Drug Week

Genomics - Biotech company's research on gene expression patterns in the brain complete

Geriatrics - The elderly require lower initiation and maintenance doses of warfarin

Glioma - Low-molecular weight caldesmon a potential serum marker for glioma

Gynecology - Company announces updated labeling for Mifeprex

HIV Therapy - Pharma company receives U.S. FDA approval for Zidovudine Tablets

HIV-1-Associated Dementia - HIV dementia related to changes in molecular factors involved in infection

HIV-1/Tuberculosis Coinfection - Serum neopterin highly elevated in HIV/TB coinfection + CD4 <200/mm³

HIV/AIDS Diagnostics - Evolving technologies for HIV diagnostics benefit resource-limited areas

HIV/AIDS Diagnostics - Low-cost assays available to monitor HAART in resource-poor settings

HIV/AIDS Diagnostics - Total lymphocyte count helps predict low CD4 count in low-resource setting

HIV/AIDS Drug Development - Antigene PNA targeted to proviral HIV-1 DNA inhibits viral replication

HIV/AIDS Drug Development - Fermented P. tinctorium Aiton extract suppresses acute HIV-1 infection

HIV/AIDS Drug Development - Measles virus inhibits HIV-1 replication in lymphoid tissues

HIV/AIDS Drug Development - New drug targets for HIV needed

HIV/AIDS Drug Development - Peptides derived from HIV-1 RT are inhibitors of the viral integrase

HIV/AIDS Drug Development - Peptides derived from HIV-1 reverse transcriptase inhibit viral integrase

HIV/AIDS Drug Development - Small molecule inhibitor of ATM kinase suppresses drug-resistant HIV-1 infection

HIV/AIDS Drug Development - Thymidine analogue derivatives suppress multidrug-resistant HIV-1 RT

HIV/AIDS Drug Development - Tn5 transposase target screen identifies HIV-1 inhibitors

HIV/AIDS Education - Individuals in Iran have fairly good AIDS-related knowledge

HIV/AIDS Epidemic - HIV-1B and C subtypes have different epidemic potentials

HIV/AIDS Epidemiology - HIV-1 subtype C/HIV-2 subtype A are major subtypes circulating in south India

HIV/AIDS GBV-C Coinfection - Prevalence of Gb virus C in perinatally HIV-infected children is small

HIV/AIDS HAART - Changing treatment indications contributed to improved survival in HIV/AIDS

HIV/AIDS HAART - Continuous saquinavir treatment progressively suppresses HIV-1 expression

HIV/AIDS HAART - GIQ predicts virologic response among patients with at least 3 PI mutations

HIV/AIDS Immunology - Orchestrated action of different immune mechanisms decide HIV infection outcome

HIV/AIDS Mathematical Model - B-spline model studies multiple longitudinal biomarkers/survival in HIV/AIDS

HIV/AIDS Pathogenesis - HIV-1 Vpr plays active role in viral offensive strategies

HIV/AIDS Pathogenesis - HIV-1 uncoating requires cellular activation

HIV/AIDS Pathogenesis - Innate-immunity effector cells marker of CD4+ cell loss in pediatric HIV/AIDS

HIV/AIDS Pathogenesis - SEN virus seroprevalence in HIV+ patients linked to HIV-replication

HIV/AIDS Pediatrics - HIV-infected children have poorer qualitative antibody response to PnCV

HIV/AIDS Pediatrics - Population-specific infant mortality rates guide HIV and infant feeding policy

HIV/AIDS Prevention - U.S. Senate increases microbicide funding for a total of $42 million

HIV/AIDS Research - HAART suppresses viral load in macaques infected with RT-SHIV

HIV/AIDS Therapy - FDA grants fast track status for investigational HIV protease inhibitor

HIV/AIDS Therapy - Plasma leptin increases early during HAART independent of body weight

HIV/AIDS Therapy - Uganda first lady, foundation president dedicate AIDS clinic in Kampala market

HIV/AIDS Treatment - Intracellular cytokines may model immunoregulation of abacavir hypersensitivity

