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Susan Hasty, Publisher
Table of Contents . . . August 26th, 2005
Non-Subscriber - Summaries Only
Related Areas: Other Issues in Drug Week | Other Publications
Clinical Trials - Recombinant protein HIV vaccine candidate to be tested in clinical trials
Drug Development - Results reported from pediatric Amoxicillin PULSYS phase III trial
Drug Development - U.S. FDA issues approvable letter for Entereg (alvimopan)
Obsessive Compulsive Disorder - Medication eases obsessive-compulsive symptoms
Prostate Cancer - Phase III Trial: Provenge extends survival in advanced prostate cancer patients
Acetylcholine Receptors - Muscarinic acetylcholine receptor studied, basolateral sorting signal defined
Acne - TAZORAC compliance program launched for teens
Addiction Medicine - Brief access to sweets prevents cocaine-seeking relapse in rats
Addiction Medicine - Daily marijuana use exacerbates chronic hepatitis C-related liver fibrosis
Adipose Tissue - Rosiglitazone upregulates lipases in brown adipocytes
Adverse Drug Reaction - Advance liver disease hampers tolerance to hepatitis C combination therapy
Cancer Vaccines - Researchers publish new studies and findings in the area of cancer vaccines
Adverse Drug Reaction - Automated dispensing system improves ADR reporting
Adverse Drug Reaction - Importance of reporting suspected drug reactions emphasized
Age Related Macular Degeneration - Choroidal neovascularization therapies render similar outcomes
Alcohol Use - Chronic ethanol consumption may contribute to development of restenosis
Allergy & Immunology - Allegra extended release tablets available for allergy sufferers
Alternative Medicine - Capillary zone electrophoresis assay devised for goldenseal extract analysis
Diagnostics - Recent studies add new data to diagnostics research
Alzheimer Disease - Amyloid-mediated endothelial damage studied, lack of estrogen protection shown
Alzheimer Disease - Anti-inflammatory function of AD drugs revealed
Alzheimer Disease - ELISA developed for amino-terminally truncated beta-amyloid peptide quantitation
Alzheimer Disease - Enrollment begins in additional phase IIa studies with AMPAKINE CX717
Alzheimer Disease - Hope for brain disease blossoms
Alzheimer Disease - Novel assays facilitate characterization of BACE-1 inhibitors
Gastroenterology - Recent studies add new data to gastroenterology research
Alzheimer Disease - Study suggesting procaine as exerting neuroprotective properties published
Amyotrophic Lateral Sclerosis - Gene therapy company awarded grant for evaluation of ALS treatment
Amyotrophic Lateral Sclerosis - Intrathecal BDNF doesn't improve autonomic function
Anal Pain - Nicorandil implicated in idiopathic anal ulceration
Analgesia - Ultralow-dose naltrexone enhances oxycodone analgesia
Anemia - Outcome of clinical analysis of chronic benzene poisoning revealed
Gastroenterology - Reports add new data to gastroenterology research
Anesthesia - Study shows effect of multiple opoids on open-heart surgery patients
Angina - Palpation of spine and thorax were used to screen chest pain patients
Angiology - Coronary retrograde perfusion may be technique for myocardial ischemia
Angiology - Laser perforation mobilizes matrix graft adaptation in treated arteries
Angiology - Needle-guided ultrasound enhances cannulation success
Angiology - Researchers publish new studies and findings in the area of angiology
Malaria - Researchers detail new studies and findings in the area of malaria
Angiotensin - ATPase activity analyzed, angiotensin modulation revealed
Angiotensin Converting Enzyme - Assay determines plasma and tissue ACE activity
Anorexia - Megestrol phase II proof-of-concept study results reported
Anthrax - Complement depletion renders mice sensitive to Bacillus anthracis
Anthrax - Critical step traced in anthrax infection
Anti-Platelet Therapy - Point-of-care monitoring system developed
Neuroscience - Recent findings in neuroscience described
Antiarrhythmic Drugs - AF-induced remodeling did not alter flecainide action on conduction
Antibacterial Agents - Data on healthy subjects provide patient target attainment for antibacterials
Antibacterial Agents - Phage therapy examined as treatment option for diarrheal disease
Antibacterial Agents - Pharma company reports results of aminomethylcyclines trial
Antibiotic Resistant Bacteria - Metallo-beta-lactamase-resistant bacteria is an emerging epidemic
Antibiotics - Bacillus subtilis protein inhibition raises antibiotic susceptibility
Neuroscience - Research in neuroscience provides new insights
Antibiotics - Cytotoxic constituents of the fruit body of Daedalea dickisii studied
Antibiotics - Link between antibiotic exposure and breast cancer in New Zealand evaluated
Anticancer Agents - Anticancer agent for hypoxic cells discovered
Anticancer Drug - Deguelin enhances leukemia cell chemosensitivity with active PI3K/AKT pathway
Antimicrobial Resistance - Survivability of vancomycin-resistant enterococci examined
Antimicrobial Therapy - Aminoglycoside extended interval dosing safe and effective for neonates
Oncology - Researchers describe findings in oncology studies
Antimicrobials - Antimicrobial peptides analyzed, polysaccharide interaction clarified
Antimicrobials - Peptides may attenuate lung damage associated with cystic fibrosis
Antioxidants - Bioactivity and protective effects of natural carotenoids identified
Antioxidants - Findings advance knowledge in antioxidants research
Antioxidants - Phycocyanin antioxidant activity studied, affecting factors clarified
Antiplatelet Drugs - Alterations of receptor gene may be a mechanism for clopidogrel failure
Oncology - Researchers' work adds to oncology body of knowledge
Antiplatelet Drugs - Review discusses clopidogrel guidelines based on clinical trial data
Antiproliferative Activity - Hopane and oleanane glycosides exhibited antiproliferative activity
Antituberculosis Therapy - Some antituberculous drugs alone or in combination enhance PMN functions
Aphthous Ulceration - Aphtheal effective at onset on prodromal RAU symptoms
Apoptosis - Apoptosis induced by Eurycoma longifolia Jack extracts
Apoptosis - Apoptosis signal-regulating kinase examined, regulation defined
Oncology - Studies add new findings to oncology body of knowledge
Apoptosis - Cas II-gly induced apoptosis in glioma C6 cells in vitro and in vivo
Apoptosis - Enterolactone induced apoptosis and inhibited growth of colon cancer cells
Apoptosis - Grifolin inhibited tumor cell growth by inducing apoptosis in vitro
Apoptosis - Role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2
Arteriosclerosis - Long-term treatment with nicorandil may prevent cardiovascular events
Arthritis - Early trial results of tgAAC94 in patients with inflammatory arthritis reported
Proteomics - Researchers report details of new studies and findings in the area of proteomics
Arthritis - Inflammation and tissue destruction studied, interferon homeostatic role shown
Arthritis Therapy - Yeast glucan derivative has antioxidant activity in rat model
Asthma - New school policy guide issued to help manage children's asthma
Asthma - Omalizumab add-on therapy reduced severe allergic asthma attacks in 7 studies
Astrocytoma - Magnetic resonance spectroscopy of oligodendroglial tumors aided cancer staging
Atherosclerosis - Phosphatidylethanol boosts smooth muscle cell production of VEGF
Transplant Medicine - Reports add new data to transplant medicine research
Atherosclerosis Risk Factors - Cholesterol efflux to plasma from diabetic patients is enhanced
Attention Deficit Hyperactivity Disorder - Amended NDA for treatment of pediatric ADHD patients resubmitted to FDA
Attention Deficit Hyperactivity Disorder - FDA expands indication for ADDERALL XR to include adolescents aged 13-17
Autoimmune Diseases - Cirrhosis forecasts a poor prognosis for patients with autoimmune hepatitis
Autoimmune Diseases - Human monoclonal autoantibody creates murine autoimmune hepatitis models
Awards - $1.5 million pledged to Runyon foundation accelerate clinical cancer research
Virology - Findings advance knowledge in virology research
Awards - Stephen C. Harrison wins Bristol-Myers Squibb infectious diseases research award
