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Acute Myeloid Leukemia
New findings in acute myeloid leukemia described
June 17th, 2005
Data on acute myeloid leukemia are outlined in reports from Taiwan, the United States and Germany. Study 1: CEBP alpha gene mutations occur in 6% of childhood acute myeloid leukemia. According to published research from Taiwan, "CEBPalpha mutations have been described in adult acute myeloid leukemia (AML) and conferred a favorable prognosis. However, CEBPa mutation has not been reported in children. We investigated 117 children with de novo AML using DNA PCR assay followed by sequencing for each PCR product." "CEBPa mutations were detected in 7 patients, 4 had FAB M2, two M1 and one M4. CEBPalpha mutations only occurred in...
Source: Drug Week (2005-06-17)
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