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Drug Week

Susan Hasty, Publisher

Table of Contents . . . July 29th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Attention-Deficit Hyperactivity Disorder - Data: Patients on Concerta more likely to continue with long-term therapy

Cancer Therapy - Long-term benefits of Aldara cream for actinic keratosis reported

Depression - Company announces positive phase III results for Gepirone ER

Pain Medicine - Humira improves quality of life for psoriatic arthritis patients

Protein Kinase - Protein kinase C studied, influence on transcription of ZO-1 and occludin shown

Acintobacter Baumannii -  A. baumannii outbreak caused by bla(OXA-21) determinant

Acute Coronary Syndrome - EARLY ACS trial designed to reinforce benefit of early use of Integrilin

Addiction Medicine - New findings in addiction medicine described

Adenovirus - Adenovirus DNA detected by SYBR Green real-time PCR assay

Adriamycin Nephropathy - Naked DNA encoding MCP-1 and RANTES protects against renal injury

Angiology - Studies add new findings to angiology body of knowledge

Adverse Drug Reaction - Genomics researchers discover protein deficit that causes drug toxicity

Age Related Macular Degeneration - Chorioretinal anastomoses predict trouble after photodynamic therapy

Age Related Macular Degeneration - Company completes SPA with FDA for EVIZON in AMD

Aging - Aging studied, hepatic antioxidant capacity and oxidative injury programmed

Allergy Medicine - Anti-inflammatory activity of Korean folk medicine 'Sabaeksan' analyzed

Allergy Medicine - Mast cell degranulation and allergies studied, role of T cell kinase revealed

Cardiology - Researchers publish new studies and findings in the area of cardiology

Allergy and Immunology - Immunoglobulin G3 is crucial for antibody secretion but not antigen specificity

Allergy and Immunology - Lymphatic tissue does not support hepatitis B replication in carriers

Allergy and Immunology - Patients coinfected with hepatitis C and HIV mount a full response to F protein

Alzheimer Disease - Somatostatin regulates amyloid beta peptide metabolism

Alzheimer Disease - Study showes Colostrinin can prevent the aggregation of beta amyloid

Amyotrophic Lateral Sclerosis - Study falls short of showing efficacy of high dose vitamin E therapy

Dermatology - Recent findings in dermatology described

Anemia - U.S. FDA approves IV therapy for iron deficiency anemia in pre-dialysis patients

Anesthesia - Clonidine is a safe and effective alternative to epinephrine in oral surgery

Anesthesia - Gramicidin A dynamics examined, influence on anesthesia clarified

Anesthesia - I.V. anesthetics restore cerebral autoregulation; volatile anesthetics do not

Angiology - Reports advance knowledge in angiology research

Diabetes Therapy - Recent findings in diabetes therapy provide new insights

Angiotensin - Angiotensin type analyzed, receptor antagonist activity documented

Anicemycin - Anicemycin inhibited anchorage-independent growth of tumor cells

Antibacterial Agents - Elafin gene transfer fights pulmonary Staphylococcus aureus infection

Antibiotics - Model membranes studied, reaarangement by peptide antibiotic NK-2 revealed

Antioxidants - Research add new data to antioxidants body of knowledge

Antipsychotic Therapy - Astrocytes mediate suppressive effects of clozapine on GLT-1 activity

Diagnostics - New findings in the area of diagnostics described

Antiviral Therapy - Researchers' work adds to antiviral therapy body of knowledge

Apoptosis - Induction of NO and ROS caused apoptosis in lymphoma cells

Apoptosis - T-lymphocyte apoptosis studied, nature of increase defined

Arrhythmia - Ibutilide is effective at terminating atrial arrhythmias

Arrhythmia - Use of ACE inhibitors and ARBs in the prevention of AF needs further study

Aspergillosis - SMX might be effective against Aspergillus

Enzymology - New findings in the area of enzymology described

Asthma - Pennsylvania launches asthma project for kits

Asthma - Quality improvement organization wins proposal for Oregon asthma study

Asthma Therapy - Salmeterol HFA and CFC inhalers have equivalent efficacy

Atherosclerosis - Apoptotic cell phagocytosis studied, impairment in atherosclerosis noted

Atherosclerosis - MRI shows statin therapy shrinking plaques

Atherosclerosis - Pioglitazone has anti-atherosclerosis activity in diabetic patients

HIV/AIDS Pathogenesis - Researchers' findings advance HIV/AIDS pathogenesis research

Atrial Fibrillation - Anti-inflammatory therapy may decrease AF incidence after cardiac surgery

Autism - Risperidone safe, effective as intermediate term treatment for autism

Avian Influenza - New avian influenza genotype present during the 2003-04 Asian bird flu outbreaks

Awards - Slovenia group awards prize for generic controlled-release gastric pellets

Bacillus Anthracis - Anthrax lethal toxin induces endothelial barrier dysfunction

Benign Prostatic Hyperplasia - Prolonged-release tamsulosin tablet for benign prostatic hyperplasia launched

HIV/AIDS Pathogenesis - Studies add new findings to HIV/AIDS pathogenesis body of knowledge

Benign Prostatic Hyperplasia - Registrational program for lonidamine treatment for benign prostatic hyperplasia

Bioartificial Liver - Microfabricated grooved substrate is platform for bioartificial liver reactors

Biochemistry - CE device seperates 6OCOL and N6OCOL diastereoisomers

Biomedical Engineering - Dual porosity expanded polytetrafluoroethylene supports tissue healing

Biomedical Engineering - Matrix molecules allow cells to create cardiovascular tissues

Biotechnology - Life science company adds senior vice president human resources

Obesity Therapy - Researchers' data advance obesity therapy research

Bioterrorism - Antibiotic nonadherence is a concern for future bioterrorist events

Blood Banking - Quality issues found in banked umbilical cord blood stem cells for transplant

Blood Pressure - Beta-1 adrenoceptor blockade mediates the cardiovascular effects of khat chewing

Blood Safety - Filtrations company and Fresenius Kabi AG partner to reduce prions

Blood Safety - Multitransfused thalassemic children show a risk for acquiring hepatitis C

Bone Cancer Pain - Analgesic effects of loperamide in bone cancer pain in mice analyzed

Obesity Therapy - Researchers' work adds to obesity therapy body of knowledge

Brain Cancer - Brain tumor types express VEGF and its receptors differentially

Brain Cancer - Hairpin siRNA identifies and shuts down glioma progression factors

Breast Cancer - Arimidex granted new indication enabling wider access

Breast Cancer - Clinicopathologic factors linked to false-negative sentinel lymph-node biopsy

Breast Cancer - Duke University to evaluate Panzem NCD in breast cancer

Breast Cancer - New findings in the area of breast cancer described

Oncology - Studies describe new findings in oncology research

Breast Cancer - Phytoestrogens and 17 beta-estradiol inhibited apoptosis in breast cancer cells

Breast Cancer - Postmenopausal hormone replacement therapy and risk of cancer debated

Breast Cancer - Reovirus may be used as a purging modality for breast cancer during ASCT

Breast Cancer - U.S. patent for breast cancer detection through biomarkers granted

Brucellosis - Tc-99m HIG scintigraphy helps diagnose osteoarticular involvement in brucellosis