Bacterial Meningitis - Awareness of disease mechanisms leads to better therapies
Barrett Adenocarcinoma - MAPK and PI3K inhibition reduced proliferation of Barrett adenocarcinoma
Bartonella - Bartonella causes a broad number of infectious diseases
Biomedical Engineering - Hollow fiber assays assess anti-neovascular therapy
Biomedical Engineering - Scientists confirm relationship between inflammatory response and glucose levels
Virology - Researchers' findings advance virology research
Biotechnology - Pharma announces senior management changes
Bioterrorism - Agreement inked with Dow for BT-VACC for botulinum toxin poisoning
Blood Banking - Controlled-rate freezing used to cryopreserve embryonic stem cells
Brain Cancer - Findings describe new data in brain cancer research
Brain Cancer - VEGF helps transplanted neural stem cells seek brain tumors
Breast Cancer - Gene found in 90% of breast cancers may be cancer vaccine target
Breast Cancer - Lymph-node micrometastases worsens outcomes for breast cancer patients
Breast Cancer - Mechanisms of omega-3 fatty acid-induced growth inhibition analyzed
Breast Cancer - New treatment for breast cancer and choroidal metastasis described
Breast Cancer - Patterns of toxicity evaluated in older patients receiving adjuvant chemotherapy
Breast Cancer - RALT gene loss impedes the efficacy of HER-2 inhibitor
Breast Cancer - Researchers report details of new studies and findings in the area of breast cancer
Breast Cancer - Traumatic stress, perceived global stress, and life predicted quality of life
Business & Finance - Biotechnologies research company reports second quarter 2005 financial results
Business & Finance - Company announces adoption of share repurchase program
Business & Finance - Cord blood banking company reports strong growth
Business & Finance - Diagnostic testing company reports second quarter 2005 results
Business & Finance - Diagnostic tests company projects first quarter profit
Business & Finance - Drug development company reports second quarter 2005 results
Business & Finance - Drug discovery and development company reports financial results
Business & Finance - Pharma company announces second quarter 2005 results
Business & Finance - Pharma company reports second quarter and 6 month 2005 financial results
Business & Finance - Pharmaceutical company reports second quarter operational and financial results
Business & Finance - Pharmaceutical firm files for Chapter 11 reorganization
Business & Finance - Respiratory market distributor announced financial results
Business Update - Antiviral drug discovery and development company relocates to New Jersey
Business Update - Biopharma company announces new executive share ownership guidelines
Business Update - Biotech company opens laboratory facility
Business Update - Biotech firm retains Financial Dynamics as communications advisor
Business Update - Cancer-focused pharmaceutical company included in new NASDAQ Health Care Index
Business Update - Companies complete $525M purchase from Emory of emtricitabine royalty interest
Business Update - Company announces FDA nonapprovable letter on sNDA for Namenda for mild AD
Business Update - Company announces the launch of Exactacain
Business Update - Company to divest capital equipment business; delays reporting Q2 earnings
Business Update - DNA-focused company achieves "important milestones" in second quarter
Business Update - European Union's CHMP adopts positive opinion for NOXAFIL
Business Update - HealthTronics announces strong second quarter results
Business Update - Human Genome Sciences announces financial results for second quarter of 2005
Business Update - I-Flow second quarter loss narrowed to $0.03 per share
Business Update - Introgen Therapeutics announces strategic investment in UK-Based SR Pharma
Business Update - Pharma company enters distribution and supply agreement for leflunomide tablets
Business Update - Pharmaceutical firm announces new lab, office space
Business Update - Procter & Gamble enters agreement with pharma discovery provider
Business Update - Programs launched for emergency biorepository storage, transition
Business Update - Research shows economic incentives can drive hospital quality improvement
Business Update - Therapeutic apheresis company enters agreement with Advanced Cell & Gene Therapy
Business Update - U.S. marketing rights to eptifibatide injection acquired by healthcare company
Cancer Research - Monoclonal antibody D2-40 helps distinguish HB from CRCC
Cancer Risk Factors - Higher cancer risk found in progeny of mice exposed to X-rays before conception
Cancer Risk Factors - KLF6 gene mutations may encourage gastric cancer progression
Cancer Therapy - Antibody to junctional adhesion molecule-C blocks angiogenesis and tumor growth
Cancer Therapy - Cetuximab arrests hypoxia-inducible factor-1 alpha expression to block VEGF
Cancer Therapy - Chemokine CXCL11 targets tumors but leaves angiogenesis intact
Cancer Therapy - Company initiates phase I clinical trial for anticancer compound XL820
Cancer Therapy - Deltec and Groshong central venous access port systems compared
Cancer Therapy - Drug candidates that counter resistance to Gleevec, Iressa, Tarceva identified
Cancer Therapy - Hydrocortisone may play a key role in cancer immunotherapy
Cancer Therapy - Novel boron-containing carbonic anhydrase inhibitors synthesized
Cancer Therapy - Partnership formed to develop and commercialize new oral chemotherapy
Cancer Therapy - Patient enrollment completed in REOLYSIN clinical trial for cancer treatment
Cancer Treatments - Abducens nerve palsy and Horner syndrome caused by metastatic tumor in sinus
Cancer Treatments - Changes of thymidine kinase helped monitor effects of chemotherapy
Cancer Treatments - IL-15 serum levels elevated in workers exposed to chemotherapeutic agents
Cancer Treatments - Imaging of soft tissue sarcomas advised
Cancer Treatments - Neoadjuvant and adjuvant therapy for extremity soft tissue sarcomas discussed
Cancer Treatments - Olanzapine prevented chemotherapy-induced nausea and vomiting
Cancer Treatments - Possible antitumor ribonucleoside developed
Cancer Treatments - Quality of life during palliative chemotherapy for solid cancer kept intact
Cancer Treatments - Radical radiotherapy with or without chemotherapy compared in NSCLC patients
Cancer Vaccine - Chemosensitization of carcinoma cells enhances vaccine cytotoxicity
Cancer Vaccines - Researchers provide details of new studies and findings in the area of cancer vaccines
Cardiac Drug Therapy - Insufficient data exist to allow selection of specific inotropic agents
Cardiac Drug Therapy - Study examined cerivastatin/nifedipine in injured coronary arteries
Cardiac Therapy - COPD and reversibility should be ascertained before withholding beta-blockers
Cardiography - Magnetocardiography can be useful to improve diagnostic accuracy
Cardiology - CRP discriminates poorly between people with/without coronary disease
Cardiology - Cardiology must embrace preventive interventions that forestall future events
Cardiology - Cardiostimulants increase activity of calcineurin in the heart
Cardiology - Drug blocking the actions of aldosterone beneficial in heart failure treatment
Cardiology - ECG is the most important diagnostic test for aortic regurgitation
Cardiology - Human cytomegalovirus activates signals that trigger neointimal proliferation
Cardiology - MI patients with high BMI were less likely to have invasive coronary procedures
Cardiology - Model provides method to assess changes in cardiac electrophysiology
Cardiology - Nitric oxide synthase ameliorates cardiomyopathy in hearts lacking dystrophin
Cardiology - Research add new data to cardiology body of knowledge
Cardiology - Study compares sirolimus-eluting stents with vascular brachytherapy
Cardiology - Study examined cardiac actions of urotensin II
Cardiology - Study examined role of caveolae in protein kinase A activation
Cardioprotection - Study examined effects of adenosine kinase inhibition on infarction
Cardioprotection - Study examined effects of flavonoid treatment on endothelial functions
Cardiopulmonary Bypass - ACT system increased the heparin dose required to exceed target ACT
Cardiovascular Disease - Experimental studies suggest NAD(P)H oxidase activates vascular remodeling