HIV/AIDS Treatment - Phase 2b dosing begun in monotherapy trial for 'oral entry inhibitor' HIV drug

HIV/AIDS Tuberculosis Coinfection - HAART plus TB DOT strategy improves outcome of HIV/TB coinfected patients

HIV/AIDS Vaccine - BCG is a potential vehicle for use in HIV vaccine development

HIV/AIDS Vaccine - Discovery and development services company awarded NIH contract

HIV/AIDS Vaccine - Single round PCR and cloning method used to develop HIV vaccine

HIV/Hepatitis C Coinfection - Pegylated interferon alpha-2a effective/well-tolerated in HIV/HCV coinfection

HIV/Tuberculosis Coinfection - Risk of resistance in HIV/TB coinfection depends on rifampin dosing schedule

HLA-A Typing - Sequencing strategy reliable and efficient for high-resolution HLA-A typing

Head & Neck Cancer - Transfected p16 rebuffs salivary cancer cell proliferation

Head Lice - PerFoam demonstrates safety and 96% efficacy in phase II/III study

Healthcare Access - Survey on emergency care results reported

Healthcare Coverage - Pharmacy benefit management group reports 7.2% drug trend in 2004 report

Heart Disease - ADH1C genotype modifies relationship between alcohol consumption and CHD risk

Heart Disease Risk Factors - Cardiovascular risk in Southeastern United States examined

Heart Failure - Alpha₁ -adrenoceptor block may contribute to effects of carvedilol

Helicobacter Pylori - DNA MMR deficiency in H. pylori infection increase mutated risk in GI mucosa

Hematology - Hepatitis C is a cofactor for vascular access thrombosis in dialysis patients

Hematology - Lamivudine prophylaxis fights hepatitis B reactivation in cancer patients

Hemophilus Influenzae Outbreaks - Invasive Hemophilus influenzae serotype outbreak has occurred in infants

Heparin - Registry will provide insights on heparin-induced thrombocytopenia

Hepatitis B - Identification of a protein important for hepatitis B replication

Hepatitis B Therapy - Differentially expressed genes are targets for hepatitis B containment

Hepatitis B Therapy - Lentiviral vectors containing hammerhead ribozymes end hepatitis B activity

Hepatitis B Therapy - Pediatric chronic hepatitis B patients respond to lamivudine therapy

Hepatitis B Virus - AST surpasses ALT for screening liver injury in hepatitis B carriers

Hepatitis B Virus - Agreement signed to recover genetic information from clinical serum samples

Hepatitis B Virus - Biopharmaceutical company comments on data from hepatitis B treatment study

Hepatitis B Virus - Lamivudine helps patients overcome HBV-related decompensated liver cirrhosis

Hepatitis B Virus - Phase III clinical evaluation of tenofovir disoproxil fumarate begins

Hepatitis C Virus - Liver transplant recipients with hepatitis C require lower doses of tacrolimus

Hepatitis C Virus - Transgenic mice model extrahepatic manifestations of chronic hepatitis C

Hepatocellular Cancer - SEN virus infection not major cause of hepatocellular carcinoma

Hepatology - Combined models assess hepatitis C-related liver fibrosis

Herpes Labialis - Phase 2 study of herpes labialis treatment successfully completed

Herpes Simplex Virus - Universal screening for herpes infection could reduce perinatal infection

Hormone Receptors - Phenobarbital response unit studied, binding sites elucidated

Human Herpesvirus Type 8 - Salivary lactoferrin recognized by human herpesvirus-8

Hypertension - Amlodipine can improve LV functions in patients with arterial hypertension

Hypertension - Enrollment completed in trial of pulmonary arterial hypertension treatment

Hypertension - National Heart, Lung, and Blood Institute recommend hypertension trial design

Hypertension - New findings in hypertension described

Hypertension - Renal damage examined, role of calcitonin gene-related peptide defined

Hypertension - Results provide strong support for universal salt reduction in all hypertensives

Imaging - Brachytherapy planning tool streamlines prostate cancer treatments

Imaging - Late-enhancement MSCT is reliable in assessing MI infarct size

Imaging - Method for quantifying gated-SPECT images can measure LV volumes and EF

