroban developer announces closing of $130M convertible senior note offering
Finance - Biopharmaceutical company announces fourth quarter and fiscal 2004 results
Finance - Biopharmaceutical company reports 2004 year-end financial results
Finance - Biopharmaceutical company reports fourth quarter, 2004 financial results
Finance - Biopharmaceutical company reports fourth quarter, annual financial results
Finance - Biopharmaceutical company reports fourth quarter, year end financial results
Finance - Biotech company files extension for Form 10-K, adjusts 2004 results
Finance - Biotech company reports revenues decreased 41% in 2004
Finance - Biotechnology company reports increase in fourth quarter revenue
Finance - Biotechnology company reports record revenue in 2004
Finance - Cancer therapeutics development company announces financial results
Finance - Cancer-focused pharmaceutical company reports 2004 financial results
Finance - Cancer-focused pharmaceutical company reports 2004 year end, Q4 results
Finance - Cardiovascular drug company raises $17.2M in IPO
Finance - Diagnostics company completes $2.5M financing
Finance - Drug delivery firm notes 39% increase in revenues
Finance - European pharma distrib. co. announces financial results, optimistic about '05
Finance - Functional Somatic Syndrome-focused company reports net loss of about $11.2M
Finance - Healthcare transaction processing services company announces financial results
Finance - Humanized antibodies developer announces improved financial results
Finance - Immunotherapeutics maker reports 2004 revenue of $25.0M; down from 2003
Finance - Immunotherapy company reports 2004 net loss of $54.2 million
Finance - Lab services provider announces financial deal
Finance - Maker of carbohydrate-based drugs closes on first tranche of $6.5M financing
Finance - Monitoring systems company reports loss for second quarter
Finance - Multiple sclerosis drug developer reports loss of $0.01 per share
Finance - Nanotechnology company updates shareholders on recent developments
Finance - Nutritional supplements company reports 1.6% decrease in 2004 net sales
Finance - On-demand workspaces provider announces 12th consecutive quarter of growth
Finance - Oncology company reports fourth quarter and year end financial results
Finance - Pharma company announces financial results with tripled profit after tax gains
Finance - Pharmaceutical company receives Skoll Award for Social Entrepreneurship
Finance - Pharmaceutical company reports fourth quarter and year-end results
Finance - Pharmaceutical company reports loss of $0.88 per share for second quarter
Finance - Pharmaceutical company reports second fiscal quarter and 6-month results
Finance - Pharmaceutical company sets deferred valuation allowance, adjusts GAAP results
Finance - Pharmaceutical firm expects considerable growth in sales, earnings in 2005
Finance - Pharmaceutical firm reports 8% increase in sales
Finance - Pharmaceutical firm reports loss of $0.23 per share
Finance - Pharmaceutical firm reports net loss of $0.41 per share
Finance - Pharmaceutical firm to restate 2001-2003 financial statements
Finance - Proquin maker reports a net loss of $26.9 million in 2004
Finance - Provenge maker reports year-end revenues of $5 million
Finance - Provider of healthcare products to China announces $6.5M private placement
Finance - U.S. government funds cancer program to train investigators
Flatfoot - New clinical practice guideline published to treat flat feet in adults
Foot & Mouth Disease - Key target revealed for potential drug against devasating livestock disease
Gastric Cancer - COX-2 correlates with F-box protein/Skp2 expression/prognosis in gastric cancer
Gastric Cancer - Case of gastric tumor of the Carney triad reported
Gastroenterology - Metastatic lesions flare following primary colorectal cancer removal
Gastroenterology - Montmorillonite protects plasmid DNA from the gastrointestinal environment