Business & Finance - Cancer-focused corporation secures $30 million in private equity financing

Tissue Engineering - Researchers' findings advance tissue engineering research

Business & Finance - Spanish biotech board authorizes raising funds through institutional investors

Business Update - Biomedical R&D hub expansion confirms Singapore's role in scientific community

Business Update - Biotech company appoints new directors, provides corporate update

Business Update - Clinical research organization adds early-phase clinical development services

Business Update - Company is awarded grant for systems biology proteomics platform

Business Update - Company raises sales forecast for Macugen (pegaptanib sodium injection)

Transplant Medicine - Recent findings in transplant medicine described

Business Update - Company to launch DispenseQuick division

Business Update - Drug distributor to join the new Russell Microcap Index

Business Update - EpiPen maker announces layoffs

Business Update - FDA approves of BALACET 325

Business Update - Gene-based company to list on NASDAQ

Business Update - Group formed to focus on nanotechnology investments

Virology - Researchers' work adds to virology body of knowledge

Business Update - MCAA business sold to Gilde

Business Update - Marketing for pharma company's subsidiary generates $2.5M in new orders

Business Update - New consumer relationship marketing company launched

Business Update - New lease signed for vaccine manufacturing operations

Business Update - Paxil CR maker announces resupply to U.S. market

Business Update - Pharmaceutical company launches corporate social responsibility report

Business Update - Research facilities consolidated in preparation for expanded operations

Business Update - Tamiflu development and licensing agreement terminated

Business Update - U.S. FDA approves Acthar API manufacturing transfer

Business Update - Zonegran launched in the U.K. and Germany

Calcific Aortic Stenosis - Intensive lipid-lowering therapy does not stop progression of stenosis

Cancer Prevention - The farnesyltransferase inhibitor ABT-100 prevents liver cancer

Cancer Prognosis - Prognostics of cancer of unknown primary reviewed

Cancer Therapy - Alliance to accelerate clinical development and commercialization of Ceflatonin

Cancer Therapy - Antibodies to angiogenic protein staunch murine acute myeloid leukemia

Cancer Therapy - Company licenses rights to seocalcitol from LEO Pharma

Cancer Therapy - Induced p14ARF drives p53-dependent cell cycle arrest but not apoptosis

Cancer Therapy - New data illuminates research in cancer therapy

Cancer Therapy - Positive phase-II data reported on pegylated interferon alfa-2b

Cancer Therapy - Proliferative indices predict survival after chemotherapy for breast cancer

Cancer Therapy - Small molecule inhibitors knock down hypoxia-related tumorigenesis

Cancer Treatment - Study probes perceptions, attitudes of oncologists' drug therapy choices

Cancer Vaccine - 5-Fluorouracil enhances efficacy of conditionally replicating herpes

Cancer Vaccines - Reports add new data to cancer vaccines research

Candida Albicans - N-cadherin mediates endocytosis of Candida albicans by endothelial cells

Cardiac Myxoma - Caspase-3-dependent apoptosis in cardiac myxoma not associated with HPV or EBV

Cardiology - Medical technology company initiates patent foramen ovale closure study

Cardiology - New findings in cardiology described

Cardiology - Protein kinase C examined, role in neonatal cardiac structure clarified

Cardiology - Spray nitroglycerin brings fast relief for angina

Cardiology - Thrombospondin-1 buffers non-affected tissues following myocardial infarction

Cardiopulmonary Bypass - Long-term renal replacement therapy post cardiopulmonary bypass is not likely

Cardiovascular Disease - Company awarded major clinical research program in cardiovascular disease

Cardiovascular Disease - FM-VP4 toxicity study complete

Cell Biology - Cultured parotid acinar cells retain functional capacity for exocrine studies

Cerebral Embolism - Patients with AF and dense SEC at high risk for cerebral embolism

Cervical Cancer - Chemotherapy included in primary treatment of cervical carcinoma

Cervical Cancer - Researchers describe findings in cervical cancer studies

Cesarean Delivery - Buccal misoprostol is useful adjunct during cesarean delivery

Chemotherapy - Adjuvant anthracycline-based chemotherapy for early breast cancer evaluated

Chemotherapy - Temozolomide used to treat high-grade gliomas

Chronic Heart Failure - Biopharmaceutical company reports results of treatment for chronic heart failure

Chronic Heart Failure - Carvedilol improves left ventricular diastolic function in advanced CHF

Chronic Hepatitis C - Studies add new findings to chronic hepatitis c body of knowledge

Chronic Liver Disease - Auto-antibodies are unsuitable for diagnosing cholestatic liver diseases

Chronic Liver Disease - Matrix metalloproteinase gene variations associate with liver diseases

Chronic Liver Disease - Occult hepatitis B infection masks viral gene expression

Chronic Liver Disease - Three dimensional software enriches liver resection and transplantation

Chronic Obstructive Pulmonary Disease - Foradil Certihaler approved in Germany

Chronic Small Airway Disease - Macrolides efficacy evaluated in CAD mimicking diffuse panbronchiolitis

Classical Swine Fever - U.S. classical swine fever isolates closely related to South American isolates

Clinical Trials - Biocon sub, SCIREX Corp. to collaborate on global clinical trials

Clinical Trials - Clinical study of Aurora kinase inhibitor in hematologic cancers initiated

Clinical Trials - Decision making process in oncology needed improving

Clinical Trials - Novel Bayesian data analysis method facilitates trial monitoring

Clinical Trials - Pharmaceutical company announces Precise trial update

Clinical Trials - Recombinant human thrombin clinical trial results presented at meeting

Clinical Trials - Survey examines public perceptions of clinical research studies

Clinical Trials - U.S. FDA, research company sign protocol for trial of catheter-linked infections

Collaborations - Agreement creates ways for researchers to manipulate data

Collaborations - Agreement signed with Cytochemia to market Striant SR in Germany

Collaborations - Alliance focuses on metabolome analysis tools to speed disease, drug research

Collaborations - Clinical research software company and Galt Associates partner

Collaborations - Collaboration announced to advance infectious disease research

Collaborations - Collaboration with Cryptome Pharmaceuticals signed to validate cancer lead

Collaborations - Collaborative stem cell partnership announced in New Jersey

Collaborations - Company inks R&D collaboration with Tranzyme Pharma

Collaborations - Copromotion agreement signed with Mission Pharmacal

Collaborations - Deal signed to develop software products with Lucidyx

Collaborations - Deal struck to investigate asthma drug

Collaborations - Deal with Novartis signed for treatment of respiratory syncytial disease

Collaborations - Exclusive U.S. agreement made with Polyganics

Collaborations - Health benefits company, Missouri healthcare system commit to collaboration

Collaborations - Manufacturing agreement signed with Celltrion

Collaborations - Oncology company names Reddy's Laboratories to produce adjuvant

Collaborations - Partnership formed to increase access to certified clinical research associates

Collaborations - Pharma firm and Baylor to establish pediatric AIDS corps for Africa

Collaborations - Pharmaceutical companies announce collaboration in small molecule therapeutics

Colon Cancer - Antiproliferative action of water extracts from raspberry seeds analyzed

Complementary & Alternative Medicine - Benefits of phytoestrogens investigated in hormone replacement therapy

Complementary & Alternative Medicine - HPB-84 supplement to be manufactured by the Chemins Co.