Cardiovascular Disease - Method measures all known plasma forms of vitamins B6 and B2
Cardiovascular Drug Therapy - Inhibition was maintained more effectively with tirofiban than eptifibatide
Cardiovascular Research - 2-methoxyestradiol exerts renal and CV protective effects
Cardiovascular Research - Deficiency of eNOS is compensated in coronary circulation, not in aorta
Cardiovascular Research - Detrimental effect of receptor stimulation was induced by dobutamine
Cardiovascular Research - SR-BI KO/ApoeR61 h/h mice may contribute to understanding of CHD
Cardiovascular Research - Study examined mechanisms of mineralocorticoid receptor antagonism
Cardiovascular Research - Study examined the effect of amiodarone on CV reflexes
Cataract Surgery - Novel vancomycin insert shows promise for endophthalmitis prevention
Cataracts - Ophthalmology company's second quarter sales increase 12.8%
Cell Biology - Malaria mechanism revealed
Cell Biology - Stressed environments change the expression of human chloride channel genes
Central Nervous System - Galanin receptor examined, distribution in central nervous system defined
Childhood Cancer - Management strategies for asymptomatic cardiac damage discussed
Cholera - Positive preliminary results from clinical trial of cholera vaccine reported
Chronic Hepatitis B - Liver disease severity beats hepatitis B genotype as a cause of drug resistance
Chronic Hepatitis C - Hepatitis C genotype 4 is highly insensitive to pegylated interferon
Chronic Liver Disease - Apparent diffusion coefficient measurements help stage liver fibrosis
Chronic Liver Disease - Hepatitis B cirrhosis-related complications arise despite low DNA levels
Chronic Liver Disease - Ultrasound biopsy findings correspond with liver histology
Chronic Lymphocytic Leukemia - Trial begins for telomerase inhibitor drug GRN163L in patients with CLL
Cidofovir - Cidofovir treated recurrent respiratory papillomatosis
Cisplatin - Cisplatin, gemcitabine and treosulfan used to treat metastatic uveal melanoma
Clinical Studies - Single-ingredient compared to combination cream in melasma treatment
Clinical Trials - Cancer-focused company to downsize, focus on taxane compound clinical program
Clinical Trials - Eight-week doxycycline course safe/effective for lymphatic filariasis
Clinical Trials - Eye-disease-focused company reports Q2 revenue of $57.1 million
Clinical Trials - InKine announces the acceptance for filing of its new drug application (NDA)
Clinical Trials - Prasugrel and clopidogrel both resulted in low bleeding rates in PCI patients
Coagulation Therapy - Brand-name and generic warfarin have equivalent performance
Collaborations - Agreement signed to create monoclonal antibodies with improved efficacy
Collaborations - Alliance to phenotype E. coli genome expanded
Collaborations - Collaboration, licensing agreement signed to develop anti-inflammatory agents
Collaborations - Companies ink clinical data management solutions agreement
Collaborations - Compound library agreement signed with Evotec
Collaborations - Deal signed with Boehringer Ingelheim for biomarkers
Collaborations - Deal signed with vaccine developer
Collaborations - Development deal signed for cancer biomarkers
Collaborations - Financing secured for development of BEMA Fentanyl
Collaborations - Hurel Corp. and Johnson & Johnson enter into joint scientific collaboration
Collaborations - Igeneon and Celltrion announce commercialization and manufacturing agreement
Collaborations - Joint ophthalmology research project focuses on nitric oxide-donating compounds
Collaborations - License granted to develop RNAi therapeutics against TNF-alpha
Collaborations - Licensing deal signed for oncology drug eniluracil
Colorectal Cancer - CONFIRM 2 trial disclosure data released
Complementary & Alternative Medicine - Many body-conscious teens use supplements to improve physique
Complementary & Alternative Medicine - Monocytic leukemia cells analyzed, G1 phase arrest reported
Complementary & Alternative Medicine - Orexin A examined, effects on olfactory bulb and odor responsiveness defined
Complementary & Alternative Medicine - ShimodaAtlantic launches new vertigo drug: Verticil
Congenital Heart Disease - Study examined prescription, tolerance, efficacy of prostaglandin E1
Contraception - NDA filed with U.S. FDA for oral contraceptive with uninterrupted dosing regimen
Coronary Artery Bypass - New anti-blood-thinning drug not as safe as protamine
Critical Care Medicine - Test to rule out heart attack could reduce hospital admissions
Crohn Disease - MAP specific IS900 DNA is a predominant feature of Crohn disease
Cryptococcus Neoformans - CD8+ T cell function independent of CD4+ T cells in C. neoformans infection
Cryptosporidiosis - Unique endemicity of cryptosporidiosis in children in Kuwait described
Cyclooxygenase - FC-77 inhibited inflammatory response in RAW 264.7 macrophages
Cytomegalovirus - CMV-specific cytotoxic T cells expanded using recombinant polyepitope
Depression Therapy - Adjunctive bright light effective in non-seasonal major depression
Dermatology - LYVE-1 antibody detects melanoma cells in the lymphatic system
Diabetes Complications - Serum prorenin levels rise as proliferative diabetic retinopathy forms
Diabetes Risk Factors - Atypical antipsychotic drugs and diabetes examined
Diabetes Therapy - Benidipine improves endothelial dysfunction in diabetic patients
Diabetes Therapy - Metformin does not reduce blood pressure in type 2 diabetes
Diabetes Therapy - Researchers detail new studies and findings in the area of diabetes therapy
Diagnostics - Findings advance knowledge in diagnostics research
Diagnostics - Minisequencing and mass spectrometry uncover hepatitis C genotypes
Diagnostics - Xenograft models link genes to breast cancer metastasis
Diagnostics - Young patients with acute leukemia share unique genetic features
Diet & Nutrition - Functional foods may offer stress management benefits
Diet & Nutrition - High-dose vitamin C supplementation heightens kidney stone risk
Diet & Nutrition - Olive oil compounds are antioxidants, anti-inflammatories, and antimicrobials
Diet & Nutrition - Vending machine program offers healthy snacks and drinks
Diffuse Anterior Scleritis - Celecoxib appears to be an effective treatment for diffuse anterior scleritis
Disease Associations - Alpha-synuclein cleavage studied, role of matrix metalloproteinases defined
Disease Associations - Leprosy bacilli examined, nature of Schwann cell proliferation clarified
Disease Associations - Quinolone signal synthesis studied, regulation in Pseudomonas defined
Disease Monitoring - European monitoring of antibiotic-resistant bacterium indicated
Docetaxel - Alternative docetaxel administration schedule evaluated
Drug Abuse - Meth users show symptoms similar to brain injury patients
Drug Delivery - "Smart" bio-nanotubes developed
Drug Delivery - Cargo molecules obstruct arginine-rich cell-penetrating peptide uptake
Drug Delivery - Dextran hydrogels confer controlled release of therapeutic growth factors
Drug Delivery - Electronic micropump nebulizers effective for ventilated neonates
Drug Delivery - Enteric-coated xyloglucan beads show promise as drug transporter
Drug Delivery - Peptide transporters improve targeted drug delivery
Drug Development - Canadian regulatory body grants approval to start cystic fibrosis trial
Drug Development - Company adds two assays to its broad kinase portfolio
Drug Development - Company files for European marketing approval of Thelin
Drug Development - Company launches cell-based assay technology for studying cell signaling events
Drug Development - Electrophoresis-based test detects enantiomeric impurity
Drug Development - Eric J. Leire joins heparin-focused company as CEO
Drug Development - First European patients enrolled in phase III study of cardiogenic shock drug
Drug Development - Grant funding boosts cancer program development
Drug Development - Interim analysis of beta-amyloid trial released
Drug Development - Isis Pharmaceuticals awarded contract for up to $1.1 million
Drug Development - Merck & Co. reaches clinical milestone using homologous recombination technology
Drug Development - Milestone achieved in collaboration with Merck & Co.