Gastroenterology - Researchers publish new studies and findings in the area of gastroenterology
Gastroenterology - Thymidine phosphorylase has differential effects in the tumor microenvironment
Gene Activation - Tumor cell HLA-G gene activation involves cis-acting epigenetic changes
Gene Research - Adipose differentiation-related protein shows clear-cell renal cancer status
Gene Research - Corautus announces contract in connection with GENASIS gene therapy trial
Gene Research - GENE impedance regulates gene expression via generalized mechanisms
Gene Silencing - Overexpressed exportin 5 augments RNA interference
Gene Transfer - The decorin transgene stops breast cancer metastasis
Generic Drugs - Blockbuster drugs with expiring patents gain new hope
Generic Drugs - Pharma company enters agreement with STADA Pharmaceuticals
Genetic Research - Hematopoietic cells carrying the ribonuclease inhibitor gene hinder melanoma
Genetics & Genomics - ChIP-GLAS launched for simultaneous detection of 20,000 human promoters
Genetics & Genomics - Study analyzes X chromosome
Genetics & Genomics - The Sentrix Human-6 BeadChip, Sentrix HumanRef-8 BeadChip now available
Genetics & Genomics - Validation study completed for in situ hybridization technique
Genetics and Genomics - Advanced Gene Expression Service provider program launched
Glioma - U.S. FDA approves use under IND of monoclonal antibody in child with glioma
Glycemic Control - Reports add new data to glycemic control research
Gossypol - (-)-Gossypol overcomes Bcl-2-mediated and Bcl-X-L-mediated apoptosis resistance
Graft-Versus-Host Disease - Antilymphocyte/thymocyte globulins reduce acute/chronic GvHD incidence/severity
Grants - Company announces award of SBIR phase 1 grant for program in neurobiology
Gynecology - Matrilysin uses progelatinase to generate ovarian cancer cell invasion
HIV-2 Drug Mutation - Polymorphisms specific to HIV-2 identified in untreated patients
HIV/AIDS - Enrollment initiated in phase I/II study for new HIV entry inhibitor
HIV/AIDS Biotechnology - EIA quantifies plasma and intracellular lopinavir in HIV-infected patients
HIV/AIDS Drug Action - Pharmacodynamics of CYP3A inactivation by HIV protease inhibitors determined
HIV/AIDS Drug Development - Interlocked dimeric parallel-stranded DNA quadruplex inhibits HIV-1 integrase
HIV/AIDS Drug Development - Recombinant cyanovirin-N developed for use as vaginal anti-HIV microbicide
HIV/AIDS Drug Development - Tuftsin-AZT inhibits HIV RT and augments host immunogenic cell function
HIV/AIDS Drug Interaction - Pharmacodynamics/pharmacokinetics help manage HIV-1 protease inhibitors
HIV/AIDS Drug Mechanism - Efavirenz enhances HIV-1 RT p66/p66 and p51/p51 homodimer interactions
HIV/AIDS Drug Therapy - Cellular mechanisms described for protease inhibitor-induced metabolic syndrome
HIV/AIDS Epidemiology - Low CCR5Delta32 frequency related to higher susceptibility to HIV-1 infection
HIV/AIDS Immune Activation - Use of HAART and other factors increase oxidative damage
HIV/AIDS Lipodystrophy - Metabolic and body composition changes vary according to HAART choice
HIV/AIDS Pathogenesis - CD8+ cells from HIV-1-infected patients lack functional recall memory to HIV gag
HIV/AIDS Pathogenesis - HIV-1 RRE heterogeneity important in viral pathogenesis and disease progression
HIV/AIDS Pathogenesis - HIV-1 Vpr inhibits maturation and activation of macrophages and dendritic cells
HIV/AIDS Pathogenesis - Modeling approach shows impact of HIV mutations on immune system
HIV/AIDS Prevention - Discrete-event simulation evaluates vertical transmission prevention strategies
HIV/AIDS Research - APOBEC3-edited HIV G->A hypermutants recovered by PCR method
HIV/AIDS Research - Advances in laboratory testing for HIV used to follow disease process
HIV/AIDS Research - Expression system provides hydrophobic peptide from HIV-1 p24 protein