Complementary & Alternative Medicine - New study reinforces safety of Chromax chromium picolinate

Complementary & Alternative Medicine - Unproved herbal products need separate regulation

Coronary Artery Bypass - Cardiopulmonary bypass linked to post-CABG aspirin resistance

Coronary Artery Disease - Lacidipine reduces common carotid artery IMT, decreases inflammatory markers

Coronary Artery Disease - Technical advances improve myocardial imaging in women

Coronary Heart Disease - Hormones found to play equivocal role in coronary heart disease

Corynebacterium Glutamicum - Ethambutol elicits L-glutamate efflux of Corynebacterium glutamicum

Crohn Disease -  Mycobacterium avium ssp. paratuberculosis may be implicated in Crohn disease

Crohn Disease - Phase 3 induction trial in Crohn disease therapy meets primary endpoint

Cryopreservation - Cryopreservation protocol developed to store 3-D bioartificial liver device

Cystic Fibrosis - Phase 1 study of PTC124 data presented at conference

Cytotoxicity Determination - Cytotoxicity determined without photochemical artifacts

Dengue Fever - El Nino influences synchronous dengue epidemics in Thailand

Dengue Virus - Lineage extinction/replacement in dengue 1 populations due to stochastic events

Depression - Report: Triple reuptake inhibitors to drive the antidepressant drug market

Depression Therapy - Optimal stimulus location and frequency for repetitive TMS determined

Dermatology - Insulin-like growth factor-I gene transfer speeds wound healing

Dermatology - New research in the area of dermatology detailed

Dermatology - Technology licensed to Avon for anti-aging skin care product

Diabetes Complications - Injected porcine collagen-derived matrix helps heal diabetic foot wounds

Diabetes Complications - Lidorestat is aldose reductase inhibitor for diabetes complications therapy

Diabetes Control - NDA for diabetes drug with pioglitazone HCL, glimepiride filed with U.S. FDA

Diabetes Research - Biosimulation company presents type 1 diabetes model and scientific insights

Diabetes Therapy - Crystal structure of 11 beta-hydroxysteroid dehydrogenase 1 reported

Diabetes Therapy - Findings advance knowledge in diabetes therapy research

Diabetes Therapy - L-arginine supplements improve T cell function in diabetic rats

Diabetes Therapy - Repaglinide reduces oxidative stress in tissues of diabetic rabbits

Diabetes Therapy - Rosiglitazone hepatotoxicity not greater in patients with high liver enzymes

Diabetes Therapy - Transforming growth factor-beta I gene therapy restores beta cell function

Diabetic Nephrology - Phase 3, phase 4 clinical program of therapy for diabetic nephropathy initiated

Diagnostics - Analytical techniques explore enzyme evolution factors

Diagnostics - Better non-invasive markers for chronic hepatitis C-related fibrosis are needed

Diagnostics - Company announces biomarker research collaboration with Bayer

Diagnostics - Company receives FDA approval for c-Kit pharmDx

Diagnostics - Findings in diagnostics provide new insights

Diagnostics - Model correction gives accurate assessments of brain tumor hemodynamics

Diagnostics - Newborn screening prevents brain damage caused by severe jaundice

Diagnostics - Novel approach to detect cancer measures fragments of host response proteins

Diagnostics - Report: Functional MRI enables noninvasive evaluation of epilepsy patients

Disease Associations -  Borrelia burgdorferi protein A analyzed, regulated expression revealed

Disease Associations - Carotid plaques examined, role of LDL humoral immune response defined

Disease Associations - Endocarditis studied, fibrinogen and fibronectin cooperative binding revealed

Disease Associations - SARS coronavirus examined, tissue immunohistochemistry defined

Drug Delivery - Development of Intraject sumatriptan advances with new trial data

Drug Delivery - European filing for aerosol inhaler version of AstraZeneca's Pulmicort announced

Drug Delivery - First patient receives TRT with Benephit Delta Infusion System

Drug Delivery - Modified liposomes carry photosensitizer to tumor vessels

Drug Delivery - Selective stabilized plasmid-lipid particles show longevity

Drug Development - Abstract presented on drug candidate for insomnia

Drug Development - Actos significantly improved components of diabetic dyslipidemia

Drug Development - Astex announces IND approval for novel cancer drug

Drug Development - Copaxone showed reduction in relapse rate among MS treatments

Drug Development - Method targets the true drug leads

Drug Development - Naglazyme for MPS VI launched in U.S.

Drug Development - Natural human alpha interferon approved for sale in Chile

Drug Development - Neuropathic pain drug enters phase I trial in Australia

Drug Development - New data presented for Zomig migraine treatment

Drug Development - New drug combinations may overcome hepatitis B virus drug resistance

Drug Development - Osteoporosis therapy receives positive opinion in Europe

Drug Development - Pharmaceutical company implements system into ion channel drug discovery program

Drug Development - Phase I data support further study of PamAb for Bacillus anthracis

Drug Development - Phase I trial to begin for Kogenate hemophilia product

Drug Development - Phase III study to evaluate first-in-class drug to treat cardiogenic shock

Drug Development - Positive data from TRX4 type 1 diabetes study reported

Drug Development - Propofol Injectable Emulsion, 1% launched

Drug Development - Research company receives honorary certificate from Jozef Stefan Institute

Drug Development - Results of Eculizumab extension trial in PNH reported

Drug Development - Study finds nasal spray to be effective treatment of nasal polyps and congestion

Drug Resistance - BLM helicase triggers leukemia cell resistance to cisplatin

Drug Resistance - Early detection system of drug resistance mutations in myeloid leukemia studied

Drug Resistance - Liposomal adriamycin targets new vessel growth within tumors

Drug Resistance - Proteasome inhibitors and TRAIL fight cancer cell chemoresistance

Drug Safety - Return of antidepressant to U.S. market welcomed by pharmaceuticals company

Drug Safety - Tacrolimus eye drops study halted, complaint filed against business partner

Drug Testing - Standardized Field Sobriety Tests detect marijuana intoxication

Elastic Fibers - Fibulin-5 examined, interaction with fibrillin and microfibrils revealed

Electronic Medical Records - Pinehurst Surgical to implement EMR solution

Embryonic Stem Cell Research - Embryonic SCs give rise to mature gonadotrope-like cells in embryoid bodies

Embryonic Stem Cell Research - Embryonic stem cell line expressing EGFP established

Embryonic Stem Cell Research - TGF-beta 2 enhances cardiac myocyte differentiation from embryonic stem cells

Endocrinology - Antisense oligonucleotides improve glucose and lipid levels in animal models

Endocrinology - Growth factor blockade cuts follicular thyroid cancer metastasis in mice

Endocrinology - Micro RNAs 15a and 16-1 influence pituitary adenoma growth

Endocrinology - Patients treated for chronic hepatitis C may develop thyroid dysfunction

Endocytosis - Glucagon-like peptide receptor studied, physiological roles clarified

Endocytosis - Macrophage mannose receptor studied, role as phagocytic receptor clarified

Endocytosis - Studies describe new findings in endocytosis research

Enterohemorrhagic Escherichia Coli - EC O157 acquired through indirect contact with farm environment

