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Drug Week

Susan Hasty, Publisher
Table of Contents . . . June 17th, 2005
Non-Subscriber - Summaries Only
Related Areas: Other Issues in Drug Week | Other Publications

COX-2 Expression - Ginseng extract examined, effect on macrophage COX-2 expression defined

Cancer Therapy - Phase II results presented on Perifosine for prostate cancer

Drug Development - Phase III data show potential for earlier treatment of kidney disease

Drug Development - Phase Ib/II trial with ADH-1 initiated in advanced cancer patients

Drug Development - Supplemental BLA submitted to U.S. FDA for Aranesp extended dosing

Prostate Cancer - Data: Provenge significantly improves survival in advanced prostate cancer

Acute Myeloid Leukemia - New findings in acute myeloid leukemia described

Addiction Medicine - Mixed hepatitis C genotypes in injection drug users cut antiviral efficacy

Addiction Medicine - Vaccine to treat nicotine addiction earns proof of efficacy in phase 2 trial

Age Related Macular Degeneration - Company announces positive interim EVIZON phase II AMD data

Age Related Macular Degeneration - Photo-oxidative events elicit threats to retinal pigment epithelial cells

Allergy & Immunology - Allergy organization reminds of the danger of stinging insect allergies

Angiology - Recent studies add new data to angiology research

Allergy & Immunology - Scientists demonstrate how airborne fungal fragments contribute to allergies

Alzheimer Disease - Beta-site specific intrabodies prevents generation of Alzheimer A beta peptide

Alzheimer Disease - Chronic melatonin therapy not effective in murine model

Alzheimer Disease - Gene therapy company licenses gene from university

Alzheimer Disease - Research in Alzheimer disease provides new insights

Anaphylaxis - C-kit mutation detected by real-time PCR in patients with anaphylaxis

Breast Cancer - Researchers publish new studies and findings in the area of breast cancer

Angiology - Cypher Sirolimus-eluting coronary stent data featured at meeting

Angiology - Ezetimibe/simvastatin is an efficacious and tolerated treatment

Angiology - Impedence cardiography effective for reducing blood pressure, study shows

Angiology - Laser-made channels and progenitor cells spawn new vessels in ischemic limbs

Angiology - Recent findings illuminate research in angiology

Cancer Therapy - Researchers publish new studies and findings in the area of cancer therapy

Angiology - The proliferating endothelium expresses select somatostatin receptors

Angiotensin - AT receptor orthologues studied, species functional diversity revealed

Angiotensin Converting Enzyme - ACE inhibitors are better taken in the evening

Anti-infectives - Biodegradable antibiotic-releasing catheter polymer developed

Antibiotic Resistance - Pathogens can have a strong effect on host behavior

Anticoagulant Therapy - Dalteparin doesn't influence lupus anticoagulant test results

Cardiology - New research in the area of cardiology detailed

Antimicrobial Resistance - Ciprofloxacin-resistant Pseudomonas aeruginosa investigated

Antioxidants - Mistletoe extracts possess antioxidant activity in diabetic rats

Antipsychotic Therapy - Novel HPLC assay facilitates ziprasidone monitoring

Antiviral Therapy - Entecavir prevents viral persistence after duck hepatitis B infection

Antiviral Therapy - Findings advance knowledge in antiviral therapy research

Aplastic Anemia - Third course of ATG for aplastic anemia an option only for previous responders

Cardiology - Recent studies add new data to cardiology research

Arrhythmia - Electrical storm is an independent predictor of poor outcome in ICD patients

Arthritis - Loci on chromosomes 10 and 17 determine autoimmunity, arthritis susceptibility

Asthma - Pharma company submits application to market Aridol in Europe

Asthma - Research finds obese people incorrectly diagnosed with asthma

Astrocytoma - Prognostic factors of incompletely excised gemistocytic astrocytomas determined

Atherosclerosis - Intravascular ultrasound system for atherosclerosis diagnosis introduced

Cardiology - Research in cardiology provides new insights

Atherosclerosis - New findings in the area of atherosclerosis detailed

Atrial Fibrillation - Catheter ablation compared to AV junction ablation w/ pacing therapy

Attention Deficit Hyperactivity Disorder - Strattera now more widely available in Europe

Autoimmune Disease - Companies sign agreement to develop 2 novel treatments for autoimmune diseases

Avian Influenza - Alferon LDO in trials as experimental antiviral therapy

Awards - CSO Rino Rappuoli, PhD, elected to U.S. National Academy of Sciences

Cardiology - Researchers' data advance cardiology research

Awards - Three oncology practices receive Clinical Trial Participation Award at meeting

Bacteriology - Biacticap is the latest weapon in the fight against MRSA

Bacteriology - Recent findings in bacteriology described

Barrett Esophagus - Positive safety and efficacy data released for Halo360 system treatment

Benign Prostatic Hyperplasia - Positive results from study of drug in benign prostatic hyperplasia reported

Biochemistry - Novel chip-based assay facilitates analysis of natural flavonoids

Cardiology - Researchers' work adds to cardiology body of knowledge

Biomedical Engineering - Consensus shuffling corrects errors in synthetic DNA

Biomedical Engineering - Re-engineered autologous T cells attack non-Hodgkin lymphoma cells

Biomedical Engineering - Self-assembling peptides form scaffolds for creating vascularized tissue

Biotechnology - Further phase II data confirm panitumumab single-agent antitumor activity mCRC

Bladder Cancer - Vascular, lymphatic, and perineural invasion prognosticated bladder cancer

Bloodstream Infection - Categorization and blood culture Gram stains can guide early treatment

Diabetes Pathogenesis - Findings describe new data in diabetes pathogenesis research

Brain Cancer - Fos-related antigen 1 enables glioma to maintain a malignant phenotype

Brain Cancer - New treatment addresses incurable recurring form of adult gioblastoma

Brain Cancer - Radioactive isotope is effective against neuroblastoma

Brain Metastases - Treatment modalities and survival outcome of brain metastases discussed

Breast Cancer - Antibody drug's ability to select breast cancer patients for therapy reported

Breast Cancer - Avastin plus chemotherapy showed doubling of time without cancer progression

Diabetes Pathogenesis - New findings in diabetes pathogenesis described

Breast Cancer - Cyclooxygenase-2 expression rises in ductal carcinoma in situ

Breast Cancer - Data presented on circulating tumor cells in metastatic breast cancer

Breast Cancer - Data: Femara helped reduce risk of breast-cancer recurrence an additional 19%

Breast Cancer - Data: Tarvacin equivalent plus docetaxel inhibits breast tumor growth by 93%

Breast Cancer - Effects of cancer therapy agents altered by herbal medicine black cohosh

Breast Cancer - Gemcitabine used as salvage chemotherapy in pretreated metastatic breast cancer

Diabetes Pathogenesis - Recent findings in diabetes pathogenesis described

Breast Cancer - HER-2 overexpression inversely correlates with ER/PR expression in breast cancer

Breast Cancer - Multiple studies on breast cancer presented at clinical oncology meeting

Breast Cancer - New research in the area of breast cancer detailed

Breast Cancer - Survival data on drug in phase 3 trial for metastatic breast cancer reported

Breast Cancer - Zometa reduces bone loss in patients receiving breast cancer treatment

Diabetes Pathogenesis - Researchers describe findings in diabetes pathogenesis studies

Business & Finance - ATP-focused company reports Q1 net loss of $447,622

Business & Finance - Biopharmaceutical firm reports loss of $0.40 per share, provides clinical update

Business & Finance - Cell-focused technology company reports third quarter 2005 financial results

Business & Finance - Company focused on lipids-associated diseases reports Q1 2005 results

Business & Finance - Company focused on regenerative medicine therapies reports Q1 2005 results

Business & Finance - EVIZON developer reports Q1 net loss of $5.3 million

Diabetes Therapy - Research add new data to diabetes therapy body of knowledge

Business & Finance - GI-focused biopharmaceutical company completes $32 million financing

Business & Finance - Laboratory reports record year-end sales and earnings

Business & Finance - Managed care company announces 2005 first quarter operating results

Business & Finance - Pharma firm reports $0.23 per share loss, provides update on sarcoma drug

Business & Finance - Pharma firm reports 65% increase in revenue, provides clinical update