Drug Development - NDA submitted to U.S. FDA for Neurodex for pseudobulbar affect indication
Drug Development - Phase I clinical trial initiated for treatment of mild cognitive impairment
Drug Development - Phase I trial of C. difficile vaccine commences
Drug Development - Phase III trials to start for targeted lung cancer treatment
Drug Development - Preclinical data on human papillomavirus, Lassa fever therapy reported
Drug Development - U.K. patient enrollment commences in multiple sclerosis trial
Drug Development - Warning label expanded for Kadian
Drug Discovery - Antibacterial and antiviral peptide isolated from soya beans described
Drug Metabolism - Novel LC-MS/MS assay measures microsomal glucuronide transport
Drug Resistance - Cytomegalovirus drug resistance mutations phenotyped
Drug Safety - Drug safety coalition warns of counterfeit drugs in European supply chain
Drug Safety - InkSure signs contract for protection of ethical pharmaceuticals
Dyslipidemia - Effects of acute coffee ingestion on lipid levels determined
Embryonic Stem Cell Research - Patient-specific ESCs derived from somatic cell nuclear transfer blastocysts
End-Stage Renal Disease - Cortical excitability characterized in different patient populations
Endocrinology - Decoy therapy raises estrogen receptor alpha protein in breast cancer cells
Endocrinology - Glycodelin analyzed, cholesterol efflux and spermatozoa effects revealed
Endocrinology - Growth hormone status affects vascular growth modulators
Endocrinology - New findings in the area of endocrinology described
Endotoxic Shock - PPARgamma ligand 15d-PGJ2 ameliorates murine endotoxemia
Entamoeba Histolytica - Entamoeba histolytica Gal/GalNAc lectin-associated proteins analyzed
Enterococcal Infection - Antimicrobial resistance of enterococci in Turkey characterized
Enterocolitis - Necrotizing enterocolitis associated with Clostridium perfringens
Enzymology - Ascochlorin inhibits renal carcinoma cell invasion
Enzymology - Endostatin fragments cut off proangiogenic functions
Enzymology - Recent findings in enzymology provide new insights
Enzymology - Tyrosine kinase inhibitors modify the invasive phenotype of prostate cancer
Epidemiology - Combined genetic polymorphisms encourage chronic hepatitis C progression
Episcleritis - Artificial tears superior to topical ketorolac for treatment
Epstein-Barr Virus - SM protein enhances expression of Epstein-Barr virus lytic genes
Escherichia Coli - E. coli 0157:H7 outbreak caused by nonintact blade-tenderized frozen steaks
Estrogen - Estrogen elicits cortical zone-specific effects on fetal adrenal gland growth
Familial Hypercholesterolemia - DNA array provides information about mutations and familial hypercholesterolemia
Fibrin Glue - Intralesional injection of Tisseel fibrin glue used for lymphangioma resection
Finance - Amex to trade options on pharmaceutical firm
Finance - Biopharma company reports first quarter 2006 financial results
Finance - Biopharmaceutical company announces second quarter 2005 results
Finance - Biopharmaceutical company reports Q2 29% revenue growth over prior year
Finance - Biotech company announces approval of NASDAQ SmallCap Market transfer
Finance - Biotech company reports 20% increase in earnings
Finance - Biotechnology research corporation reports Q2 financial results
Finance - Cancer vaccine developer approved by NASD for trading on Bulletin Board
Finance - Clinical research organization announces second quarter results
Finance - Company reports Q2 results, announces trials for ispinesib
Finance - Cosmetic treatment company reports revenues for second quarter 2005
Finance - Diabetes-focused therapeutics developer reports second quarter financial results
Finance - Drug delivery company reports loss of $0.12 per share
Finance - Drug development services provider announces financial results
Finance - Drug-delivery company plans to reduce convertible debt balance by $5 million
Finance - Electronic clinical data capture company announces financial results
Finance - European biotech company raises financing with institutional investors
Finance - Food products company reports increase in yearly revenues
Finance - Genomics-focused pharma reports Q2 loss of $15.7 million
Finance - HCA reports Q2 results of $0.90 per diluted share
Finance - Health behavioral change company raises $2 million of growth capital
Finance - Health benefits company reports results for second quarter 2005
Finance - Health products company reports second quarter results
Finance - Human tissue products company reports record second quarter 2005 results
Finance - Infections-focused biotechnology company reports second quarter 2005 results
Finance - Medical device firm reports record quarterly revenue of $38.7M
Finance - Men's health company reports Q2 net loss of $10 million
Finance - Micropump maker reports Q2 total revenues of $6.1 million
Finance - Molecular medicines company reports second quarter 2005 financial results
Finance - Nanotechnology company included in new Russell Microcap Index
Finance - Neuroscience company reports loss of $0.13 per share
Finance - Oncology drug maker records loss of $0.47 per share
Finance - Oncology-focused biosciences corporation reports Q2, 6-months 2005 results
Finance - PBM reports record second-quarter net income of $102 million
Finance - Panzem maker reports Q2 net loss of $4.3 million
Finance - Pharma company reports second quarter 2005 results
Finance - Pharma firm repurchases part of Eurobond issue, launches new hybrid bonds
Finance - Pharmaceutical company raises $20M in common stock private placement
Finance - Pharmaceutical company raises $30M in series C financing
Finance - Pharmaceutical company reports 320% revenue increase for second quarter 2005
Finance - Pharmaceutical company reports loss of $0.12 per share
Finance - Pharmaceutical company reports profits ahead of plan, revises year forecast up
Finance - Pharmaceutical company reports record sales for second quarter, first half 2005
Finance - Pharmaceutical company reports second quarter 2005 financial results
Finance - Pharmaceutical firm adopts amended, restated stockholder rights agreement
Finance - Pharmaceutical firm announces underwriter exercises option
Finance - Pharmaceutical firm reports $0.10 per share dividend
Finance - Pharmaceutical firm reports 12.1% increase in revenue
Finance - Pharmaceutical firm reports loss of $0.94 per share
Finance - Pharmaceutical firm reports record sales of $124.5M
Finance - Pharmaceutical firm sets price for public offering
Finance - Pharmaceuticals group reports good second quarter results with milestones met
Finance - Tysabri developer reports second-quarter 2005 financial results
Finance - VNS maker announces revised long-term sales outlook and guidance for fiscal 2006
Finance - Viread maker reports Q2 revenues of $495.3 million, up 55%
Finance - Washington genetics-focused company reports Q2 2005 financial results
Fitness & Wellness - Age does not impair key adaptations to exercise tolerance
Fitness & Wellness - U.S. surgeon general issues first call to action to improve health of disabled
Fucoidan - Fucoidan inhibited adhesion of adenocarcinoma cells to fibronectin
Galectin-1 - Galectin-1 induced apoptosis in human breast cancer and trophoblast tumor cells
Gastric Cancer - Paclitaxel and carboplatin combined to treat advanced gastric cancer
Gastroenterology - Recent findings illuminate research in gastroenterology
Gastroenterology - Reduced-dose rabeprazole has high acid-suppressive efficacy
Gastroenterology - VEGF expression and angiogenesis fluctuate shortly after ulcer formation
Gastrointestinal Stromal Tumors - New developments in gastrointestinal stromal tumors reviewed
Gene Expression - Changes in bacterial gene expression over the course of infection examined
Gene Mutations - Antibiotic resistance in Chlamydia spp. linked to gene mutations
Gene Regulation - Osmotic elements mediate paternally expressed gene 3 expression
Gene Research - A small interfering RNA expression vector library defines apoptosis pathways
Gene Silencing - Positional modifications affect short interfering RNA activity
Gene Silencing - RNA interference elicits tumor response despite hypoxia-induced VEGF-A
