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Drug Week

Susan Hasty, Publisher

Table of Contents . . . July 8th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Anemia - Exploratory analysis of CERA data shows sustained and stable control of anemia

Cardiovascular Therapy - Valsartan/HCTZ combination is good for patients with added CV risk

Drug Development - Hematide clinical results demonstrate potent effect on red blood cell production

Drug Development - U.S. FDA grants tentative approval of Zolpidem ODT for sleep disorders

Rosacea - Oracea demonstrated up to a 61% reduction in inflammatory lesions in trial

Acetaminophen - Fever control in septic shock examined, benefit or harm probed

Acinetobacter Baumannii Outbreaks - 3rd-gen. cephalosporin therapy risk for VEB-1 ESBL A. baumannii outbreak

Acne - Trial of medical device for pimples information reported

Acute Lung Injury - COX-2-derived products play key roles in resolution

Acute Myeloid Leukemia - Results of clofarabine trial in adult AML presented at conference

Addiction Medicine - Buspirone shows promise for treatment of opioid withdrawal

Angiology - Researchers provide details of new studies and findings in the area of angiology

Addiction Medicine - Hythiam invited to join NADCP as a Pioneer Member

Addiction Medicine - MELD scores are superior predictors of alcoholic hepatitis related mortality

Addiction Medicine - Neuropeptide Y polymorphism associates with alcohol dependence

Addiction Medicine - New findings in the area of addiction medicine described

Adenocarcinomas - Modulated fluorouracil regimen treated adenocarcinoma of the large bowel

Adrenoceptors - Neocortical and visuo-spatial activities studied, effect of malnutrition shown

Cancer Therapy - Research in cancer therapy provides new insights

Adverse Drug Reaction - Patients with interferon-induced Graves disease fare better than others

African Trypanosomiasis - Ten-day melarsoprol regimen effective for late-stage HAT

Age-Related Macular Degeneration - Target enrollment reached in EVIZON phase II trial (MSI-1256F-209) in AMD

Aging - Aging linked to decreased muscle mass and increased fat

Aging - Senile seminal vesicle amyloid analyzed, semenogelin derivation revealed

Aicardi-Goutieres Syndrome - Study of Aicardi-Goutieres may yield better understanding of CNS calcification

Diabetes Therapy - New findings in the area of diabetes therapy described

Alcoholism - Chinese kudzu extract may be useful as treatment adjunct

Allergic Rhinitis - Allergen promotes class switching to IgE in nasal mucosa

Allergy Medicine - Anti-allergen IgE antibodies studied, quantitative measurement reported

Allergy Medicine - Atopic asthma examined, increase in killer-specific secretory protein shown

Allergy Medicine - Fungal fragments and conidia studied, role as aeroallergens revealed

Allergy Medicine - Researchers engineer hybrid molecule resembling the spectrum of grass pollen

Diabetes Therapy - Recent findings illuminate research in diabetes therapy

Allergy and Immunology - CD28 signals stabilize epigenetic modifications of interleukin-2 promoter

Allergy and Immunology - Company introduces chemistry technology for oligonucleotide-based therapeutics

Allergy and Immunology - Steroid receptor function sways glucocorticoid-mediated immunosuppression

Alzheimer Disease - Antibody treatment might show reversible cognitive deficits

Alzheimer Disease - Bioscience company describe new in-cell western assay in published paper

Alzheimer Disease - Company files new drug application for compound to treat Alzheimer disease

Diabetes Therapy - Research in diabetes therapy provides new insights

Alzheimer Disease - Nerve growth factor gene therapy looks promising

Amyloid A Amyloidosis - Fibrillex study data for Amyloid A Amyloidosis presented at conference

Anal Cancer - Therapeutic options and pattern of local failure after radiotherapy reported

Analgesia - Analgesic usage for low back pain impacted health care costs and service use

Anemia - Continuous erythropoietin receptor activator for anemia study results reported

Anesthesia - Transmucosal lidocaine patches effective for scaling and root planing

Diabetes Therapy - Researchers' data advance diabetes therapy research

Angiology - 17beta-estradiol studied in aorta contraction

Angiology - Enriched genes aid aortic adaptation to biomechanical stress

Angiology - Reports add new data to angiology research

Angiology - Shear stress helps embryonic stem cells become vascular endothelial cells

Animal Models - Humanized ABCA1 murine model developed

Diabetes Therapy - Researchers' work adds to diabetes therapy body of knowledge

Ankle Sprains - Study compares acetaminophen to ibuprofen in treatment of ankle sprains

Anthrax - Inhibitors of quorum-sensing have potential in anthrax therapy

Anti-infectives - Genotoxicity of 2-furylethylenes and 5-nitrofurans evaluated

Antibiotic Resistance - Microarray detects antimicrobial resistance genes in Gram-positive bacteria

Antidepressants - Hyperforin activates nonselective cation channels (NSCCs)

Antidpressant Drugs - Trazodone and its active metabolite, m-CPP, assessed

Diabetes Therapy - Studies add new findings to diabetes therapy body of knowledge

Antimicrobial Resistance - Class 1 integrons characterized in South Korean E. coli

Antimicrobials - Antimicrobial peptide rCRAMP studied, central nervous system location revealed

Antioxidants - Gingival fibroblasts studied, role of nicotine in heme oxygenase shown

Antioxidants - Interaction between M. truncatula and S. meliloti reported

Antipsychotic Therapy - Direct transition to long-acting injectable risperidone safe and effective

Antiviral Therapy - Combination therapy produces a sustained response in HCV cirrhosis

Diabetes Therapy - Studies advance knowledge in diabetes therapy research

Apoptosis - Mesangial cell apoptosis analyzed, signaling and apoptotic events clarified

Apoptosis - T lymphocyte arrest and apoptosis analyzed, influences of burn injury clarified

Artherosclerosis - Weight gain during intensive therapy put diabetics at risk for atherosclerosis

Arthritis - Etanercept treated patients with systemic onset juvenile rheumatoid arthritis

Arthritis - Ginkgo terpene has anti-inflammatory effect on C. albicans-related arthritis

Arthritis - Hyaluronan affected inflammatory cytokines in knee osteoarthritis

Diabetic Nephropathy - Reports describe recent advances in diabetic nephropathy research

Arthritis - New drug helps improve mobility in children with arthritis

Arthritis - Researchers look into mesenchymal stem cell immunosuppressive properties

Arthritis - Study shows RA drug is safe and well-tolerated

Atherosclerosis - Basal NO activity is preserved in patients with moderate coronary disease

Attention Deficit Hyperactivity Disorder - Pharma company launches scholarship for ADHD adults

Autism - First patient enrolled in trial for GI dysfunction in autistic children

Diagnostics - Researchers publish new studies and findings in the area of diagnostics

Autoimmune Disease - CIITA polymorphism may be related to systemic lupus erythematosus pathogenesis

Avian Influenza - Biomanufacturing company reports progress of avian transgenics project

Avian Influenza Outbreak - Nonhomologous recombination between HA/matrix genes caused HPAI emergence

Awards - Gates Foundation awards $21.8 million grant to advance anti-hookworm vaccine

Bacterial Conjunctivitis - Over-the-counter antibiotic for acute bacterial conjunctivitis launched

Basal Cell Carcinoma - Company doses first patient in phase I clinical trial for basal cell carcinoma

Enzymology - Researchers provide details of new studies and findings in the area of enzymology

Benign Prostatic Hyperplasia - Pharma company reports positive new data for benign prostatic hyperplasia drug

Bioengineering - Gene knockout targets elicit lycopene synthesis in Escherichia coli

Biomedical Engineering - Self-assembling genetically engineered hydrogels have biomedical potential

Biosynthetics - Prostaglandin biosynthetic pathway markers augment lung cancer angiogenesis

Biotechnology - Neuroscience-based biotech announces the appointment of new board directors

Bioterrorism - Positive interim results reported from phase I clinical trial of RiVax