HIV/AIDS Research - Patient enrollment for South African phase 3 trial HIV-1 treatment complete
HIV/AIDS Research - Redox status of cells regulated through complex and tightly regulated mechanism
HIV/AIDS Therapy - Completed phase II study with MIV-310 does not justify further development
HIV/AIDS Therapy - DNC not important in mtDNA depletion of anti-HIV dideoxynucleosides
HIV/AIDS Therapy - Protease inhibitor choice should maximize efficacy and patient tolerability
HIV/AIDS Therapy - Research add new data to HIV/AIDS therapy body of knowledge
HIV/AIDS Treatment - Phase 2 trial of analgesic for HIV-associated neuropathic pain terminated
HIV/AIDS Vaccines - Reports describe recent advances in HIV/AIDS vaccines research
HIV/AIDS-Related Cardiology - Metabolic changes occurring with HAART increase heart disease risk
HIV/AIDS-Related Diabetes - Apparent type 1 diabetes resolves in AIDS patient with CMV coinfection
HIV/AIDS-Related Disorder - TTP is responsive to plasma infusion therapy in HIV/AIDS
HIV/AIDS-Related Lipodystrophy - Buffalo hump in HIV-associated lipodystrophy associated with hyperinsulinemia
HIV/AIDS-Related Orthopedics - Sepsis not seen during 1-year follow-up of orthopedic implants in HIV infection
HIV/AIDS-Related Pneumonia - SIV-associated pneumonia correlates with increased chemokine/RNA in lungs
HIV/AIDS-Related Tumor - Cardiac tumor was initial manifestation of AIDS
Head & Neck Cancer - Supracricoid hemilaryngopharyngectomy in patients with squamous cell carcinoma
Head and Neck Cancer - CD105 microvessel density marks the prognosis of squamous cell carcinoma
Head and Neck Cancer - Endostatin diminishes angiogenic activity in squamous cell carcinoma
Head and Neck Cancer - Findings describe new data in head and neck cancer research
Healthcare Coverage - California prescription medicine service launched
Healthcare Coverage - National survey shows causes for delay by lesbians in obtaining health care
Heart Disease Therapy - Key enzyme is secreted by heart mast cells
Heart Failure - Cardiac resynchronization therapy saves lives, reduces hospitalizations
Hematology - Adeno-associated virus-mediated gene transfer fuels erythropoietin production
Hematology - Overexpressed HOXB6 gene is implicated in acute myeloid leukemia
Hematology - Recent findings in hematology described
Hematology - Retinoic acid steroidal analogs may cure human leukemia
Hepatic Injury - Acute hepatic injury studied, tributylmethyl ammonium excretion clarified
Hepatitis B Prevention - Hepatitis B vaccine does not stop viral recurrence after liver transplantation
Hepatitis B Therapy - Hepatitis B virus polymerase gene mutations reduce clinical outcomes
Hepatitis B Therapy - Interferon triggers anti-inflammatory activity in chronic hepatitis B patients
Hepatitis B Virus Therapy - Antiviral pressure is low among those infected with hepatitis B in Vietnam
Hepatitis C Therapy - Early treatment of acute hepatitis C benefits patients coinfected with HIV
Hepatitis C Therapy - Nucleotide inhibitors staunch hepatitis C virus replicase
Hepatitis C Therapy - Viramidine achieves steady state levels in patients with hepatitis C
Hepatology - Cytoprotective TNF-alpha-inducible proteins identified in mouse liver
Hepatology - Stress-activated MAPKs mediate rubratoxin B-induced hepatotoxicity
Hereditary Angioedema - Phase 3 clinical trial for treatment of hereditary angioedema initiated
Hereditary Angioedema - Recombinant human C1 inhibitor results for hereditary angioedema presented
Hormones - Hormone levels in relation to body composition studied, patterns revealed
Imaging - Technology company announces consulting agreement, acquisition of patent
Immunology - Batracyclin derived muramyl dipeptides studied, biological activity reported
Immunology - Reports describe recent advances in immunology research
Immunomodulation - Aloe polysaccharides studied, role of size in immunomodulation identified
Implantable Cardiac Defibrillators - ICDs lead to reductions in mortality in patients with CAD and a ventricular scar