Imaging - Side-by-side quantitative polar representation may aid in complex assessment

Immunity - Cytomegalovirus disease analyzed, immune protective roles of T cells defined

Immunology - Modulation of T cell responses by TCR antagonism during infection reviewed

Immunology - Novel glycosphingolipids are CD1d-specific ligands for NKT cells

Immunology - Retinoids promote lipid efflux from stimulated macrophages

Implantable Cardiac Defibrillators - Outcomes have not improved with backup VVI pacing ICDs

Inflammation - Systemic inflammation analyzed, testicular interleukin-6 response clarified

Influenza Vaccine - Drug manufacturer to increase U.S. influenza vaccine capacity with new plant

Influenza Vaccine - Pharma company files for new indication of Tamiflu in Europe

Information Technology - Pharmacy franchisor to provide discounts on electronic prescribing transactions

Insomnia - Study of insomnia therapy in perimenopause-menopausal women shows improvement

Ischemia - Silent ischemia is linked with troponin elevation in high-cardiac-risk patients

Kidney Disease - Model demonstrates benefits of reducing CV risk patients with ESRD

Kidney Disease - Review discusses effects of renal replacement on arterial stiffness

Kidney Failure - Hepatitis C does not worsen liver disease in uremic hepatitis B patients

Kidney Failure - In many cases hepatitis C infection precedes end-stage renal disease

Kidney Transplantation - Campath-1H shows promise as rescue therapy for acute rejection

Kidneys - Fibrotic kidney cell transition studied, role of progenitor cells defined

Klebsiella Pneumoniae - Carbapenem-resistant K. pneumoniae rapidly spreading in New York City

Learning Disability - Racial differences in found in ADHD in young school-age children

Legal Issues - Pharma company reaches settlement with Connecticut on pricing litigation

Legionella Pneumophila - Sequence-based L. pneumophila typing epidemiologic concordant/discriminatory

Leucovorin - Capecitabine used as adjuvant treatment for stage III colon cancer

Leukemia - Combination of DAC with valproic acid showed antileukemic activity

Leukemia - Leukemic cell death induced by antithymocyte globulin

Leukemia Therapy - Effects of arsenic on tumor cell gene expression clarified

Lipid Research - Once-daily oral treatment for lipid disorders, cholesterol launched in U.S.

Lipid Studies - Lipids altered in very low-density lipoprotein subspecies in diabetes

Lipoproteins -  Weigela subsessilis coumarins examined, inhibited LDL oxidation defined

Lipoproteins - Soy protein supplementation is likely to diminish risk for CV disease

Lipoproteins - THP monocyte-derived macrophages demonstrate a preference for VLDL-1.

Liver Cancer - Cantide eradicates tumor growth in hepatocellular carcinoma models

Liver Cancer - Hepatocyte growth factor gene therapy impedes hepatoma cell proliferation

Liver Cancer - Human maid homologue useful marker protein in hepatocarcinogenesis

Liver Cancer - Studies describe new findings in liver cancer research

Liver Disease - Chemically treated mice model natural killer T cell liver injury

Lower Back Pain - Research shows low level heat wrap therapy helps low back pain

Lung Cancer - DNA methylation disturbances present a new way to target lung malignancies

Lymphoma - New research in the area of lymphoma detailed

Malaria -  Plasmodium falciparum cytokine responses are age dependent

Malaria - Pointers for malaria treatment from cancer chemotherapy detailed

Malaria - Researchers publish new studies and findings in the area of malaria

Malaria - TMP/SQX against P. gallinaceum infection prevents clinical malaria

Malaria Diagnosis - Malaria screening and treatment of refugees from Cambodia described

Malaria Therapy - Artemisinin-based therapy may not be the best treatment

Malaria Therapy - Researchers provide details of new studies and findings in the area of malaria therapy