Environmental Ethics - Genetically modified insect vectors require examination

Environmental Health - Organochlorine levels in breast cancer adipose tissue measured

Environmental Health - Roundup and glyphosate have differential effects on human placental cells

Enzymology - Lysophosphatidic acid and sphingosine 1-phosphate void autotaxin expression

Enzymology - New findings in enzymology described

Enzymology - New tyrosine phosphorylation site in phospholipase-C-gamma-1 identified

Epicondylitis - Low dose shock wave therapy without local anesthesia is safe

Epilepsy - Recent findings in epilepsy provide new insights

Epilepsy - Report describes potential problem with new drug for seizures, pain

Epimmune Corp. - Vaccine maker to appeal NASDAQ delisting

Epstein-Barr Virus - Epstein-Barr virus latent protein examined, autoantigen response clarified

Erectile Dysfunction - ED drug amendment passage puts lives at risk, says prostate cancer organization

Escherichia Coli 0157:H7 Outbreak -  E. coli O157:H7 colitis outbreak associated with unpasteurized gouda cheese

Essential Tremor Therapy - Harmaline tremor animal model shows promise as preclinical drug screen

Eye Cancer - Cavitary changes in retinoblastoma related to better prognosis

Eye Health - Published paper shows thymosin beta 4 promotes corneal wound repair

Fibrinogen - Angiopoietin-1 variant discourages neovascular proliferation

Finance - Amex to trade options on pharmaceutical firm

Finance - Anti-infectives-focused research company secures funding, tests new compounds

Finance - Biotech company added to Russell 3000 index

Finance - Biotech company commences tender offer

Finance - Company pays promissory note due Elan

Finance - Company receives payment from Palatin Technologies

Finance - Diagnostics company reports new option grants

Finance - Drug development company closes equity financing, expands science advisory board

Finance - Equity firm invests in Tandem Labs; positions company for rapid growth

Finance - Maker of fine chemicals for healthcare products reports fiscal 2005 results

Finance - Ophthalmology company provides $1M grant for blindness prevention

Finance - Pharma company receives $5 million private placement

Finance - Pharma company signs offer for eight million shares of stock

Finance - Pharmaceutical company announces capital infusion from shareholders

Finance - Pharmaceutical company files shelf registration statement

Finance - Pharmaceutical firm announces concurrent public offerings of stock

Finance - Pharmaceutical firm begins trading on OTC Pink Sheets

Finance - Pharmaceutical firm raises $40.4M in private placement

Finance - Pharmaceutical firm receives notice from Amex

Fitness and Wellness - California statewide drive promotes active, healthy lifestyles

Gastric Cancer - Gastric cancer may originate from circulating bone marrow-derived stem cells

Gastroenterology - Hypoxia-inducible factor-1 pushes gastrointestinal stromal tumor progression

Gastroenterology - Secondary gene mutations make gastrointestinal tumors resist imatinib

Gastrointestinal Stroma Tumor - New research bolsters highly targeted gastro-intestinal cancer treatment

Gene Research - Gene studies reveal the complexity of mouse apolipoprotein B gene expression

Gene Research - Genetic modifiers define Gaucher disease phenotypes

Gene Transfer - Asialofetuin-labeled liposomes and the AFP promoter enhance transfection

Gene Transfer - New data illuminates research in gene transfer

Generic Drugs - Final approval received for Bupropion HCl

Generic Drugs - Generically creative: Drug companies balance patents and patients

Generic Drugs - Pharma company announces approval for Orange Ibuprofen Tablets

Generic Drugs - Pliva enters agreement to develop a controlled-release product

Generic Drugs - U.S. FDA accepts company's first two ANDAs

Generic Drugs - U.S. FDA grants tentative approval of generic oral blood-glucose-lowering drug

Genetics & Genomics - New 15-month policy study of risks and benefits of synthetic genomics set

Geriatric Cancer - Treatment practices for elderly cancer patients in Ontario, Canada, analyzed

Gliomas - CED drug delivery technique reviewed

Glucocorticoid Receptors - Glucocorticoid receptor examined, impaired nuclear translocation identified

Glycemic Control - Glipizide addition to metformin improves glycemic control in type 2 diabetes

Gonorrhea - Prolyliminopeptidase-negative N. gonorrhoeae strain circulating in Denmark

Grants - Canadian company awarded NSERC grant to develop cholesterol-lowering platform

Grants - Epilepsy therapy grants program recognizes 3 recipients of biannual review

Grants - First responders to Sept. 11 to receive medical, social work services

Grants - Philadelphia university receives $750,000 grant from pharmaceutical company

Grants - U.S. NIH grants awarded to 9 research centers for molecular libraries initiative

Guillain-Barre Syndrome - Companies collaborate in human trial for Guillain-Barre syndrome treatment

Gynecology - Capsaicin improves sexual relations

Gynecology - Combined abdominoperineal repair improves pouch-vaginal fistula outcome

Gynecology - Endometrial cancer patients respond to carboplatin and taxol

HIV/AIDS Coinfection -  Pneumocystis jirovecii genotypes vary in HIV-infected patients in Thailand

HIV/AIDS Coinfection - GB virus C prevalence lower in HIV-infected children than in coinfected adults

HIV/AIDS Coinfection - Routine syphilis screening increases detection in HIV-infected patients

HIV/AIDS Diagnosis - Laboratory methods to estimate HIV-1 incidence reviewed

HIV/AIDS Drug Use - Cocaine upregulates DC-SIGN expression on dendritic cells in HIV infection

HIV/AIDS HAART - Improvement of virologic response to HAART due to increased adherence

HIV/AIDS Healthcare - Satellite pharmacy at HIV clinic improves physician-pharmacist interaction

HIV/AIDS Mental Health - HIV-infected patients with history of mental trauma report greater physical pain

HIV/AIDS Pathogenesis - Codon volatility does not reflect selective pressure on HIV-1 genome

HIV/AIDS Pathogenesis - Findings advance knowledge in HIV/AIDS pathogenesis research

HIV/AIDS Pathogenesis - Functional genomic relationships HIV-1 disease revealed

HIV/AIDS Pathogenesis - PAR-2 induction by neuroinflammation prevents neural death during HIV infection

HIV/AIDS Pathogenesis - RNA helicase DDX1 involved in restricted HIV-1 Rev function in astrocytes

HIV/AIDS Pneumococcal Vaccine - HIV-infected children have poorer qualitative antibody responses to PnCV

HIV/AIDS Prevention - Branded advertising campaign increases condom use in Tanzania

HIV/AIDS Prevention - Some sexual history questions lacking in sexually transmitted infection clinics

HIV/AIDS Quality-of-Life - HIV-related neurological syndromes reduce health-related quality of life

HIV/AIDS Risk Factors - 2- to 3-fold risk increase of acquiring HIV-1 infection among persons with STDs

HIV/AIDS Therapy - New findings in the area of HIV/AIDS therapy described

HIV/AIDS Therapy - U.S. FDA approves new anti-HIV protease inhibitor for use in combination therapy

HIV/AIDS Transmission - DC-SIGNR is a cofactor in sexual HIV-1 transmission

HIV/AIDS Transmission - Greater prevalence of HIV infections heterosexually-acquired in the U.K.

