Cancer Immunotherapy
Reengineered dendritic cells need natural killer cells for melanoma targeting
Published in Drug Week, July 8th, 2005
According to a study from the United States, "tumor antigen gene-modified dendritic cells (DC) generates robust antigen-specific protective antitumor responses. Though the role of CD4 positive and CD8 positive cells in the immunological response to gene-modified DC has been well-characterized, the role of NK cells in this response has been somewhat less clear."
"Owing to the significant contribution of innate immunity in other model systems, we postulated that NK cells would hold a critical position in the generation of an immune response following immunization with tumor...
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Source: Drug Week (2005-07-08)
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