Malaria Vaccines - Recent findings illuminate research in malaria vaccines

Market Analysis - Pharma competitive intelligence groups report to marketing

Marketing - Cancer drugs drive pharmaceutical success, claim marketing dollars

Marketing - Zonegran maker launches pharmaceutical marketing subsidiary in Sweden

Medicaid - Collaboration formed to educate Medicaid beneficiaries on options

Medical Devices - ISO certification issued for medical device company

Medical Devices - Medical device association applauds senate committee action

Medical Devices - Medical device company releases two new catheters

Medical Devices - Study on XLIF minimally disruptive spine surgery procedure presented

Medical Devices - sNDA filed for Biojector 200 in FUZEON administration

Medicare - Medicare proposes payment rates and policy changes for outpatient services

Medicare - Prescription drug benefit is on the way for patients with limited income

Medicare - Survey shows cholesterol tests of Medicare patients on the rise

Melanoma - Evodiamine induced human melanoma A375-S2 cell death

Menopause - Pharmaceutical company launches educational campaign about menopause for women

Mental Health - Aetna and GlaxoSmithKline cosponsor depression seminars for employers

Mental Health - Study finds animal assisted therapy can help troubled youth

Mergers & Acquisitions - Agreement reached for acquiring Greenwich Therapeutics, anti-cancer compounds

Mergers & Acquisitions - Bankruptcy court approves company's bid to acquire pain management portfolio

Mergers & Acquisitions - Biotech company exercises rights in Prima BioMed, Ltd.

Mergers & Acquisitions - European Commission clears Gillette merger

Mergers & Acquisitions - Japanese biopharmaceutical company to acquire Arakis for over $187 million

Mergers & Acquisitions - Manufacturer of Chinese herbal medicines completes merger with Child Vision, Inc

Mergers & Acquisitions - Oncology, acute care-focused company to acquire Guilford Pharmaceuticals, Inc.

Mergers & Acquisitions - Pharma company acquires GlycArt Biotechnology

Mergers & Acquisitions - Pharma company acquires QdotPharma

Mergers & Acquisitions - Pharma company to acquire OTC brand portfolio from Bristol-Myers Squibb

Mergers & Acquisitions - Pharma services company and Aptuit enter strategic partnership

Mergers & Acquisitions - Three Quintiles Transnational business units to be acquired

Metastatic Melanoma - Human trial of gene-based interleukin-2 with electroporation technology begun

Multiple Sclerosis - Clinical trial tests cholesterol drug to minimize multiple sclerosis

Multiple Sclerosis - Foundation raises first $5 million for multiple sclerosis research

Multiple Sclerosis - Two-year study of Tysabri with Avenox reinforces efficacy in multiple sclerosis

Mycobacterium Avium - Culture with molecular confirmation rapid/sensitive for M. avium diagnosis

Mycobacterium Avium - Identified M. avium gene affects invasion of the intestinal epithelium

Mycobacterium Bovis -  Mycobacterium bovis can persist in farm environment outside of its hosts

Nanotechnology - Antibiotic development program uses nanoparticle delivery platform

Nanotechnology - Life Sciences company announces research findings about nanobacteria

Nasal Cancer - Loss of caspase 3 activation in neoplastic cells predicted rapid fatal outcome

Neolignans - Neolignans demonstrated cytotoxicity towards human cancer cell lines

Neurogenesis - Chronic alcohol exposure reduces hippocampal neurogenesis of newborn neurons

Neurogenesis - Neuropathy target esterase activity needed for optimal neurite initiation rate

Neuropathy - Diabetic nerve therapy shows "striking" results

Neuropathy - Transthyretin complex studied, association with amyloid inhibitor clarified

Neuroprotection - Progesterone neuroprotection in spinal cord trauma involves BDNR upregulation

Neuroscience - Adult stem cell breakthrough for neurodegenerative diseases reported

Neuroscience - Ras activation increases synapse formation in the neocortex

Nicotine Vaccine - Nicotine-specific antibodies reduce nicotine distribution to brain

Nosocomial Infections - Shower filter helps protect against waterborne pathogens

Obesity Therapy - Full-weight dose chemotherapy improves outcomes in obese women with cancer

