Published in Drug Week, July 8th, 2005
According to recent research from the United States, "Patients with prostate cancer are treated with neoadjuvant, adjuvant and intermittent therapy with gonadotropin-releasing hormone agonists (GnRH-A). While these are largely successful in decreasing testosterone (T) and dihydroxytestosterone (DHT) to castrate levels, discontinuation of such therapy often results in continued suppression of androgens for variable periods of time."
"We present the largest published series of patients evaluating the timing of T and DHT increase after cessation of GnRH therapy. Serial T and DHT...
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