Business & Finance - Pharma firm reports on royalty stream from Rotarix

Diabetes Therapy - Researchers describe findings in diabetes therapy studies

Business & Finance - Pharmaceutical company signs branded, generic drug agreements, reports on Q4

Business & Finance - Pharmaceutical development company announces first quarter results

Business & Finance - Prochieve maker reports Q1 revenues of $4.3 million

Business & Finance - Provenge maker reports Q1 revenues of $57,000

Business & finance - Biology corporation retains Macias Gini & company LLP as independent auditors

Business Update - Biopharma company changes name to Avidimer Therapeutics

Diabetes Therapy - Researchers publish new studies and findings in the area of diabetes therapy

Business Update - Biopharmaceutical firm adopts shareholder rights plan

Business Update - Biopharmaceutical firm establishes Canadian operations

Business Update - Biosystems Informatics Institute establishes commercial trading arm

Business Update - Book takes on questions facing today's healthcare industry

Business Update - Clinical research organization adds neurobehavioral unit

Business Update - Company acquires rights for 16 cancer targets from Europroteome

Insulin Resistance - Researchers' work adds to insulin resistance body of knowledge

Business Update - Company extends Sirtuin patent portfolio; signs exclusive IP license agreement

Business Update - Company reports on expiration of peptide agreement

Business Update - Diversified services company appointed placement agent for national drug chain

Business Update - Drug discovery company to include microdosing automation at Florida plant

Business Update - Immunotherapeutics company provides update on operations, corporate developments

Business Update - Life science technologies company chairman and CEO adopts 10b5-1 Plan

Liver Cancer - Researchers' findings advance liver cancer research

Business Update - Makeover corporation delivers on site medical services at Florida facility

Business Update - Medical isotope company considers relocation of production facilities to Idaho

Business Update - Orders of Sucanon diabetes drug shipped to Wal-Mart

Business Update - Pharma firm inaugurates new manufacturing space

Business Update - Pharma firm's chairman and CEO resigns, company withdraws guidance

Business Update - Pharmaceutical firm reports changes in corporate governance

Melanoma Vaccines - New research in the area of melanoma vaccines detailed

Business Update - T-cell epitope identification addressed for Asia

Cancer Research - Biopharma company released results for NeoLipid clinical trial

Cancer Research - Combretastatin A4 Prodrug trial indicates antitumor activity

Cancer Research - Epothilone ZK-EPO trial results presented at conference

Cancer Research - Interim phase I results for SB-743921 reported at ASCO meeting

Cancer Research - MARINOL helps to reduce delayed chemotherapy-induced nausea and vomiting

Neuroscience - Researchers' data advance neuroscience research

Cancer Research - Toxicity testing in mice for PhG-alpha-1 complete

Cancer Therapy - A causal link has been found between lymphopenia and autoimmunity

Cancer Therapy - Acapodene reduced prostate cancer incidence in high-risk men

Cancer Therapy - Anticancer effects of STAT-3 inhibitor demonstrated

Cancer Therapy - Biopharmaceutical company announces positive results of cancer treatment

Cancer Therapy - Blocking the Odc gene is effective in preventing certain cancers

Osteoporosis - Reports advance knowledge in osteoporosis research

Cancer Therapy - Canaxin induces antibody responses to protein, glycolipid tumor antigens

Cancer Therapy - Clinical trial results presented for trifunctional antibodies

Cancer Therapy - Companies announce agreement with NCI for PXD101

Cancer Therapy - Companies announce presentation of PXD101 phase I results at ASCO

Cancer Therapy - Company presents additional HuMax-EGFr phase I/II efficacy data at ASCO

Cancer Therapy - Data from Tarceva clinical trial program presented at meeting

Osteoporosis - Research add new data to osteoporosis body of knowledge

Cancer Therapy - Data presented on Targretin lung cancer trials

Cancer Therapy - Data: ECO-4601 also effective against breast and prostate cancer

Cancer Therapy - Favorable data presented from two KOS-862 phase IB trials

Cancer Therapy - Initial phase II findings from HuN901-DM1 trial reported

Cancer Therapy - Lower doses of chemotherapy equally effective in most children

Cancer Therapy - Methods could make new treatments available more quickly

Proteomics - Recent findings illuminate research in proteomics

Cancer Therapy - Oral talactoferrin improved response rates in lung cancer

Cancer Therapy - Pathology and time factors decide outcomes of second liver cancer resections

Cancer Therapy - Positive early phase II results reported on advanced sarcoma therapy

Cancer Therapy - Positive phase II results reported on AS1404 in prostate cancer

Cancer Therapy - Positive results reported from phase II study of Teverelix in prostate cancer

Cancer Therapy - Researchers detail new studies and findings in the area of cancer therapy

Proteomics - Reports add new data to proteomics research

Cancer Therapy - Results for phase I trial of IMOxine presented at cancer meeting

Cancer Therapy - Waiting period expiring for CPG 7909 licensing agreement with Pfizer

Cancer Vaccines - New findings in the area of cancer vaccines described

Carcinoid Syndrome - Once-monthly somatostatin analogue increases survival in Carcinoid Syndrome

Cardiac Stem Cell Research - Directing cardiac fate in stem cells is necessary for regeneration

Vector Development - Researchers provide details of new studies and findings in the area of vector development

Cardiology - Aldosterone improves hepatic hemodynamics; needs help with cardiac issues

Cardiology - Drug-coated cardiovascular stent technology may increase safety, efficacy

Cardiology - Hibernating cardiac cells respond favorably to fibroblast growth factor-5

Cardiology - Inpatient lipid lowering therapy saves lives

Cardiology - New data illuminates research in cardiology

Virology - Reports advance knowledge in virology research

Cardiology - Potency of metoclopramide to block HERG currents lower than that of domperidone

Cardiology - Simvastatin and pravastatin treatment attenuates cardiac/kidney remodeling

Virology - Research add new data to virology body of knowledge

Cell Biology - GRP78/BiP protects human RSa cells against DNA damage

Cell Proliferation - Adrenocortical cell proliferation examined, effects of met-enkephalin revealed

Cell Signaling - Mitogen-activated protein kinase studied, role in cell survival signaling shown

Chemotherapy - Feasibility of individualized chemotherapy treatment for breast cancer analyzed

Chemotherapy - Single-agent chemotherapy used for posttransplant lymphoproliferative disorder

Cholangiocarcinoma - U.S. FDA approves compassionate use IND for DAVANAT/5-FU

Chronic Hepatitis B - Lamivudine therapy lowers hepatitis B covalently closed-circular DNA levels

Chronic Hepatitis C - Researchers' data advance chronic hepatitis c research

Chronic Liver Disease - Body mass raises non-alcoholic steatohepatitis risk in chronic hepatitis C

Chronic Liver Disease - Hepatocyte apoptosis is routine in chronic hepatitis C despite normal ALT

Chronic Liver Disease - TT virus coinfection accounts for some liver disease cases in India

Chronic Obstructive Pulmonary Disease - N-acetylcysteine treatment ineffective for COPD patients

Clinical Trials - Company reports CYC682 phase I data at 2005 ASCO

Clinical Trials - Stomach acid control of proton pump inhibitors in chronic NSAID users compared

Collaborations - Agreement signed for marketing rights to Sanctura

Collaborations - Alliance formed to advance clinical genomics for personalized medicine

Collaborations - Alliance formed to develop, commercialize Phenoptin and Phenylase

Collaborations - Biotech company expands project with Pfizer Inc.