Gene Therapy - Enhanced CD20 expression in tumor B cells controlled by ERK-dependent mechanisms
Gene Transfer - SART-1 gene transduction causes cellular destruction
Generic Drugs - Approval granted to market Glimepiride; Vogseal launched in Japan
Generic Drugs - Private labels making steady inroads into U.S. nonprescription drug market
Generic Drugs - U.S. FDA grants tentative approval of tramadol and acetaminophen tablets
Genetics & Genomics - Filtering methods for time course microarray data compared
Genetics & Genomics - Technology company to collaborate with hospital in gene analysis
Genital Herpesvirus Infection - Topical microbicides needed for prevention of genital herpes infections
Genomics - Genomics company to provide physicians on patient's genetic profile
Glycemic Control - Three multiple injection regimens for type 1 diabetes compared
Gout - End-of-phase 2 U.S. FDA review on gout therapy complete, phase 3 trial to begin
Grants - Company awarded SBIR grant for cardiac modeling
Grants - Scientists Invited to apply for new Alzheimer drug discovery grant program
HAM/TSP Pathogenesis - Interferon-beta 1a affects immune mechanisms central to HAM/TSP pathogenesis
HIV/AIDS - Pharma firm reaches agreement with Brazilian government for AIDS drug
HIV/AIDS Coinfection - Neisseria gonorrhoeae enhances infection of dendritic cells by HIV-1
HIV/AIDS Disease Progression Risk Factors - Pattern/type of non-injection drug use associated with progression to AIDS
HIV/AIDS Drug Development - Amino acid Asn136 of HIV-1 RT enables rational design of RT inhibitors
HIV/AIDS Drug Development - Mesuol inhibits HIV-1 replication by targeting NF-kappa B pathway
HIV/AIDS Drug Development - Short hairpin RNAs targeting human cyclin T1 suppresses HIV-1 replication
HIV/AIDS Education - Low health literacy associated with HIV test acceptance
HIV/AIDS Education - Peer education or lecture increases HIV/AIDS knowledge among college students
HIV/AIDS Epidemiology - Differential susceptibility important determinant of steady-state HIV prevalence
HIV/AIDS Epidemiology - Majority of HIV-1 cases among Africa-born patients in Minnesota are non-B
HIV/AIDS Needlestick Injury - Postexposure practice inadequate in medical students with needlestick injury
HIV/AIDS Opportunistic Infection - Calciviruses may be important opportunistic pathogen in HIV-infected children
HIV/AIDS Pathogenesis - CD4+ cells have impaired base excision repair/oxidative base lesion accumulation
HIV/AIDS Pathogenesis - Cultured myeloid dendritic cells from HIV patients fail to differentiate
HIV/AIDS Pathogenesis - HIV Tat induction of IL-10 dysregulation associated with PKR activation
HIV/AIDS Pathogenesis - Infectivity of CXCR4-using isolates depends on CD4 expression
HIV/AIDS Pathogenesis - Peripheral S-phase T cells in HIV disease have a central memory phenotype
HIV/AIDS Pathogenesis - Reports describe recent advances in HIV/AIDS pathogenesis research
HIV/AIDS Perinatal Transmission - Nevirapine resistance after single NVP dose higher in women with HIV-1 subtype C
HIV/AIDS Pharmacokinetics - Body weight/female gender affects enfuvirtide clearance but not safety/efficacy
HIV/AIDS Prevention - HIV prevention program increases willingness to reduce adolescent risk behaviors
HIV/AIDS Prognostic Marker - Early HIV-1 PBMC DNA level predicts disease progression independent of RNA/CD4+
HIV/AIDS Research - CHMP offers positive opinion in Europe for Tipranavir
HIV/AIDS Research - Enrollment complete in phase 1 trial of PRO 140
HIV/AIDS Research - Phase 1/2a study results indicate maraviroc is well tolerated
HIV/AIDS Research - Phase IIb sudy shows Reverset trial results reported
HIV/AIDS Research - Single-chain antibody against HIV-1 external glycoprotein gp120 developed
HIV/AIDS Research - Soluble HIV trimeric Env fragment adopting prefusion gp41 structure developed
HIV/AIDS Risk Behavior - Adults with severe mental illness engage in risky sexual behaviors
HIV/AIDS Risk Behavior - Sexual risk behavior is high among youths in psychiatric care
HIV/AIDS Susceptibility - Screening test may be developed to determine susceptibility to HIV/AIDS
HIV/AIDS Therapy - Company begins phase III trials with aplaviroc (873140) for HIV treatment
HIV/AIDS Therapy - Company provides update of HIV/AIDS drug candidate
HIV/AIDS Therapy - Findings describe new data in HIV/AIDS therapy research
HIV/AIDS Therapy - HIV therapy success rates similar in developing and developed world
HIV/AIDS Therapy - Highly active antiretrovirals for HIV can substantially reduce AIDS rates
HIV/AIDS Therapy - Long-term safety data of antiretroviral in HIV patients with hepatitis reported
HIV/AIDS Therapy - Pharmacokinetics study results presented on once-daily HIV combination therapy
HIV/AIDS Therapy - Phorbol derivative shows promise as anti-HIV agent
HIV/AIDS Therapy - Study shows effectiveness of protease inhibitor in AIDS treatment
HIV/AIDS Therapy - Trial data on HIV antiviral therapy presented at international AIDS meeting
HIV/AIDS Transmission - Incorporation of ABO antigens by HIV-1 may affect viral transmission
HIV/AIDS Treatment - Data on PA-457 drug activity after oral dose in HIV-infected patients presented
HIV/AIDS Treatment - Invirase boosted with ritonavir not associated with development of resistance
HIV/AIDS Treatment - Patients more satisfied with once-daily dosing of EPZICOM
HIV/AIDS Treatment Failure - Prevalence of virologic response disappears after 96 weeks on HAART
HIV/AIDS Vaccines - Researchers provide details of new studies and findings in the area of HIV/AIDS vaccines
HIV/AIDS-Associated Eye Disease - HAART decreases morbidity related to HIV/AIDS-associated eye diseases
HIV/AIDS-Related Drug Use - Methadone treatment decreases heroin overdose-related mortality in HIV patients
HIV/AIDS-Related Kaposi Sarcoma - HAART plus liposomal doxorubicin induces tumor remission in HIV-related KS
Head & Neck Cancer - Paclitaxel, cisplatin, 5-fluorouracil and radiotherapy managed SCC
Heart Failure - Data supports advancement of cardiac myosin activator
Heart Failure - Spironolactone prescriptions increased after study publication
Heartburn - U.S. FDA accepts filing of NDA for ZEGERID Chewable Tablets
Hematology - Genetically modified natural killer cells overcome HLA-mediated resistance
Hematology - Researchers describe findings in hematology studies
Hematology - Suicide genes quell graft-versus-host disease after stem cell transplantation
Hematopoietic - ESCs grown without embryonic fibroblasts/conditioned media undergo hematopoiesis
Hemolytic Uremia - Streptococcus pneumoniae plus hemolytic uremia is rare in Canada
Henoch-Schonlein Nephritis - Azathioprine improves efficacy of steroid treatment in children
Heparin - Homer-1a studied, roles in pyramidal cell homeostatic regulation revealed
Hepatitis B Prevention - School-based factors predict the success of hepatitis B immunization programs
Hepatitis B Therapy - HIV therapy tenofovir battles hepatitis B infection
Hepatitis B Therapy - Oral tenofovir stops woodchuck hepatitis virus infection in woodchucks
Hepatitis B Therapy - Peginterferon is superior therapy for hepatitis B e antigen-positive infection
Hepatitis C Therapy - Findings advance knowledge in hepatitis c therapy research
Hepatitis C Therapy - First demonstration of systemic siRNA efficacy at therapeutic doses published
Hepatitis C Therapy - Ursodeoxycholic acid normalizes lipid peroxides in patients with hepatitis C
Hepatitis C Treatment - Development of nucleoside analog for treating hepatitis C initiated in Japan
Hepatitis C Virus - Antivirals defeat hepatitis C in cirrhotic patients after liver transplants
Hepatitis C Virus - CD8+ T cell response to hepatitis C infection wanes over time
Hepatitis C Virus - Company initiates phase Ib study of GI-5005 for chronic hepatitis C infection
Hepatocellular Cancer - Sirolimus improves the survival of patients transplanted for liver cancer
Hepatocellular Carcinoma - Interferon prevents liver cancer in chronic hepatitis C non-responders
Hepatocellular Carcinoma - Risk factors associated with bile leakage after hepatic resection
Hepatoma - Transforming growth factor beta mediated apoptosis in human hepatoma cells
