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Cancer Therapy

Artificial glioma tumor suitable for NMR spectroscopic study

Published in Drug Week, August 12th, 2005

An artificial tumor model enables nuclear magnetic resonance (NMR) spectroscopic analysis of chemotherapy-induced apoptosis.

In a recent study from the United States, an "artificial tumor method was developed to study cells inside the sensitive volume of an NMR spectrometer during growth and apoptosis."

In this system, the artificial tumor "was composed of a 50:50 mixture of tightly packed porous collagen and nonporous polystyrene microspheres," explained A. Mancuso and colleagues at the University of Pennsylvania. "The porous collagen served as a growth surface for the tumor cells, and the nonporous polystyrene served as a structural support to...

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