Hematopoiesis

Growth factor independence 1 is an intrinsic regulator of stem cell self-renewal

Published in Drug Week, May 13th, 2005

Growth factor independence 1 is an intrinsic regulator of stem cell self-renewal.

According to a recent report from the United States, "Hematopoiesis can be scripted into multiple acts that open with hematopoietic stem cells (HSCs) and close with the production of nonproliferating mature blood cells.

"Its lifelong durability requires that HSCs choose between mutually exclusive fates: self-renewal versus a capacity for multilineage differentiation. The growth factor independence 1 (Gfi-1) oncoprotein was first discovered playing supporting roles in lymphopoiesis and myelopoiesis."

"Two new studies indicate that Gfi-1 regulates...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Drug Week

Source: Drug Week (2005-05-13)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry