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Neuroscience
Research in neuroscience provides new insights
August 26th, 2005
Reports from Japan and the United States highlight recent research on neuroscience. Study 1: According to recent research from Japan, pregnenolone sulphate (PS) attenuates AMPA cytotoxicity on rat cortical neurons. "Neuroactive steroids can modulate brain excitability by interaction with several neurotransmitter receptor-associated channels. These compounds may thus exert profound influences on excitotoxic injury, i.e. neuronal cell death triggered by over-activation of glutamate receptors. "It has been reported that PS and pregnenolone hemisuccinate (PHS) augment N-methyl-D-aspartate (NMDA) neurotoxicity in rat cultured neurons....
Source: Drug Week (2005-08-26)
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