Drug Week
Susan Hasty, Publisher
Table of Contents . . . August 12th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Acne - Company announces results from phase II study of zileuton in acne patients
Cancer Therapy - Pancreatic cancer trial opens using tumor-targeted gene therapy vector
Cancer Therapy - Patient enrollment begins for phase I/II trial of Amplimexon plus dacarbazine
Drug Development - Phase II trial of pagoclone initiated for stuttering
Drug Development - Product promotes healing in venous stasis ulcers
Hemophilus ducreyi - H. ducreyi dsrA mutant killed by normal human serum initiated by IgM binding
Addiction Medicine - Cannabinoid antagonist SR 141716A prevents heroin relapse in rats
Adrenoleukodystrophy - Study shows Lorenzo's Oil prevents onset of pediatric neurological disorder
Adverse Drug Reactions - Etanercept therapy for rheumatoid arthritis evaluated over 4 years
Adverse Drug Reactions - Importance of reporting suspected adverse drug reactions emphasized
Adverse Drug Reactions - Study reveals consumers willing to take medication with risks similar to Vioxx
Age-Related Macular Degeneration - Pharma companies collaborate to evaluate compounds for ocular disease
Age-Related Macular Degeneration - Pharma company announces clinical program evaluating VEGF Trap
Aging - Aging of liver studied, modulation of apolipoprotein and interleukin beta shown
Alcoholism - Ondansetron safe and effective for adolescent use
Aldosterone - Aldosterone produced in the adrenals is main source of cardiac aldosterone
Allergies - Sublingual immunotherapy proven effective for administering allergy medicine
Allergy & Immunology - Company announces rapid, expanded enrollment in ragweed allergy pediatric trial
Allergy & Immunology - Maternal allergy is found to influence allergic response of neonate
Allergy & Immunology - New pan-European surveillance system for inhalant allergies launched
Allergy & Immunology - Pediatric allergies-focused company acquires rights to Twinject for anaphylaxis
Alternative Medicine - Alternative approach to neurolysis is successful in blocking pelvic pain
Alternative Medicine - Study investigates effectiveness of moxibustion in breech presentation
Alzheimer Disease - Company to continue clinical development of neramexane
Alzheimer Disease - Initiation of phase Ib PRX-03140 clinical trial initiated
Alzheimer Disease - Novel neurotrophic agent shows promise for treatment
Alzheimer Disease - Pharma company receives U.S. and European approval for Alzheimer diagnostic test
Alzheimer Disease - Roche and imaging company collaborate on personalized care for Alzheimer disease
Analgesia - Endomorphin-2 analogues analyzed, structure-activity relationships revealed
Anesthesia - Regional cerebral oximetry correlates with invasive SvO2 measures
Aneurysm - Dor procedure is reproducible option for treating postinfarction LV aneurysm
Angiology - Angiopoietin uses tyrosine kinase receptor to foster lymphangiogenesis
Angiology - Irradiated tumor vessels are susceptible to VEGF receptor inhibitor
Angiology - Platelet count increased in older, poor-risk patients with valproic acid
Animal Models - Nonhuman primates are models for hematology, immunology, and virology studies
Anti-Inflammatory Treatments - P38 MAPK inhibitor reduces inflammatory endothelial cell activity
Anticancer Therapy - Local IL-2 therapy most effective against cancer when injected intratumorally
Antimicrobial Therapy - Activity of beta-lactams against intraphagocytic infection compared
Antimicrobials - Antimicrobial peptide pheromone analyzed, structure and mode of action revealed
Antimycobacterial Drug Development - Oxadiazolone derivatives have antimycobacterial activity
Antivirals - Oyster hemolymph analyzed, putative antiviral activity identified
Apoptosis - Chronic lymphocytic leukemic cells exhibited apoptotic signaling via TRAIL-R1
Apoptosis - Novel small molecule induced apoptosis in A549 human lung cancer cells
Arthritis - Company launches Pennsaid Plus
Arthritis - Early rheumatoid arthritis studied, reduced loss of hand bone density reported
Arthritis - Study emphasizes importance of bone loss in rheumatoid arthritis
Aspergillosis Therapy - Voriconazole less expensive than amphotericin B for aspergillosis
Asthma - Bronchial muscle contraction analyzed, CPI-17 involvement in asthma indicated
Asthma - Lymphopoietin expression studied, role in asthmatic airways clarified
Atherosclerosis - Azithromycin doesn't slow progression in C. pneumoniae-infected mice
Atherosclerosis - Lilly pays $1.6 million with initiation of phase 2 trial on athersclerosis drug
Atherosclerosis - Study examined effects of CYP7A1A-278C promoter polymorphism in atherosclerosis
Atopic Dermatitis - Tacrolimus and azoles have synergistic anti-Malassezia effects
Avian Influenza - International health entity stresses threat from Avian influenza has not ebbed
Awards - Virus research funded at Robarts by U.S.-based Howard Hughes Medical Institute
Benign Prostatic Hyperplasia - BPH patients improve more rapidly with tamsulosin hydrochloride, study shows
Beta Agonists - Beta-agonist treatment impairs cardiac function more in adults than in aged rats
Bioterrorism - Groups work to develop vaccine to reduce effects of ricin toxin
Bipolar Disorder - High-density whole genome association study of biopolar disorder announced
Bladder Cancer - Bladder cancer test receives marketing approval in Japan
Breast Cancer - Antibody-endostatin fusion protein localizes to breast tumors in mice
Breast Cancer - Breast cancer treatment Arimidex granted new indication for postmenopausal women
Breast Cancer - Company forms alliance with Y-ME National Breast Cancer Organization
Breast Cancer - Feasibility of alpha-emitting radium-223 in skeletal metastases therapy examined
Breast Cancer - Heat shock protein 90 inhibitor potentiates breast cancer cell bone metastasis
Breast Cancer - Improved screening of minority women can help prevent breast cancer
Breast Cancer - Marketing authorization applications submitted for Femara in U.S. and Europe
Breast Cancer - Promising antitumor agents found to be effective in reducing effects of estrogen
Breast Cancer - Researchers suggest that genetic polymorphisms may increase breast cancer risk
Breast Cancer - Socioeconomic disparities influence breast cancer survival
Breast Cancer - Study investigates concordance of bilateral breast cancers in BRCA carriers
Breast Cancer Therapy - Molecular basis for melatonin's oncostatic effects determined
Brucella - Brucella virulence factor required for intracellular survival
Business & Finance - Biopharma company announced financial results
Business & Finance - Biopharmaceutical company joins new Russell Microcap Index
Business & Finance - Home respiratory care company reports financial results
Business & Finance - Letter of intent signed for subscription to 7.5M shares of biotech company