Herpesvirus - Cathelicidin analyzed, expression and antimicrobial activity defined
Herpesvirus - Varicella-zoster virus prevalence in day-care workers in Lyon reported
Hip Replacement - Aprotinin and EACA treatment reduces post-THA blood loss
Hormone Replacement Therapy - Research add new data to hormone replacement therapy body of knowledge
Hyperlipidemia - Clinicians must be aggressive about hyperlipidemia in transplant patients
Hypertension - ACE I/D polymorphism is not useful to predict anti-HT treatment response
Hypoglycemia - CYP2C9 slow metabolizer genotypes increase severe hypoglycemia risk
Imaging - Electronics company and RaySearch Laboratories expand strategic relationship
Imidazole - Iodinated nitroimidazoles used as radiosensitizers
Immunity - Chemerin examined, neutrophil-mediated maturation demonstrated
Immunogenetics - Immunoglobulin KV genes isolated by PCR from macaque genomic DNA
Immunotherapy - GCAN 101 trial underway
Infection - Gonococci studied, effect on carcinoembryonic antigen-expressing B cells shown
Infection Control - Data: Pathogen inactivation process improves ACL reconstructive surgery results
Infectious Diseases - Galectin-1 examined, effect on Nipah virus and dendritic cells defined
Infectious Diseases - Risk to community of exposure to bacteria from previously hospitalized patients
Inflammatory Bowel Disease - Cannabis-based drugs could offer new hope for IBD patients
Information Technology - Beta-blocker therapy trial included in journal used information from database
Information Technology - OPTIMIZE-HF registry selected for heart failure program
Insomnia - FDA approves ROZEREM (ramelteon), sleep medication
Insomnia - New drug application accepted for insomnia treatment
Insomnia - U.S. FDA grants approval for ramelteon therapeutic for treatment of insomnia
Insulin Resistance - High fat diets modulate genes required for mitochondrial function
Insulin Resistance - PPAR-gamma-activating angiotensin receptor blockers induce adiponectin
Ischemia - Glomerular epithelial cell injury studied, role of ER protein shown
Ischemia - Reports add new data to ischemia research
Kidney Cancer - Gene therapy designed to seek VHL mutations may benefit renal cancer patients
Kidney Disease - Company reports positive results from DCOR trial favoring use of Renagel
Knee Replacement - Epidural analgesia improves early post-TKA rehabilitation
Knee Replacement - Epinephrine-augmented hypotensive epidural anesthesia lowers blood loss
Leukemia - Amino acid concentrations in cerebrospinal fluid measured in ALL children
Leukemia - Children do not show increased susceptibility for developing secondary AML
Leukemia - Glycated fibrinogen-methotrexate conjugates showed antileukemic activity
Leukemia - Intrathecal chemotherapy evaluated in children with acute leukemia
Liver Cancer - Dynamin 2 interactions let radiation send adenoviruses into liver cells
Liver Cancer - Microwave tissue coagulation yields acceptable results in resected livers
Liver Cancer - New findings in liver cancer described
Liver Cancer - Researchers discover link between viral infection and liver cancer
Liver Transplantation - Artificial neural network and genotyping predict liver cancer recurrence
Lung Cancer - Acute esophageal toxicity detected in NSCLC cancer patients after radiotherapy
Lung Cancer - Current approaches in chemotherapy of advanced and metastatic NSCLC detailed
Lung Cancer - Lung cancer incidence increasing in Sardinia
Lung Transplant - BLT1-mediated T-cell trafficking plays key role in rejection
Lymphoma - MTAP gene silenced by promoter hypermethylation in lymphoma cells
MALT Lymphoma - Clinical features of Helicobacter heilmannii infection studied
Malaria - P. falciparum malaria occurred in visitors to E. Coast of Dominican Republic
Malaria - Plasmodium falciparum STEVOR peptides studied, RBC binding defined
Malaria - Parasite-specific IgM plays role in immune response to malaria
Malaria - Research in malaria provides new insights
Malaria Vaccine - A. nancymaae is an animal model for malaria subunit vaccine development
Market Analysis - Biological and silver dressings lead growth in $1.5B burn market
Market Analysis - Pharma companies rate life cycle management functions as adequate
Marketing - Genomics company launches new corporate marketing and product branding campaign
Marketing - Market report indicates makers of lung cancer drugs spend $38 million on launch
Measles Vaccines - Researchers describe findings in measles vaccines studies
Medical Devices - Immunicon announces quality system certification
Medical Imaging - Novel system enables automated micro PET-CT-SPECT image fusion
Medicare - Grocery chain, CMS launch program to help give seniors access to drug benefits
Melasma - FRAXEL laser technology for melasama treatment cleared by U.S. FDA
Meningitis Vaccine - Antibiotic exposure impedes pneumococcal meningitis vaccine protection
Mental Health - Dr. Ed Knight receives psychiatric rehab association Chairperson's Award
Mergers & Acquisitions - Agreement signed to purchase Kirk Pharmaceuticals
Mergers & Acquisitions - Healthcare Technologies signs agreement for the acquisition of Immvarx, Inc.
Mergers & Acquisitions - Invitrogen signs definitive agreement to acquire BioSource International
Mergers & Acquisitions - Pharmaceutical provider for the elderly expands by acquisition
Mergers & Acquisitions - Protein therapeutics firm acquires LemnaGene S.A.
Mergers & Acquisitions - Specialty pharmacy and distribution company to be acquired by Express Scripts
Microbiology - Lactobacillus acidophilus by-products stimulate embryo cell proliferation
Mucin - Gastric mucin secretion analyzed, growth factor receptor mediation clarified
Multidrug Resistant - Carbapenem use {{>=}}7 days risks multidrug resistant to P. aeruginosa
Multiple Myeloma - COX-2 is an independent predictor of poor outcome in multiple myeloma
Muscular Dystrophy - Muscle side population cells reveal myogenic potential
Muscular Dystrophy - Safety and efficacy of creatine and glutamine evaluated
Mycobacterium Avium - High-temperature/short-time pasteurization inactivates M. avium in milk
Mycobacterium Kansasii - High phenotypic variability of M. kansassi may complicate identification
Mycobacterium Tuberculosis - Early treatment improves MTB-induced disseminated intravascular coagulation
Mycobacterium Tuberculosis - Inducible promoter generates conditional Mycobacerium tuberculosis auxotroph
Mycobacterium Tuberculosis - Pyrosequencing assay rapidly detects rifampin-resistant M. tuberculosis
Mycobacterium Tuberculosis - Virulence of MTB isolates dependent on phenolic glycolipid produced by bacilli
Mycoplasma Bovis - Mycoplasma bovis analyzed, new adhesin in low-passaged strain identified
Mycosis Fungoides - Therapeutic approach to mycosis fungoides and Sezary syndrome addressed
Myocardial Infarction - Early EPS/ICD treatment doesn't improve outcome for high-risk patients
Myocardial Infarction - Research links poor aspirin response to increased risk of heart attack or stroke
Myocardial Infarction - Seeded scaffolds intervene to aid the infarcted heart
Myocardial Infarction - Treatment with captopril and valsartan produced similar cardiac changes
Natriuretic Peptides - Natriuretic peptides analyzed, effect on gallbladder muscle defined
Neurology - New findings in neurology described
Neurology - Prostaglandin effect analyzed, role of EP2 and EP4 receptors defined
Neurology - Serotonin receptor expression analyzed, hippocampal ontogeny clarified
Neuropathic Pain - Lacosamide data positive in Phase III trial
Neuropathy - ND6 gene mutations cause Leber hereditary optic neuropathy
Neuroscience - A single molecule - Nova - helps control proteins that control synapses
Neuroscience - Calpain inhibitors may play a therapeutic role in NMDA-related disease
Neuroscience - Cochlear Ca2+ signaling analyzed, role of nitric oxide clarified
Neuroscience - Modified embryonic stem cells produce tumors after spinal cord implantation
Neuroscience - Mouse retinal nuclear elements favor endogenous gene repair activity
Neuroscience - New findings in the area of neuroscience described