Collaborations - Biotech company teams with Mayo Clinic to develop antibodies

Collaborations - Biotechnology company announces collaboration with pharmaceutical company

Collaborations - Cell line engineering alliance signed

Collaborations - Companies finish first stage of proof of concept study for Melanotan/BioSilicon

Collaborations - Companies sign partnership to help with drug approvals in China

Collaborations - Company extends strategic alliance with Allergan

Collaborations - Contract manufacturing organization and University of Maryland partner

Collaborations - Deal signed for French distribution of ion channel drug discovery system

Collaborations - Deal signed for development of gene therapy for hemophilia

Collaborations - Deal signed to create an anti-obesity nasal spray

Collaborations - Development, license, supply agreement signed for Oxygent

Collaborations - Geisinger inks initiative to reduce CVD, improve patient care

Collaborations - Licensing deal signed for human oncology antibodies

Collaborations - Manufacturing agreement reached for production of VEGF-2 plasmid DNA

Collaborations - Pharma company and Lexicon Genetics collaborate to develop biotherapeutic drugs

Collaborations - Pharma company announces collaboration for provision of chemistry services

Collaborations - Pharma firm gains access to Asian markets through joint venture

Collaborations - Pharmaceutical companies collaborate on using microalgae in protein expression

Collaborations - Progress reported in deal to develop cancer therapies

Collaborations - Research deal signed with National Cancer Institute

Collaborations - Third oral drug delivery research deal announced

Colon Cancer - Erbitux may fight colorectal cancer after other therapies fail

Colon Cancer - Lessons from TRAIL-resistance mechanisms paved road to patient-tailored therapy

Colon Cancer - Mast cell numbers shed light on colorectal cancer angiogenesis and recurrence

Colon Cancer - Microsatellite instability associated with sporadic colon cancer

Colorectal Cancer - Abstracts show safety, efficacy of SIR-Spheres with new chemotherapy

Colorectal Cancer - Trial shows high response to colorectal cancer drug may bring curative surgery

Complementary & Alternative Medicine - Ganoderma lucidum cuts off angiogenic signaling in prostate cancer

Complementary & Alternative Medicine - Korea red ginseng water extract shows potential as hypertension treatment

Complementary & Alternative Medicine - Salvia miltiorrhiza extract shows promise in heart disease prevention

Congenital Heart Disease - Hyperbaric oxygen should be used promptly for CAGE in congenital heart disease

Congestive Heart Failure - Company announces extended phase II results for Furosemide GR

Contraception - Antiangiogenic agents disrupt ovarian function in non-human primates

Contraception - Reports describe recent advances in contraception research

Critical Care Medicine - Smart infusion pumps detect intravenous medication errors

Crohn Disease - New phase III data of HUMIRA trial reported at conference

Crohn Disease - Small, open-label study shows potential use of antibiotic

Cystic Fibrosis - Growth hormone therapy safe and effective for adolescent patients

Cytomegalovirus - Findings describe new data in cytomegalovirus research

DNA Research - Company acquires license for therapy to treat cancer of central nervous system

Depression - Bryostatin analyzed, dual effects on spatial memory and depression revealed

Depression - Certain acne treatment does not increase symptoms of depression in adolescents

Depression - New findings in depression described

Dermatology - Id2 helps skin cells recover from radiation exposure

Diabetes Complications - Pigment epithelium-derived factor prevents diabetic retinopathy progression

Diabetes Pathogenesis - Findings advance knowledge in diabetes pathogenesis research

Diabetes Prevention - Blood pressure drug cuts risk of diabetes

Diabetes Risk Factors - Risperidone-associated type 1 diabetes reported

Diabetes Therapy - Fomes fomentarius supplement corrects hyperglycemia

Diabetes Therapy - Community pharmacy program improves aspirin use in diabetic patients

Diabetes Therapy - Orlistat promotes weight loss and improves glycemic control

Diabetes Therapy - Pioglitazone reduces antioxidative system changes in diabetes

Diabetes Therapy - Reports advance knowledge in diabetes therapy research

Diabetic Foot Ulcers - Data presented on treatment for diabetic foot ulcers

Diabetic Nephropathy - Interim results positive from phase 2 study for diabetic nephropathy treatment

Diagnostics - Asymptomatic patients with anti-hepatitis C antibody harbor HCV RNA

Diagnostics - Companies announce agreements for new cystic fibrosis assay

Diagnostics - Gamma-glutamyltransferase marks excess liver activity in hepatitis C patients

Diagnostics - New microparticle enzyme immunoassay measures sirolimus

Diet & Nutrition - In vitro and in vivo antitumor effects of vitamin K5 on liver cancer described

Diet & Nutrition - Mediterranean diet increases survival in heart disease patients in Greece

Diet and Nutrition - Dietary changes improve the histology of non-alcoholic steatohepatitis patients

Diet and Nutrition - New cognitive health supplement introduced

Diet and Nutrition - Nutraceuticals company testing appetite suppressing candy chew

Dietary Supplements - Seizures reported in association with use of dietary supplements

Disease Associations - Prothrombogenic inflamed colonic phenotype studied, molecular nature defined

Disease Outbreaks - Vaccine shortages reflect problems in pharmaceutical industry, doctor says

Dopamine - Dopamine transporter examined, behavior effect of downregulation revealed

Drug Abuse - COX-2 mediates methamphetamine-induced neurotoxicity

Drug Allergy - In vitro test facilitates diagnosis of delayed hypersensitivity reactions

Drug Delivery - A peptide vector-mediated strategy improves morphine-6-glucuronide uptake

Drug Delivery - Aerosol alpha-tocopherol may help control inflammatory lung illnesses

Drug Delivery - Carboxy methyl dextran hydrogel is pH- and ionic-strength-sensitive

Drug Delivery - Encapsulated ceramide injected into bloodstream of mice kills cancer cells

Drug Delivery - New method of administering anticancer drug may be more effective, safer

Drug Delivery - PEG/PLA semiinterpenetrating network controls delivery of protein drugs

Drug Delivery - Recombinant adenovirus vector expresses IL-2 and myelomonocytic growth factor

Drug Delivery - Results reported for intranasal vaccine delivery technology

Drug Delivery - Ultrasound radiation helps nanoparticles penetrate tumors

Drug Development - Access provided for Sorafenib for patients with advanced renal cell carcinoma

Drug Development - Antifungal agent Mycamine available to physicians

Drug Development - Antifungal agent derived from Streptomyces albidoflavus PU 23

Drug Development - CaP nanotechnology review presented at immunopotentiators meeting

Drug Development - Candidate drug against HIV/AIDS approved to enter clinical trials in U.K.

Drug Development - Company licenses MetaCore to Exelixis

Drug Development - Data presented from phase III miconazole Lauriad Bioadhesive study

Drug Development - Data reported from phase III trial of Insegia in pancreatic cancer

Drug Development - Data show significant reduction in incidence, severity of autoimmune myocarditis

Drug Development - Evidence of antitumor activity in phase I trial of ARQ 501 reported

Drug Development - Immunodrug candidate CAD106 for Alzheimer disease gets Swedish clearance

Drug Development - Lung cancer drug maker provides clinical pipeline update

Drug Development - Lupin enters development and licensing agreement

Drug Development - Marqibo clinical data presented at medical meetings

Drug Development - Mechanistic basis of enzyme-targeted drugs described

Drug Development - Neuroscience company reports $2,648,000 net loss for quarter ended March 31

Drug Development - Novel indolinone A-432411 shows promise as antitumor agent

Drug Development - Pharmaceutical company expands technology platform

Drug Development - Phase 1 study of organic arsenic for blood, bone marrow cancers set to begin

Drug Development - Phase I results of Coramsine trial reported at meeting

Drug Development - Positive bone repair results reported in clinical feasibility trial

Drug Development - Positive preclinical efficacy data for GI therapeutic presented at meeting

Drug Development - Results of phase I trials of HGS-ETR2 and HGS-ETR1 reported

Drug Development - Safety data presented on product to prevent RSV in high-risk infants

Drug Development - U.S. FDA grants approval for doxycycline hyclate tablets

Drug Development - VEGF trap combination study initiated by pharmaceutical companies

Drug Development - Visicol tablets associated with fewer calls to doctors than liquid form

Drug Monitoring - Biological fluid pH strongly affects fluorometric dipyridamole assessment

Drug Research - Mizoribine and interferon unite to fight hepatitis C virus infection

Drug Research - Oral lenalidomide demonstrates antiangiogenic and antimigratory properties

Drug Resistance - FDA grants monthly WBC monitoring for FazaClo

Drug Resistance - Researchers' findings advance drug resistance research

Drug Safety - Foundation partners with U.S. FDA to promote safe use of OTC medications

Drug Toxicity - Animal-based testing for birth defects accurate only half the time

Embryonic Stem Cell Research - Autogeneic feeder cell system supports growth of undifferentiated ESCs

Embryonic Stem Cell Research - ESC ectopic mTERT expression confers resistance to p53-dependent apoptosis

Embryonic Stem Cell Research - Identified growth factors allow direct hepatic fate-specification from ESCs

Embryonic Stem Cell Research - Matrigel used as substrate for feeder-free propagation of undifferentiated ESCs

Embryonic Stem Cell Transplantation - ESC-derived microglia-like cells migrate into brain but not peripheral tissues

Endocrinology - Incretin-based therapies may offer new benefits in glucose control

Endocrinology - Recent findings in endocrinology provide new insights

Endocrinology - Tamoxifen raises the risk for fatty liver disease in healthy overweight women

Enzymology - Matrix metalloproteinase-2 is inessential for retinal neovascularization

Enzymology - Matrix metalloproteinases mark chronic hepatitis C-related liver fibrosis

Enzymology - Researchers report details of new studies and findings in the area of enzymology

Enzymology - Subtilase PCSK9 examined, role in cholesterol level and statins revealed

Epilepsy - Intravenous valproate is a valid therapy in seizure emergency situations

Epithilial Cells - Potentiation of ATP-induced Ca²⁺ mobilization in retinal cells studied

Female Sexual Arousal Disorder - Efficacy data reported for topical cream treatment

Fibromyalgia - Patients may benefit from cough remedy

Finance - Biomedical company reports 19% increase in product sales

Finance - Biometrics company announces financial results

Finance - Biopharmaceutical company announces first quarter 2005 results

Finance - Biopharmaceutical company announces third quarter fiscal 2005 financial results

Finance - Biopharmaceutical company closes series A financing

Finance - Biopharmaceutical company reports 35% increase in revenue

Finance - Biopharmaceutical company reports loss of $0.05 per share

Finance - Biopharmaceutical company reports loss of $0.16 per share

Finance - Biopharmaceutical company selected to join NASDAQ Biotechnology Index

Finance - Biosystems company announces revenue increase and second quarter earnings

Finance - Biotech company completes first institutional financing

Finance - Biotech company records 60% increase in revenue

Finance - Biotech company records 63.4% increase in revenue

Finance - Biotech company records loss of $0.64 per share

Finance - Biotech company reports loss of $0.05 per share

Finance - Biotech company reports loss of EUR 0.6M

Finance - Cardiovascular-focused pharmaceutical company announces Q3 2005 results

Finance - China-based nutrition, personal care products company reports Q1 2005 results

Finance - Chromium-based nutritional supplement provider reports financial results

Finance - Clinical trials company reports Q1 net revenue of $3.2 million

Finance - Company secures $65.2M to drive clinical development of targeted oncology drugs

Finance - Company secures new $2.5M financing to complete IND and begin MDRTB trials

Finance - DNA analysis tools provider reports first quarter 2005 financial results

Finance - Drug maker reports loss of $0.02 per share

Finance - Endocrine-focused biopharmaceutical company added to NASDAQ Biotechnology Index

Finance - Genasense maker reports Q1 revenues of $18.5 million

Finance - Holding company reports financial results

Finance - Laboratory reports fiscal 2005 earnings

Finance - Maker of cell-targeted therapeutic products applies for AMEX listing

Finance - Multiple sclerosis drug developer reports loss of $0.05 per share

Finance - NASDAQ announces semi-annual changes to biotechnology index

Finance - Nuclear medicine producer reports 7.7% decrease in revenue

Finance - Oncology company reports 6.4% increase in revenue

Finance - Ophthalmic therapeutics maker reports loss of $0.06 per share

Finance - Pennsylvania governor awards biotech grant

Finance - Pet pharmacy company announces financial results

Finance - Pharma company reports first quarter financial results

Finance - Pharma firm authorizes $450M share repurchase program

Finance - Pharma firm records 46% increase in revenues

Finance - Pharma firm reports 5.6% decrease in revenue

Finance - Pharma firm reports loss of $0.46 per share, provides drug pipeline update

Finance - Pharma firm reports reduction in net income

Finance - Pharmaceutical company announces stockholder approval of share exchange

Finance - Pharmaceutical company focused on cyclic mastalgia reports Q1 2005 results

Finance - Pharmaceutical company records per share loss of $0.32

Finance - Pharmaceutical company reports $0.19 per share loss

Finance - Pharmaceutical company reports fiscal year 2004-05 global sales up by 16%

Finance - Pharmaceutical company reports loss of $0.32 per share

Finance - Pharmaceutical company reports record first quarter sales

Finance - Pharmaceutical firm joins NASDAQ Biotechnology Index

Finance - Pharmaceutical firm raises additional $11.8M

Finance - Pharmaceutical firm reports 29% increase in net loss

Finance - Pharmaceutical firm reports loss of $0.82 per share

Finance - Pharmaceutical firm retires NeoPharm promissory note

Finance - Pheromone developer reports 51% decrease in sales

Finance - RNAi company reports Q1 net loss of $3.5 million

Finance - Reducol maker reports Q1 revenue of $4.72M

Finance - Specialty-pharmaceutical company to be added to the NASDAQ Biotechnology Index

Finance - Stem cell research grants offered

Finance - Technology receives milestone payment from Novo Nordisk

Finance - Tennessee branded pharmaceutical company reports first-quarter 2005 results

Finance - U.S. NIH grant will help develop infection fighting protein

Finance - Vitex Files Shelf Registration Statement

Finance - Wound-care products company announces 3% dip in Q1 sales

Financing - Medical device company raises $9.65 million in new financing

Gastric Cancer - Chemotherapy regimen demonstrates survival benefits in advanced gastric cancer

Gastric Cancer - LERGU mutation or deletion implicated in gastric cancer

Gastroenterology - Data advance knowledge in gastroenterology research

Gastroenterology - Hepatic arterial infusion chemotherapy treated sarcoma liver metastases

Gastroenterology - One side effect of SERMs may be prevention of gallstones

Gastroenterology - Phase IA study completed in irritable bowel syndrome treatment

Gastroenterology - Specific fatty acids improve liver fibrosis in high cholesterol models

Gastrointestinal Cancer - Biopharma company releases data from studies in gastrointestinal cancers

Gastrointestinal Stromal Tumors - SUTENT/SU11248 extends overall survival in Gleevec-resistant GIST

Geldanamycin - Novel anti-geldanamycin antibody generated

Gene Delivery - Stealth liposomes transport genes to breast cancer cells

Gene Research - Genomics research institute licenses high throughput gene-mining platform

Gene Research - Long and short oligonucleotide arrays find overlapping gene sets

Gene Research - Monozygotic twin gene profiles reveal natural variations in gene expression

Gene Research - RNA polymerase II construct makes short hairpin RNA and provokes gene silencing

Gene Silencing - Studies add new findings to gene silencing body of knowledge

Gene Transfer - Researchers' findings advance gene transfer research

Generic Drugs - Pharma company to exit proprietary business, focus will be generics

Generic Drugs - Trade group: USP monograph shows support for generic biopharmaceuticals

Genetics & Genomics - Gene expression studied to determine causes of tumor progression

Genetics & Genomics - Gene variants associated with progressive liver disease risk are identified

Genetics & Genomics - New genomic assays launched for real-time gene expression analysis

Genital Herpesvirus Prevention - Topical microbicides being developed to prevent genital herpes infection

Gingivitis - Novel chlorhexidine formulation has reduced side effects

Glycemic Control - Amylin and glucagon dampen glycemic excursions in type 1 diabetes

Grants - Cancer center awarded $14.4 million NCI grant for tumor vascular targeting

Gynecology - COX-2 inhibitors show therapeutic potential against uterine endometrial cancer

Gynecology - Endometrial cancer developed following radiation therapy for cervical carcinoma

Gynecology - Uterine cancer genetic fingerprints shape diagnosis and treatment

HIV/AIDS Costs - Full cost of HIV/AIDS treatment revealed in study

HIV/AIDS Diagnostics - Dried blood spots improve access to HIV diagnosis in infants

HIV/AIDS Diagnostics - One-step nested PCR monitors HIV replication

HIV/AIDS Diagnostics - Rapid HIV testing has reduced test results from days to minutes

HIV/AIDS Drug Development - Developed HIV-1 protease inhibitors active against multidrug-resistant virus

HIV/AIDS Drug Development - Developed tricyclic phtalimide analogues inhibit HIV-1 integrase

HIV/AIDS Drug Development - Low molecular weight HIV-1 protease dimerization inhibitors developed

HIV/AIDS Drug Development - Lysozyme nonapeptide HL9 has anti-HIV activity

HIV/AIDS Drug Development - Method predicts structure-based activity of HIV-1 RT inhibitors

HIV/AIDS Drug Resistance - Antiretroviral resistance not a major determinant of disease progression/death

HIV/AIDS Epidemiology - HIV infection rate not significantly changed among adolescents in South Africa