Obesity Therapy - Treatment boosts the stomach's "full" signal

Obesity and Diabetes - Studies advance knowledge in obesity and diabetes research

Obstetrics - Researchers' work adds to obstetrics body of knowledge

Obstetrics - Sengstaken-Blakemore intrauterine tamponade is indicated for hemorrhage

Oncogenesis - Hepatitis C may trigger B-cell disorders through CD81 and E2 interaction

Oncology - Data advance knowledge in oncology research

Oncology - Genetic patterns emerge in colorectal cancers

Oncology - Growth factor independent-1 repression of CYP27B1 promotes prostate cancer

Oncology - New thalidomide analogs direct antiangiogenic activity at multiple myeloma

Oncology - PIK3CA mutations foster cancer cell growth and invasion

Oncology - VEGF governs intussusceptive microvascular growth in primary melanoma

Ophthalmology - Antisense constructs abate excess lens epithelial cell proliferation

Ophthalmology - Researchers' findings advance ophthalmology research

Ophthalmology - Triamcinolone temporarily improves vision in eyes with exudative disease

Ophthalmology - VEGF transgenic mice develop retinal vasculopathy

Oral Health - Cimetidine rinse enhances gingival crevicular neutrophil function

Oral Health - Interleukin-1 beta gene polymorphism associates with chronic periodontitis

Oral Health - Microbial vesicles end cell growth and angiogenesis to cause periodontitis

Orthopedics - Prx1 homeobox gene isoforms play opposing roles in chondrogenesis

Osteoporosis - Phase I clinical trial for osteoporosis complete

Osteoporosis - Recent findings in osteoporosis provide new insights

Osteoporosis - Study investigates women's preferences for preventing osteoporosis

Ovarian Adenocarcinoma - CPT-11 and mitomycin C treated ovarian clear cell adenocarcinoma

Ovarian Cancer - Genes involved in chemotherapy resistance identified

Ovarian Cancer - K252a inhibited proliferation of ovarian cancer cells by upregulating p21(WAF1)

Ovarian Cancer - Patients unlikely to benefit from further chemotherapy identified

Ovarian Cancer - Plasmacytoid dendritic cells induce CD8+ cells in ovarian cancer

Ovarian Cancer Therapy - Antisurvivin oligonucleotides generate apoptosis in ovarian cancer cells

Pain Management - Experimental therapy with cannabinoids may be justified in some MS cases

Pain Management - Oral analgesic protocol improved pain control for patients with cancer

Pain Management - Sexual pain syndrome has a complex etiology

Pain Management - U.S. NIH awards $197,000 grant to develop drug candidate for neuropathic pain

Pancreatic Cancer - Activation of RaIA deemed critical for Ras-induced tumorigenesis of human cells

Pancreatic Islets - Angiotensin receptor inhibition improves insulin secretion in islets

Parkinson Disease - Drug used to treat PD may be beneficial in treating fibromyalgia

Parkinson Disease - Pharmaceutical company completes Parkinson disease trial

Patents - Biotech company issued patent for method of producing infectious reovirus

Patents - European patent issued for target discovery technology

Patents - Pharma company issued patent for lingual spray technology

Patents - U.S. patent granted for asthma treatment

Patient Safety - Guardlid launched as new child-resistant pharmaceutical packaging solution

Pediatric Immunization - Premature infants should be monitored when given combination vaccines

Pediatric Peritoneal Dialysis - Peritoneal dialysis is safe in children after cardiopulmonary bypass

Pediatrics - Infant feeding patterns and risks of death investigated

Personnel - August Watanabe, MD, named nonexecutive chair of drug discovery company board

Personnel - Barry A. Labinger named executive VP and chief commercial officer

Personnel - Berkeley pharmacy names Kathi Lentzsch new CEO

Personnel - Biomedical company appoints Ronald W. Mink chief science officer

Personnel - Biopharma company appoints member to board

Personnel - Biopharmaceutical company establishes sickle cell advisory board

Personnel - Biotech company names Jeffrey Skulsky VP, MIS

Personnel - Biotech company strengthens finance, clinical, quality management team