HIV/AIDS Viremia - Low-level viremia not uncommon during very early period of primary HIV infection

HIV/AIDS-Related Hyperlipidemia - Atazanavir switch improves metabolic disorders in hyperlipidemic HIV patients

HIV/AIDS-Related Infection - HLA-DQB*0402/DRBI*08 risk factor for developing AIDS-toxoplasmic encephalitis

HIV/AIDS-Related Lipoatrophy - Resistin levels decrease after rosiglitazone in HIV patients with lipoatrophy

HIV/Tuberculosis Coinfection - T cell decrease in HIV/TB coinfection leads to marked cytokine reduction

Hantavirus - Researchers find novel peptides that inhibit entry by SNV and HTNV

Head and Neck Cancer - Genetic profiles classify oral squamous cell carcinomas

Head and Neck Cancer - RNA interference sensitizes oral cancer to chemotherapy

Healing - Wound closure modeled, acceleration after prior injury demonstrated

Healthcare Access - Human services nonprofit hosts policy summit on housing, healthcare for seniors

Healthcare Access - Weak, inequitable health systems block progress in Asia-Pacific, official says

Healthcare Coverage - Nevada insurance plan covers complementary and alternative treatments

Heart Failure - U.S. FDA approves BiDil for treatment of heart failure in black patients

Heart Organogenesis - Embryonic disturbance of cell adhesion molecules can result in cardiac defects

Heartburn - FDA accepts NDA for ZEGERID

Hematologic Disease - Phase I study of 506U78 for refractory hematologic malignancies conducted

Hematology - Recent studies add new data to hematology research

Hematopoiesis - Podocalyxin is CD34-related marker of HSCs and embryonic erythroid cells

Hematopoiesis - Researchers describe findings in hematopoiesis studies

Hemodialysis - Replacement of epoetin alfa with darbepoetin alfa safe, cost-effective

Hepatic Hydatidosis - Dual albendazole treatment effective for surgical patients

Hepatitis B - Pharma companies enter license agreement for Clevudine

Hepatitis B - Study shows effectiveness of hepatitis B treatment

Hepatitis B Diagnosis - New primers screen for hepatitis B virus variants

Hepatitis B Therapy - Extended lamivudine therapy delays hepatitis B-related liver disease

Hepatitis B Therapy - Reports advance knowledge in hepatitis b therapy research

Hepatitis B Therapy - Stabilized short interfering RNA cuts hepatitis B virus replication in mice

Hepatitis B Treatment - Data published evaluating long-term therapy with Hepsera for hepatitis B

Hepatitis B Vaccine - Non-invasive niosomes offer topical immunization against hepatitis B

Hepatitis B Vaccine Development - Hepatitis B vaccine protects animals against woodchuck hepatitis virus

Hepatitis C Epidemiology - Hepatitis C transmission prevails at an outpatient clinic in Japan

Hepatitis C Therapy - Clinical response varies in children vertically infected with hepatitis C

Hepatitis C Virus - Cells containing full-length hepatitis C replicons advance proteome studies

Hepatitis C Virus - Global factors regulate the response of hepatitis C to antivirals

Hodgkin Disease - SHIELD program officially launched

Hodgkin Lymphoma - Current treatment strategies of the German Hodgkin Study Group (GHSG) revealed

Hodgkin Lymphoma - Novel chemotherapies for Hodgkin lymphoma being investigated

Hormonal Therapy - Appropriate use of hormones reduces risk of comorbidities

Hormone Replacement Therapy - Estrogenic drugs raise PPE levels in striatum and nucleus accumbens

Hormones - Osteoblastic cells studied, influence of G11 alpha expression defined

Hormones - Studies describe new findings in hormones research

Human Papillomavirus - HPV 63 targets keratinocytes in or around eccrine ducts in plantar skin

Human Papillomavirus - HPV DNA methylation helps diagnose emergence of a population of tumor cells

Hunter Syndrome - Positive trial results of phase 3 enzyme therapy for Hunter syndrome reported

Huntington's Disease - Interrater agreement high in assessment of motor manifestations

Hyperactivity - Hyperactivity examined in mice, nature of orexin A induction clarified

Hypercholesterolemia - Berberine may be a useful alternative to statins for lowering cholesterol

Hypercholesterolemia - Statin therapy can briefly raise risk of psychiatric disturbances

Hypertension - New research in the area of hypertension detailed

Hypertension - Once-a-day diltiazem HCL is effective and safe against hypertension

Hypertension - Pharma company receives nonapprovable letter from U.S. FDA for PW2101

Hypertension - Salt intake studied, role in posttransplantation events clarified

Hypertriglyceridemia - Bezafibrate is effective in ameliorating atherogenic dyslipidemia

Imaging - European CHMP recommends granting marketing authorization for Vasovist

Imaging - Marketing authorization recommended for contrast agent, Vasovist

Imaging - Massachusetts hospital selects upgraded, dedicated breast MRI system

Infectious Disease - Texas expands state-mandated vaccines for children in child-care facilities

Inflammation - Lung inflammation analyzed, nature of chemokine induction clarified

Inflammatory Bowel Disease - IBD patients may receive less-than-optimal care

Inflammatory Bowel Disease - Preclinical data: NF-kappaB Decoy appears to reduce inflammation of IBD

Information Technology - Company launches single data management system

Information Technology - Gold Standard launches HIT services subsidiary

Information Technology - Handheld inventory management system launched

Information Technology - Internet application developer selected by PRA International

Information Technology - Le Centre Hospitalier Hotel Dieu du Creusot deploys remote access solution

Information Technology - New version of software tool simplifies selection of SNP assays

Information Technology - Oregon hospital selects pharmacy robotic technology

Information Technology - Preconfigured compliance solution for entry level pharma firms introduced

Information Technology - ProEthic Pharmaceuticals selects enterprise contract management provider

Information Technology - Software company awarded American Hospital Association endorsement

Information Technology - Technology company unveils unified platform for clinical data management

Information Technology - Technology solution fully deployed at Partners HealthCare

Intracerebral Hemorrhage - Granulocyte colony-stimulating factor promotes sensorimotor recovery

Intraperitoneal Chemotherapy - Insertion of intraperitoneal port for chemotherapy detailed

Ischemia - Hyperoxygenation may be critical triggering factor for postischemic remodeling

Kidney Function - Glomerular filtration examined, involvement of perlecan clarified

Kidney Transplantation - Impact of gastric acid suppressants on tacrolimus bioavailability determined

Laminin - Role of laminin in tumor progression discussed

Lamivudine - Combination therapy surpasses monotherapy in chronic hepatitis B patients

Laparoscopic Surgery - Utility of post-discharge thromboprophylaxis evaluated

Legal Issues - Company files request to withdraw motion for injunction against Insmed, Celtrix

Legal Issues - Eli Lilly & Co. to pay $700 million in product liability group settlement

Leukemia - Researchers publish new studies and findings in the area of leukemia

Lipolysis - Sympathetic modulation by carvedilol and losartan reduces lipolysis

Liver Cancer - Angiostatic therapy hinders hepatocellular carcinoma progression

Liver Cancer - Liver cancer therapy achieves primary endpoint in phase 2a clinical trials