HIV/AIDS Epidemiology - Multiple partners and unprotected sex fuel HIV/AIDS epidemic in Africa

HIV/AIDS HAART - Adverse experiences increased following quadruple-drug induction HAART

HIV/AIDS Nutrition - Fruit/vegetable increase improves oxidative stress indicators in HIV/AIDS

HIV/AIDS Pathogenesis - CD4 engagement-induced cell surface rearrangement facilitates HIV entry

HIV/AIDS Pathogenesis - CD81 increases HIV-1 gene expression in CD4 cells via transcription factors

HIV/AIDS Pathogenesis - HIV Gag concentrates in specific plasma membrane areas rapidly after translation

HIV/AIDS Pathogenesis - HIV-1 gp120 regulates cxcr4-mediated signaling in neural progenitor cells

HIV/AIDS Pathogenesis - HIV-1-induced macrophage gene expression includes the p21 gene

HIV/AIDS Pathogenesis - HIV-1-specific CTL responses in blood mirror mucosa in natural chronic infection

HIV/AIDS Pathogenesis - JM4 is a four-transmembrane protein binding to CCR5 receptor

HIV/AIDS Pathogenesis - Kinetic factors control HIV-1 cell entry efficiency/entry inhibitor efficacy

HIV/AIDS Pathogenesis - Rad3-related protein and GADD45 alpha mediate HIV-1 Vpr-induced apoptosis

HIV/AIDS Pathogenesis - TFII-I regulates induction of HIV-1 LTR in cooperation with USF

HIV/AIDS Pathogenesis - TNF-alpha stimulates HIV-1 production in adipocytes

HIV/AIDS Prevention - Most rural health institutions in Ethiopia report reusing needles/syringes

HIV/AIDS Prevention - Team reports progress assessing trial of HIV drug therapy in southern Africa

HIV/AIDS Prevention - Unsafe sex occurs in spite of knowledge about safe sex and consequences

HIV/AIDS Research - HIV-associated sensory neuropathy trial results announced

HIV/AIDS Research - Inverse relationship between heparin binding by HIV gp120 and its thiol content

HIV/AIDS Testing - New method discriminates between pre- and post-transcription HIV inhibitors

HIV/AIDS Therapy - Companies commit to fight AIDS in China

HIV/AIDS Therapy - HIV reverse transcriptase mutations confer drug resistance

HIV/AIDS Therapy - New research in the area of HIV/AIDS therapy detailed

HIV/AIDS Therapy - U.S. FDA grants traditional approval status to 3-medication tablet for HIV

HIV/AIDS Vaccines - Research in HIV/AIDS vaccines provides new insights

HIV/AIDS Vaccines - U.N. report on combating AIDS in developing countries recently released

HIV/AIDS Vertical Transmission - CD4 count and HIV RNA are independent risk factors for mortality after delivery

HIV/AIDS-Related Disorder - HIV-related pulmonary hypertension does not worsen with HAART interruption

HIV/AIDS-Related Infection - Acinetobacter baumannii folliculitis detected in patient with AIDS

HIV/AIDS-Related Infection - Mycobacterium peregrinum infection identified in AIDS patient

HIV/AIDS-Related Infection - Rarely diagnosed cardiac aspergillosis is fatal in HIV-infected patients

HTLV-1-Assoc. Myelopathy/Trop. Spastic Paraparesis - IFN-beta 1a benefits immune mechanisms central to HAM/TSP pathogenesis

Head & Neck Cancer - HIF-1 alpha has limited prognostic value in esophageal squamous cell carcinoma

Health Policy - Pharmacists should fill morning after pill prescriptions, survey says

Healthcare Cost - Market research firm reviews New England state's strategy to control drug costs

Healthcare Costs - Costs for cancer treatment at home or in the hospital weighed

Healthcare Costs - Growth in spending on cancer therapies nearly doubles after new oral oncologics

Healthcare Coverage - California small businesses offered more choice in insurance coverage options

Heart Failure - ACE inhibitor and PDE5 inhibitor combination improves endothelial function

Heart Failure - FDA approves Atacand for use with an ACE inhibitor to treat heart failure

Heart Failure - FDA approves heart failure indication for Frontier II system

Heart Failure - Researchers find rat useful as reference model for human chronic heart failure

Heat Shock Proteins - Heat shock protein examined, role of ATP in kinase expression revealed

Hematology - Angiogenic cytokine bolsters chronic lymphocytic leukemia

Hematology - Researchers provide details of new studies and findings in the area of hematology

Hematology - Serum endostatin mirrors angiogenesis intensity in acute myeloid leukemia

Heparin - Vascular smooth muscle proliferation studied, heparin regulation defined

Hepatitis B - Study assesses cost-effectiveness of hepatitis B drugs

Hepatitis B - U.S. Approves for the treatment of chronic hepatitis B

Hepatitis B Therapy - Interferon in combination therapy reduces hepatitis B YMDD mutant formation

Hepatitis B Therapy - Short hairpin RNA interferes with hepatitis B replication in liver cells

Hepatitis B Virus - U.S. FDA approves Pegasys for the treatment of chronic hepatitis B

Hepatitis C - Study examines two approaches for liver disease treatment

Hepatitis C Epidemiology - Hepatitis C is rarely sexually transmitted between men who have sex with men

Hepatitis C Therapy - Chinese patients with HCV genotype 1 respond better to pegylated interferon

Hepatitis C Therapy - Data presented on daily Infergen with and without ribavirin

Hepatitis C Therapy - Pegylated interferon enhances chronic hepatitis C triple therapy

Hepatitis C Virus - Hepatitis C sequences herald sustained biochemical response to interferon

Hepatitis C Virus - Ties between hepatitis C virus E2 protein and CD81 generate matrix enzyme

Herpesvirus - Studies advance knowledge in herpesvirus research

Hormone Receptors - Parathyroid hormone receptor studied, role of trafficking clarified

Hormone Replacement Therapy - Cancer risk in combined HRT users assessed in the Million Women Study

Hormones - Size of injection needle found not to affect pain level

Huntington Disease - Polyglutamine aggregates compromise gene expression in the hypothalamus

Hypercholesterolemia - Apolipoprotein B antisense lowers cholesterol without causing liver disease

Hypertension - 'White coat' effect lessened with non-drug hypertension treatment device

Hypertension - ALLHAT influence seen in physicians' prescribing patterns

Hypertension - ATHOS study results presented at geriatric conference

Hypertension - Circadian effects of telmisartan treatment must be monitored over time

Hypertension - Data on nebivolol presented at conference

Hypertension - GeneRX for Hypertension Treatment information presented at conference

Hypertension - Initiative in California raises awareness of controlling high blood pressure

Hypertension - Medical experts revisit pediatric blood pressure guidelines one year later

Hypertension - New data beta-blocker TOPROL-XL reported for pediatric hypertension treatment

Hypertension - Research in hypertension provides new insights

Hypertension - Tacrolimus encourages angiogenic growth factor production in ischemic tissues

Hypoxia - Hypoxia and anemia affected tumor biology and treatment resistance

Immunology - Complete steroid avoidance after liver transplantation yields adequate results

Immunology - Leucocytapheresis renews interferon efficacy in hepatitis C-infected patients

Incontinence - Common drug could have an additional topical effect on the bladder itself

Infectious Disease - Results presented on investigational West Nile virus vaccine

Infectious Disease Research - NIAID-supported research combats/elucidates emerging infectious diseases

Inflammatory Bowel Disease - Positive results from phase I clinical studies of Traficet-EN presented

Inflammatory Bowel Disease - Studies presented about treatment of inflammatory bowel disease

Information Technology - Clinical research software company introduces electronic messaging system

Information Technology - GPCR SARfari launched for pharmaceutical research

Information Technology - Health information technology company selected by Pathmark Stores

Information Technology - Medical society supports physicians' use of technology

Insomnia - Data: LUNESTA may be cost-effective for treating chronic insomnia

Insomnia - Study shows older adults with insomnia fall asleep faster with Ramelteon

Insulin Resistance - Researchers' data advance insulin resistance research

Kaposi Sarcoma-Associated Herpesvirus - Recent findings in kaposi sarcoma-associated herpesvirus described

Kidney Cancer - Kidney cancer therapy doubles progression-free survival in phase 3 trial

Kidney Disease - Medicare Part D coverage includes D-hormone therapy for kidney disease