Inflammation - Histamine H1 receptor antagonist studied, effect on cytokine production revealed
Influenza Vaccine - Chinese government grants new drug certificate for split flu vaccine
Information Technology - Application developer supports Microsoft's Digital Pharma initiative
Information Technology - Business intelligence provider announces support for digital pharma initiative
Information Technology - ChemTree drug-discovery software for Mac OS X released
Information Technology - Collaborative effort focused on developing portal for U.K.'s MHRA
Information Technology - Hospital implements infusion system technology for intravenous medication
Information Technology - Information Technology company announces digital pharma initiative
Information Technology - Information technology co. provides electronic data capture for clinical trial
Information Technology - Life science consulting firm announces latest release of communication solution
Information Technology - Memorandums signed by standards groups for prescription drug programs
Information Technology - Pharmaceutical firm provided with global electronic patient diary technology
Information Technology - Technology company announces support for Microsoft Digital Pharma
Intestinal Tuberculosis - Imaging findings described for intestinal tuberculosis
Joint Replacement - Novel bisphosphonate may reduce particle-induced osteolysis with one dose
Kaposi Sarcoma-Associated Herpesvirus - New findings in the area of kaposi sarcoma-associated herpesvirus detailed
Klebsiella Pneumoniae - ESBL-positive K. pneunmoniae clones cause sustained epidemic outbreaks
Knee Replacement - Utility of Simplex and Palacos bone cements in antibiotic spacers compared
Langerhans Cell Histiocytosis - Cladribine may be effective for patients with CNS disease
Legal Issues - Denial of motion to prevent launch of generic forms of dental drug recommended
Leukapheresis - SC mobilization influences CD34+ cell collection efficiency of leukapheresis
Leukemia - Treatment and survival of adults with acute leukemia in the Primorsky Region
Liver Cancer - Aberrant Pim-3 expression encourages hepatocellular carcinoma proliferation
Liver Cancer - Gefitinib prevents hepatocellular carcinoma development in cirrhotic liver
Liver Cancer - Molecular mechanisms of Fenretinide clarified
Lung Cancer - Clinical pathway plotted by evidence-based medicine for lung cancer chemotherapy
Lung Cancer - Data published on nanoparticle delivery of mda-7 in lung cancer
Lung Cancer - Patient enrollment complete in trial of Xcytrin for lung cancer brain metastases
Lymphoma - CVP chemotherapy combined with rituximab improves patients' outcomes
Malaria Vaccines - New data illuminates research in malaria vaccines
Marketing - Drug companies spend over $50M on prelaunch marketing of blockbuster drugs
Mastocytosis - Open-label study of ZYFLO begins
Matrix Metalloproteinase - Matrix metalloproteinases studied, roles in cardiac allograft rejection revealed
Medical Devices - Long-term benefit of drug delivery device after breast cancer surgery shown
Medical Errors - Survey shows many second medical opinions result in different treatments
Melanogenesis - Glycyrrhizin induces melanogenesis by cAMP elevation in melanoma cells
Melanoma - Imiquimod shows promise for topical treatment of lentigo maligna
Melanoma - PUMA expression may be prognostic marker for human melanoma
Melanoma Therapy - Mofarotene inhibited melanoma cell motility
Memory - Cortistatin investigated, modulation of memory evocation revealed
Meningococcal Vaccine - Company seeks U.S. FDA approval to broaden age group for meningococcal vaccine
Menopause - NIH panel calls for "demedicalization" of menopause
Mental Health - Neurotrophic factor analyzed, involvement in macrophage activation revealed
Mergers & Acquisitions - Biopharma company acquires assets of Savetherapeutics A.G.