Immunology - Reports advance knowledge in immunology research

Bipolar Disorder - Therapeutic potential of cannibinoids evaluated

Blood Cancer - Trial of second-generation Hsp90 inhibitor in hematologic cancers initiated

Bloodstream Infection - Outbreaks from contaminated water for injection

Bone Marrow - Chimerism and clinical outcomes of donor bone marrow transplants reported

Bone Tissue Engineering - Crystalline octacalcium phosphate coating suitable for bone tissue engineering

Brain Cancer - DNA-dependent protein kinase blockade triggers autophagy in irradiated cells

Leukemia - Researchers publish new studies and findings in the area of leukemia

Brain Cancer - Endoglin is a better marker of glioblastoma angiogenesis than CD31

Brain Metastases - Guidelines on optimal radiotherapeutic management of brain metastases shared

Breast Cancer - DNA vaccination/BAT combo protects against incipient carcinomas

Breast Cancer - Researchers describe findings in breast cancer studies

Breast Cancer - Side effects reduce low-income Latinas' inclination to join clinical trials

Breast Cancer - Study of 4-hydroxytamoxifen gel published in Journal of Clinical Oncology

Obstetrics - Studies add new findings to obstetrics body of knowledge

Business & Finance - Biosciences corporation announces second quarter financial results

Business & Finance - Company focused on neuropsychiatric disorders announces $65 million financing

Business & Finance - Consumer products company announces financial results

Business & Finance - GlaxoSmithKline makes milestone payment, begins thrombocytopenia drug trial

Business & Finance - Radiation therapy products company announces financial results

Business Update - Agreement inked with Introgen Therapeutics for manufacturing services

Oncology - Recent findings in oncology described

Business Update - Cancer-focused pharmaceutical company enters distribution business

Business Update - Cardiovascular device-focused company featured in European medical publication

Business Update - Company announces agreement to promote Alcortin and Novacort to dermatologists

Business Update - Company delivers dual-targeting drug candidate to Abbott

Business Update - Company launches Genuine Cultures emblem

Business Update - Company updates development status of ONO-2506 for Injection/PROGLIA

Oncology - Recent findings in oncology provide new insights

Business Update - Daiichi continues BioExpress System subscription

Business Update - Distribution of Sucanon expanded in Mexico

Business Update - Drug discovery company expands research capabilities in Asia-Pacific region

Business Update - Drug-development company expands capacity

Business Update - Health services company amends agreement with Peking Union Medical

Business Update - Hemosol Announces Share Consolidation

Oncology - Research in oncology provides new insights

Business Update - Hitachi Software to distribute Phenyx MS software platform

Business Update - Information solutions company completes sale of German operations

Business Update - Inhibiton Therapeutics announces stock symbol Change to "IHBT" immediately

Business Update - Intraop Medical Mobetron selected for University of Verona IORT program

Business Update - Introgen Therapeutics pursues dual listing on London Stock Exchange

Business Update - Launch of e-Proxemis announced

Oncology - Researchers detail new studies and findings in the area of oncology

Business Update - Manufacturer receives equipment orders from Indonesia, India, and China

Business Update - Matrix enters development and commercialization agreement

Business Update - Medical communications network announces new ownership

Business Update - Pharma company manufacturing company receives approval for tablets unit

Business Update - Pharma company research and development facility receives GLP certification

Business Update - Robert V. LaPenta forms new biometrics investment firm

Oncology - Researchers provide details of new studies and findings in the area of oncology

Business Update - Vaccine maker announces relocation of headquarters to the U.S.

Caffeine - Cognitive and mood effects compared in habitual users and non-users

Cancer Immunotherapy - Antigen-encoded viruses offer protection against prostate cancer

Cancer Immunotherapy - Reengineered dendritic cells need natural killer cells for melanoma targeting

Cancer Research - No objection letter received from U.K. for Tectin clinical trial

Cancer Research - Research on apoptosis in cancer cell discussed

Proteomics - Researchers report details of new studies and findings in the area of proteomics

Cancer Therapy - Antitumor antibodies maintain therapeutic levels after gene transfer

Cancer Therapy - Biopharmaceutical company publishes article on activation of apoptosis

Cancer Therapy - Clofarabine active in a broad range of hematologic cancers

Cancer Therapy - Data reveals a promising new approach in cancer

Cancer Therapy - Endostatin gene therapy and gemcitabine join forces to battle lung cancer

Cancer Therapy - FavId phase II clinical trial begins in Europe

Proteomics - Studies advance knowledge in proteomics research

Cancer Therapy - Findings in cancer therapy provide new insights

Cancer Therapy - General population and cancer patient norms assessed

Cancer Therapy - New regulators of apoptosis and chemoresistance identified

Cancer Therapy - Oncophage cancer vaccine gets European orphan drug designation

Cancer Therapy - Research aims to match tumors with the most effective treatments

SARS Coronavirus - New findings in SARS coronavirus described

Cancer Therapy - SJ-8026 amplifies tumor apoptosis and halts angiogenesis

Cancer Therapy - Tyrosine kinase inhibitor AZD2171 subdues tumor angiogenesis

Carcinogenesis - Vitamin K-2 and perindopril combine to attenuate preneoplastic liver lesions

Cardiac Pacemakers - Most popular lead glucocorticosteroids have comparable performances

Cardiology - ARBs reduce left ventricular remodeling and improve function and survival

Cardiology - Divergent gene profiles underscore hypertrophy and heart failure

SARS Coronavirus - New findings in the area of SARS coronavirus described

Cardiology - Enrollment in study of TNKase/ Metalyse used prior to angioplasty suspended

Cardiology - Observations identify fundamental characteristics of coronary circulation

Cardiology - Omega-3 fatty acids exhibit direct electrophysiological effects

Cardiology - Researchers provide details of new studies and findings in the area of cardiology

Cardiology - Small study shows advanced heart failure patients improve with stem cell therapy

Cardiology - Successful preclinical trials in congestive heart failure reported

Vector Development - Researchers publish new studies and findings in the area of vector development

Cardiomyocytes - A3 R agonist delayed dissipation in mitochondrial membrane during hypoxia

Cardiomyopathy - Study examined mechanism for reduced long-axis lengthening velocity

Cardiomyopathy - Study examined stiffness and contracting myocytes in infarct thickening

Cardiovascular Disease - Higher plasma lycopene concentrations were not associated with CV risk

Cardiovascular Disease - Mineralocorticoid receptor antagonists may have potential in CV disease therapy

Cardiovascular Disease - Reports add new data to cardiovascular disease research

Virology - Researchers report details of new studies and findings in the area of virology

Cardiovascular Disease - Study examined Vitamin D contribution to CV disease patients with kidney disease

Cardiovascular Research - Angiogenesis is a multifaceted controller of ectopic calcification

Cardiovascular Research - Corticosteroids reprogram genes to fight doxorubicin-related death

Cardiovascular Research - Study supports clinical use of PFA-100 to measure aspirin resistance

Carotid Artery Stenosis - Determinants of carotid endarterectomy anatomic durability identified

Carotid Endarterectomy - Local argatroban application may prevent embolic complications

Catheter Infection - Intravenous iron not associated with acute microbial growth in catheters

Cell Biology - Coupling prototypes predict VEGF isoform behavior in human pathology

Cellular Therapy - Trials initiated for autologous cellular therapies for tissue regeneration

Central Precocious Puberty - Environmental factors may induce central precocious puberty in NW Tuscany

Chemotherapy - ABCC2 drug transporter gene mutation impairs methotrexate elimination

Chemotherapy - Adjuvant chemotherapy employed in completely resected non-small-cell lung cancer

Chemotherapy - Antiemetic prophylaxis used during chemotherapy of gastrointestinal tumors

Chemotherapy - Cisplatin and gemcitabine induction chemotherapy used in advanced NSCLC

Cholera Epidemics - Host-mediated phage amplification self-limits cholera epidemics