Kidney Transplantation - Administration methods of antithymocyte globulins in renal transplant patients

Kidney Transplantation - Lactated Ringer's solution safer than saline for i.v. fluid therapy

Kidney Transplantation - Renal transplant recipients with mutant hepatitis B should continue lamivudine

Knee Replacement - Optimal analgesic dose of ropivacaine 0.5% for TKR determined

Leucovorin - Adjuvant 5-fluorouracil chemotherapy with or without leucovorin compared

Leukemia - Leukemia group honors researcher involved in development of children's drug

Leukemia - Survival of a child with ALL and Scedosporium prolificans infection examined

Liver Cancer - Advanced liver cancer treated with high-intensity focused ultrasound ablation

Liver Cancer - Blocking of PI3K/Akt pathway enhanced apoptosis by SN-38 induction

Liver Cancer - Findings advance knowledge in liver cancer research

Liver Cancer - Vascular indices predict liver cancer responsiveness to thalidomide

Liver Fibrosis - Rhei rhizome studied, prevention of liver fibrosis documented

Lung Cancer - M. tuberculosis infection associated with FHIT gene LOH in lung cancer

Lung Cancer - DBC1 suggested as tumor suppressor in non-small cell lung cancers

Lung Cancer - Endostatin gene therapy and radiotherapy abate lung tumor growth

Lung Cancer - Longest survival rate for patients with locally advanced lung cancer reported

Lung Cancer - Longest survival rate reported for locally advanced lung cancer patients

Lung Cancer - Monoclonal antibiody Bevacizumab trial results announced

Lung Cancer - Positive interim results of small-molecule drug, others in lung cancer reported

Lung Cancer - Preliminary data of oncology compound trials in lung cancer patients presented

Lung Transplantation - Female lung transplant recipients at greater risk of acute lung injury

Lymphocytic Leukemia - Updated analysis from trial of lymphocytic leukemia therapy reported

Lymphoma - Novel chemical classes identified as potential Pim1 inhibitors

Lymphoma - Pharmaceutical company announces phase II study results of lymphoma treatment

Lymphopenia - Link between lymphopenia and autoimmunity may be reason for treatment failure

Malaria - Pediatric antimalarial regimens compared in Tanzania trial

Malaria Therapy - Azithromycin and chloroquine effective in combination

Male Hypogonadism - Positive results from clinical trial of topical testosterone cream reported

Medical Devices - Lab results suggest catheter lock has infection-prevention attributes

Medicare - Medicare Modernization Act promises more options in health plan coverage

Melanoma - Genasense maker to file marketing authorization application in Europe

Melanoma - Maintenance biotherapy regimen slows metastatic melanoma progression

Melanoma - Results from phase II MEL 1 immunotherapy study results reported

Melanoma Vaccines - New findings in the area of melanoma vaccines described

Meningitis - Distinct lineage of echovirus 30 probable cause of aseptic meningitis outbreak

Mergers & Acquisitions - Company announces acquisition of Salmedix

Merkel Cell Cancer - Diagnosis and management strategies for Merkel cell carcinoma of skin described

Metastatic Melanoma - Pharmaceutical company presents design of phase 3 melanoma trial at ASCO

Metastatic Renal Cell Cancer - Drug significantly prolongs survival in metastatic renal cell cancer in trial

Methicillin-Resistant Staphylococcus Aureus - Soap-sharing/pre-existing cuts caused recurring MRSA infections in football team

Mitochondrial Cardiomyopathy - Mitochondrial dysfunction in heart causes disposition to arrhythmia and failure

Multiple Myeloma - Data on early administration VELCADE for multiple myeloma reported

Multiple Myeloma - Proteasome inhibitor therapy in multiple myeloma reviewed

Multiple Sclerosis - FOCIS 2005 presentation: XIAP, a novel target in multiple sclerosis

Multiple Sclerosis - Recent findings illuminate research in multiple sclerosis

Mycobacterium Smegmatis - M. smegmatis mutants unable to grow at low pH in the presence of CCCP

Mycobacterium Smegmatis - M. smegmatis re1A homolog affects cell appearance/viability/gene expression

Mycobacterium Tuberculosis - MTB mycolic acid elicits pathogen-associated host innate immune responses

Myeloid Leukemia - Phase 1 data show significant activity of drug for myeloid leukemia with ara-C

Myocardial Infarction - Comorbidities influence use of invasive techniques in MI patients

Myocardial Infarction - New study questions benefits of aspirin for the over 70s

Nanotechnology - Advances reported in nanotechnology drug delivery research program

Nanotechnology - Nanoparticle cancer therapy demonstrates promise as lung cancer therapy

Natural Products - Ethanol extract of Polygonum cuspidatum eradicates hepatitis B replication

Natural Products - Marine-derived philinopside A is both cytotoxic and antiangiogenic

Natural Products - The herbal derivative ON-III subdues angiogenesis and tumor growth

Neural Cancer - Adjuvant chemotherapy prolonged survival in adult medulloblastoma patients

Neural Stem Cell Research - Glial-derived nexin transforms HEK cells into neuron-like cells

Neural Stem Cell Research - Nandrolone influences neural stem cell proliferation and neurogenesis

Neural Stem Cell Research - P21 loss compromises adult neural stem cell relative quiescence

Neural Stem Cell Research - Simultaneous Olig2/Nkx2.2 cDNA transfection differentiates oligodendrocytes

Neuroblastoma - Chromosome deletion predicts aggressive neuroblastoma

Neurodegeneration - Reports advance knowledge in neurodegeneration research

Neurogenesis - D3 dopamine receptors do not regulate neurogenesis in subventricular zone

Neuropeptides - Neuropeptide Y examined, ethanol associated effects clarified

Neuroscience - Brain may be less plastic than hoped

Neuroscience - Magnesium sulphate protects brain tissue during neurovascular procedures

Neuroscience - Neonatal toluene exposure studied, effects on neuron NMDA receptors revealed

Neuroscience - Report evaluates emerging neurogenomics and neurotherapeutic strategies

Neuroscience - Reports describe recent advances in neuroscience research

Neuroscience - Researchers identify molecule key to CNS repair, regeneration

Neuroscience - VEGF receptor protects spinal cord motor neurons from hypoxia-induced death

Non-Hodgkin Lymphoma - Analysis shows earlier use of BEXXAR may improve treatment outcomes

Non-Small Cell Lung Cancer - Data from phase I/II study of GemVax peptide vaccine GV1001 presented

Non-Small Cell Lung Cancer - Data shows Gemzar has positive impact on survival, tumor shrinkage.

Non-Small Cell Lung Cancer - Results from oral Hycamtin trials presented at conference

Norovirus - Factors identified with bovine norovirus seropositivity in veterinarians

Norovirus Outbreaks - GII/5 was dominant genotype in norovirus outbreak in Japan

Nosocomial Infections - National medical agency grants special compassionate use for diarrhea therapy

Nuclear Magnetic Resonance - F-19 NMR is a versatile reporter for non-invasive physiology and pharmacology

Nucleopolyhedrovirus - Nucleopolyhedrovirus epizootics initiate decline of N. abietis populations

Nutrition - Copper supplementation analyzed, effects defined

Nutrition - Hippocampal formation studied, effect of prenatal protein malnutrition shown

Obesity Epidemic - Obesity epidemic is harbinger of metabolic disorder epidemic

Obesity Therapy - Anti-obesity potential of H₃ receptor antagonists/inverse agonists reviewed

Obesity and Diabetes - Researchers provide details of new studies and findings in the area of obesity and diabetes

Obsessive-Compulsive Disorder - Brain activation characterized before and after successful treatment

Obstetrics - Effects of pregnancy on maternal work tolerance studied

Obstetrics - Vaginal inserts of dinoprostone compared with cervical gel formulation

Obstructive Sleep Apnea - Obstructive sleep apnea syndrome linked to autonomic nervous system dysfunction

Oncology - Histology and angiogenesis have prognostic value in node-negative breast cancer

Oncology - Human ribonuclease inhibitor gene has antitumor effects in melanoma cells

Oncology - New findings in the area of oncology detailed

Oncology - Thalidomide enlists a multifaceted approach to treating multiple myeloma

Oncology - Transferrin-enhanced liposomes convey p53 in murine osteosarcoma models