Mergers & Acquisitions - Biotechnology company closes merger with Panacos Pharmaceuticals
Mergers & Acquisitions - Companies join to form drug-eluting coronary stent company
Mergers & Acquisitions - Epimmune and immunotherapy company to combine businesses
Mergers & Acquisitions - Intellectual property of German biotech Savetherapeutics AG acquired
Mergers & Acquisitions - Pharmaceutical firms reorganize post-merger
Metabolic Syndrome - Researchers' work adds to metabolic syndrome body of knowledge
Micelles - Reverse micellar systems examined, protein back-extraction processes clarified
Multiple Myeloma - PML mediates IFN-alpha-induced myeloma apoptosis by regulating TRAIL induction
Multiple Sclerosis - Biotech company announces genes involved in multiple sclerosis identified
Multiple Sclerosis - Withdrawal of multiple sclerosis drug target brings questions about others
Mutagenesis - Hepatitis C type 1b E2-PePHD mutations are not linked to treatment response
Myeloma - Heparanase promotes spontaneous metastasis of myeloma cells to bone
Myocardial Infarction - Culprit lesion calcium is independent predictor of poor outcome
Myocardial Infarction - Findings describe new data in myocardial infarction research
Nail Fungus - Drug delivery company updates phase 1 clinical trial of nail fungus treatment
Nanotechnology - Genomics company continues to develop Nano-JETA Platform
Nanotechnology - Newest additions to nanotechnology consortium announced
Nasopharyngeal Cancer - U.S. FDA grants 510(k) clearance for applicator for brachytherapy treatments
Neural Stem Cell Research - Adhesion molecule L1 stimulates neuronal migration through Vav2-Pak1 signaling
Neural Stem Cell Research - Astroglial cells support maturing neuron migration and neurite elongation
Neural Stem Cell Research - Neural regeneration in chick retina useful model system for retinal regeneration
Neural Stem Cell Research - Nrf2 stabilization by tBHQ protects against oxidative stress-induced NSC death
Neural Stem Cell Research - Rotenone and camptothecin induce caspase 9/3-dependent apoptosis in NSCs
Neuroblastoma - Human neuroblastoma cell growth inhibited by CAY10404
Neurology - Amylold beta peptide studied, effects of induced Ca2+ signals defined
Neurology - New findings in the area of neurology detailed
Neuroscience - Caspase-3 causes brain capillary endothelial and cancer cells to self-destruct
Non-Small Cell Lung Cancer - Avastin plus chemotherapy extends survival in first-line non-squamous NSCLC
Obesity and Diabetes - Data advance knowledge in obesity and diabetes research
Obsessive-Compulsive Disorder - Drugs alone are not enough for fighting obsessions and compulsions
Obstetrics - Active management of third stage of labor greatly reduces postpartum hemorrhage
Obstetrics - Prophylactic use of progesterone in preterm labor needs more study
Obstetrics - Use of antibiotics to prevent premature birth debated
Occupational Health - Workers chronically exposed to trichloroethylene need periodic screenings
Oncology - DNA-PK inhibition is a viable strategy for enhancing ionizing radiation
Oncology - Drugs that challenge Ero1-L alpha may beat hypoxia-generated tumor growth
Oncology - Drugs that regulate VEGF augment therapies that treat hematologic cancers
Oncology - Gene-loaded dendritic cells kindle a response to breast cancer antigens
Oncology - Genes predispose breast cancer patients to tamoxifen-induced fatty liver
Oncology - Melanoma differentiation-associated-7 gene transfer eradicates prostate cancer
Oncology - Methionine aminopeptidase 2 inhibitors cut off cancer growth in mice
Oncology - Oncolytic virus and radiotherapy join to treat squamous cell carcinoma
Oncology - Reports advance knowledge in oncology research
Oncology - Ron receptor signals influence mammary tumor development and metastasis
Oncology - STAT3 decoy erases tumor growth in xenograft models
Oncology - VEGF is a strong prognostic indicator for breast cancer
Oncology - VEGF-A and VEGFR-2 correlate with tamoxifen response in breast cancer patients
Oral Health - Genetic shifts in injured oral mucosa define potential therapeutic targets
Osteomyelitis - Antibiotic-loaded PAA-gelatin hydrogels show promise
Osteoporosis - New findings in the area of osteoporosis described
Osteoporosis Therapy - Taurine protects against alendronate-induced gastric damage in rats
Ovarian Cancer - Clinical trial of monoclonal antibody seeks patients with advanced disease
Overactive Bladder - Pharmaceutical companies initiate phase IV study of overactive bladder treatment
Pain Management - Acetaminophen, when taken as directed, is safe for patients with liver disease
Pain Management - Article describes gene therapy strategy for inflammation-associated chronic pain