Chronic Heart Failure - Allopurinol had no effect on exercise capacity of CHF patients

Chronic Hepatitis C - Amantadine does not improve the value of hepatitis C combination therapy

Cirrhosis - Branched-chain amino acids beneficial to glucose metabolism in cirrhosis

Clinical Trials - IDM granted "cell therapy establishment" designation

Clinical Trials - Impact of study criteria on generalizability of results clarified

Clinical Trials - Report: Attracting top clinical investigators means building relationships

Clinical Trials - U.K. Health Authority approves launch of phase I clinical trials for CH-1504

Collaborations - Agreement signed for distribution of Suplasyn

Collaborations - Agreement signed to manufacture AS1410 for clinical trials

Collaborations - Alliance to deliver proteomic solutions for biomarker discovery, validation

Collaborations - Ambion granted license to fundamental RNAi patents

Collaborations - Breast cancer detection clinic enters alliance with pharma company

Collaborations - Collaboration announces breakthrough in avian transgenic biomanufacturing

Collaborations - Collaboration to focus on therapeutics for cancer, inflammation, tissue repair

Collaborations - Deal entered with Ortho-McNeil to develop compounds for asthma, allergies

Collaborations - Deal signed to develop, commercialize a therapeutic monoclonal antibody

Collaborations - Deal signed with Intradigm to develop topical drugs for ophthalmic uses

Collaborations - Diagnostic biomarker collaboration with Ortho-Clinical Diagnostics launched

Collaborations - Feasibility studies initiated for intranasal drug delivery in type 2 diabetes

Collaborations - Licensing agreement signed for antibody phage display patent estate

Collaborations - Paclitaxel franchise broadened with license to Broncus Technologies

Collaborations - Pharma companies partner to develop preclinical compounds

Collaborations - Research solution company and Elsevier partner to offer bioscience database

Collaborations - Therapeutics companies establish alliance to develop monoclonal antibodies

Colon Cancer - IGF-I binding protein gene variants boost colorectal cancer vulnerability

Colorectal Cancer - Co-morbidity leads to worse survival of elderly patients with colorectal cancer

Community-Acquired Pneumonia - Data analysis completed for community-acquired pneumonia trial

Complementary and Alternative Medicine -  Oenanthe javanica flavone is a potent hepatitis B virus inhibitor

Complementary and Alternative Medicine - Prayer is an effective alternative therapy

Congestive Heart Failure - Heart failure patients perceive improvement on Candesartan treatment

Congestive Heart Failure - Study demonstrates outcomes of patients implanted with HeartMate XVE

Contact Lens - Conservative treatment option for extreme corneal ectasias and severe dry eye

Contraception - NuvaRing active ingredients don't interact with antibiotics

Coronary Arteries - Study investigated effect of folic acid on coronary dilator function

Coronary Artery Bypass Surgery - Study examined effects of ceasing aspirin before bypass surgery

Coronary Artery Disease - Adenosine has mitogenic effects in porcine coronary artery cells

Coronary Artery Stent - Excess drug-eluting stent length causes slight rise in restenois risk

Cotransporters - Intestinal Ca2+ uptake examined, influence of NaCl-cotransporter clarified

Dementia - New memory drug works best in combination with older remedy

Dental Fluorosis - Study shows fluoride damages children's bones

Depression - Tetanus toxin found to have therapeutic properties

Depression Therapy - 5HTTLPR genotype affects SSRI efficacy

Depression Therapy - Chronic citalopram treatment normalizes 5-HT synthesis in OBX rats

Depression Therapy - Effect of citalopram on circulating adenosine and serotonin determined

Dermatology - Adults and children use hydrocortisone creams in safe amounts

Dermatology - Autologous vaccine powers immunological response to melanoma

Diabetes Diagnosis - Diabetes center publish fourteenth edition of research and treatment textbook

Diabetes Pathogenesis - Glucagon-like peptide-1 linked to metabolic abnormalities

Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights

Diabetes Pathology - ENT-1 affects adenosine availability which alters vascular function in diabetes

Diabetes Risk Factors - Kidney recipients with hepatitis C are at risk for developing diabetes

Diabetes Therapy - Data demonstrates greater flexibility with mealtime dosing of Apidra

Diabetes Therapy - New data illuminates research in diabetes therapy

Diabetes Treatment - Adenovirus expressing O-GlcNAcase improves contractile function of heart

Diabetes Treatment - Enzyme gemfibrozil elevates plasma concentration of pioglitazone

Diabetes Treatment - Researchers note unique antioxidative effect of fluvastatin in diabetics

Diabetic Distal Symmetrical Sensory Polyneuropathy - High-frequency external muscle stimulation is an effective therapy for DSP

Diabetic Nephropathy - Recent findings in diabetic nephropathy described

Diabetic Neuropathy - Findings in diabetic neuropathy provide new insights

Diagnostic Imaging - Functional and anatomic imaging quantifies gene transfer in murine tumors

Diagnostics - Bacterial identification, antibiotic susceptibility testing system launched

Diagnostics - Biosensor system characterizes epidemic in military training camp

Diagnostics - Collaboration to evaluate the performance of certain gene methylation markers

Diagnostics - Company launches Deep Proteome Research Services

Diagnostics - IgM anti-hepatitis C virus titers divulge the threat of acute hepatitis

Diagnostics - Immunetrics Inc. Secures Biomarker Collaboration

Diagnostics - Magnetic resonance spectroscopy compared to perfusion-weighted imaging

Diagnostics - Real-time testing distinguishes SYT-SSX rearrangements in synovial sarcomas

Diagnostics - Reports add new data to diagnostics research

Diagnostics - Study confirms NT-proBNP is useful as predictor of mortality in HF patients

Diet & Nutrition - Study: Almonds reduce inflammation

Diffuse Brain Injury - Changes in metabotropic glutamate receptor expression characterized

Dopamine Receptors - Dense core vesicle release studied, protein-receptor regulatory role revealed

Drug Abuse - Public in favor of controlling OTC products used to make methamphetamine

Drug Activity - Linezolid versus vancomycin activity studied in pharmacodynamic model

Drug Delivery - Coatings for oral calcitonin carriers compared

Drug Delivery - Company announces publication of Oral-lyn research study

Drug Delivery - Ktenate nanoparticles used to deliver drugs to parasites and tumors

Drug Delivery - Nanoparticles carry cancer-killing drugs into tumor cells

Drug Delivery - Researchers' work adds to drug delivery body of knowledge

Drug Delivery - Tumor cells take up tailor-made self-assembled polyelectrolyte shells

Drug Development - Agreement signed for manufacture of 24-hour CDT pseudoephedrine tablets

Drug Development - Aloxi launched in U.K. for chemotherapy induced nausea and vomiting

Drug Development - Antioxidant therapy launched by Colorado company

Drug Development - Colorimetric assay facilitates identification of antileishmania drugs

Drug Development - Company recognized for development of sarcoma treatment

Drug Development - Data presented on phase II study of pramlintide

Drug Development - Hemosol announces completion of Health Canada inspection

Drug Development - Imvamune protects monkeys against smallpox-like virus

Drug Development - Inhibitex to present at the BIO 2005 Annual International Conference

Drug Development - Institute for OneWorld Health to exhibit at BIO convention

Drug Development - Introgen continues to advance INGN 007 for the treatment of cancer

Drug Development - Investigational anthrax antibody effective in recognized animal model

Drug Development - Keflex powder for oral suspension launched in the United States

Drug Development - Pharmaceutical company launches out-licensing program for novel formulations

Drug Development - Phase I study of growth hormone completed

Drug Development - Positive phase I trial results reported for Indaflex

Drug Development - Positive results reported with Neugene antisense drugs

Drug Development - Scientists look for drugs from the deep blue

Drug Development - Takeda extends BioExpress System Subscription

Drug Development - Trial for oral PDE-5 inhibitor for treating cardiovascular diseases begun