Liver Cancer - The hepaCAM gene is silenced in human hepatocellular carcinoma

Liver Transplantation - Alcohol compounds the risk of hepatitis-C-related liver cancer formation

Lung Cancer - Chemotherapy induced expression of cyclooxygenase-2 in lung cancer

Lung Cancer - Positive recommendation in European Union of lung cancer medicine erlotinib

Malaria - Fatty meals have no effect on the relative oral bioavailability of piperaquine

Malaria Diagnosis - Clinical malaria under transmission conditions in Kenya defined

Marijuana Use - Acute THC exposure augments quinpirole-induced hyperlocomotion

Market Analysis - Biotech companies focusing increasingly on in-licensing

Market Analysis - Biotech companies have to insure against failures in R&D

Market Analysis - Boston, San Francisco, Philadelphia are top life sciences clusters

Market Analysis - Enbrel leads the market for biologic therapies for arthritis, psoriasis

Marketing - First major sales campaign for HairMagic begins

Matrix Metalloproteinase - Epilysin expression studied, effect of compression in scars revealed

Measles Vaccine - Ability of measles protein to regulate genome replication examined

Measles Vaccine - Measles control is possible in areas of widespread HIV infection

Medical Devices - Portable daily hemodialysis device receives U.S. FDA clearance

Medical Devices - Prosthetic arm with thought-controlled movement introduced by rehab developer

Medical Errors - Machine dispenses peace of mind in a flash of light

Medicare - Medicare Part D prescription drug benefit agreement announced

Melanoma - Differential effects of selenite and selenate delineated

Melanoma - Protein amplification in melanoma is possible drug target

Melanoma - Scientists ID gene driving melanoma cell growth and survival

Meningitis - Vaccination virtually eliminates Hib meningitis in The Gambia

Mental Health - Drugs and therapy prevent interferon-induced depression in high-risk patients

Mental Health - Pharma companies achieve milestone in Asenapine development collaboration

Mental Health - U of Pennsylvania researcher finds teen mental health declining in U.S.

Mental Illness - End-of-life treatment preferences of persons with mental illness discussed

Mergers & Acquisitions - Food and animal safety company to acquire UCB's dairy antibiotic testing

Mergers & Acquisitions - Genetic and protein analysis company to acquire Nextal Biotechnologies

Mergers & Acquisitions - Heumann Pharma Generics of Germany acquired by Torrent Pharma GmbH

Mergers & Acquisitions - Microscience, a U.K.-based vaccine company, acquired

Mergers & Acquisitions - Pharma company expects sale of biologics manufacturing business to close soon

Mergers & Acquisitions - Pharma company purchases Sinopharm Medicine holding Tianjin

Mergers & Acquisitions - Pharma company to acquire InKine Pharmaceutical Company

Mergers & Acquisitions - Rice bran company signs letter of intent with Food Trading Dominicana

Mergers & Acquisitions - Shareholders endorse Iliad acquisition and capital raising

Metabolic Disease - ABCD4 and BG1 gene expression correlate with adrenoleukodystrophy pathology

Metabolic Syndrome - New findings in the area of metabolic syndrome described

Metabolic Syndrome - Strategies for managing metabolic syndrome reviewed

Methicillin-Resistant Staphylococcus Aureus - Screening program helps prevent hospital-acquired MRSA infections

Methicillin-Resistant Staphylococcus Aureus - Sequence types 8 and 80 predominate community-acquired MRSA in Norway

Migraine - Frovatriptan well-tolerated when used as 6-day dosing regimen for MRM

Migraine - Research shows new Imitrex tablets absorbed faster

Migraine Headaches - New campaign to help migraine sufferers find pain relief

Mosquito-Borne Disease - Ferritin light-chain homologue promoter in Aedes aegypti mapped

Mosquito-Borne Disease - Foreign protein secreted in transgenic mosquitoes

Multiple Organ Failure - N-acetylcysteine treatment has no prophylactic use

Multiple Sclerosis - IND submitted to U.S. FDA for oral treatment of relapsing multiple sclerosis

Multiple Sclerosis - Trial of vaccine for MS demonstrates increase in gene marker to track T-cells

Multipotent Stem Cells - Multipotent stem cells isolated from adult olfactory mucosa

Mycobacterium Avium -  M. avium isolation method from milk tank improved

Mycobacterium Avium - Real-time PCR detects M. avium subsp paratuberculosis in water & milk

Mycobacterium Tuberculosis -  M. tuberculosis PDT is monofunctional and nonfusion protein

Mycobacterium Tuberculosis -  Mycobacterium tuberculosis strains possess functional cellulases

Mycobacterium Tuberculosis - ESAT-6 may contribute to macrophage activation in tuberculosis

Mycobacterium Tuberculosis - ESAT-6/CFP-10 fusion protein and peptides used for optimal MTB diagnosis

Mycobacterium Tuberculosis - GTP-binding/synergy loop domain mutations of MTB ftsZ compromise its function

Mycobacterium Tuberculosis - IdeR binding sites in sequences of all M. tuberculosis ORFs identified

Mycobacterium Tuberculosis - Monoacylated MDP confers TLR2/TLR4 activation on dendritic cells

Myocardial Infarction - Adenosine, at a particular dose, may help patients with STEMI

Myocardial Infarction - Antidepressants may lower risk of recurrent heart attack, death

Myocardial Infarction - Aspirin underprescribed to prevent heart attack and stroke

Myocardial Infarction - Nitroprusside is an effective treatment of no-reflow phenomenon

Neural Stem Cell Research - Enriched environment increases neurogenesis in subventricular zone after stroke

Neural Stem Cell Transplantation - Lineage-restricted neural SCs differentiate after transplant to injured spine

Neurodegenerative Diseases - Glycosaminoglycans have therapeutic potential

Neurology - Brain structures analyzed, nuclear condensation of binding protein shown

Neurology - Neuropeptide B examined, central nervous system immunoreactivity defined

Neuroscience - Albumin enhances MCP-1 output from rat embryonic mixed brain cells

Neuroscience - Brain injury center awards clinical study for TBI trial data capture services

Neuroscience - CD147 regulates protein complexes linked to Alzheimer disease

Neuroscience - Developing murine neural tubes rely on sonic hedgehog for angiogenesis

Neuroscience - Ischemic brain injury examined, neuroprotective effects detailed

Neuroscience - Neuroendocrine effects of salsolinol characterized in lactating rats

Neuroscience - Study confirms value of childhood epilepsy test

Neuroscience - Tmhs gene mutations disrupt hair bundle morphogenesis

Non-Hodgkin Lymphoma - HUMAX-CD20 induces clinical response in NHL at all dose levels, company reports

Norovirus Transmission - Person-to-person spread the most important norovirus transmission route

Nosocomial Infections - Digestive endoscopy transmits hepatitis C infection infrequently

Nosocomial Infections - Endoscope channels harbor hepatitis B virus DNA after on-site cleaning

Obesity Therapy - Endocannabinoid modulation of lipogenesis may promote weight loss

Obesity Therapy - Reports describe recent advances in obesity therapy research

Obstetrics - Immunological status influences hepatitis E severity in pregnant women

