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Neural Stem Cell Research

3D culture predicts response of neural stem cells to cytokines

Published in Drug Week, August 12th, 2005

Three-dimensional culture predicts the response of neural stem cells to cytokines.

"The effect of growth factors on the 3-dimensional culture of neural stem cells has not been reported. We studied the effect of basic fibroblast growth factor (bFGF) on cultured rat neural stem cells in a 3-dimensional culture," scientists in Japan report.

"We cultured rat neural stem cells in collagen gel matrix for 3-dimensional culture and examined the effect of bFGF under such culture conditions. After 4 days culture," wrote T. Itoh and colleagues at Kinki University in Osaka, "the cell density in the bFGF treatment roup was 12 times that of the nontreatment group,...

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