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Angiology
Laser perforation mobilizes matrix graft adaptation in treated arteries
August 26th, 2005
Laser perforation mobilizes matrix graft adaptation in treated arteries. "Autologous cells migrate only slightly into acellular matrix grafts. This study was carried out in small-diameter, allogeneic matrix grafts to investigate the effects on cell repopulation and remodeling caused by increased wall porosity induced by laser perforation," researchers in Austria report. "Allogeneic ovine carotid arteries were decellularized by dye-mediated photooxidation (Photofix). Matrix grafts (10 cm X 4 mm i.d.) were perforated with holes of 50 mcm diameter at a density of 50 holes/cm2 using a Ti-sapphire laser. The grafts were implanted in the carotid...
Source: Drug Week (2005-08-26)
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