Obstetrics - Interleukin-6 may elevate fetal nucleated red blood cells

Obstetrics - Safety of oxcarbazepine investigated

Obstructive Sleep Apnea - Pharma companies collaborate to develop therapy for obstructive sleep apnea

Oncogenesis - Studies advance knowledge in oncogenesis research

Oncology - Downregulated BRCA2 expression upregulates prostate cancer cell proliferation

Oncology - Effectiveness of combined therapeutic modalities investigated in cervical cancer

Oncology - Findings describe new data in oncology research

Oncology - Interleukin 6 supports p53 tumor suppressor gene promoter methylation

Oncology - Interleukin-8 levels rise in advanced prostate cancer

Oncology - MAGE-D1 inhibition may contribute to breast cancer formation

Oncology - Recombinant CXC chemokine ligand 10 boosts the potency of cisplatin

Oncology - The neural phenotype of Ewing family tumors is linked to EWS-FLI1

Ophthalmology - Conjunctival tissues do not model VEGF expression in pterygia

Opthalmology - Opthalmology company receives CE Mark approval for laser vision treatment

Oral Cancer - Cytotoxicity of phenolic acid phenethyl esters on oral cancer cells evaluated

Orthodontics - Researchers test drug that could cut treatment time in half

Orthopedics - Stem cells and cytokines spur bone growth in experimental models

Outbreaks - Coccidioidomycosis epidemic associated with climatic changes

Pain Management - Pharma compoany files investigational new drug application for pain treatment

Pain Management - Preliminary results announced from study of postoperative pain relief product

Pain Medicine - Children in chronic pain need better support

Pain Medicine - Constipation a serious problem for cancer patients treated with opioids

Pancreatic Cancer - Inositol hexaphosphate proposed as novel treatment for pancreatic cancer

Parkinson Disease - "Fast tapping" test not suitable for clinical assessment

Parkinson Disease - Drug therapy for Parkinson disease available in U.K., European launches planned

Parkinson Disease - Low-dose pergolide provides limited benefits in de novo disease

Parkinson Disease Therapy - Frequent L-dopa dosing plus entacapone effective in animals

Patents - Biopharmaceutical company announces patent on amyloid lowering drugs

Patents - Drug-delivery company gets Mexican patent

Patents - U.S. patent allowed for novel cancer drug in clinical development

Pediatric Allergy Medicine - Impact of facemask design on spacer drug delivery determined

Pediatric Epilepsy - U.S. FDA approves Keppra for use in childhood epilepsy

Pediatric Epilepsy Therapy - Potentially dangerous coprescription practices found in Scotland

Pediatric Nephrotic Syndrome - Mycophenolate mofetil recommended in place of cyclosporine A

Pediatric Oncology - Pediatric and adult leukemia cells bear distinctly different properties

Pediatric Pain Management - Use of NSAIDs carries risk of adverse reactions in children

Percutaneous Coronary Intervention - Enoxaparin shows similar results as unfractionated heparin during PCIs

Percutaneous Coronary Intervention - Plasma PAI-1 levels may identify patients with late restenosis risk

Personnel - Biomedical company adds two VPs to executive management

Personnel - Biopharmaceutical company announces new president and chief executive officer

Personnel - Biopharmaceutical company announces senior vice president of human resources

Personnel - Biopharmaceutical company names vice president of investor relations

Personnel - Biotech company expands senior scientific team into California

Personnel - Biotech group appoints chair of its new industrial, environmental section

Personnel - Biotech names VPs in product operations, regulatory, and research

Personnel - Cancer therapeutics development company appoints senior vice president

Personnel - Clive V. Bennett appointed president and COO of MOVA Pharmaceutical

Personnel - Dr. Abraham Sartani appointed to pharma's board

Personnel - Dr. Craig Smith joins board of immunotherapy company

Personnel - Dr. Leslie Hudson to become CEO and president of pharmaceutical company

Personnel - Dr. Paul A. Marks named chairman of scientific advisory board

Personnel - Drug development company names executive director

Personnel - Eric Reimer named chief growth officer by behavioral health management company

Personnel - Healthcare company names executive vice president, chief medical officer

Personnel - Leslie Stiles named honorary chair of Pennsylvania breast cancer group

Personnel - Martin Freed, MD, appointed chief medical officer by pharmaceutical company

Personnel - Medical director of NICU named at San Jose's Good Samaritan Hospital

Personnel - Medical services company names vice president and general manager

Personnel - Molecular diagnostic technology company announces new leadership team

Personnel - Nancy Oaks appointed VP of sales U.S. Rx division by pharmaceutical company

Personnel - Oncology center company appoints member to board of directors

Personnel - Pharma company announces key appointments

Personnel - Pharma company hires Sr. VP and general counsel, announces promotion

Personnel - Pharmaceutical company announces personnel changes

Personnel - Pharmaceutical company founder James A. Wells, PhD, joins UCSF faculty

Personnel - Pharmaceutical company's chief operating officer elected chair of medical group

Personnel - Therapeutic apheresis services company appoints president and COO, CEO

Personnel - Thomas H. McLain appointed to Biotechnology Industry Organization's board

Pharmaceutical Research - Consultancy releases study on pharma industry

Pharmaceutical Research - New report examines cough, cold, allergy, and sinus market

Pharmaceutical Research - Research study examines recruitment and retention at pharma companies

Pharmaceutical Research - Study examines pharma product commercialization

Pharmaceutical Research - Survey examines consumer use of online resources

Plague - Functions of differentially expressed proteins ID'd for Yersinia species

Platelets - Reports add new data to platelets research

Pneumococcus - Pneumococcal pathogenesis examined, teichoic acid esterase crystallized

Polio - Identifying dominant mutations of poliovirus genome could lead to new therapies

Polio Diagnosis - Determination of poliovirus-specific IgA in saliva by ELISA tests

Postural Tachycardia Syndrome - Acute acetylcholinesterase inhibition improves tachycardia in POTS

Prions - Antiprion drugs assessed, use of high-throughput screening described

Prions - Research add new data to prions body of knowledge

Product Licensing - Jilin Natural Pharmatech Group licenses DiAoNing

Product Licensing - Late-stage anticancer compound acquired from Sumitomo Pharmaceuticals

Professional Education - Medical training facility opens in Columbus, Ohio

Professional Education - Provider of testing services, nuclear cardiology certification board join forces

Prostate Cancer - A20 gene expression regulated by TNF, Vitamin D, and androgen in prostate cancer

Prostate Cancer - Androgen deprivation therapy associated with fracture risk in prostate cancer

Prostate Cancer - Co-cultured cells exhibit bidirectional activity

Prostate Cancer - No serological evidence of association between prostate cancer and HSV2/HSV8

Prostate Cancer - Regulatory filing process for European approvals of prostate cancer drug begun

Proteomics - Activated protein C promotes wound healing by stimulating angiogenesis

Proteomics - Prolonged p38 activity produces endothelial cell dysfunction

Proteomics - Protein signatures emerge in hepatocellular carcinoma samples

Proteomics - Repressed p53 delays new vessel maturation

Proteomics - Tumor endothelial marker 7 is a transmembrane receptor in vertebrate brains

