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Cancer Vaccines



Researchers publish new studies and findings in the area of cancer vaccines



August 26th, 2005

New findings from the United States and Japan describe advances in cancer vaccines.

Study 1: Interleukin 4 tumor cell vaccine needs type-1 immunity for sustained efficacy.

"We previously demonstrated that interleukin (IL)-4 gene-transfected glioma cell vaccines induce effective therapeutic immunity in preclinical glioma models, and have initiated phase I trials of these vaccines in patients with malignant gliomas. To gain additional mechanistic insight into the efficacy of this approach, we have treated mice bearing the MCA205 (H-2(b)) or CMS-4 (H-2(d)) sarcomas," investigators in the United States report.

"IL-12/23 p40-/- and...


Source: Drug Week (2005-08-26)

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