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Anesthesia
Study shows effect of multiple opoids on open-heart surgery patients
August 26th, 2005
In the first reported study on patients using buprenorphine for at least 2 weeks before open-heart surgery with fentanyl-based anesthesia, no overlap of effects occurred between the two opioids, as reported in the Journal of Opioid Management. Patients wearing a buprenorphine patch (Transtec, Napp Pharmaceuticals, Cambridge, UK) for at least 2 months for treatment of chronic pain were compared to patients with no previous opioid use during open-heart surgery. The study was undertaken to see if buprenorphine has the same effect on fentanyl-based anesthesia as morphine, which is known to reduce fentanyl's effectiveness. Patients using...
Source: Drug Week (2005-08-26)
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