Pulmonary Medicine - Epidural block - isoflurane/nitrous oxide combo okay for lung resection

Pulmonary Medicine - New findings in the area of pulmonary medicine detailed

RNA Research - Preliminary microRNA expression in mouse stem cells presented at conference

Receptors - Glucocorticoid receptor examined, nature of regulation defined

Recombinant Technology - Bacteria manufacture protein suitable for medical adhesive use

Reconstructive Surgery - Extracorporal shock waves surpass gene therapy for revitalizing skin flaps

Renal Cell Cancer - Echo contrast-enhanced ultrasound assesses renal cell carcinoma angiogenesis

Renal Graft - Tacrolimus improves serum lipid levels and improves cardiovascular risk

Renal Transplantation - BP, arterial wall properties altered after cyclosporine to tacrolimus switch

Renal Transplantation - Cytokine polymorphisms did not influence rejection in renal transplantation

Respiratory Medicine - Promising phase II data with inhaled anticholinergic LAS34273 reported

Restenosis - Recent findings in restenosis provide new insights

Restless Leg Syndrome - New pramipexole data for restless leg syndrome presented at conference

Retinopathy - Angiopoietin 1 prevents but does not reverse retinal neovascularization

Rheumatoid Arthritis - Rituximab appears to be a safe and effective targeted therapy for RA

SARS Coronavirus - Researchers report details of new studies and findings in the area of SARS coronavirus

Saphenous Vein Grafts - Clinical outcomes after sirolimus-eluting stent implantation are good

Schistosomiasis - Ten million Africans treated by international disease treatment program

Schizophrenia Therapy - Clinicians overestimate antipsychotic treatment adherence

Sexual & Reproductive Health - Company opens new Center for Collaborative Reproduction

Sexual & Reproductive Health - Pharma company asserts no increased risk of blindness with Viagra

Sexual & Reproductive Medicine - In vitro organotypic model of human endometrium developed

Sexually Transmitted Infection - High herpes simplex virus-2 and syphilis seroprevalence among female drug users

Sickle Cell Anemia Therapy - Efficacy of procaine in treatment elucidated

Smooth Muscles - Airway smooth muscle cells studied, nature of CXCL-8 induction clarified

Sodium Channel - Ras examined, role in Na+ channel coupling defined

Sports Medicine - Pamidronate shows promise as adjunct treatment for stress fractures

Staphylococcus Aureus -  S. aureus cysteine proteinases studied, role in vascular leakage defined

Stem Cell Policy - Diabetes group urges Senate action on stem cell research legislation

Stem Cell Policy - Subcommittee approves stem cell policy enhancements

Stem Cell Research - BRCA2 deficiency in small intestine leads to spontaneous stem cell deletion

Stem Cell Research - Company provides update on hESC at stem-cell meeting

Stem Cell Research - EDNRB or KIT signaling needed for maintenance/survival of melanocyte precursors

Stem Cell Research - GCSF & GMCSF have differential effects on neutrophil survival and function

Stem Cell Research - Molecular markers distinguish bone marrow mesenchymal SCs from fibroblasts

Stem Cell Research - Neural stem cells isolated from postnatal cerebellum

Stem Cell Research - Neurturin augments non-neuronal cell numbers via increased cell proliferation

Stem Cell Research - Peripheral blood cell fractions spawn endothelial progenitor cells

Stem Cell Research - Study finds adult stem cells show same ability to self-renew as embryonic

Stem Cell Research - Study: Cell nuclear transfer in old animals generates youthful immune cells

Stem Cell Research - Zac1 expressed in stem cells of neuroectoderm and mesoderm during embryogenesis

Stem Cell Transplantation - Cultured BM cells can act as substitute for autograft or BMP in spine fusion

Stem Cell Transplantation - IL-6/TNF-alpha polymorphisms identifies risk of unsuccessful limbic SC graft

Streptococcus Pyogenes - Different strains may circulate simultaneously during S. pyogenes outbreak

Stress - Human lens studied, role of reductases in oxidative stress resistance revealed

Stroke - Nerve protector could make for new stroke treatments

Stroke - U.S. FDA grants clearance to market blood test for assessing risk of stroke

Strokes - Cerebral endothelial ICAM-1 expression analyzed, aprotinin effect shown

Surgical Technology - Post-surgical adhesions therapy data presented at conference

Synapsin - Synapsin examined, nature of cyclophilin association defined

Thymic Cancers - Results of multimodality treatments revealed

Tissue Engineering - Researchers' data advance tissue engineering research

Tissue Engineering - Respiratory epithelial cells may be used for tracheal tissue engineering

Tissue Engineering - Rotary culture enhances preosteoblast aggregation and mineralization

Tissue Engineering - Tissue-engineered artificial bile duct resembles native bile duct

Tissue Engineering - Umbilical vein scaffold developed for cardiovascular tissue engineering

Tobacco Use - Alcohol augments cognitive biases for smoking cues

Tobacco Use - NicoDerm CQ gives "the Patch" a makeover

Transplant Medicine - Basiliximab may reduce incidence of acute organ rejection in lung transplants

Transplant Medicine - Immunosuppressive drugs remain vital years after liver transplantation

Transplant Medicine - New findings in transplant medicine described

Transplant Medicine - Repeated pulse therapy increases graft loss in HCV-positive liver recipients

Transplant Medicine - Select therapies limit fibrosis progression after liver transplantation

Tuberculosis - Antimycobacterial therapy associated with shift toward predominant Th1 phenotype

Tuberculosis - Biochemical changes associated with antituberculosis drugs

Tuberculosis - Cattle movements predict bovine tuberculosis occurrence in Great Britain

Tuberculosis - Tuberculosis diagnosis confirmed by PCR in prehistoric skeleton in Britain

Tuberculosis Diagnosis - Sensitivity of assays for detecting tuberculosis compared

Tumor Suppressor - ING4 functioned as tumor suppressor

Turner Syndrome - Effect on growth hormone therapy on adult height determined

Type 1 Diabetes - Therapy with TRX4 preserves the function of insulin-producing beta cells

Type 2 Diabetes - Type 2 diabetes supplement HPB-84 study results reported

Tyrosine Kinase - Na+, K+-ATPase examined, novel regulation in cortical neurons revealed

Umbilical Cord Blood Banking - Red blood cell depletion systems compared for cell recovery and RBC reduction

Vaccine Development - Encouraging the development of new vaccines described

Vaccine Development - Factors affecting manufacturers' decisions to produce vaccines reported

Vaccines Development - Recent findings illuminate research in vaccines development

Vancomycin-Resistant Enterococcus Faecium - Esp gene detected in all vancomycin-resistant E. faecium strains in Korea

Vascular Anomalies - Urine test may help monitor disfiguring birthmarks

Vector Development - Studies advance knowledge in vector development research

Venous Ulcers - Final version of OrCel study protocol submitted to U.S.FDA

Virology - Alcohol impedes hepatitis C response to therapy in HIV-coinfected patients

Virology - Researchers' findings advance virology research

Virology - Virus-encoded inhibitor blocks RNA interference

Wound Healing - Microvascular perfusion improves when murine wounds are exposed to hyperoxia

Yersinia Pestis - pgm locus plays role in Yersinia pestis adaptation to its environment

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