Neurosteroids - Neurosteroid receptor studied, sensitivity to endocrine disruption reported
Neurotoxins - Neonatal MSG treatment has deleterious effects on rat behavior
Neurotransmitters - Blood-retinal barrier studied, nature of Leu transport defined
Non-Hodgkin Lymphoma - Data safety monitoring board recommends continuation of MyVax phase III trial
Non-Hodgkin Lymphoma - Risk of non-Hodgkin lymphoma associated with occupational exposure
Norovirus - Multiplex real time RT-PCR assay quantitates norovirus genogroups I and II
Nosocomial Infections - Healthcare system starts MRSA screening program
Obesity Surgery - Inpatient pain medication after laparoscopic gastric bypass examined
Obesity Therapy - New medically supervised weight-loss program introduced
Obesity Therapy - Reports add new data to obesity therapy research
Obstetrics - Study reveals effective way for women to breathe easier during labor
Obstructive Sleep Apnea - Alternative therapy proposed for mild sleep-disordered breathing in children
Oncogenesis - New findings in oncogenesis described
Oncology - Heparanase helps establish cancer metastasis to the bone
Oncology - Low VEGF levels may indicate lung cancer's response to gefitinib
Oncology - Mathematical model predicts effect of acidity on tumor growth
Oncology - Microvascular density predicts the survival of bladder cancer patients
Oncology - Oblimersen enhances the antitumor effects of gimatecan in melanoma xenografts
Oncology - Recent findings illuminate research in oncology
Oncology - Securin is a biomarker for breast cancer invasion
Ophthalmic Contact Dermatitis - Sodium lauryl sulfate improves patch test sensitivity
Ophthalmology - Choroidal neovascularization resolves after laser beam injury to the eye
Ophthalmology - Endostatin might inactivate choroidal neovascularization-dependent disorders
Ophthalmology - High-grade myopia is linked to regions of chromosome 2
Ophthalmology - Plasmid DNA encoding interleukin-18 attacks herpetic stromal keratitis
Opiates - Novel chromatography system efficiently separates opiate alkaloids
Oral Health - Salivary pleomorphic adenomas produce a number of VEGF splicing forms
Orthopedics - A new SOST gene mutation associates with skeletal hyperostosis in siblings
Osteomyelitis - Novel goat model facilitates research
Osteoporosis - Bone mineral density test helps determine osteoporosis treatment strategy
Osteoporosis - New findings in the area of osteoporosis detailed
Ovarian Cancer - Chemotherapy affected mutation frequency of ovarian cancer cells
Pain Management - Colorectal distension-induced visceral pain studied, role of sauvagine defined
Pain Management - Role of NMDA receptors in neuropathic pain clarified
Pain Medicine - Novel approach prevents baclofen pump catheter migration
Pamidronate - Pamidronate and 1,24(S)-dihydroxyvitamin D-2 inhibited growth of cancer cells
Pancreatic Cancer - New treatment modalities for pancreatic adenocarcinoma needed
Pancreatic Ductal Carcinoma - Factors predicting recurrence after pancreatic ductal carcinoma resection listed
Panduratin A - Panduratin A induced apoptosis in human colon cancer HT-29 cells
Parkinson Disease - Amphetamine-related drugs effective in treating a mouse model of Parkinson
Patents - Biopharmaceutical firm awarded U.S. patent for AVR118
Patents - Company files U.S. patent application for family of DNA antimicrobial agents
Patents - Company receives notice of allowance for key U.S. EVLT patent
Patient Education - Many discharged patients do not know diagnoses, medications, side effects
Patient Follow-Up - Telephone follow-up experiences at Rapid Response Radiotherapy Program shared
Pediatric Asthma Therapy - Inhaled corticosteroids don't stunt growth in prepubertal patients
Pediatric Cardiac Surgery - Surgery for aortic coarctation has excellent results in children under 1 yr. old
Pediatric Epilepsy Therapy - Vitamin D supplement doesn't prevent treatment-induced osteopenia
Percutaneous Coronary Intervention - PCI with drug-eluting stents highly cost-effective in Germany
Personnel - Alan M. Solinger, MD, named clinical immunology VP by biopharmaceutical company
Personnel - Arun Chockalingam, PhD, named secretary general of World Hypertension League
Personnel - Benefit management company's executive elected to professional association
Personnel - Cancer therapeutics developer names Rotherham, Myers to executive positions
Personnel - Clinical trial company appoints new CFO: John Hallinan
Personnel - Company focusing on osteoporosis adds member to board
Personnel - Contract research organization appoints global clinical trial management
Personnel - Daniel L. Hartman, MD, named senior VP, product development by genetics company
Personnel - David Gury appointed to board of directors at cardiology firm
Personnel - Dean Blechman, Twinlab founding family member, named to nutrition company board
Personnel - Genomics-based drug-discovery company names Ian D. Malcolm VP
Personnel - Icoria adds Anna Mae Diehl, MD, to its scientific advisory board
Personnel - Information technology company adds member to advisory board
Personnel - IntraPace announces Chuck Brynelsen as new CEO
Personnel - John F. Cogan joins Gilead Sciences board of directors
Personnel - John O'Mullane named group VP, R&D, consumer health care, by healthcare company
Personnel - Leo Albert named VP of finance by acute care hospitals, medical centers company
Personnel - Pharma company adds member to scientific advisory board
Personnel - Pharmaceutical developer names Dan McKay VP, intellectual property
Personnel - Physical therapy management services company elects member to board of directors
Personnel - Santa Jeremy Ono, PhD, named chief scientific officer by therapeutics developer
Personnel - Thomas A. Davis, MD named chief medical officer; to lead clinical development
Personnel - Vaccine organization appoints M. M. Sharma to board of directors
Pertussis - G protein signaling analyzed, nature of functional selectivity defined
Pharmaceutical Research - Improved RNA amplification garners more cells for cancer vaccines
Pharmaceutical Research - Report focuses on outsourcing trends released
Pharmaceutical Research - Research examines pharma competitive intelligence strategies
Pharmaceutical Research - Research examines role of medical affairs in pharma companies
Pharmacology - Effects of bisphosphonates on ion channels characterized
Philanthropy - Companies partner to send medical supplies to needy hospitals in Latin America
Photomedicine - Hypericin enacts a multifocal attack on angiogenesis when kept in the dark
Physiology - Candida albicans examined, histatin-induced effects described
Pituitary Gland - Pituitary secretory granule proteins examined, retrieval and reuse clarified
Pneumococcal Vaccines - Data advance knowledge in pneumococcal vaccines research
Pneumonia - C. pneumoniae kills cells by a caspase-independent pathway
Pneumonia - Pneumococcal pneumonia examined, nature of innate immune defense clarified
Product Licensing - California university expands licenses of data mining systems biology software
Product Licensing - Florida medical school signs license agreement for coenzyme with holding company
Product Licensing - Genentech has licensed rights to use ImmunoGen's TAP technology
Product Licensing - Hythiam adds HANDS licensee in San Francisco Bay area
Product Licensing - Pharma company enters license agreement with Lavipharm Laboratories
Product Licensing - Roche Diagnostics grants rights to commercialize NT-proBNP
Progenitor Cells - Epithelial lung cell differentiation studied, protein interactions revealed
Prostate Cancer - AMACR expression altered in prostatic adenocarcinoma following hormone therapy
Prostate Cancer - Adenocarcinoma of the prostate discussed
Prostate Cancer - Concept of hormone therapy in metastatic prostate cancer reappraised
Prostate Cancer - External beam radiotherapy used as curative treatment of prostate cancer
Prostate Cancer - Findings describe new data in prostate cancer research
Prostate Cancer - Trial of ozarelix in patients with hormone-dependent prostate cancer initiated
Protease Inhibitors - Cytotoxic T lymphocytes analyzed, regulatory aspects clarified