Business & Finance - Oncology-focused biopharmaceutical company reports second quarter results
Business & Finance - Pharma company reports second quarter 2005 financial results
Business & Finance - Pharma firm announces conversion of all outstanding shares of series A stock
Business & Finance - Pharmaceutical company announces preliminary earnings per share
Business & Finance - Pharmaceutical company eliminates 2009 debt, elects to auto-convert notes
Business & Finance - Pharmacy benefit manager comments on outlook for fiscal 2006
Business Update - Ablatherm maker reports continued progress in European marketing
Business Update - Acquisition of TRISENOX from Cell Therapeutics complete
Business Update - Biochemical company announces new organization comprising 4 business units
Business Update - Biotech company to develop diagnostic tools for early detection of disease
Business Update - Cancer-focused company announces plan to explore strategic alternatives
Business Update - China-focused, Canada-based pharma names auditor, eyes AMEX
Business Update - Clinical research organization opens new facility
Business Update - Company expands trials of hair restoration pills
Business Update - Company to seek VA contracts for pharmacy robotic technology
Business Update - DNAPrint genomics upgrades genotyping platform
Business Update - Drug development company updates global business development program
Business Update - Drug store signs agreement with Take Care Health Systems
Business Update - Dynamic metabolic phenotyping services company opens new laboratory
Business Update - First manufacturing project of antibody using gene expression technology done
Business Update - Food and health natural source ingredients company opens new facilitiy
Business Update - Health plan selects location for mail service pharmacy
Business Update - Health products company to purchase some OTC assets of pharmaceutical company
Business Update - Invitrogen sub announces increased assay flexibility
Business Update - J&J company to acquire nesiritide rights in Europe from GlaxoSmithKline
Business Update - Milestone payment issued from Merck for MedPulser DNA delivery system
Business Update - Pharma company expands sales team, focuses on gastroenterology
Business Update - Pharma company sells Axid Oral Solution to Braintree Laboratories
Business Update - Pharma firm joins new Russell Microcap Index
Business Update - Pharmaceutical companies build portfolios by making strategic deals, report says
Business Update - Pharmacy benefit management introduces new logo
Business Update - Report examines effects of generic competition in neuropathic pain market
Business Update - Sales and marketing services provider introduces new solution
Business Update - Varibar Thin Honey launched for study of swallowing disorders
Business Update - Veterinary pet insurance companies name reasons pets taken to vet
Business Update - Zostrix brand acquired
Business Update - sanofi pasteur exercises option on bacterial vaccine antigens
CNS Lymphoma - Necrotizing vasculopathy diagnosed in primary CNS lymphoma
Cancer Diagnostics - 2-[C-11]thymidine positron emission tomography reproducibility tested
Cancer Research - Cancer research center receives $30 million gift
Cancer Therapy - Acetyl-L-carnitine attenuates chemotherapy-induced peripheral neuropathy
Cancer Therapy - Angiozyme stabilizes disease in patients with refractory cancer
Cancer Therapy - Artificial glioma tumor suitable for NMR spectroscopic study
Cancer Therapy - DNA adopts a new fold
Cancer Therapy - Low-dose chemotherapy regimens mitigate adverse clotting events
Cancer Therapy - Results reported from phase I trial with Lewis Y antibody IGN311
Cancer Therapy - Scientists to mimic nature for newest cancer drugs
Cancer Treatment - Interdisciplinary approach to treating prostate cancer described
Cancer Treatment - Novel intrahepatic arterial chemotherapy introduced for hepatocellular carcinoma
Carcinogenesis - Compounds that inhibit growth of PhIP-resistant cancer cells identified
Cardiology - Cardiologists will convene to explore breakthroughs in cardiac imaging
Cardiology - Erythropoietin forecasts patient outcomes after congestive heart failure
Cardiology - Nexvas program expanded into acute coronary market
Cardiology - Osteoprotegerin encourages the progression of abdominal aortic aneurysm
Cardioprotection - Cardiac GCA prevents cardiac remodeling by inhibiting calcineurin-NFAT pathway
Cardioprotection - Tocotrienol may inhibit c-Src activation and proteasome stabilization
Cardiovascular Disease - Enabling patients may lead to CV improvement in African-American populations
Cardiovascular Mortality - Reduced FEV1 is marker for CV mortality independent of age, gender, and smoking
Cell Biology - Daxx is essential for stress-induced cell death
Chemistry - Microreactor efficiently regenerates cofactors for biocatalysis
Chlamydia Trachomatis - Azithromycin treatment significantly reduces pelvic inflammation
Chronic Kidney Disease - Increased TPR is major contributor to elevated BP in children with CKD
Chronic Liver Disease - Liver iron overload in alcoholic end-stage liver disease affects other organs
Chronic Low Back Pain - Effect of transdermal fentanyl system on quality of life evaluated
Cirrhosis Therapy - Aminoguanidine reduces vascular NO output and liver damage in rats
Clinical Trials - Ghrelin agonist shows selectivity profile in treating gastrointestinal disorders
Clinical Trials - Positive results in phase 1 trial of neuro-inflammatory drug candidate reported
Clinical Trials - Report: Clinical trial registries may diminish medical publications' impact
Clinical Trials - SPA process completed for paclitaxel formulation clinical trial in breast cancer
Clinical Trials - Study results of anti-inflammatory agent for COPD, asthma reported
Coccidioidomycosis - Precipitation influences incidence of coccidioidomycosis outbreaks
Collaborations - Agreement reached for services for non-allergic asthma treatment
Collaborations - Alliance with U.S. NINDS to target neuromuscular disorders
Collaborations - Biotech company signs deal to profile selected compounds
Collaborations - Biotechnology companies sign research and development collaboration agreement
Collaborations - Companies collaborate on antidiarrheal compound crofelemer
Collaborations - Deal signed to identify natural compounds for Johnson & Johnson
Collaborations - Genotyping license agreement signed with DxS and BTG
Collaborations - License agreement entered related to gene targeted mice
Collaborations - Milestone achieved in collaboration with Biovitrum
Collaborations - Partnership focuses on cancer research support
Collaborations - Pharma company announces research collaboration with NovaThera
Collaborations - Pharmaceutical company signs biomarker research alliance
Collaborations - Profiling agreement signed with Neurocrine Biosciences, Inc.