Drug Development - U.S. FDA grants approval for extended-release Glumetza

Drug Research - Canstatin uses integrin crosstalk to cancel tumor growth

Drug Resistance - Multidrug resistance protein analyzed, functional interactions clarified

Drug Safety - Pharmaceutical company announces recall of children's medication

Dry Eye Syndrome - Pharmaceutical company announces dry eye syndrome clinical trial fully enrolled

Electrochemistry - Electrochemical characterization of the human cytochrome P450CYP2C9

Embolisms - Bed rest linked to pulmonary embolism in patients with deep vein thrombosis

Endocrinology - Findings in endocrinology provide new insights

Endocrinology - Gene therapies slay thyroid cancer cells in patients with end-stage disease

Endocrinology - Insulin-like growth factor deficiency retards intrauterine and postnatal growth

Endocrinology - Interactions of Pax8 and TTF-1 inaugurate thyroid specific gene expression

Endocrinology - Pancreatic islet-specific transgenes counter growth hormone shortage

Endocrinology - Pharmacokinetic, safety data from studies presented at Endocrine Society meeting

Endocrinology - UCLA study shows dosing regimen of hormone improves short stature in children

Endogenous Retrovirus - HERV rec interferes with germ cell development and may cause carcinoma

Enzymology - Heat shock protein helps gene-directed enzyme prodrug therapy manage tumors

Enzymology - Researchers detail new studies and findings in the area of enzymology

Ephedrine - Ephedrine detection examined, receptor-based optical spot test developed

Epidemiology - Rate of new HIV infections increasing in Saudi Arabia

Epilepsy - Delaying medication for infrequent seizures may be the best option

Epilepsy - Topiramate pharmacokinetics studied in children and adults with epilepsy

Epstein-Barr Virus - Reports add new data to epstein-barr virus research

Epstein-Barr Virus-Related Lymphoma - HMG CoA reductase inhibitors delay development of EBV-driven lymphoma

Erectile Dysfunction - NT3 gene therapy applicable for treatment of diabetes-induced ED

Erythropoiesis - Patient exclusion criteria correlated to efficacy of ESAs in anemic patients

Esophageal Cancer - Advances in Barrett's esophagus and esophageal adenocarcinoma shared

Expression Vectors -  Escherichia coli manufactures recombinant human endostatin

Finance - Biopharmaceutical company shareholders approve proxy proposals at meeting

Finance - Biopharmaceuticals company announces private placement financing

Finance - Biopharmaceuticals firm secures $2.5M financing

Finance - Biotech company forecasts 5% decline in sales

Finance - Biotech company secures $20M capital injection for further product development

Finance - Company focused on diseases of oxidative stress discusses financials

Finance - Drug development company announces financial results

Finance - Immunomedics' chairman provides intrafamily stock transfer details

Finance - Inflammatory disease-focused pharmaceutical company reports $5 million placement

Finance - Medical device maker announces $750,000 private placement

Finance - Nuclear transfer technology firm reports files Form 10-QSB with U.S. SEC

Finance - Peptide developer announces final results of warrant exchange

Finance - Pharma firm announces post-reverse stock split trading

Finance - Pharmaceutical company expects to deliver EBITDA margin above 26%

Finance - Pharmaceutical firm announces $3.3M closing of stock sale

Finance - Pharmaceuticals firm announces developments relating to credit facility

Finance - Pharmaceuticals firm reports slight decrease in revenues

Finance - SBIR grant awarded for enhancements to core information management system

Finance - Sucanan maker subscribes for $250,000 private placement

Financing - Adult stem cell therapy company finalizes investment round

Fitness and Wellness - Studies presented at conference focus on nutrition and exercise

Food-Borne Illness - Food safety knowledge gaps in relief workers can lead to disease outbreaks

Foot and Ankle Surgery - ChloraPrep highly effective for presurgical pathogen removal

Gastric Cancer - Loss of Ep-CAM (CO17-1A) expression predicts survival gastric cancer patients

Gastric Cancer - ROS stimulates cell invasiveness of human gastric cancer AGS cells

Gastroenterology - Aspirin use and risk of biliary tract cancer studied in Shanghai, China

Gastroenterology - Endoscopic mucosal resection is contraindicated for submucosal gastric cancer

Gastroenterology - Time-dependent inactivation of CYP3A in cryopreserved human hepatocytes studied

Gene Research - Data from meeting of the American Society of Gene Therapy highlighted

Gene Research - Genetic testing products company to supply Emory Genetics Lab with reagents

Gene Research - Liver gene profiles signal patient response to hepatitis C therapy

Gene Research - Mcl-1 diminishes proteasome inhibitor-induced apoptosis

Gene Research - Nuclear receptor interaction protein augments cancer cell transcription

Gene Silencing - Research add new data to gene silencing body of knowledge

Gene Therapy - Company reports on DNA drug delivery for brain and eye diseases

Gene Transfer - Fractalkine gene therapy relies on immune system support for tumor killing

Gene Transfer - Researchers' data advance gene transfer research

Generic Drugs - IVAX begins sale of generic OxyContin as authorized distributor

Generic Drugs - Study shows pharma company plan to extend generics lines

Genetics & Genomics - DNA-focused pharma to provide pharmacogenetic support to INC Research

Genetics & Genomics - Genetic switch for maturation discovered

Grants - Marie Curie fellowship grant for $1.1 million awarded by European Union

Grants - Winners of Shock Society research grant for hemorrhagic shock, hemostasis named

Gynecology - Circulating VEGF correlates with ovarian cancer progression in study models

Gynecology - TVS doesn't aid diagnosis of endometrial pathology in women taking tamoxifen

HIV/AIDS Diagnostics - Data presented on ultra-deep sequencing of HIV virus

HIV/AIDS Diagnostics - Direct volumetric measurements correlate with flow cytometry for CD4 measurement

HIV/AIDS Diagnostics - HIV infection affects uPAR release in whole-blood cultures

HIV/AIDS Drug Development - Caffeine and caffeine-related methylxanthines inhibit HIV-1 replication

HIV/AIDS Drug Development - Glycyrrhizin inhibits R5 HIV replication in 1-methyladenosine-treated PBMCs

HIV/AIDS Drug Development - Small-molecule HIV-1 entry inhibitors target the gp120-binding domain of CD4

HIV/AIDS Epidemiology - More undiagnosed HIV infections in fall/winter than summer in hospital patients

HIV/AIDS Epidemiology - P1/P1 haplotype linked to elevated HIV CCR5 expression in Chinese population

HIV/AIDS HAART - Long-term antiretroviral NRTI treatment associated with adverse events

HIV/AIDS Needle Exchange - Secondary needle exchange associated with greater likelihood of drug treatment

HIV/AIDS Pathogenesis - Env does not play active role in host HLA-DR acquisition by emerging HIV-1

HIV/AIDS Pathogenesis - HIV-1 primer choice dependent on tRNA structure for nucleocytoplasmic transport

HIV/AIDS Pathogenesis - Nonreplicating HIV-1 contributes to T cell depletion by activating CD4/CD8 cells

HIV/AIDS Pathogenesis - RLI may act as mechanochemical enzyme in ribosome and HIV capsid biogenesis

HIV/AIDS Pathogenesis - SP1 affects HIV-1 Gag-membrane binding and subsequent events of virus assembly

HIV/AIDS Pathogenesis - Studies describe new findings in HIV/AIDS pathogenesis research

HIV/AIDS Prevention - Emergency departments used as public health programs for HIV-risk populations

HIV/AIDS Prevention - HIV/AIDS peer education program in a South African workplace was ineffective

HIV/AIDS Prevention - Men & women improve safe sex habits following HIV/AIDS prevention intervention

HIV/AIDS Prevention - World leaders asked to redouble efforts to develop HIV vaccines, microbicides

HIV/AIDS Prognosis - High plasma suPAR independent predictor of mortality in HIV-1-infected patients

HIV/AIDS Research - CTIP2 represses initial phase of HIV-1 gene transcription in microglial cells