Personnel - Biotech group names chairman, board members for 2005-2006

Personnel - Drug discovery company appoints new scientific advisory board

Personnel - Eve Slater, Kevin Reilly named to board of infection-focused biopharm company

Personnel - Generic pharma company announces board member resignations

Personnel - Healthcare company announces new member of board of directors

Personnel - Imaging company names Dr. Neil Dey VP of business development, marketing

Personnel - James L. Vincent named director at biopharmaceutical company

Personnel - John M. Taylor III appointed to government affairs staff at pharma firm

Personnel - Joseph P. Campanelli named chairman of the board by academic medical institution

Personnel - Kimberly Popovits joins board of directors

Personnel - Kiyotaka Fujii named president, CEO by provider to healthcare, pharma industries

Personnel - Michael A. Fauman, MD, PhD, appointed to APA psychiatric diagnosis committee

Personnel - Ophthalmic products maker names Mark H. Karsch CFO

Personnel - Pharma company appoints general counsel

Personnel - Pharma company transitions board chair position

Personnel - Pharmaceutical company adds Lynn Smiley as chief medical officer

Personnel - Pharmaceutical company announces management appointments

Personnel - Pharmaceutical company appoints William Peters to board

Personnel - Pharmaceutical company strengthens its sales and marketing team

Personnel - Pharmaceutical firm appoints Carol Raphael to board of directors

Personnel - Richard J. Welter, PhD, named VP business development by pharmaceutical company

Personnel - Sue Bailey joins scientific advisory board of recombinant human enzymes company

Personnel - Supplier of healthcare personnel retains new professionals

Personnel - Surgeons' group selects president-elect

Pharmaceutical Research - Biologic treatments help improve quality of life for psoriasis patients

Pharmaceutical Research - Early access program launched for new line of genotyping assays

Pharmaceutical Research - Study examines pharma product lifecycle management

Phosphatase - Phosphatase regulation studied, role of a phosphate kinase defined

Physiology - Pronephric glomus analyzed, nephrin expression and morphogenesis clarified

Plasmodium Berghei - Thalidomide influences macrophage function/increases P. berghei survival

Plasmodium Falciparum -  P. falciparum FK506 has drug-independent calcineurin-inhibitory activity

Pneumocystis Carinii -  P. carinii is the most common finding in lung biopsies of HIV patients

Pollution - Meta-analysis reports association between ozone and mortality

Pontiac Fever - Pontiac fever/respiratory distress outbreak in sugar-beet processing plant

Preventive Medicine - Single-pill amlodipine/atorvastatin reduces both BP and cholesterol

Product Licensing - Companies ink PER.C6 licensing agreement with Symphogen

Product Licensing - Generic HIV/AIDS efavirenz license granted to African manufacturer

Product Licensing - License granted to fundamental RNAi patents

Product Licensing - Licensing agreement signed for drug delivery technology for drug eluting stents

Product Licensing - Life science company offering tools to contract research organizations

Product Licensing - Life sciences company licenses fundamental RNAi patent estate from Alnylam

Product Licensing - PQB company signs agreement with CNRS

Prognostics - Outcome of postoperative radiation therapy for prostate carcinoma surveyed

Prostate Cancer - Combination hormone/vaccine therapy may benefit patients whose disease returns

Prostate Cancer - New class of inhibitors of 2-AG hydrolysis identified

Prostate Cancer - Pharma company initiates phase I study of RC-8800 for prostate cancer

Prostate Cancer - Phase 2 clinical trials of OGX-011 for prostate cancer initiated

Prostate Cancer - Sca-1 enriches for prostate-regenerating cells that initiate tumorigenesis

Prostate Cancer - Supply agreement announced Prospera palladium-103 prostate brachytherapy

Prostate Cancer - Symposium on high intensity focused ultrasound treatment for prostate cancer

Prostatectomy - Chance of achieving optimal outcomes after radical prostatectomy described

Proteomics -  Hansenula polymorpha manufactures recombinant human endostatin

Proteomics - A new two-step method simplifies recombinant alpha-synuclein production