Collaborations - Proteomics company and Biosite Incorporated announce collaboration
Colon Cancer - 5-Fluorouracil drugs affected hepatic fat content in patients with colon cancer
Complementary & Alternative Medicine - Herbal combination effective for prostate, urinary problems, trial results show
Complementary & Alternative Medicine - Microalgal technology company taps Russell Communications for IR and marketing
Complementary & Alternative Medicine - Myth of shark cartilage's curative benefits busted
Complementary & Alternative Medicine - Not enough evidence found to warrant use of herbal medicines for AIDS
Complementary & Alternative Medicine - The garlic component allicin prevents immune-mediated liver injury in mice
Computed Tomography - Multi-slice CT image quality allows visualization of the entire coronary tree
Congenital Disease - Developmental disorder in Roberts syndrome maps to chromosome 8p21
Coronary Artery Disease - Sildenafil induced smaller changes in hemodynamic pressures compared with ISMN
Cowden Disease - Use of rapamycin questioned
Cyclophosphamide - Dermal exposure to cyclophosphamide in hospitals discussed
Cystic Fibrosis - Research identifies specific pathway that causes inflammation in lung tissue
DNA Research - Alternating rise, fall of SCF-NIPA levels act as switch regulating cell division
Dementia - Evidence and acceptance grows for taking statin drugs to treat dementia
Dendritic Cell Vaccine - Activated antigen-presenting cells present chemically modified peptides
Dengue Fever - Cemetery is source of dengue vector
Depression - Are antidepressant drugs overprescribed in primary care?
Depression - OT, VP studied as novel psychiatric drug sources
Depression Treatments - Effects of SSRI treatment on corticolimbic connectivity characterized
Dermal Infection - Ethosomal erythromycin effective against murine deep skin infections
Dermatology - PAX3 antisense oligonucleotides complement cisplatin cytotoxicity in melanoma
Diabetes Research - GlucaGen HypoKit now available for severe hypoglycemic reactions
Diabetes Risk Factors - Anesthesia-induced hyperglycemia does not increase diabetes risk
Diabetes Therapy - Clinical trials resumed for type 2 diabetes drug CS-917
Diabetes Therapy - Metformin versus conventional approach for type 2 diabetes compared
Diabetes Therapy - Metformin works well in type 2 diabetes, especially for obese patients
Diabetes Therapy - Metoclopramide unnecessary in fasted diabetic patients before surgery
Diabetes Therapy - Mouse model suggest diabetics could provide their own insulin-producing tissue
Diabetes Therapy - Study identifies fat-secreted protein linked to insulin resistance
Diabetes Treatment - Study evaluates anomaly rates of insulin treatments
Diagnostics - Collagen type VI gene mutants screen patients with Bethlem myopathy
Diagnostics - Dynamic susceptibility-weighted perfusion images define glioma angiogenesis
Diagnostics - In situ hybridization can't detect hepatitis C RNA in all liver tissue samples
Diagnostics - License signed for novel renal injury marker
Diagnostics - Rising plasma angiogenin levels predict bladder cancer growth and recurrence
Diagnostics - Two-step gene profiling delineates colorectal cancer microsatellite status
Diet & Nutrition - Review examines mechanisms of altered fetal growth and coronary heart disease
Diet and Nutrition - Peripheral blood antioxidants change as chronic hepatitis C activity increases
Diet and Nutrition - Reformulated NUTRILITE DOUBLE X Multivitamin delivers more phytonutrients
Diet and Nutrition - Study shows kids have great leeway in deciding what they eat
Disease Associations - Chronic rhinosinusitis examined, nasal polyposis role in physiology established
Dolastatin - Dolastatin 11 conformations, analogues and pharmacophore discussed
Drug Abuse - Drugstore chain sets registers to prohibit sales of dextromethorphan to minors
Drug Abuse - Partnership for a Drug Free America selects communication firm
Drug Delivery - Aging and microwave effects characterized in alginate/chitosan matrices
Drug Delivery - Aloe Vesta Protective Barrier Spray launched
Drug Delivery - High duty cycles slow pore membrane recovery following sonoporation
Drug Delivery - Novel capsules show promise for delivery of poorly water-soluble drugs
Drug Delivery - Polyelectrolyte complex fibers show promise for controlled release
Drug Delivery - Surface modification of biodegradable polyesters improves drug targeting
Drug Development - Agreement reached with U.S. FDA for renzapride phase III trial
Drug Development - Approval granted to begin phase II trial for Indaflex
Drug Development - Cellular Genomics selects angiogenesis candidate, changes name
Drug Development - Clinical program initiated for potential novel treatment of asthma
Drug Development - Drug companies look beyond blockbusters for growth
Drug Development - Enrollment complete in phase III DIRECT trial evaluating Infergen plus ribavirin
Drug Development - Enrollment initiated in trial of M-Vax for patients with melanoma
Drug Development - IGIV selected by company as first therapeutic protein product for development
Drug Development - Inducible suicide gene therapy harnesses the power of caspase 8
Drug Development - Marketing program stepped up for new oral psoriasis product
Drug Development - Orally active pyrrolotriazines staunch tumor angiogenesis in mice
Drug Development - Patient screening in phase III ARISE trial concluded
Drug Development - Phase I trial initiated for HDAC inhibitor in patients with cancer
Drug Development - Phase I/II clinical studies initiated for the treatment of obesity
Drug Development - Phase II trial of Hematide for anemia begins
Drug Development - Phase IIb trial of BXL628 in benign prostatic hyperplasia initiated
Drug Development - Positive opinion granted for Humira in Europe for rheumatoid arthritis
Drug Development - Proanthocyanidins from sangue-de-adave bark have antinociceptive effects
Drug Development - Rapamycin exhibits dramatic antitumor activity in breast cancer models
Drug Development - Schering-Plough signs agreement for support in new HIV drug development efforts
Drug Development - Sotradecol injection for varicose veins launched in U.S. market
Drug Development - U.S. FDA grants approval for Allegra capsules
Drug Development - U.S. FDA grants approval for glyburide/metformin HCL tablets
Drug Discovery - Researchers to patent scientific technique
Drug Importation - Professional society warns against discount injectables bought offshore
Drug Resistance - Hepatocytes analyzed, significance of membrane microdomains indicated
Drug Resistance - RNA interference reverses multidrug resistance in animal studies
Drug Resistance - Recent use of antibiotics doubles your chances of being resistant
Drug Resistance - Short hairpin RNA re-sensitizes cancer cells to conventional chemotherapy
Eczema - Enrollment begins in additional phase I/II trial of drug candidate for eczema
Embryonic Stem Cell Research - Hematopoietic repopulating cells generated from ESC independent of ectopic HOXB4
Embryonic Stem Cell Research - TGF-beta signaling potentiates ESC differentiation to Pdx-1 expressing cells
Embryonic Stem Cell Research - p53 plays maintains ESC genetic stability by eliminating DNA-damaged ESCs
Endocarditis - AHA publishes statement on infective endocarditis
Endocrinology - Adiponectin functions as an autocrine factor in fat tissues
Endocrinology - Combined gene therapies control goiter mass in murine models
Endocrinology - Insulin resistance triggers hepatitis C-related liver steatosis and fibrosis
Endocrinology - Mammographic density may be associated with hormone use in postmenopausal women
Endocrinology - Thyroid hormone and alpha(V)beta(3) receptor interactions trigger angiogenesis
Endocrinology - VEGF protein is essential for pituitary gland neovascularization
Endometriosis - Conservative surgery for bladder endometriosis can ensure long-term relief
Endometriosis - Midkine may play role in development of endometriosis
Endometriosis - Treatment of endometriosis compares excision & ablative treatment modalities
Environmental Health - Recombinant activated factor VII reverses superwarfarin toxicity
Enzymology - Enzyme inhibitors have unintended effects on colon cancer metastasis
Enzymology - EphB4 is a potential therapeutic target in patients with mesothelioma
Enzymology - Major cyclooxygenases facilitate esophageal adenocarcinoma pathogenesis
Epidemic Surveillance - Method rapidly identifies/types respiratory pathogens for epidemic surveillance
Epidemiology - Abortions/neonatal mortality associated with T. evansi infection in camels
Epidemiology - In utero factors may affect cancer risk differently among ethnic groups
Epilepsy - Seizure-focused foundation lauds U.S. FDA approval of monotherapy for epilepsy
Epilepsy Therapy - Delta sleep-inducing peptide analogue highly effective in rats
Epilepsy Treatments - Valproate is implicated in congenital malformations children of epileptic women
Epstein-Barr Virus - EBV infection induces expression of the ATF-2/c-Jun in B but not B-CLL cells
Esophageal Cancer - Capecitabine and docetaxel used in first- and second-line therapy
Ethics - Are some medicines so good they should be free?