Protein Expression - Vascular smooth muscle cells studied, p27 expression clarified
Proteomics - CD105 erases the effects of transforming growth factor on vessel growth
Proteomics - Hepatitis C N-linked glycans are instrumental to cell entry and protein folding
Proteomics - Pigpen protein intensifies oligonucleotide distribution
Proteomics - Protein-protein interactions in cancer detailed
Proteomics - Research in proteomics provides new insights
Proteomics - Researchers determine protein structure of electrical signals in the brain
Proteomics - Six new phosphorylation-site profiling services announced
Pseudomyxoma Peritonei - New surgical strategy examined for treatment of pseudomyxoma peritonei
Radiation Therapy - DNA repair genes make lung cancer cells resist radiotherapy
Radiation Therapy - Data: Electronic brachytherapy accurately delivers nonradioactive radiation
Radiation Therapy - Risk of CV mortality after irradiation for childhood cancer is increased
Receptors - Adenosine receptor studied, functional importance of surfactant revealed
Receptors - Galanin receptor analyzed, important pharmacophores for binding identified
Receptors - Muscarinic acetylcholine receptor studied, conformational changes clarified
Receptors - Myocyte oscillatory currents studied, sodium nitroprusside inhibition revealed
Reconstructive Surgery - Researchers describe findings in reconstructive surgery studies
Rectal Cancer - Role of CEA and CA 19-9 in adjuvant radiochemotherapy assessed
Renal Cell Cancer - Renal cell carcinoma reported secondary to tuberculous nephritis
Renal Cell Carcinoma - Platelet-derived growth factor blockade stops kidney cancer progression
Reproductive Medicine - Progesterone is a major mediator of endometrial angiogenesis
Respiratory Distress Syndrome - Nitric oxide added to CPAP treatment improves oxygenation
Respiratory Medicine - Expanded development agreement for asthma, other respiratory therapies signed
Respiratory Medicine - Inhaled corticosteroid delivery devices reviewed
Respiratory Medicine - Positive final results of in vitro antiviral efficacy studies released
Restorative Dentistry - Antibiotic-loaded membranes enhance guided tissue regeneration
Retinoblastoma - Neurokinin-1-receptor antagonist acted as antitumoral agent on retinoblastoma
Retinopathy - Adeno-associated viral vectors transport therapeutic genes into the retina
Rosacea - Phase 3 trial examinig Oracea for rosacea presented at conference
SARS - Anti-SARS-coronavirus drugs are crucial for control of future outbreaks
SARS - Novel macaque model developed
SARS - Protective mask usefulness during SARS outbreak varies among healthcare workers
SARS - Quarantine is cost saving and effective in containing emerging infections
Sexual & Reproductive Health - Newly researched infertility treatment comes to western U.S.
Sexual & Reproductive Health - Survey reveals personal sacrifices take a toll on infertile women
Smallpox Vaccine - Stable/effective smallpox vaccine constructed from highly attenuated vaccinia
Staphylococcus Aureus - Common food preservative may have antibiotic properties
Statins - Rosuvastatin may be an option for patients requiring 50% LDL reduction
Stem Cell Research - BMSCs have limited plasticity to transdifferentiate into cardiac cells in vitro
Stem Cell Research - Bone graft clinical trial expanded to include Nebraska Medical Center
Stem Cell Research - Collaboration to isolate stem cell-specific differentiation markers
Stem Cell Research - Dopamine specifically inhibits forebrain neural stem cell proliferation
Stem Cell Research - Postnatal muscle-derived stem cells have extra capacity for self-renewal
Stem Cell Research - TGF-beta 1 tightly regulates intestinal mast cell growth/phenotype/function
Stem Cell Research - TGF-beta-1-2-3 & IFN-beta induce hepatocyte growth factor secretion by microglia
Stem Cell Transplantation - CD133+ SCs used for haploidentically mismatched peripheral blood SCT
Stem Cell Transplantation - Fibrinolytic test findings may facilitate early VOD diagnosis in pediatric HSCT
Stem Cell Transplantation - HLH patients with NK-cell deficiency type 3 will probably require SCT to survive
Stem Cell Transplantation - High-dose cyclophosphamide effective for refractory MM after SCT relapse
Stem Cell Transplantation - Most HLH patients using matched related or unrelated donor survive SCT
Stem Cell Transplantation - New research in the area of stem cell transplantation detailed
Stem Cell Transplantation - Nonmyeloablative SCT corrects disease phenotype in leukocyte adhesion deficiency
Stem Cell Transplantation - Reduced-intensity SCT successful in malignant lymphoma/ileostomy patient
Stroke - Angiopoietin-2 supports VEGF-induced brain angiogenesis
Stroke - Atherosclerosis and cervical artery dissection are not well examined
Stroke - Expansion of SAINT II phase III trial with CEROVIVE announced
Stroke - Study examined predictors of reocclusion in stroke patients treated with tPA
Stroke - Transthoracic ECG should be performed for all stroke patients in sinus rhythm
Systemic Lupus Erythematosus - First patient treated in pivotal phase III lupus nephritis study
TIssue Injury - Tissue and nerve injury studied, analgesic effects clarified
Tetanus - ADACEL vaccine begins shipping in the U.S.
Tissue Engineering - Autologous blood vessels engineered from human cells
Tissue Engineering - BMP-2 induces chondrocyte-specific gene expression in synovium-derived SCs
Tissue Engineering - Cultured porcine cartilage pellets used to study rheumatoid arthritis
Tissue Engineering - Keratocan examined, regulation by lumican revealed
Tissue Engineering - Tissue engineering for airway reconstruction avoids tracheotomy
Tissue Engineering - Tissue-engineered vascular autografts seeded with autologous bone marrow cells
Toxoplasma Gondii - Stage-specificity of SRS Ags determines immunogenicity in T. gondi infection
Transplant Medicine - Contrast agent allows better MRI screening of living liver donors
Transplant Medicine - Recent findings illuminate research in transplant medicine
Tuberculosis - Beijing genotype is a major cause of drug-resistant tuberculosis in Kazakhstan
Tuberculosis - Differential regulation of local immune response crucial for containment of MTB
Tuberculosis - ELISA more sensitive than immunoblotting for detection of tuberculosis antibody
Tuberculosis - High prevalence of tuberculosis among health care workers in Kampala
Tuberculosis - Low sunlight/vegetarian diet cause of vitamin D deficiency in foreigners with TB
Tuberculosis - Pharma company joins consortium to develop tuberculosis drugs
Tuberculosis - Short-course chemotherapy safe/effective in pediatric respiratory tuberculosis
Tuberculosis - Targeted screening strategies for pulmonary tuberculosis in prisons unreliable
Tuberculosis - Tuberculosis drugs not handled properly in lower southern Thailand
Tuberculosis - Tuberculosis risk patterns determined for recent immigrants to Ontario
Tuberculous Meningitis - Isoniazid + rifampicin resistance strongly predictive of death in TB meningitis
Tularemia Vaccines - Studies describe new findings in tularemia vaccines research
Tumor Suppression - Interleukin-12 immunotherapy hastens the demise of solid tumors
Type 1 Diabetes - Pancreatic islet transplantation stabilizes diabetes-related pathologies
Umbilical Cord Blood - Mannose-binding lectin and surfactant protein D lower in preterm neonates
Urology - Preoperative chlormadinone reduces blood loss during prostate surgery
Vaccine Development - Development progress of particulate vaccines for biowarfare reviewed
Virology - Data advance knowledge in virology research
Virology - GB virus C protects patients coinfected with HIV
Virology - NESI protein is essential for the assembly of hepatitis delta virus
Virology - Positive results reported on five projects using Neugene antisense drugs
Visceral Leishmaniasis - Novel triphenyl tin complex active against Leishmania donovani
Vitamin B6 - Pyridoxal 5'-phosphate measurements in serum compared
West Nile Fever - WNF encephalitis may present with functional/intellectual impairment in elderly
Yersinia - MAPK/NF-kappa B inhibition needed for rapid apoptosis in infected cells
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