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Antibacterial Agents



Phage therapy examined as treatment option for diarrheal disease



August 26th, 2005

Phage therapy was examined as a treatment option for diarrheal disease.

"Fifteen healthy adult volunteers received in their drinking water a lower Escherichia coli phage T4 dose (103 PFU/ml), a higher phage dose (105 PFU/ml), and placebo," explained researchers in Switzerland. "Fecal coliphage was detected in a dose-dependent way in volunteers orally exposed to phage."

"All volunteers receiving the higher phage dose showed fecal phage 1 day after exposure; this prevalence was only 50% in subjects receiving the lower phage dose," observed A. Bruttin and colleagues, writing in the journal Antimicrobial Agents and...


Source: Drug Week (2005-08-26)

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