Fatty Liver Disease - Palmitic acid makes rodent liver cells self-destruct
Fibrinolysis - In vitro methods aim to improve understanding of plasminogen activation
Finance - Active Biotech's new share issue oversubscribed
Finance - Biopharmaceutical company announces proposed public offering of common stock
Finance - Biopharmaceutical firm commences exchange offer
Finance - Biotech company completes $3,557,892 private placement
Finance - Biotech company reports Q2 GAAP EPS of $0.46, non-GAAP EPS of $0.57
Finance - Biotech company to obtain up to $15,000,000 in equity financing
Finance - Biotech firm's stock approved for listing on American Stock Exchange
Finance - Company announces intention to offer up to $2 billion in senior notes
Finance - France-based biopharmaceutical company raises $42.16 million
Finance - Genomics company changes ticker symbol to DNAG
Finance - Oncology company reports 65% increase in revenues
Finance - Pharma company's registration statement becomes effective
Finance - Pharma firm raises $11.3M to commence two clinical trials
Finance - Pharmaceutical company added to 2005 Russell Indices
Finance - Pharmaceutical company raises $7 million in series C round of financing
Finance - Pharmaceutical company receives financing through technology funds
Finance - Pharmaceutical firm adopts rights agreement
Finance - Pharmaceutical firm files shelf registration statement with SEC
Finance - Pharmaceutical firm records profit of INR 351M
Finance - Pharmaceutical firm reports a 32% sales increase
Finance - Pharmaceutical firm's offers 8,500,000 shares of common stock
Finance - Therapeutic vaccines development company secures first financing round
Finance - U.S.$10M debt financing provided to Labopharm subsidiary
Financing - Stabilized rice bran company receives 1-year extension on loan
Gastroenterology - COX-2 antisense transfectants halt gastric cancer angiogenesis
Gastroenterology - Gene polymorphisms may predict a positive response to Crohn disease therapy
Gastroenterology - Immunosuppressive drugs in inflammatory bowel diseases assessed
Gastroenterology - Orocecal transit time is longer in non-alcoholic fatty liver disease patients
Gastrointestinal Tuberculosis - Gastrointestinal TB not an uncommon diagnosis in northeastern Parisian area
Gene Delivery - Degradation-resistant p53 gene transfer kills cancer cells
Gene Research - Altered nef/long terminal repeat sequences slow HIV-1 disease progression
Gene Research - NET-6 may suppress the growth and invasion of breast cancer
Gene Research - Select genes buoy Kaposi sarcoma-associated herpesvirus-related oncogenesis
Gene Transfer - Gene therapy expands the potential of interleukin-13 cytotoxin
Generic Drugs - Company extends line with Clotrimazole & Betamethasone Dipropionate Lotion
Generic Drugs - Expiring patent drugs may lose 80% share when generics hit market, study shows
Generic Drugs - Pharma company gains approval to market Metformin XL Tablets
Generic Drugs - Pharma company receives tentative approval for Zidovudine Tablets
Genetics & Genomics - Genomics company acquires 18% stake in German company
Genetics & Genomics - Research study examines gene therapy markets
Germinoma - Clinical characteristics and treatment outcome of CNS germinoma summarized
Glioma Tumors - Scorpion venom induces glioma cell apoptosis and inhibits glioma tumor growth
Grants - Michigan U health system receives $10 million NIA grant for Alzheimer research
Gynecology - Cyclooxygenase-2 and thymidine phosphorylase profile cervical cancer patients
Gynecology - FDG-PET employed in evaluation of vaginal carcinoma
Gynecology - Microsatellite profiles categorize endometrial cancers
HIV/AIDS & Dengue Fever - Dendritic cell precursors are permissive to dengue virus and HIV infection
HIV/AIDS Antiretroviral Therapy - Heparan sulfate targets HIV-1 gp120 coreceptor binding site
HIV/AIDS Drug Adherence - Couple-focused support improves HIV medication adherence
HIV/AIDS Drug Development - Artificial zinc finger fusions repress HIV-1 transcription and replication
HIV/AIDS Drug Dosing - Dose interval decrease more effectively controls viral load than increasing dose
HIV/AIDS Drug Resistance - Selective real-time PCR discriminates lamivudine resistant minor HIV-1 variants
HIV/AIDS Epidemiology - Decrease in drug resistance levels of HIV epidemic can be bad news
HIV/AIDS HAART - IRD associated with mycobacterial infections in HIV patients on HAART
HIV/AIDS HAART - Mitochondria are sensors for HIV drugs
HIV/AIDS HAART - Risk of triple-class antiretroviral drug failure declining in Denmark
HIV/AIDS Neurology - Morphine modulates chemokine gene regulation in normal astrocytes
HIV/AIDS Pathogenesis - HIV-1 zinc finger mutants with altered RNA binding specificities detected
HIV/AIDS Pathogenesis - Resting naive CD4+ cells massively infected/eliminated by X4-tropic SHIV
HIV/AIDS Prevention - Researchers offer new approach for testing potential HIV vaccines
HIV/AIDS Prevention - Why were the HIV prevention trials in commercial sex workers abandoned?
