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Gastroenterology



Recent studies add new data to gastroenterology research



August 26th, 2005

Investigators in Mexico, Japan and Germany have published new gastroenterology data.

Study 1: Researchers provided a clinical and biological overview of gastrointestinal stromal tumors (GIST).

According to recent research from Mexico, "In the last few years a body of knowledge has been generated on the molecular basis of GIST. These mesenchymal tumors are characterized by the expression of KIT protein and because they have an activating mutation in a class III receptor tyrosine kinase gene (KIT or PDGFRA)."

"Several KIT-activating mutations, which are largely responsible for the development of this tumor, promote cell survival,...


Source: Drug Week (2005-08-26)

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