Oncology - VEGF plays a role in breast cancer metastasis to the bone

Ophthalmology - New data illuminates research in ophthalmology

Opioid Receptors - Opioid receptors analyzed, expression in morphine-tolerant mice defined

Osteoporosis - Recent studies add new data to osteoporosis research

Ovarian Cancer - Genomics company initiates study of predictive product

Ovarian Cancer - Studies describe new findings in ovarian cancer research

Pain Management - Oral glucose increases heart rate of healthy, pain-free newborns

Pain Medicine - Choline shows promise as non-addictive analgesic

Pain Medicine - Narcotic drugs effective for severe, chronic pain in older patients

Pain Medicine - Spinal interactions between 5-HT and gabapentin or adenosine characterized

Pancreatic Cancer - Phase 3 rescue study results of 2 drugs in pancreatic cancer patients reported

Pancreatic Cancer - Randomized adjuvant therapy trials for pancreatic cancer analyzed

Pancreatic Cancer - Update on dose-escalation trial of pancreatic cancer therapy 'encouraging'

Patents - Cloning and cellular reprogramming intellectual property portfolio expanded

Patents - Japan patent granted for cyclosporin brain protection

Patents - Patent granted for mycobacterial cell wall technology

Patents - Sixteenth patent granted to biopharmaceutical firm

Patient Safety - New API provides enhanced medication image, imprint data, company announced

Pediatric Asthma Therapy - Asthmatic children in Malta show suboptimal use of spacer devices

Pediatrics - Interleukins foster hepatitis B clearance in chronically infected children

Personnel - Adrian Rawcliffe appointed managing partner and president, SR One

Personnel - Biology corporation appoints Ulrich M. Grau, PhD, to board of directors

Personnel - Biomaterials maker announces board changes

Personnel - Biopharma company appoints chairman of CNBC to board

Personnel - Biopharma company names chief financial officer

Personnel - Biopharmaceutical company appoints Patrick Murphy as VP

Personnel - Biopharmaceutical company appoints vice president, chief medical officer

Personnel - Bioscience company names vice president of worldwide human resources

Personnel - Biotech company appoints new VP, clinical development and regulatory affairs

Personnel - Cell therapy company adds members to scientific advisory board

Personnel - Chronic rhinosinusitis therapeutics company elects board member

Personnel - Distributor appoints James P. Breslawski president and COO

Personnel - Dr. David Mantus named head of regulatory affairs

Personnel - Dr. H. Bryan Brewer appointed vice chairman, named chief scientific director

Personnel - Dr. Lawrence Olanoff joins company from post at Forest Laboratories

Personnel - Drug and medical device acquisitions company appoints chief medical officer

Personnel - Drug delivery company hires new CEO

Personnel - Drug discovery firm announces key appointments

Personnel - Elie Farah appointec chief financial officer by biopharmaceutical company

Personnel - Estracure appoints member to board

Personnel - Gerard Kennealey named senior VP, chief medical officer of cancer-focused firm

Personnel - Ivan Gergel, MD, named SVP, scientific affairs, president of research institute

Personnel - Life sciences industry veterans join dermatology-focused pharmaceuticals board

Personnel - Members elected to board of directors at pharmaceutical firm

Personnel - Nanotechnology company appoints nonexecutive director

Personnel - Natural plant pharma firm appoints Jeffrey L. Gilbert to its board

Personnel - Pharma company creates center for drug discovery, names director

Personnel - Pharma firm announces key senior additions

Personnel - Pharma firm appoints VP of business development

Personnel - Pharma firm strengthens senior management team with three appointments

Personnel - Pharmaceutical company president, CEO resigns

Personnel - Pharmaceutical firm appoints James E. Fickenscher as chief financial officer

Personnel - Pharmacy benefit manager makes appointment to board of directors

Personnel - Phillip M. Schneider appointed to biotechnology company's board of directors

Personnel - Regenerative medicin-focused company adds 2 to clinical development team

Personnel - Robert C. Salisbury joins board of biopharma company

Pharmaceutical Advertising - Consumer attitudes toward direct-to-consumer advertising examined

Pharmaceutical Research - Another study shows statin drug use reduces the risk of dementia

Pharmaceutical Research - Data about wound healing presented at annual meeting

Pharmaceutical Research - Patients on warfarin have fewer complications with anticoagulation service

Pharmaceutical Research - Report details strategies used by drug companies to win physician support

Pharmaceutical Research - Report examines oncology commercialization spending and staffing

Pharmaceutical Research - Swiss company wins award for cancer drug development

Pharmaceutical Research - Washington University researcher's work licensed to biotechnology company

Pharmaxis - Australian authorities allow Bronchitol for trial patients

Pharmocology - Chymase inhibitors show treatment value in cardiology patients

Philanthropy - Center for Molecular Biotechnology gets grant for trypanosomiasis research

Polycystic Ovary Syndrome - More information needed on combined oral contraceptives for PCOS treatment

Prion Disease - Recent findings in prion disease described

Product Licensing - Company gets worldwide license to Chiron's portfolio of HCV protease inhibitors

Prostate Cancer - AIPC study of calcitriol enhancing Taxotere presented

Prostate Cancer - Acute urinary retention occurred after MRI-guided prostate brachytherapy

Prostate Cancer - Article supporting Ablatherm-HIFU treatment for prostate diseases published

Prostate Cancer - Clinical data on targeted prostate cancer therapy presented at ocology meeting

Prostate Cancer - Data from phase II study evaluating Quadramet with docetaxel reported

Prostate Cancer - Intermittent androgen deprivation treated recurrence after radical prostatectomy

Prostate Cancer - Management of anesthesia during prostate surgery analyzed

Prostate Cancer - New blood test for early detection of prostate cancer introduced

Prostate Cancer - Onyvax-P clinical data presented at conference

Prostate Cancer - Research in prostate cancer provides new insights

Prostate Cancer Vaccine - Updated positive phase 2 data of prostate cancer vaccine presented at meeting

Protein Kinase - Adenylate cyclase examined, nature of potentiation clarified

Protein Kinase C - Amphetamine-stimulated dopamine efflux studied, regulation clarified

Protein Regulation - Aquaporin 1 water channels plot a course for tumor fluid movement

Protein Synthesis - VEGF-activated endothelial cells manufacture corrective proteins

Proteinase - Mast cell secreted proteinases studied, tobacco-mediated overproduction shown

Proteomics - Decorin contributes to insulin-like growth factor signaling

Proteomics - N-cadherin is an upstream modulator of VE-cadherin and vascular morphogenesis

Proteomics - New data illuminates research in proteomics

Proteomics - Nitric oxide cultivates a proangiogenic molecular cascade in endothelial cells

Psoriatic Arthritis - Basal autoantibody levels in biological agent-naive patients determined

Psoriatic Arthritis - FDA approves REMICADE for ninth indication: psoriatic arthritis

Pulmonary Medicine - Assorted factors guide lipofection in murine lung metastasis models

Pulmonary Medicine - Greater cord blood VEGF in preterm infants signals less respiratory distress

Pulmonary Medicine - Interleukin-1 beta examined, effects in adult murine lung defined

Pulmonary Medicine - Lycopene does not improve post-exercise lung function

Quality Assurance - Pennsylvania nurse staffing agency awarded Joint Commission certification

Quality Assurance - Tutogen Medical Earns AATB Accreditation

Rabies - Stochastic special model predicts spatial dynamics for raccoon rabies emergence

Radioprotectors - Amifostine used as radioprotector of salivary glands in radioiodine therapy

Radiotherapy - Hemoglobin levels associated with acute radiotherapy-induced toxicity

Renal Disease - Bone marrow cells buoy glomerular endothelial cell regeneration

Renal Failure - Sirolimus may regress Kaposi sarcoma in renal graft recipients

Renal Function - Renal Na⁺/H⁺ exchange studied, effect of cadmium-intoxication defined

Respiratory Medicine - NAC nebulizing solution with fenoterol or ipratropium characterized

Respiratory Syncytial Virus - 3-Nitrotyrosine protects bronchial epithelial cells from RSV infection

Retinopathy - VEGF receptor 2 blocks murine retinal neovascularization

Retroviruses - TRIM5 alpha proteins block retrovirus infections across primate species

SARS Coronavirus - Anti-SARS-coronavirus activity of cepharanthine determined

Sarcoma - Counting cells in blood samples may predict treatment's effectiveness

Schizophrenia - Hippocampal pathway mediates PCP-induced prefrontal cortex activation