HIV/AIDS Risk Factors - Adolescent groups identified as at most risk for acquiring HIV infection
HIV/AIDS Risk Perception - Prevention strategies should address risk perception associated with HAART
HIV/AIDS Stigma - Nine-item scale measures AIDS-related stigma in South Africa
HIV/AIDS Therapy - IL-2 plus antiretroviral therapy increases CD4 counts but has no effect on atopy
HIV/AIDS Treatment - High degree on agreement of HIV treatment recommendations derived from genotypes
HIV/AIDS-Associated Infection - Some HIV protease inhibitors can inhibit Encephalitozoon intestinalis growth
HIV/AIDS-Related Dementia - HIV-1 gp120 and Tat induce oxidative stress in brain endothelial cells
HIV/AIDS-Related Kaposi Sarcoma - c-kit expression in KS lesions can be detected by immunohistochemistry
HIV/AIDS-Tuberculosis Coinfection - TB incidence remains high despite isoniazid prophylaxis in HIV-infected persons
Head and Neck Cancer - Compound from Chinese medicine shows promise in head and neck cancer
Head and Neck Cancer - ERCC4 variants improve recovery after radiotherapy for oropharyngeal cancer
Headache and Migraine - Group sequential, adaptive design effective for migraine trial
Headache and Migraine - Medical technology company completes enrollment in migraine study
Healthcare Access - Indiana residents making use of prescription assistance clearinghouse
Healthcare Coverage - Economists demand free HIV medications for all
Healthcare Coverage - Prescription drug assistance program opens Iowa chapter
Heart Failure - Use of multidisciplinary unit reduces number of HF hospital admissions
Heart Surgery - Renal dose dopamine heightens risk of postoperative atrial fibrillation
Hematology - Cell types dictate the interaction of von Willebrand factor and factor VIII
Hematology - RPS 19 depletion blunts erythropoiesis in Diamond-Blackfan anemia models
Hematology - Suppressed hematopoiesis is persistent in chronic hepatitis C patients
Hematology - TNF-alpha matures leukemia cells into antigen-presenting cells
Hematopoiesis - Hematopoietic cells maintain hematopoietic fates upon entering the brain
Hemophilia - Redesigned protein accelerates blood clotting
Hepatic Veno-Occlusive Disease - Company gets go-ahead for phase III clinical trials with Defibrotide
Hepatitis B Prevention - Hepatitis B vaccine doses protect patients regardless of dialysis type
Hepatitis B Virus - Fulminant hepatitis strikes hepatitis B carriers with acute liver disease
Hepatitis B Virus - Occult hepatitis B may hamper interferon in hepatitis C coinfected patients
Hepatitis B Virus - Patients with chronic hepatitis B produce high levels of T cell activator
Hepatitis B Virus - Pro-inflammatory cytokine sustains liver injury in chronic hepatitis B
Hepatitis B Virus - Viremia fluctuates in chronic hepatitis B carriers
Hepatitis C - Pharma company provides update on hepatitis C virus R&D pipeline
Hepatitis C Therapy - Short courses of peginterferon clear hepatitis C genotypes 2 or 3
Hepatitis C Virus - Agreement signed for celgosivir hepatitis C drug in phase 2 clinical development
Hepatitis C Virus - Interferons use IRES-dependent mechanisms to block hepatitis C replication
Hepatitis E Epidemiology - Hepatitis E infection produces unexplained acute hepatitis cases
Hodgkin Lymphoma - Hodgkin disease reclassified as Hodgkin lymphoma
Hodgkin Lymphoma - bcl-2 expression independent predictor of poor outcome in Hodgkin lymphoma
Hormone-Replacement Therapy - Effects of hormone-replacement therapy on brain tissue are investigated
Hormones - Parathyroid hormone examined, kidney cell sensitivity and responses defined
Hormones - Prolactin release studied, role of prolactin-releasing peptide clarified
Hypertension - ATP III approach improves detection of CHD burden due to elevated cholesterol
Hypertension - AT1 -receptor antagonism reverses blood pressure elevation
Hypertension - Diuretics unsurpassed in preventing hypertension complications in black patients
Hypertension - Drug could be future treatment for hypertensive African Americans
Hypertension - L-NAME-induced hypertension is associated with upregulating antioxidant enzymes
Hypertension - Review discusses in vivo hypotensive, cardiodepressant effects of cannabinoids
Hypertension Therapy - C-reactive protein levels predict perindopril-indapamide efficacy
Hypopharyngeal Cancer - Chemoradiation therapy with or without salvage surgery compared
Infection - Candida blood isolates examined, role of slime and proteinase clarified
Infectious Diseases - Anti-infectives-focused company provides corporate update
Influenza - Mouse studies of oseltamivir show promise against H5N1 influenza virus
Influenza Vaccine - Flu vaccine granted fast track status by U.S. FDA
Information Technology - CR Toolkit now available under SAS Version 9.1.3
Information Technology - LabSmart software audit package launched
Information Technology - New oral cancer risk assessment tool added to information suite
Information Technology - Pharma company selects regulatory compliance software
Inovirus - Chemoattractant protein production examined, viral induction shown
Insomnia Therapy - Eszopiclone safe and effective in elderly patients
Intracranial Germinoma - Benefit of spinal irradiation in treating intracranial germinoma found lacking
Ischemia - Review focuses on statin-mediated protection against I/R injury and infarction
Juvenile Idiopathic Arthritis - Immune responses to hsp60 epitopes in juvenile idiopathic arthritis published
Kaposi Sarcoma-Associated Herpesvirus - Exonuclease and host shutoff functions of KSHV SOX are genetically separable
Kaposi Sarcoma-Associated Herpesvirus - Lytic transactivator RTA induces KSHV latency-associated nuclear antigen
Kidney Stone Therapy - Caffeic acid phenethyl ester prevents ESWL-induced oxidative damage
Kidney Transplantation - Early post-transplant blood cyclosporine level predicts rejection
Kyphoplasty - Vertebroplasty and kyphoplasty study update presented at conference
Lead Exposure - Moderate lead exposure elicits neurotrophic effects in cerebral cortical NSCs
Leishmaniasis - Leishmania donovani trypanothione reductase characterized
Leptin Studies - Weight loss increases leptin receptor and ghrelin receptor expression
Leptospirosis & Dengue Outbreak - Concurrent outbreak of leptospirosis and dengue occurred in Mumbai city slums
Leucovorin - Decrease of tumor volume correlated with stage change after chemoradiotherapy
Leukemia - Termination of pregnancy may not be necessary when treating leukemia
Liver Disease - Hy's Rule validated for drug-induced liver damage
Liver Failure - Type and extent of hepatectomy drives post-surgical complications
Local Anesthetics - Bupivacaine and Levobupivacaine depress cardiac sympathetic neurotransmission
Lung Cancer - New data show treating lung cancer patients preoperatively may improve outcomes
Lung Cancer - Patient treated with platinum therapy in small cell lung cancer clinical trial
Lung Cancer - Positive clinical data from combination regimens in lung cancer therapy reported
Lung Cancer - Researchers find potential Celebrex target in lung cancer
Lung Cancer - Results of preclinical lung cancer study in mice reported
Malaria - P. falciparum ATPase studied, structure and function clarified