Pain Management - Company gives Quadramet clinical development and commercialization update
Pain Medicine - Daily repeated magnetic field shielding induces analgesia in CD-1 mice
Pancreatic Cancer - Increased expression of betaTRCP1 associated with chemoresistance
Pancreatic Cancer - New therapies needed for treating ductal pancreatic adenocarcinoma
Pancreatic Cancer - Raltitrexed and gemcitabine not recommended for patients with pancreatic cancer
Papillomavirus Infection - Human papillomavirus identified in oral cavity tumors
Parkinson Disease - Continuous L-DOPA delivery reverses dyskinesia in an animal model
Patents - Company issued patent for human factor 5A genes, 2 others for agricultural use
Patents - Software company receives patent on mobile health care applications
Patents - Technologies company granted European patent in chronic heart failure
Patents - Test to predict genetic predisposition to poor metabolism of drugs wins patent
Patents - U.S. patent issued for treatment of AIDS
Patents - U.S. patent issued for use of compound to treat uterine fibroids, endometriosis
Pediatric Neurology - Power Doppler images assess neovascularization in childhood moyamoya syndrome
Percutaneous Coronary Intervention - European cardiologists: Bivalirudin should replace heparins in PCI
Percutaneous Intervention - Balloon-catheter thrombin delivery can resolve massive retroperitoneal bleeding
Periodontitis - Periodontitis studied, role of proteinase-activated receptor-2 agonist revealed
Personnel - Biology-based company appoints CFO and VP research to management team
Personnel - Biopharmaceutical company announces appointment of new board member
Personnel - Biopharmaceutical company announces new board of directors appointment
Personnel - Biopharmaceutical firm appoints David J. O'Reilly as president
Personnel - Biopharmaceutical firm appoints new VP of clinical development
Personnel - Biotech company adds hematology researcher to scientific advisory board
Personnel - Biotech company announces management changes
Personnel - Biotech company appoints new board members
Personnel - Carl Siekmann joins German biopharmaceutical company
Personnel - Chemical genetics company appoints Peter Fuller chief business officer
Personnel - Developer of respiratory disease therapies names 2 to direct product development
Personnel - Developer of stem cell expansion products announces new president and CEO
Personnel - Drug development company appoints commercial director
Personnel - Gary Lessing and Michael Atkin named to biopharmaceutical company's board
Personnel - Gerry Braun appointed chief financial officer by drug diagnostics company
Personnel - Healthcare consulting company adds to scientific advisory team
Personnel - Healthcare products company nominates member to board
Personnel - Hooper, Linsley and Fletcher named to board of viral disease-focused company
Personnel - Japanese biopharmaceutical company names David Chiswell non-executive chairman
Personnel - Lifesciences organization names senior director, equipment validation services
Personnel - Michael Wood, MD, and Martin Rosenberg, PhD, named to board of Cubicin maker
Personnel - Muscular dystrophy expert joins scientific advisory board
Personnel - Neurology/psychiatry-focused pharma names Thomas N. Chase, MD, as CEO
Personnel - Pharma company announces management promotions
Personnel - Pharma company names executive vice president of commercial development
Personnel - Pharmaceutical company announces departure of president and cofounder
Personnel - Pharmaceutical company announces management change
Personnel - Pharmaceutical firm appoints new VP, regulatory affairs, quality assurance
Personnel - Pharmaceutical firm board member resigns
Personnel - Pharmaceutical firm continues to build management team
Personnel - Philip Needleman, August Watanabe named to drug company's board of directors
Personnel - Rudi E. Moerck hired as consultant by cancer-focused pharmaceuticals company
Pertussis Vaccines - Researchers describe findings in pertussis vaccines studies
Pharmaceutical Research - Eighty percent of pharmaceutical publications spending outsourced in 2004
Pharmaceutical Research - Pharmaceutical co-promotions depend on overcoming differences
Pharmaceutical Research - Research shows marketing investment for drug launch not reciprocal to team size
Pharmaceutical Research - The pharmacokinetics of nelfinavir change in HCV and HIV coinfected patients
Pharmaceuticals - Cysteine and hydrogen peroxide reaction kinetics and mechanism clarified
Pharmacology - Mixed-effects propensity adjustment improves accuracy of observational studies
