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Anal Pain
Nicorandil implicated in idiopathic anal ulceration
August 26th, 2005
Nicorandil was implicated in idiopathic anal ulceration. "Several reports have implicated nicorandil as a reversible cause of anal ulceration. We have recently commenced a specialist clinic for patients presenting with severe anal ulceration to assess treatment in this difficult group," scientists in England reported. "Recognition of this association may avoid unnecessary surgery. Twenty-six patients treated with nicorandil had severe painful anal ulceration. Examination under anesthesia was required to biopsy the lesions to exclude neoplasia or inflammatory bowel disease," explained M. Katory and colleagues, Sheffield Teaching Hospitals NHS...
Source: Drug Week (2005-08-26)
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