Malaria - Deltamethrin exposure affects host resistance to Plasmodium infection
Malaria - Fetuses acquire Plasmodium falciparum inhibitory antibodies transplacentally
Market Analysis - Authorized generics pave the way for lifecycle management
Market Analysis - Novartis retains number one rank with managed care executives
Marketing - North Carolina-based pharma further expands nationwide sales force
Marketing - Report: Competitive positioning critical factor in oncology resource allocation
Medical Devices - Drug-eluting stents tested in two patients with peripheral arterial disease
Medical Devices - Medical device company launches endovascular technology in China
Medicare - Medicare partnership to launch grassroots education campaign
Membrane Structure - Lung caveolae examined, water and solute permeability revealed
Men's Health - Growth factor therapy may help men with age-related erectile dysfunction
Meningioma - Hyperosmolar mannitol evaluated as a liquid tumor embolization agent
Menopause - Estrogen is linked to misoprostol activity
Menopause - Gel reduces hot flashes in menopausal women
Mental Health - Grant to increase capacity of Vermont mental health treatment services
Mental Health - Serotonin gene polymorphisms do not interact in schizophrenia
Mental Health - Study examines need for funding social services for women
Mental Health Therapy - Testosterone propionate has anxiolytic activity in rats
Mergers & Acquisitions - Acquisition of Salmedix completed
Mergers & Acquisitions - Antibody maker acquires Stressgen Bioreagents
Mergers & Acquisitions - Biotechnology device company announces intention to acquire Surgica Corporation
Mergers & Acquisitions - Company announces stockholder approval of merger with GlaxoSmithKline
Mergers & Acquisitions - Dialysis services company acquires apheresis program
Mergers & Acquisitions - Distributor to be acquired by McKesson
Mergers & Acquisitions - Final purchase agreement to buy Fournier Pharma finalized for 100% of company
Mergers & Acquisitions - Healthcare services company to acquire pharmaceutical distributor
Mergers & Acquisitions - Maternal and neonatal health company expands services in Florida
Mergers & Acquisitions - Pharma company signs purchase agreement with Guangdong Medicine Group
Mergers & Acquisitions - Pharma firm signs deal for sale of U.S., Canadian consumer medicines business
Mergers & Acquisitions - Pharmaceutical company caring for the elderly to acquire excelleRx
Mergers & Acquisitions - Privately held U.K. biotechnology company Ionix Pharmaceuticals acquired
Mergers & Acquisitions - Registration statement for acquisition of Accredo Health declared effective
Mergers & Acquisitions - Report: Healthcare M&A market heats up and VC funding keeps flowing
Mergers & Acquisitions - Scientific and technical electronics company to acquire NovAseptic AB
Metabolic Syndrome - Study explores links between metabolic syndrome and altered CoQ10 metabolism
Microbicidal Contraceptives - Antimicrobial peptides have potential as microbicidal contraceptives
Multiple Sclerosis - ASCT: A potential rescue therapy for unresponsive malignant MS
Multiple Sclerosis - Phase II clinical trial initiated in patients with multiple sclerosis
Mycobacteria Exposure - Workplace exposure to mycobacteria cause of hypersensitivity pneumonitis
Mycobacterium Tuberculosis - Fluoroquinolone resistance protein from M. tuberculosis mimics DNA
Mycobacterium Tuberculosis - GM-CSF production disruption in lungs affects ability to control MTB infection
Mycobacterium Tuberculosis - Laboratory cross-contamination with MTB identified using NVTR typing
Mycobacterium Tuberculosis - Nitroimidazopyran PA-824 active against multidrug-resistant MTB
Mycobacterium Tuberculosis - Nitroimidazopyran PA-824 bactericidal against Mycobacterium Tuberculosis
Mycoplasma Pneumoniae - M. pneumoniae infection studied, role in airway collagen deposition shown
Myocardial Infarction - Enough concerns may exist to warrant reconsideration of CV safety of all NSAIDs
Myocardial Infarction - Intramyocardial microdepot injection enhances cell transplantation
Myocardial Infarction - Study to determine best reperfusion strategy in elderly AMI patients is feasible
Myometrium - Maxi-K channel localization to caveolae revealed in myometrium study
Natural Products - Hemorrhagic septicemia rhabdovirus examined, antiviral activity revealed
Neisseria Gonorrhoeae - Curcumin inhibits Neisseria Gonorrhoeae-induced NF-kappa B signaling
Neisseria Meningitides - NO detox enhances N. meningitides survival in macrophages/nasopharynx
Neisseria Meningitides - Outer membrane vesicle vaccine against serogroup A N. meningitides developed
Neural Development - Wnt signaling has multiple functions in neural development
Neural Stem Cell Research - 3D culture predicts response of neural stem cells to cytokines
Neural Stem Cell Research - Cyclin E acts under hox-gene control as cell fate determinant in developing CNS
Neural Stem Cell Research - NSSRs/TASRs/SRp38s function as splicing modulators via binding to pre-mRNAs
Neural Stem Cell Research - Nestin-expressing neural SCs identified in scar following myocardial infarction
Neuroblastoma - Disruption of cooperation between Ras and MycN promoted growth arrest
Neuropathy - Old drug may find new use against side effect of cancer treatment
Neuroscience - GABA(B1) signal analyzed, requirement for membrane spacing shown
Neuroscience - MRI perfusion studies track the vascular dynamics of brain tumors
Nitric Oxide - eNOS may limit LV remodeling and dysfunction under chronic pressure overload
Non-Small Cell Lung Cancer - Canada approves Tarceva as treatment for metastatic non-small cell lung cancer
Non-Small Cell Lung Cancer - Journal publishes report on Tarceva trial
Non-Small Cell Lung Cancer - Pivotal phase III Tarceva study published in journal
Nosocomial Infections - Staph compound immunogenicity study in cardiac patients meets primary endpoints
Nutrition - Intestinal niacin uptake examined, mechanism and regulation defined
Obesity Education - FPA comments on call for obesity warning labels, soft-drink targeted messages
Obesity Risk Factors - Fatty acid amide hydrolase polymorphism is linked to being overweight
Obesity Surgery - Benefits of minimally invasive bariatric surgeries for obesity weighed
Obesity Therapy - Melanin-concentrating hormone 1 receptor antagonist fights obesity
Obesity and Diabetes - Fenofibrate prevents rosiglitazone-induced body weight gain
Obstetrics - Maternal obesity, not thinness, is linked to offspring blood pressure
Obstetrics - Multiple abortions may be predictive of vaginal bleeding during pregnancy
Obstructive Sleep Apnea - CPAP therapy protects against CV death in patients with sleep apnea syndrome
Oncogene - microRNA polycistron is potential oncogene
Oncology - ATM protein blockade makes prostate cancer cells more sensitive to radiation
Oncology - Assessment is critical when treating older women with breast cancer
Oncology - Complementary therapies bolster TRAIL-mediated death in breast cancer cells
Oncology - Gene ratios forecast clinical outcomes in patients with mesothelioma
Oncology - Hypoxia-driven angiogenesis prompts pancreatic cancer progression