Proteomics - Aging skeletal muscle examined, protein nitration analyzed

Proteomics - Avian cells produce recombinant human interleukin-11

Proteomics - Compounds could lead to agents with hypotensive and lipid-lowering properties

Proteomics - Findings in proteomics provide new insights

Proteomics - Key endoglin isoforms have contrasting effects on tumor development

Proteomics - The chemokine ligand CCL23 amplifies endothelial cell migration

Pseudomonas Aeruginosa -  Pseudomonas aeruginosa lectin LecB involved in biofilm formation

Psoriasis - American version of PSORIQoL test developed

Pulmonary Arterial Hypertension - Effect of bosentan treatment on surrogate markers determined

Pulmonary Hypertension - Sildenafil may improve hemodynamics in children with pulmonary HT

Q Fever Outbreaks - Q fever outbreak in urban area suggests presence of nearby livestock facility

RNA Research - Company to explore uses for new ribonuclease drug candidate

RNA Research - Papers identify human kinases involved in endocytosis

Radiation Therapy - Patients with early esophageal squamous cell carcinoma treated with radiation

Renal Disease - Decreased angiotensin II type-1 receptor lowers proteinuria in rats

Respiratory Care - Airway lavage modeled, nature of reduction in lung edema clarified

Retinopathy - Findings advance knowledge in retinopathy research

Rheumatic Heart Disease - New vessel growth contributes to rheumatic valve calcification

SARS - SARS Neugene antisense studies published

SARS - SARS outbreaks in Taiwan originated from multiple sources

SARS Coronavirus - Researchers' data advance SARS coronavirus research

SARS Coronavirus - Rolling circle amplification is rapid/sensitive for SARS coronavirus detection

SARS Vaccines - Reports describe recent advances in SARS vaccines research

Salmonella Typhi - Extra-intestinal complications can occur with Salmonella typhi infection

Sarcomas - Adult-type soft tissue sarcomas discovered in pediatric-age patients

Schizophrenia - Schizophrenia model analyzed, effect of Chakragati mutants clarified

Sexual & Reproductive Health - National institute accepts clinical trial of female sexual dysfunction treatment

Sexually Transmitted Disease - Treatment can be effectively administered by sex partners

Shingles - What is the best treatment for post-herpetic neuralgia?

Skin Cancer - Approaches to medical treatment of basal cell carcinoma discussed at conference

Smallpox Vaccine - Integral equation model for control of smallpox outbreak developed

Smallpox Vaccine - Phase 1/2 study of attenuated smallpox vaccine candidate completes enrollment

Sperm Capacitation - Sperm capacitation studied, nature of protein modulation defined

Statins - Innovative approaches are needed to promote statin use for eligible patients

Stem Cell Research - Biopharm company gets $35 million to create mouse embryonic stem cell library

Stem Cell Research - Cancer research association makes statement supporting stem cell biology

Stem Cell Research - HSC mobilization speeds renal function recovery independent of SC contribution

Stem Cell Research - Hepatocyte growth factor modulates matrix turnover in glomeruli

Stem Cell Research - Laminin-5 induces osteogenic gene expression in MSCs through ERK-dependent path

Stem Cell Research - Monocyte-derived Neohepatocytes developed for autologous cell therapy

Stem Cell Research - Nonviral vectors fuel RNA interference in human mesenchymal stem cells

Stem Cell Research - P38alpha/beta MAPK acts as molecular switch to activate quiescent satellite cell

Stem Cell Research - Small hepatocytes differentiate and re-express constitutive cytochrome P450s

Stem Cell Research - Study: ADCs will engraft in injured heart muscle after heart attack-like injury

Stem Cell Research - T-cells generated by lymph node resident progenitor cells

Stem Cell Research - U.S. bone graft trial expanded to include University of Nebraska Medical Center

Stem Cell Transplantation - MSCs may be used for GVHD prophylaxis and for treatment of severe acute GVHD

Stem Cell Transplantation - New findings in the area of stem cell transplantation detailed