HIV/AIDS Research - GEP inhibits HIV-1 transcription via Tat without directly binding to cyclin T1

HIV/AIDS Research - Mouse model generates HIV specific human humoral and cellular immune response

HIV/AIDS Research - Mutant HIV dimeric RNA has same stability/conformation as wild-type RNA dimers

HIV/AIDS Resistance - HIV CCR5 variant associated with HIV resistance in Chinese population

HIV/AIDS Risk Factors - Risky sex/amyl nitrite/lack of circumcision associated with HIV seroconversion

HIV/AIDS Testing - Companies announce new campaign to encourage Americans to get tested for HIV

HIV/AIDS Therapy - Combination antiretroviral therapy reduces T cell activation in CSF and blood

HIV/AIDS Therapy - Enfuvirtide provides substantial gains in quality-adjusted life expectancy

HIV/AIDS Therapy - Trial evaluates antiretroviral salvage therapy

HIV/AIDS Transmission - Selection during HIV-1 transmission may vary depending on infecting subtype

HIV/AIDS Treatment - Healthcare IT software company plays role in Kenyan AIDS clinic

HIV/AIDS Vaccines - Researchers detail new studies and findings in the area of HIV/AIDS vaccines

HIV/AIDS-Related Depression - Depression associated with diminished quality-of-life among HIV-infected persons

HIV/AIDS-Related Infection -  Mycobacterium simiae cause of peritoneal dialysis peritonitis in HIV patient

HIV/AIDS-Related Lipodystrophy - Lipodystrophy-related symptoms impair quality of life in HIV-infected patients

HIV/AIDS-Related Stevens-Johnson Syndrome - Stevens-Johnson syndrome may be induced by HIV pregnant women taking antibiotics

Head and Neck Cancer - The new Myc-target gene mimitin stimulates esophageal cancer proliferation

Head and Neck Cancer - Tumor-dendritic cell fusion vaccine is valid immunotherapy approach

Health Insurance - Benefits manager reports zero increase in generic prescription drug spending

Healthcare Costs - Fewer prescriptions, lower costs follow Claritin's over-the-counter switch

Healthcare Costs - Hepatitis C therapy lowers long term costs and improves survival rates

Healthcare Costs - Study finds lack of medication compliance leads to high medical costs

Healthcare Costs - Study shows healthcare is Michigan's largest employer

Healthcare Coverage - Health insurance provider introduces health plan for small business

Healthcare Coverage - Healthcare informatics venture announces results of managed care audit

Healthcare Coverage - Prescription drug program success highlighted

Heart Failure - PDE5 inhibition with sildenafil improves cardiac output

Hematological Malignancy - Epithelial cancer antigens increase anticancer cell activity

Hematology - Imatinib and mcl-1 antisense synergize to beat chronic myeloid leukemia

Hematology - Researchers report details of new studies and findings in the area of hematology

Hematology - Sickle cell plasma alters gene expression in endothelial cells

Hemodilution - HV plasma in extreme hemodilution increases perivascular NO concentration

Hepatic Cancer - Benefit of biologic parameters in IMRT optimization assessed

Hepatitis B Immunization - Infant vaccination fights hepatitis B endemicity in Malaysia

Hepatitis B Virus - RNAi therapeutics company publishes hepatitis B virus data in 'Hepatology'

Hepatitis C - Novartis licenses rights to develop and commercialize new hepatitis treatment

Hepatitis C Epidemiology - Hepatitis C genotype changes in Italian children forecast better outcomes

Hepatitis C Therapy - Bayesian therapeutic monitoring predicts ribavirin-induced anemia

Hepatitis C Therapy - Patients with chronic hepatitis C genotype 4 respond to therapy earlier

Hepatitis C Virus - Tolerized rats model human hepatitis C infection

Hepatitis E Virus - Interferon gamma genotypes raise susceptibility to acute hepatitis E

Hepatocellular Cancer - Doppler ultrasonography assessed tumor necrosis after PEI

Hepatocellular Cancer - Efficacy of hepatocellular carcinoma locoregional therapies evaluated

Hepatocellular Carcinoma - Murine liver tumors respond to combined suicide-cytokine gene therapy

Hepatology - Adiponectin may be a cholestasis marker in chronic liver disease

High Cholesterol - Study shows Docosahexaenoic acid lowered triglycerides and bad cholesterol

Hormone Replacement Therapy - Findings advance knowledge in hormone replacement therapy research

Hormone Replacement Therapy - Once- and twice-weekly matricial estradiol transdermal systems compared

Hormones - Databases largely underestimate the amount of enterolignan precursors in foods

Hormones - Progesterone-binding protein studied, expression and up-regulation clarified

Human Papillomavirus - Ability to mass produce HPV may lead to gains against cervical cancer

Human T-Lymphotropic Virus Type 1 - CD8+ cells are major determinant of HTLV-1 proviral load

Huntington Disease - 2.7x increase in proliferating cell nuclear antigen+ cells in Huntington disease

Hyperhydrosis - BOTOX approved for hyperhydrosis treatment in Germany

Hyperlipidemia - Statin and fibrate therapies combine for a safe treatment for hyperlipidemia

Hyperparathyroidism - Gland size is linked to genetic changes in sporadic parathyroid adenomas

Hypertension - Researchers detail new studies and findings in the area of hypertension

Hypertension - Review discusses involvement of 5-HT in hypertension

Imaging - HCS creator launches the KineticScan HCS Reader Version 2.2.0

Imaging - Myocardial tagging may reduce the need for high-dose dobutamine stress

Imaging - New image guided brachytherapy suite introduced

Imaging - Ultrasound imaging company signs distribution agreement with Maximum Medical

Immunology - Blood glutathione may be a marker of antioxidant defense consumption

Immunology - Findings advance knowledge in immunology research

Immunology - Plasmacytoid DC may have an immunogenic effect in setting of VLP vaccination

Immunotherapies - Antigen specific active immunotherapy potential still untapped

Inflammatory Bowel Disease - Targeting genes to inflamed intestine through luminal route is feasible

Inflammatory Response - Effects of volumetric vs. pressure-guided fluid therapy compared

Influenza - Single dose of influenza vaccination shows better action than booster dose

Influenza Vaccine - Drug master file for cell-derived influenza vaccine submitted to U.S. FDA

Influenza Vaccines - Research add new data to influenza vaccines body of knowledge

Information Technology - Grant received from U.S. NIH to develop brain mapping software

Information Technology - Physician survey shows access to diagnostic software improves health care

Information Technology - Rcopia e-prescription system selected for phase II of Ohio Patient Safety grant

Information Technology - Solution launched for quantitative proteomics

Intra-Articular Drug Delivery - Rotating dialysis cell model simulates drug kinetics in knee joint

Intrauterine Growth Restriction - Dexamethasone use in early pregnancy poses IUGR risk

Ischemia - Gelatin complexes with adrenomedullin DNA target chronic heart disease

Ischemia - New findings in ischemia described

Islet Transplantation - New research in the area of islet transplantation detailed

Kaposi Sarcoma-Associated Herpesvirus - High incidence of KSHV infection in HIV-related lymphoproliferative disorders

Kaposi Sarcoma-Associated Herpesvirus - Kaposi sarcoma in HHV-8+ gay males more common among whites and educated persons

Keratitis - InSite Vision's AzaSite effective in pseudomonas-induced keratitis

Kidney Transplantation - C2 CsA monitoring improves outcome and lowers costs

Legal Issues - Cancer device companies announce settlement of arbitration by mutual consent

Legal Issues - IVAX responds to U.S. District Court ruling on clarithromycin ER

Legal Issues - Israel-based generic drug company comments on U.S. district court's injunction

Legal Issues - Nicodrops settles lawsuit

Leukemia - New variant t(6;15;17)(Q25;q22;q21) in acute promyelocytic leukemia discovered

Leukemia - Researchers provide details of new studies and findings in the area of leukemia