Oncology - Platinum-based chemotherapy for metastatic breast cancer is safe and effective
Oral Health - Novel liquid dentifrice formulation controls odorigenic bacteria
Oral Health - Transcript profiles find genetic markers in premalignant oral epithelia
Osteogenic Sarcoma - Cancer drug granted orphan-drug designation for osteogenic sarcoma treatment
Osteopenia - Clinical trial shows promise with nitric oxide-donating compound in bone disease
Osteoporosis - Attention focused on emerging oral complication from supportive cancer therapy
Osteoporosis - PREOS new drug application accepted for review by U.S. FDA
Overactive Bladder - Company acquires U.S. rights to SANCTURA
Pain Management - Acute i.v. morphine disrupts sleep in pain-free young adults
Pain Management - Dosing begins in cohort 3 of phase II study of SABER-Bupivacaine
Pain Management - Licensing agreement made to investigate opioid analgesics in pain treatment
Pain Management - Novel vanilloid receptor antagonist has antinociceptive effects
Pain Management - Study evaluates combined systemic opioids for pain relief during labor
Pain Medicine - European phase II/III study of Dyloject meets primary endpoint
Pancreas Cancer - All-trans retinoic acid inhibited cell proliferation but enhanced cell invasion
Patents - ACE System developer strengthens IP estate with four new patents
Patents - Biotech company strengthens patent portfolio on neuregulins products
Patents - Blood volume expander developer announces new patent in China
Patents - Medical device company receives patent for hemodiafiltration delivery module
Patents - Pharmaceutical company issued U.S. drug delivery system patent
Patents - Two patent applications filed on stem cell devices
Patents - U.K. patents granted covering siRNAs targeting VEGF and HCV
Patents - U.S. Patent issued for ultrasonics-assisted transdermal drug delivery technology
Patents - U.S. patent granted for interferons for treating hepatitis C, viral diseases
Pediatric Anesthesia - Novel method identifies latent errors in procedural sedation
Peptide Research - Peptide mimetic synthesized, high Grb2 SH2 domain-binding affinity revealed
Peripheral Arterial Disease - Brazil patients receive paclitaxel-coated stent for peripheral arterial disease
Personnel - Biopharma firm names Steve Thornton to board of directors
Personnel - Biotech company announces addition of chief financial officer
Personnel - Biotech company appoints Simcha Edell as chief financial officer
Personnel - Biotech company names Stephen Grant chief medical officer
Personnel - Biotechnology company names members to board of directors
Personnel - Cardiovascular surgery device manufacturer establishes board of advisors
Personnel - Chemical company elects member to board of directors
Personnel - Chuck Chukwumerije, PhD, named VP, quality assurance, by pharmaceutical company
Personnel - Claire M. Fraser, PhD, named to National Science Advisory Board for Biosecurity
Personnel - Consulting company names healthcare sector lead
Personnel - Contract research organization appoints executive officer
Personnel - DNA-based diagnostics company names Trevor L. Hawkins to board of directors
Personnel - Dr. Cy Stein joins scientific advisory board
Personnel - Dr. Joseph Eiden named vice president, clinical research and medical affairs
Personnel - Dr. Shahzad Malik named to board of directors of immune-focused company
Personnel - Gene therapy company adds John Walker to board of directors
Personnel - Hospital transport provider appoints executive to board of directors
Personnel - Human Genome Sciences names Barry A. Labinger executive VP and CCO
Personnel - Hythiam appoints drug courts expert as VP of government programs
Personnel - Jane M. Nani, MD, joins endocrinologists at Illinois fertility centers
Personnel - Joanna Horobin appointed chief executive officer by oncology-focused company
Personnel - John J. Hamre, PhD, elected to research, engineering company board of directors
Personnel - John J. Reddington named COO of cardiovascular therapies-focused company
Personnel - Kenneth L. Rice Jr. named chief financial officer at biotech firm
Personnel - Mark A. Kahil named VP of investor relations by cell therapies-focused company
Personnel - Pharma company announces retirement of senior manager
Personnel - Pharma company appoints business development manager
Personnel - Pharma company appoints member to board of directors
Personnel - Pharma company appoints new board member
Personnel - Pharma company appoints senior director of clinical development
Personnel - Pharma marketing services provider names business development executives
Personnel - Pharmaceutical company announces resignation of president
Personnel - Pharmaceutical company makes board appointment
Personnel - Pharmaceutical company strengthens senior leadership team
Personnel - Pharmaceutical development company announces resignation of CEO
Personnel - Ramon W. Mohanlal named chief medical officer at Interleukin Genetics
Pest Resistance - Transgenics provide sustainable pest resistance in genetically enhanced crops
Pharmaceutical Research - 5-HT2 antagonists lower benzodiazepine withdrawal anxiety in rats
Pharmaceutical Research - Novel rat catalepsy test may help identify antiparkinsonian drugs
Pharmaceutical Research - Research shows pharma companies using clinical results to drive marketing
Pharmaceutical Research - Research study examines how to win investigators in a competitive market
Pharmaceutical Research - Study examines pharma resource allocation from preclinical to phase III
Philanthropy - Production company launches child survival impact campaign
Pneumocystis Carinii - Alveolar epithelial cells have a significant role in host responses during PCP
Pneumonia - Statins protect from death from pneumonia
Poxvirus Vaccine - Murine interferon lambdas exhibit antiviral activity against poxvirus
Premenstrual Syndrome - Calcium and vitamin D intake may lessen incidence of premenstrual syndrome
Product Licensing - Company inks licensing agreement for use of MediVas technology
Product Licensing - Company licenses CRx-026 territory rights to HenKan
Product Licensing - Flourocarbon-based oxygen delivery technology sublicensed to ImaRx Therapeutics
Product Licensing - StemCells, Inc., gains access to human stem cell immortalization technology
Product Licensing - Topical treatment for radiation dermatitis licensed in Portugal and Brazil
Prostate Cancer - Drug therapy for benign prostatic hyperplasia overviewed
Prostate Cancer - Effect of androgen suppression on hemoglobin in prostate cancer analyzed
Prostate Cancer - Enrollment complete in trial of therapy for androgen-independent prostate cancer
Prostate Cancer - Interference with HH-GLI signaling inhibits prostate cancer
Prostate Cancer - Membrane type I-matrix metalloproteinase is linked to prostate cancer invasion
Proteases - IgA cleavage analyzed, influences of hinge length and composition defined
Proteomics - GIRK5 surface expression analyzed, role of tyrosine phosphorylation clarified
Proteomics - Galectin-7 promotes malignant tumor formation
Proteomics - Gene 33 protein shuts down apoptosis to encourage breast cancer growth