Stem Cell Transplantation - Transplant of dHGF-cultured hepatocytes prolongs survival of acute liver failure

Stomach Cancer - From thousands of genes to a single compelling new target

Streptococcus Pneumoniae - Clone disseminate of rifampin-resistant S. pneumoniae found in HIV patients

Stroke - AF was present in more than 20% of patients with first-ever stroke

Stroke - Monkey model of thrombotic middle cerebral artery occlusion developed

Systemic Lupus Erythematosus - Lupus patients have abnormally high frequencies of EBV-infected cells

Systemic Lupus Erythematosus - Phase I study of 57-57 for Systemic Lupus Erythematosus complete

Systemic Lupus Erythematosus - Review examines new modalities for assessment of vascular health in SLE patients

Testicular Cancer - Single dose of chemotherapy is as effective as radiotherapy

Tissue Engineering - Researchers detail new studies and findings in the area of tissue engineering

Tobacco Use - Enrollment completed in study of vaccine to prevent and treat nicotine addiction

Tobacco Use - Mice lacking alpha 7 nicotinic receptors show no changes in nicotine tolerance

Tobacco Use - Single cigarette can interfere with cardiac turnover of catecholamines

Tourette Syndrome - Metoclopramide shows promise for treatment of young patients

Toxicology - Dioxin exposure reduces endothelial cell response to angiogenic stimuli

Toxicology - Oral benzene exposure alters gene expression in rodent livers

Toxoplasmosis - Cross-reactive antigens from N. caninum & T. gondii used for vaccines

Transplant Medicine - Bile duct necrosis impedes liver graft survival

Transplant Medicine - Hepatitis C infection compromises liver re-transplantation outcomes

Transplant Medicine - Hepatitis C viremia increases immediately after renal transplantation

Transplant Medicine - New data illuminates research in transplant medicine

Transplant Medicine - New finding may aid adult stem cell collection

Transporters - Apical bile acid transporter examined, role of cysteines clarified

Tuberculosis - Humoral response against LMW antigens important for detection of latent TB

Tuberculosis - Mononeuropathy multiplex/chylothorax early manifestations of pulmonary TB

Tuberculosis - Widespread tuberculosis preventive therapy would impact morbidity and mortality

Tuberculosis - cAMP-mediated gene regulation detected in tuberculosis complex mycobacteria

Tuberculosis Vaccine - Phase I clinical trials proposed for candidate live mycobacterial vaccines

Type 1 Diabetes - Intellectual property agreement signed for anti-CD3

Type 2 Diabetes - Pharma company initiates trial of PSN357

Type 2 Diabetes - Study evaluating drug impact on type 2 diabetes patient treatment completed

Type 2 Diabetes - Study reaffirms Diachrome improves cardiovascular disease risk in diabetes

Ulcers - Famotidine and omeprazole prevented bleeding after endoscopic mucosal resection

Umbilical Cord Blood Transplantation - UCBT for heatstroke resuscitation reduces shock and ischemic injury

Urinary Incontinence - Botulinum toxin type A reduces neurogenic detrusor overactivity

Urology - Company updates U.S. FDA pre-market approval submission for incontinence implant

Urology - VEGF antisense therapy augments bladder cancer chemotherapy

Vaccines -  Francisella tularensis vaccine studied, proteomic analysis reported

Vascular Surgery - Novel rat model of microarterial traction developed

Vector Development - Improved inducible lentivirus vectors gain tighter transgene expression

Vector Development - PLGA microspheres with decoy oligonucleotide block nuclear factor-kappa B

Venous Ulcers - FDA approves protocol and initiation of confirmatory trial of OrCel

Ventilator-Associated Pneumonia - Impact of ARDS on clinical outcome determined

Vibrio Harveyi - Monoclonal antibodies developed for Vibrio harveyi detection

Virology - Hepatitis C RNA is unchanged in HIV-coinfected patients given interleukin 2

Virology - Reports add new data to virology research

Virology - The hypervariable region 1 of hepatitis C may establish viral persistence

Wound Healing - Fibrin sealant accomplishes hemostasis following partial liver resection