Lipid Research - In vitro models simulate hepatitis C virus genotype 3a-related steatosis

Liposomal Encapsulation - Liposomal oligopeptide-rich casein hydrolysates prepared

Listeria - Dendritic cells process & present Listeria antigens for CD4+ T cell priming

Listeriosis -  L. meningitis should be ruled out in patients with neurology symptoms

Lung Cancer - Benefit of respiration-gated stereotactic radiotherapy for lung cancer examined

Lung Cancer - Dose escalation achievable in treatment of non-small-cell lung cancer quantified

Lung Cancer - Pharmaceutical management of patients during lung cancer chemotherapy advised

Machado-Joseph Disease - Lamotrigine therapy can reduce gait disturbance

Mad Cow Disease - Joint venture formed for the development of mad cow disease diagnostics

Malaria - Clinical trial studies malaria drug treatment in Uganda

Malaria - Molecular markers studied as drug-resistance markers in malaria

Malaria - Pharma company partners with East African Botanicals for antimalarial ingredient

Malaria Therapy - Artesunate improves efficacy of sulfadoxine-pyrimethamine treatment

Malaria Therapy - WHO drives efforts to boost antimalarial drug supply

Malignant Mesothelioma - D2-40 and podoplanin specific/sensitive markers of malignant mesothelioma

Market Analysis - Biotech continued its steady improvement in May

Market Analysis - Pharma market research teams collect competitive intelligence

Measles Virus - AIK-C and CLL vaccines elicit durable protective immunity in young infants

Medical Abortion - Coadministration of mifepristone, misoprostol is safe up to 49 days gestation

Medical Devices - IMPAC supports Varian 4D integrated treatment console

Medical Devices - Protein crystal screening system launched

Medical Devices - TriVersa NanoMate launched for mass spectrometry

Medicare - Consumer health organization expands its Medicare advantage plan in Texas

Medicare - Health benefits company bids to offer Medicare Part D Prescription Drug Plan

Medicare - Health plan affirms intent to participate in Medicare Part D

Medicare - Health plan company to offer AARP-branded Medicare drug plan

Medicare - Healthcare consultant group offers guidance for Medicare drug benefit providers

Medicare - Healthcare organization details plans of its Medicare Advantage HMO launch

Medicare - Humana's Medicare geographic reach to nearly double in 2006

Medicare - Managed care organizations see opportunities in new Medicare drug benefits

Medicare - Minnesota health benefits company expands Medicare product for seniors

Menopause - Gene polymorphisms guide the timing of female menopause

Mental Health - Brain monitoring technology predicts changes in suicidal ideation

Mental Health - New Michigan Medicaid program improves care for mental illnesses

Mergers & Acquisitions - Biopharma marketing services company announces sale to In2Focus

Mergers & Acquisitions - Clinical research organization acquires two consultancies

Mergers & Acquisitions - Health services company completes acquisition of SpectraCare, Inc.

Mergers & Acquisitions - Innovative Medical Services, LLC acquires Fillmaster and Nutripure

Mergers & Acquisitions - Medical device company acquires assets for cervical plate technology

Mergers & Acquisitions - NanoViricides acquisition complete

Mergers & Acquisitions - Nutritional supplement corporation to acquire vitamin and herb company

Mergers & Acquisitions - Peptide company acquires Green Machine Investments

Metabolic Disease - Researchers seek to prevent metabolic issues in subjects on anti-psychotics

Metabolic Syndrome - Higher testosterone and SHBG levels in men reduce risk of metabolic syndrome

Microcirculation - Effects of T-3 and T-4 on hamster cheek pouch microcirculation

Microencapsulation - Chitosan-coated microspheres produced via emulsification/internal gelation

Microencapsulation - Researchers provide guidance for CTL vaccines using microspheres

Minimal Change Nephrotic Syndrome - Ketoconazole reduces CsA dose requirements in children

Monoclonal Antibodies - Researchers reveal second binding site for Gas6-receptor interaction

Multiple Myeloma - Data on protein 90 inhibitor from clinical trials in multiple myeloma presented

Multiple Sclerosis - Cell therapy company announced interim results of Tovaxin trials

Mycobacteriology - Decontamination methods affect recovery of mycobacteria from clinical specimens

Mycobacterium Avium - Viable M. avium subsp paratuberculosis detected in milk by culture and PCR

Mycobacterium Tuberculosis -  M. tuberculosis PGDH is link between E. coli and mammalian enzymes

Mycobacterium Tuberculosis - Adenylate cyclase proteins expressed simultaneously in MTB & M. leprae

Mycobacterium Tuberculosis - OtsAB pathway essential for trehalose biosynthesis in M. tuberculosis

Mycobacterium Tuberculosis - Pyrosequencing assay detects SNPs in M. tuberculosis embB306 region

Myelodysplastic Syndrome - REVLIMID new drug application accepted for review by FDA

Myocardial Infarction - Recent studies add new data to myocardial infarction research

Myocardial Infarction - Risk of heart attack may increase with certain anti-inflammatory drugs

Nanotechnology - Nanotech stem cell device licensed from Stanford University

Nasal Irrigation - Effects of intranasal saline sprays on ciliary beat frequency compared

Neisseria Meningitides Epidemiology -  N. meningitides serogroup W135 exceeds 40% in nonepidemic regions of Niger

Nephrology - Gelatin matrix treatment of complex renal injuries in a porcine model

Neural Stem Cell Research - ABCG2 transporter functionally expressed in neural stem/progenitor cells

Neural Stem Cell Research - Neurosphere assay is valuable tool for isolating/understanding embryonic NSCs

Neural Stem Cell Research - Overexpressed Sox6 can induce astrocytic differentiation

Neuroprotection - Neural tube defects examined, peptide-mediated protection revealed

Neuroscience - Angiogenic proteins outline the course of brain arteriovenous malformations

Neuroscience - Connection between cell phone use and brain tumors studied

Neuroscience - Men with sleep apnea syndrome display serotonin transporter gene variations

Neuroscience - Nicotine differentially affects neurotransmitter-regulating nAChRs

Neuroscience - Research program to develop new approach to Alzheimer disease therapeutics

Neuroscience - Studies add new findings to neuroscience body of knowledge

Neuroscience - Study confirms blood brain barrier penetration of AL-108 and AL-208

Neurosurgery - Propofol, sevoflurane provide comparable anesthesia with remifentanil

Neurotensin - Neurotensin studied, stimulation of interleukin-8 expression revealed

Neurotransmission - Inhibition of transmitter release studied, role of bradykinin defined

Newborn Health - Study shows NICU babies exposed to high levels of phthalate

Non-Small Cell Lung Cancer - Report: Avastin will account for more than 50% of market in 2014

Obesity Complications - Pharmacokinetic considerations of anesthesia in obese patients reviewed

Obesity Research - Data on Oleoyl estrone presented at obesity conference

Obesity Research - Obesity awareness organization joins forces with 16 organizations

Obesity Therapy - Drug treatment of obesity reviewed

Obesity Therapy - Islet amyloid polypeptide regulates energy homeostasis

Obesity Therapy - Orlistat and weight-loss techniques helpful in improving weight management

Obesity Therapy - Pharmacological therapies for obesity discussed

Obstetrics - Cancer drug could aid premature labor

Obstetrics - Cost-effectiveness of prophylactic LMW heparin in pregnant women assessed

Obstetrics - Researchers describe findings in obstetrics studies

Oncogenesis - Deregulated genes are not breast cancer factors in WAP-SVT/t transgenic animals

Oncogenesis - Transcription factor Spz1 exhibits proto-oncogene activity

Oncology - Agents targeting KIT exon 8 mutations may treat core-binding factor leukemia

Oncology - Antigene peptide nucleic acid cuts neuroblastoma growth via MYCN inhibition

Oncology - Ephrin-A1 causes poor outcomes in alpha-fetoprotein-producing liver cancer