Proteomics - Genomic maps confirm p53 management of host anti-tumor activities
Proteomics - The Bcl-2 protein emits proangiogenic signals
Proteomics - Transforming growth factor-beta proteins regulate new vessel formation
Pulmonary Arterial Hypertension - Bosentan in pulmonary arterial hypertension study useful for Eisenmenger
Pulmonary Arterial Hypertension - Company announces PDUFA date for Thelin NDA
Q-Fever - Seroprevalence rates of Q-fever are high in febrile individuals in Mali
RNA Interference - Thioribonucleoside modification enhances short interfering RNA efficacy
RNA Research - Hunt for human genes involved in cell division under way
RNA Research - Single screen, ready-to-transfect siRNA libraries launched
Rabies - Company announces human monoclonal antibody combination against rabies
Rabies - Fluorometric cell-ELISA quantifies rabies infection and heparin inhibition
Receptors - Glucocorticoid receptor inhibiton studied, structure-function analysis reported
Restenosis - Study did not find relationship between nickel allergy and in-stent restenosis
Retrovirus - HAART safe/effective in HIV-infected children with advanced disease
Rheumatology - Functional genomic screens reveal new osteoarthritis mediators
Rheumatology - Hepatitis C virus infection is not a cause of fibromyalgia
Rosacea - Company announces new product for the topical treatment of rosacea
SARS - Structure of SARS coronavirus frameshift signal elucidated
Salmonella - StrSPF/GF mice similar for Salmonella Enterica serovar Typhimurium colitis study
Sexual Health - Study focuses on assessing & managing women's sexual dysfunctions
Sexually Transmitted Disease - Asymptomatic rectal infections support routine STD screening
Skin Cancer - Researchers describe new approaches to medical treatment of basal cell carcinoma
Sleep Apnea - Researchers investigate pharma treatments for sleep apnea
Solid Organ Transplantation - Anti-CMV prophylaxis reduces morbidity and mortality
Spinal Cord Injury - Neural SCs delivered to injured cervical spinal cord by intrathecal injection
Spine Development - Intervertebral disc infection slows spine development
Staffing - Pharmaceutical companies better served by in-house staffing, not outsourcing
Statins - Even in high risk patients statin recommendations are not achieved
Statins - Factors influencing pravastatin treatment outcome identified
Status Epilepticus - Calcium-channel blocker verapamil may be useful in treatment
Stem Cell Research - Adventitial progenitor cells contribute to arteriosclerosis
Stem Cell Research - Committee approves stem cell policy enhancements
Stem Cell Research - Dr. Robert Lanza testifies before Senate subcommittee
Stem Cell Research - Exposure of aged satellite cells to serum from young mice rejuvenates the cells
Stem Cell Research - HSC mobilization accelerates renal recovery independent of SC contribution
Stem Cell Research - Mesenchymal stem cells may alleviate peripheral vascular disease
Stem Cell Research - Suspension bioreactors allow large-scale expansion of mammary SC aggregates
Stem Cell Transplantation - Autologous mesenchymal stem cell transplantation improves recovery after stroke
Stem Cell Transplantation - BM-derived mesenchymal stem cells treat neurodegenerative brain disorders
Stem Cell Transplantation - CD34+ cell dose plays role in preventing late infections in pediatric SCT
Stem Cell Transplantation - HSCT complications increase the likelihood of low lean body mass index
Stem Cell Transplantation - Reduced-intensity conditioning decreases B. obliterans incidence after AHSCT
Stem Cell Transplantation - Society unveils coloring book to help children receiving stem cell transplants
Stents - CP stent is suitable for treating vessel stenosis in CHD in children and adults
Stroke - Partnership to develop and market Desmoteplase
Surgical Technology - CE Mark approval granted for polymer-free drug-eluting stent for cardiology
Surgical Technology - Medical technology company commercially releases thoracic stent graft system
T-Cell Immunity - Decay-accelerating factor modulates induction of T cell immunity
Tamoxifen - Genetic variation in tamoxifen-metabolizing enzymes associated with survival
Thyroid Cancer - Differentially expressed genes mark thyroid papillary carcinomas
Tissue Engineering - Autologous epidermal cells induce wound closure of neurotrophic ulcerations
Tissue Engineering - Bone marrow cell growth varies between 2D and 3D alginate hydrogels
Tissue Engineering - Gamma-PGA/chitosan composite matrices promising for tissue engineering
Tissue Engineering - Hyalograft C safe and effective for treatment of articular cartilage lesions
Tissue Engineering - Macroporous bicontinuous materials developed as scaffolds for tissue engineering
Tissue Engineering - Osteoblast-like cells differentiate on hydroxyapatite ceramic bone substitute
Tissue Engineering - Porcine/human scaffold determines heart valve potential for monocyte attraction
Tissue Engineering - Synthetic nanofibrillar matrix promotes cell organization and morphogenesis
Tissue Engineering - Viable autologous semilunar heart valve can be created from stem cells
Tobacco Use - Researchers report discovery of molecular basis of nicotine dependence
Transplant Medicine - Combination therapy is problematic after hepatitis C-related liver transplants
Transplant Medicine - Low dose cyclosporine and interleukin 10 halt lung transplant acute rejection
Tuberculosis - Isolated positive sputum cultures appear infrequently during TB treatment
Tuberculosis - Tuberculosis should not be part of the clinical case definition of AIDS in India
Tuberculosis Vaccine - Carboxy end of M. tuberculosis deformylase required for enzyme activity
Tumorigenesis - CD95 has tumor promoting activities
Type 2 Diabetes - Takeda acquires rights to DPP4 inhibitors formerly granted to services provider
Tyrphostin Inhibitors - Tyrphostin inhibitors of cytokine signaling identified
Vaccine Development - Pharma company receives grant to develop thermostable vaccines
Vaccine Development - U of Saskatchewan offered $5.6 million for research into vaccines for newborns
Vector Development - Adenovirus CELO vector conveys suicide genes to cancer cells
Vector Development - Cytomegalovirus promoter expression enhanced by exposure to DNA damage agents
Vector Development - DNA shuttling between plasmid vectors resolves preservation concerns
Vector Development - PEGylated gelatin nanoparticles offer systemic delivery of therapeutic genes
Vector Development - RGD fiber-mutant vectors raise the safety profile of melanoma gene therapy
Veno-Occlusive Disease - C282Y allele is risk factor for hepatic veno-occlusive disease after HSCT
Venous Thromboembolic Events - EC okays new use of Arixtra for prevention of VTE in abdominal surgery
Virology - Adenoviral insulating sequences optimize radiation controlled gene expression
Virology - Genetic loci regulate antibody response to adeno-associated virus and factor IX
Virology - HIV values remain stable in hepatitis C coinfected patients on peginterferon
Virology - Hepatitis B virus genotype drives interferon efficacy
Virology - Measles virus vector bearing echistatin causes tumor regression
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