Physiology - Stratum corneum studied, proteinase effects of glycolic acid revealed
Pneumococci - Positive data reported from Group-Common Pneumococcal Vaccine clinical studies
Post-Irradiation Sarcoma - Rare case of post-irradiation sarcoma after external beam radiation therapy
Preeclampsia - Study supports use of aspirin in treating pregnancy disorder
Premature Delivery - Phase I clinical trial with MN-221 to prevent preterm labor
Primary Sclerosing Cholangitis - Mycophenolate mofetil marginally effective as PSC therapy
Product Licensing - Company licenses rights to EntreMed for tubulin inhibitor program
Product Licensing - Pharmaceuticals company licenses novel lipid-lowering drug
Product Licensing - Technology licensed from Galmed for treatment of fatty liver disease
Prostate Cancer - Device company announces data in study of prostate cancer treatment
Prostate Cancer - Dietary lycopene and other carotenoids may protect against prostate cancer
Prostate Cancer - Dipeptidyl peptidase defeats the malignant phenotype of prostate cancer cells
Prostate Cancer - Doctor completes 50th treatment with minimally invasive prostate cancer therapy
Prostate Cancer - U.S. CMS issues coverage determination for Abarelix
Prostate Cancer - uPA mRNA and uPAR mRNA expression seen in adenocarcinomas & benign hyperplasias
Prostate Cancer Risk - Positive association for higher birth length/weight & metastatic prostate cancer
Prostate Cancer Therapy - Androgen deprivation therapy influenced metabolism of prostate cancer patients
Prostate Cancer Therapy - Treatment options in hormone-refractory metastatic prostate carcinoma reviewed
Proteomics - Angiogenin promotes cancer cell proliferation as well as angiogenesis
Proteomics - Angiopoietins are direct activators of endothelial cells and neutrophils
Proteomics - Fibroblast growth factor 2 upregulates p12 in endothelial cells
Proteomics - Hela-type caldesmon delineates tumor endothelial cells
Proteomics - Studies describe new findings in proteomics research
Pulmonary Medicine - Research in pulmonary medicine provides new insights
Quantitative Determination - Method used square wave voltammetry for quantitative determination
Radiation Therapy - Curcumin improves skin wound healing in irradiated mice
Radical Prostatectomy - Alpha-blocker therapy and cystography not needed for early catheter removal
Radiotherapy Side Effects - Phase III pilot study of dose escalation using radiotherapy in prostate cancer
Reproductive Health - Drug regulating agency rules Yasmin may be taken by competing female athletes
Respiratory Medicine - (S)-albuterol may compromise the efficacy of (R)-albuterol in asthma patients
Respiratory Syncytial Virus - In vivo efficacy data presented from Alnylam RSV program at AAAAI meeting
Retinopathy - Photoreceptor degeneration accompanies choroidal neovascularization
SARS - Researchers provide details of new studies and findings in the area of SARS
SARS Coronavirus - New data illuminates research in SARS coronavirus
SIV Pathogenesis - Peripheral destructive processes main cause of T cell depletion in SrV infection
Salmonella Infection - Salmonella variation responsible for differences within herd dynamics
Schistosomiasis - Reports add new data to schistosomiasis research
Sepsis - Cefpirome is suitable for treatment of soft tissue infections in septic patients
Sepsis Therapy - Time-to-positivity assay can improve antibiotic management of septic patients
Smallpox - Smallpox drug in preclinical development to study primate efficacy, human safety
Smallpox - Vaccinia Immune Globulin contract awarded by Canadian government
Smallpox Vaccines - Researchers describe findings in smallpox vaccines studies
Stem Cell Research - Companies announce collaboration on diabetes-focused stem cell studies
Stem Cell Research - Epidermal stem cells are dispersed along the basal compartment
Stem Cell Research - FLICE/caspase-8 triggers anoikis induced by beta(1)-integrin blockade in KSC
Stem Cell Research - Hair graying caused by defective self-maintenance of melanocyte stem cells
Stem Cell Research - IFN-gamma negatively modulates self-renewal of repopulating HSCs
Stem Cell Research - Low-dose total body irradiation causes clonal fluctuation of stem cells
Stem Cell Research - Transit amplifying cells have crucial role in epidermal growth control
Stem Cell Therapy - Olfactory sensory neurons proliferated by leukemia inhibitory factor
Stem Cell Transplantation - Cord blood better than haploidentical mobilized PBL for sustained engraftment
Stem Cell Transplantation - NST yields durable response in minority of metastatic renal cancer patients
Stem Cell Transplantation - Positive CMV serology may contribute to neurological complications after HSCT