Oncology - Morphometric study depicts facets of acute lymphoblastic leukemia angiogenesis

Oncology - New findings in the area of oncology described

Orthopedics - Cytokine transfected tissue implants may avert aseptic loosening

Osteogenesis - Local transforming growth factor-beta strengthens bone regeneration

Osteoporosis - Researchers' work adds to osteoporosis body of knowledge

Osteoporosis - Study finds alendronate comparably cost effective to other therapies

Ovarian Cancer - Introgen's INGN 241 activates tumor selective cell death pathways

Ovarian Cancer - Researchers' findings advance ovarian cancer research

Paclitaxel - Apoptosis induced by 5-fluorouracil, cisplatin and paclitaxel in gastric cancer

Pain Management - Canadian regulatory approval granted for peripheral neuropathy treatment

Pain Management - Cellegesic launched in the United Kingdom

Pain Medicine - Biopharma company completes enrollment in phase III study of Remoxy

Pain Medicine - Effects of topical NSAID formulations on quality of life compared

Pain Medicine - Survey highlights need for primary care guidance on NSAID use

Pain Medicine - Trazodone studied in insomnia caused by somatoform pain disorder

Pancreatic Cancer - New advances may slow tumor growth in pancreatic cancer

Pancreatic Cancer - Novel anti-pancreatic cancer agent LY293111 discovered

Pancreatic Cancer - Virulizin granted orphan drug status in the European Union

Parkinson Disease - Neurosurgical gene transfer procedure trial results reported at conference

Partial Gastrectomy - Four-drug regimen eradicates postoperative H. pylori colonization

Patents - European Patent Office grants patent allowance to protect anticancer drug

Patents - European patent grant for immune-enhancing adjuvant

Patents - European patent granted for novel target for diabetes treatment

Patents - InSite Vision Announces Issuance of an EPO Patent on Azalide Antibiotics

Patents - Introgen wins European patent decision on p53 gene therapeutic applications

Patents - Pain-management company reports favorable outcome in generic oxycodone case

Patents - Patent issued for drug screening methods for metabolic-related disorders

Patents - Rice bran nutrient company granted patent for arthritis and joint health

Patents - U.S. Patent office issues 2 patents to cardiovascular-focused drug company

Patents - U.S. patent allowed on pre-sensitizing cancer prior to treatment

Patents - U.S. patent issued for stabilized hydroxyvitamin D

Patents - U.S. patent received for nanoscale photovoltaic cell design

Patient Safety - Patient-friendly packaging, labeling launched for anaphylaxis auto injectors

Pediatric Hepatology - Demographics influence fatty liver disease risk factors in obese adolescents

Pediatrics - Research on pediatric applications of drugs launched in Europe

Percutaneous Coronary Intervention - Use of drug-eluting stents lowers complication risk

Peritoneal Dialysis - CA125 examined, limitations as an index of peritoneal mesothelial mass shown

Peritoneal Malignant Mesothelioma - P16 loss/mitotic rate predict poor survival in peritoneal malignant mesothelioma

Personnel - Antibody-focused biotech appoints CFO, vice president, business development

Personnel - Biopharma firm appoints John Nieland as VP preclinical research

Personnel - Biopharma firm appoints Sharon E. Tetlow senior VP, chief financial officer

Personnel - Biotech company appoints Manfred Ruediger as chief operating officer

Personnel - Biotech company appoints Michael T. Dwyer as president, CEO, director

Personnel - Biotechnology company announces senior management change and relocation

Personnel - Contract research company names new controller

Personnel - Dale Rieger joins consultancy; will advise biotech and pharma clients

Personnel - David R. Bethune joins therapeutics company's board of directors

Personnel - Dr. Ruedi E. Waeger joins board of directors of THYMITAQ maker

Personnel - Drug and device maker appoints president and CEO

Personnel - Drug process development company appoints William Haseltine advisor to board

Personnel - Healthcare interactive marketing agency expands capabilities with new hires

Personnel - IT company names Anahita Villafane as CFO

Personnel - Imaging company names Roberto Molteni as executive VP of technology

Personnel - James D. Houston named VP, general counsel by healthcare staffing company

Personnel - James Posada, PhD, MBA named senior VP of business and market development

Personnel - Jerome M. Hauer named to board of vaccines-focused biosciences company

Personnel - Kevin Lee named acting CFO by company focused on infectious disease therapies

Personnel - New CFO added to management team at biopharmaceutical firm

Personnel - Nutritionist/hygienist rejoins dental practice

Personnel - Pharma and medical delivery system company appoints CFO

Personnel - Pharma company announces promotions

Personnel - Pharma company appoints president and chief executive officer

Personnel - Pharma company names senior vice president, business development

Personnel - Pharmaceutical company names copresident

Personnel - Sylvia McBrinn to head pharmaceutical company's U.S. commercial operations

Personnel - Vered Caplan named acting CEO of immunotherapy maker

Pharmaceutical Research - Pharmacy benefit manager studies impact of over-the-counter antihistamine

Pharmaceutical Science - Novel sample prep method improves polymorph analysis

Pharmaceuticals - Effects of aging on aerosol properties of amorphous FK888 determined

Pharmaceuticals - Pharma company reports results for micellar nanoparticle technology studies

Pilonidal Sinus - Fibrin glue used to treat pilonidal sinus

Pituitary Gland - Apoplexy in pituitary macroadenoma described

Pneumococcal Pneumonia - IL-10 improves ceftriaxone pharmacokinetics in mice

Post-Herpetic Neuralgia - Positive results with prodrug of gabapentin for post-herpetic neuralgia reported

Preventive Medicine - Many United States military recruits show immunity to hepatitis B infection

Prions - Findings in prions provide new insights

Prions - Scrapie analyzed, PrPSc propagation with different PrP genotypes defined

Prison Health - Substance abuse treatment facility opens in Casper, Wyoming

Prodrugs - Antitumor prodrugs Cloretazine and BCNU evaluated

Product Licensing - DNA-focused biopharmaceutical company licenses 3 cancer vaccine targets to Merck

Product Licensing - Inpharmatica licenses Admensa Interactive to Daiichi

Product Licensing - New River enters into development and license agreement

Prolactin - Potential clinical uses of human prolactin receptor antagonists studied

Prostate Cancer - 'Nutrition and Prostate Cancer Guide' issued by foundation

Prostate Cancer - Acute toxicity occurred during 3DCRT treatment for prostate cancer

Prostate Cancer - Cancer cells transduced ex vivo stimulate antitumor immunity in mice

Prostate Cancer - Efficacy of androgen deprivation therapy examined

Prostate Cancer - Functional epigenomics identifies genes frequently silenced in prostate cancer

Prostate Cancer - Inducible caspase and interleukin-12 combine well to fight prostate cancer

Prostate Cancer - Medical products supplier launches technology for prostate cancer treatment

Prostate Cancer - Outcomes of radical prostatectomy revealed

Proteomics - Genetic screening provider launches BioXPRESSION Biomarker

Proteomics - Researchers describe findings in proteomics studies

Proteomics - Study to evaluate PhosphoScan platform

Proteomics - Ultrasound method can augment organ-specific delivery of proteins

Psoriasis - Tumor necrosis factor enzyme studied, overexpression in psoriasis observed

Pulmonary Arterial Hypertension - FDA approves Revatio as treatment for PAH

Pulmonary Medicine - Daptomycin examined, inhibition by pulmonary surfactant revealed

Pulmonary Medicine - Findings advance knowledge in pulmonary medicine research

Q Fever Outbreak - North wind containing aerosolized C. burnetii influenced Q fever outbreak

Recombinant Research - A new vector system eases DMBT1 variant and full-length cloning

Renal Cancer - Gastrin releasing peptide receptor modulates angiogenesis and tumor growth

Renal Cell Cancer - Phase II study of flavopiridol in advanced renal cell carcinoma conducted

Renal Transplantation - Data support early introduction of fluvastatin in renal tx patients

Respiratory Medicine - Asthma is still in session, even during summer break

Respiratory Medicine - Keratinocyte growth factor therapy shows promise for acute lung injury

Rheumatoid Arthritis - Data from Rituzan rheumatoid arthritis trial announced

Rheumatoid Arthritis - Study shows targeted B cell therapy effective in treating rheumatoid arthritis

Rhinosinusitis - Fluticasone propionate for nasal polyposis, rhinosinusitis reduces surgery need

Rotavirus Outbreaks - Rotavirus enteritis outbreak occurred in adult transplant recipients

SARS - UIC developing drug for SARS

SARS Coronavirus - Findings describe new data in SARS coronavirus research

Sclerotherapy - Novel, nonsurgical management of orbito-palpebral cyst studied

Seborrheic Dermatitis - Company to resume Extina development with new phase III trial

Sepsis - Functional modification of dendritic cells may be novel approach against sepsis

Sexual & Reproductive Health - New treatments to enhance quality of life for women presented at conference

Sexual & Reproductive Health - Researchers present findings on men's health issues at conference

Sexual & Reproductive Health - Wurn Technique infertility treatment now available in Midwest U.S.