Sexual & Reproductive Health - Cervical cancer vaccine produces high anti-HPV immune response in adolescents

Sexual & Reproductive Health - Study shows mature couples who have sex often have happier relationships

Sexual & Reproductive Health - Survey reveals health misconceptions among women of all ages

Sexual & Reproductive Health - Testis injection site drives electroporation-mediated gene transfer

Signaling Pathways - NF-kappa B examined, peptide-mediated interference of activation revealed

Simian Immunodeficiency Virus - Active SIV CNS infection correlates with neurological disease

Smallpox Vaccines - Research in smallpox vaccines provides new insights

Smooth Muscle - Bronchial receptors studied, role in ACh-mediated RhoA increase revealed

Sociology Research - In U.S., women's weight gain brings loss of income, job prestige, study finds

Spinal Cord Regeneration - Corticospinal regeneration into lumbar gray matter reason for locomotor recovery

Spinocerebellar Ataxia Type 3 - Ataxin-3 inhibits polyglutamine neurodegeneration in Drosophila

Statins - Researchers detail new studies and findings in the area of statins

Stem Cell Research - Activated CB DCs kill tumor cells without damaging normal hematological SCs

Stem Cell Research - Basic FGF supports undifferentiated ESC growth without conditioned medium

Stem Cell Research - Embryonic stem cells extend survival in rats with experimental liver failure

Stem Cell Research - Genetically modified mesenchymal stem cells heal neurological disorders

Stem Cell Research - Intervertebral disc-like cells induced from adult mesenchymal stem cells

Stem Cell Research - Nestin-positive mesenchymal SCs differentiate into excitable neuron-like cells

Stem Cell Research - Notch has role in regulating exocrine progenitor pool

Stem Cell Research - Pit-1 induces hepatic SC differentiation into prolactin-producing cells

Stem Cell Research - Scientists join to develop laboratory model of immune system

Stem Cell Research - Three type of ionic currents identified in mesenchymal stem cells from BM

Stem Cell Research - Transplanted B-stem cells reconstitute bone marrow B-cells after irradiation

Stem Cell Research - Valproic acid stimulates proliferation/self-renewal of hematopoietic stem cells

Stem Cell Transplantation - Embryonic stem cells may be future therapy for inner ear diseases

Stem Cell Transplantation - Fc gamma RIIa-polymorphic site potential target for acute GVHD in allogeneic SCT

Stem Cell Transplantation - Higher CD34 cell dose can reduce pulmonary mortality after TBI-based regimens

Stem Cell Transplantation - New data illuminates research in stem cell transplantation

Stem Cell Transplantation - Race associated with survival after ASCT from IIIA-matched unrelated donors

Stem Cell Transplantation - Thymic recovery onset/thymic output plateau differentially regulated after SCT

Stomach Cancer - New therapy potentially more convenient and better tolerated

Stress Urinary Incontinence - Muscle-derived stem cell culture doesn't need to be pure for SUI treatment

Stroke - NOX4 levels intensify during the revascularization of ischemic brain tissue

Stroke - The impact of treadmill training after cerebral infarction is age-related

Stroke Therapy - Mecobalamin effective for post-stroke carpal tunnel syndrome

Surgical Technology - OmniGuide BeamPath CO2 Mark I Laser Beam Delivery System receives 501K clearance

Testicular Cancer - Testicular cancer gene in mice may offer clues to origins of cancer in men

Thyroid Cancer - AEE788 covers dual targets in anaplastic thyroid carcinoma

Thyroid Cancer - The RET proto-oncogene can be targeted for cancer destruction

Tissue Engineering - 3D femtosecond laser patterning of collagen used for directed cell attachment

Tissue Engineering - Bioactive glasses able to modulate macrophages and monocytes

Tissue Engineering - Chitin-based tubes used for tissue engineering in nervous system

Tissue Engineering - Endothelial cells proliferate on adhesive protein-free synthetic polymer gels

Tissue Engineering - Endothelium directly cocultured on smooth muscle cells

Tissue Engineering - MSCs engineered for total ankle joint repairs for osteoarthritis

Tissue Engineering - Minimal porous PPF scaffold degradation occurs following implantation

Tissue Engineering - Nanoporous alumina membranes improve osteoblast adhesion and proliferation

Tissue Engineering - Reports advance knowledge in tissue engineering research

Tobacco Use - Bupropion SR effective for smoking cessation in health care professionals

Tobacco Use - Health plan provider helps Minnesotans with smoking cessation

Toxins - Site 3 and 4 toxins studied, differential phospholipid binding described

Transfusion Medicine - Deferiprone shows potential for first-line iron chelating drug

Transplant Medicine - Backtransplantation possibilities are documented

Transplant Medicine - Campath 1H induction reduces acute rejection after liver transplantation

Transplant Medicine - Certican approved by Swissmedic to reduce risk of organ rejection

Transplant Medicine - Donor livers from octogenarians thrive after transplantation

Transplant Medicine - Early corticosteroid cessation studied in renal transplant recipients

Transplant Medicine - HLA-A, DGF increases risk for rejection in kidney-pancreas transplant recipients

Transplant Medicine - Hepatitis C virus core protein potentiates cyclosporine immunosuppression

Transplant Medicine - High-immunologic-risk patients may be able to undergo early steroid withdrawal

Transplant Medicine - One man's junk is not another man's treasure

Transplant Medicine - Researchers get grant to study long-term implications of being donating kidney

Transplant Medicine - Sirolimus added to cyclosporine helps with steroid withdrawal

Transplant Medicine - Studies add new findings to transplant medicine body of knowledge

Transplant Medicine - Synthetic myriocin analogue FTY720 deters tumor growth and angiogenesis

Transplant Medicine - T-cell costimulatory molecule promotes long-term survival in skin allografts

Transplant Medicine - Tacrolimus is recommended for kidney transplants when renal function diminishes

Transplant Medicine - VEGFR augments organ survival following transplantation

Tuberculosis - Ipr1 gene mediates innate immunity to tuberculosis

Tuberculosis - Multiple factors influence inability to control tuberculosis in China

Tuberculosis - PI3P retention different in phagosomes containing live or dead mycobacteria

Tuberculosis - Tuberculosis decline in Netherlands over the past decade result of cohort effect

Tuberculosis Drug Development - Quinoxaline-2-carboxylate 1,4-dioxide derivatives have anti-MTB activity

Type 2 Diabetes Therapy - Metformin should be continued with insulin in diabetic patients

Type 2 Diabetes Therapy - Proactive management of diabetes by pharmacists benefits patients

Ulcerative Colitis - Alternative prevents UC-associated colon cancer

Ulcerative Colitis - Higher dose of mesalamine more effective in moderately active ulcerative colitis

Umbilical Cord Blood Banking - Umbilical cord blood banking promises families biological "insurance"

Umbilical Cord Blood Transplantation - Modified cord blood collection method achieves sufficient cell levels for CBT

Urinary Incontinence - Company launches urinary incontinence treatment, updates finances

Vaccine Development - Biopharma company begins studies of vaccine to produce antistaph antibodies

Vaccine Development - Proteomic profiling of E. coli fermentation improved protein production

Vaccine Development - U.S. FDA grants special protocol assessment for trial of GVAX vaccine

Vanilloid Receptors - TRPV channel subunits analyzed, homo- and heteromeric assembly revealed

Vector Development - Leaky tumor vessels allow systemic gene transfer after adenoviral transfection

Vector Development - Researchers detail new studies and findings in the area of vector development

Virology - Hepatitis C NS5A quasispecies dynamics impact the value of combination therapy

Virology - Recent studies add new data to virology research

Virology - Reporter replicons establish a way to analyze hepatitis E virus biology

Virology - Tupaia liver cells model interactions with hepatitis C

Warts - Dermatologists use immunotherapy to treat warts

Wound Care - U.S. FDA grants clearance for absorbant antimicrobial barrier dressing

Wound Healing - Adenosine A_2A receptor boosts angiogenesis by blocking thrombospondin 1

Xerostomia - Saliva substitutes treated xerostomia following radiotherapy

Yersinia Pestis - Y. pestis CRISPR elements acquire new repeats by bacteriophage DNA uptake

Zollinger-Ellison Syndrome - Follow-up study of Zollinger-Ellison syndrome patients from 1966-2002 conducted

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