Stem Cell Transplantation - Rituximab effective for refractory autoimmune cytopenias after ASCT
Stem Cell Transplantation - Stable engraftment achieved in unrelated/mismatched SCT in mucopolysaccharidosis
Stem Cell Transplantation - Steroids prevent engraftment syndrome without increasing infection risk
Stem Cell Transplantation - Two partially HLA-matched cord blood units enhance engraftment
Stem Cell Transplantation-Related Infection - Aspergillus+ blood cultures not always assoc. with invasive disease in SCT
Stem Cell Transplantation-Related Infection - Preemptive ganciclovir for CMV disease post-ASCT cost-effective/reduces toxicity
Streptococcus Vaccines - Data advance knowledge in streptococcus vaccines research
Stroke - Atorvastatin restores brain function after cerebral infarction
Surgical Technology - Out-of-hospital thromboprophylaxis not needed after laparoscopic surgery
Survivin - p21(Ras) studied, influence of survivin in human fibroblasts revealed
Tetanus Vaccine - Infectious disease group says tetanus boosters needed age 11 throughout life
Thyroid Cancer - Silencing of tumor suppressor ARHI contributed to thyroid carcinogenesis
Tissue Engineering - Fiber-based tissue engineered scaffold designed for ligament replacement
Tissue Engineering - Hydrogel scaffold developed for cell adhesion and neural outgrowth
Tissue Engineering - Hydrogel scaffolds containing angiogenic cytokine direct cell migration
Tissue Engineering - RGD peptides/FBS regulate MSC attachment/spreading on hydroxyapatite
Tobacco Use - Prostop laser therapy provides successful method to quit smoking
Transplant Medicine - Chemoattractant protein studied, role in murine islet transplantation revealed
Transplant Medicine - Donor age has no effect on long-term liver transplant survival
Transplant Medicine - Genetically modified T cells mitigate graft versus host disease
Transplant Medicine - Kidney transplant recipients experience hepatitis B virus reactivation
Transplant Medicine - Studies describe new findings in transplant medicine research
Trends - Double-digit growth projected for sleep service provider markets
Tuberculosis - Mycobacterium tuberculosis proteasomal ATPase homologue characterized
Tuberculosis - CSF induced by 30-kDa secretory protein of Mycobacterium tuberculosis H37Rv
Tuberculosis - Magnetic resonance spectroscopy diagnoses cerebral TB from neurocysticercosis
Tuberculosis - Phagosomal elemental concentration change by M. tuberculosis Mramp described
Tuberculosis - Regulatory sequence recognized by M. tuberculosis MprA identified
Tuberculosis - Scientists study the basis of resistance to capreomycin
Urinary Incontinence - Side effects of current drug therapies for stress UI limit their use
Urological Disease - Research studies link Nanobacteria infection to urological diseases
Vaccine Development - Engineered CD40 receptor enables activation of DC cancer vaccines in vivo
Vaccine Development - Lipopolysaccharide eclipses hepatitis B virus nucleocapsid immunogenicity
Vaccine Development - RiVax maker reports revenues for 2004 of $997,482, all recognized in Q4
Vaccines Adjuvant - Researchers detail new studies and findings in the area of vaccines adjuvant
Vaccines Delivery - Researchers publish new studies and findings in the area of vaccines delivery
Vector Development - Hypoxia-inducible expression vector directs cancer gene therapy
Vector Development - Recombinant viral capsids are efficient oligonucleotide delivery vehicles
Vector Development - Researchers report details of new studies and findings in the area of vector development
Virology - Banna virus outer coat protein VP9 studied, structure and function reported
Virology - Delta24-hyCD adenovirus uses oncolysis and chemosensitization to fight glioma
Virology - Hepatitis B genotype D often causes acute liver failure
Virology - Hepatitis C virus protein mutations fuel antiviral resistance
Virology - Modified adenoviruses may not yield anticipated results in in vivo research
Virology - Molecular beacons quantify lamivudine-resistant hepatitis B virus mutants
Virology - Molecular signatures distinguish adenoviruses being considered for gene vectors
Virology - New data illuminates research in virology
Virology - New solutions make retrovirus-mediated gene transfer a safer option
Virology - Newcastle disease virus selects tumor cells for gene delivery
Virology - Several factors drive the effect of donor age on liver transplant outcomes
Weight Gain Risk Factors - T allele protects against clozapine-induced weight gain in schizophrenics
West Nile Virus - Public health interventions limited in ability to deal with multiple epidemics
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