Sexually Transmitted Disease Risk - Circumcision associated with self-reported urethral discharge/genital ulcer

Sexually Transmitted Disease Risk - Sexual risk behavior patterns change among STI clinic patients

Shingles - Experimental shingles vaccine proves effective in nationwide study

Skin Cancer - Use of sunscreen down as skin cancer rates increase, new survey shows

Sleep Disorders - Many drugs prescribed for chronic insomnia not approved for that purpose

Spider Envenomation - Four treatments for brown recluse spider bites compared

Spinal Cord Injury - Gene therapy company presented Innurex preclinical efficacy data

Squamous Cell Carcinoma - Phase III trial shows Erbitux and radiation control spread of cell cancer

Staphylococcus Aureus - Community-acquired Staphylococcus aureus infections in children studied

Statins - Fluvastatin may be more beneficial to patients with the -786C allele

Statins - Treatment with simvastatin for 3 days results in 24% drop in LDL-C

Stem Cell Research - B-cell/myeloid common progenitor does not express CXCR4

Stem Cell Research - Early lymphoid progenitors are highly sensitive to glucocorticoids

Stem Cell Research - Flt3+ lympho-myeloid stem cell population lacks erythro-megakaryocytic potential

Stem Cell Research - Increased Cux-1 expression may play role in activation of hepatic stem cells

Stem Cell Research - Pontine noradrenergic A5 neurogenesis requires brain-derived neurotrophic factor

Stem Cell Research - Research shows public support for stem cell research

Stem Cell Transplantation - Anti-infective mouth rinse does not decrease oral microbial burden after ASCT

Stem Cell Transplantation - CD34+ cell dose strongly correlates with successful APBSCT engraftment in AML

Stem Cell Transplantation - Pretransplant disease burden associated with worse outcome following SCT

Stress Urinary Incontinence - Combined pelvic floor muscle training and duloxetine is effective treatment

Stress Urinary Incontinence - Study compares porcine dermal implant and silicone injection for SUI treatment

Stroke - Losartan ameliorates cerebral focal ischemia in rat models

Stroke - National institute recommends treatment for stroke patients

Stroke - Positive results reported in development of stroke treatment

Suicide - Maine deaths due to drug misuse in 2003 released

Surgical Technology - Advanced Medical Optics to Change NYSE Ticker Symbol to 'EYE' Effective June 8

Tamoxifen - Aromatase inhibitors compared to antiestrogens

Tetanus Vaccine - Single dose tetanus vaccine formulation developed

Thrombosis - Dipyridamole/cilostazol combination may be a new antithrombotic therapy

Thyroid Cancer - Liposomal doxorubicin holds promise as therapy for thyroid cancer

Tissue Engineering - 3D structure developed as a precursor for tissue and organ regeneration

Tissue Engineering - Collagen and PHBV matrices developed for cartilage tissue engineering

Tissue Engineering - Electrospun fine-textured scaffolds used for heart tissue constructs

Tissue Engineering - Nanocomposite scaffolds developed for hard tissue regeneration

Tissue Engineering - Osteoblast growth and differentiation enhanced on peptide hydrogel

Tissue Engineering - Perfusion fed bioreactor generates embryonic stem cell-derived cardiomyocytes

Tobacco Use - Study confirms Internet can provide real support for smokers who want to quit

Toxoplasmosis - Potential chemotherapeutic target for the treatment of toxoplasmosis studied

Transplant Medicine - Adefovir proves safe for liver recipients with drug-resistant hepatitis B

Transplant Medicine - Anti-TNF-alpha therapy treats acute rejection in intestinal transplantation

Transplant Medicine - Data advance knowledge in transplant medicine research

Transplant Medicine - Liver transplant success improves by managing levels of antirejection drugs

Transplant Medicine - Patient and graft variables predict post-liver transplantation mortality

Transplant Medicine - Pharma company provides regulatory update on PULMINIQ

Transplant Medicine - Protocol improves outcomes in elderly recipients of kidneys from cadaver donors

Tuberculosis - Molecular epidemiology helps understand tuberculosis transmission & pathogenesis

Tuberculosis - Recent TB transmission associated with health-care work in low incidence setting

Tuberculosis - Retreatment can cure most patients with multildrug-resistant tuberculosis

Tuberculosis Surveillance - Screening household contacts improves tuberculosis case detection rates

Tuberculosis Therapy - Promising new TB drug enters clinical trial

Type 1 Diabetes - FMDI regimen is good alternative to MDI in preschool-aged children

Type 2 Diabetes - Further studies needed on fluoxetine and paroxetine in type 2 diabetic patients

Type 2 Diabetes - Lowering resistance to insulin may delay or prevent onset of diabetes

Type 2 Diabetes - Newer long-acting agents provide better level of basal insulin than older ones

Type 2 Diabetes - Study reveals leading research on the benefits of using insulin earlier

Urothelial Cancer - Oral farnesyl transferase inhibitor treated urothelial transitional cell cancer

Vaccine Development - Bacterial ghosts facilitate hepatitis B antigen delivery

Vaccine Development - Immunostimulatory adjuvant may be key to hepatitis C vaccine efficacy

Vaccine Development - Introgen's INGN 241 effective against multiple cancers in preclinical studies

Vaccine Development - Oligonucleotide prototype boosts immunological response to hepatitis B vaccine

Vector Development -  Bifidobacterium infantis transmits suicide gene therapy to melanoma cells

Vector Development - Calcium strengthens plasmid-lipid particle transfection

Vector Development - Findings in vector development provide new insights

Vector Development - Nanoparticulate drives adenoviral gene constructs into refractory cell targets

Ventilator-Associated Pneumonia - Predictors of Acinetobacter baumannii VAP identified

Ventricular Coupling - Model can describe interaction of LV, aortic valve, and arterial system

Vibrio Cholerae -  V. cholerae AphA is member of winged helix transcription factor superfamily

Viral Genome Analysis - Bioinformatics tool used for viral genome analyses

Virology - Adenovirus vector E4 regulates endothelial cell connexin expression

Virology - Hepatitis C genotype 1b flourishes in a Spanish liver transplant unit

Virology - New data illuminates research in virology

Vulvovaginal Candidiasis - Species associated with recurrent episodes tend to be less azole susceptible

Weight Management - Pharmacologic treatment of obesity reviewed

West Nile Virus - Company announces third year of its West Nile virus trial

West Nile Virus - Researchers' work adds to west nile virus body of knowledge

Wound Care - Vascular endothelial growth factor antagonism disrupts wound healing

Wound Healing - Fibrin clot adhesion examined, success of protein-conditioned dentin reported

Wound Healing - Histone H1.2 is a potential antimicrobial agent

Yersinia Pseudotuberculosis - 3 identical Y. pseudotuberculosis isolates had no epidemiologic relationship

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