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Oncology
Researchers describe findings in oncology studies
August 26th, 2005
Oncology research advances have been reported from Taiwan, Italy and Belgium. Study 1: Transcription factor Spz1 sends tumor cell proliferation into overdrive. According to recent research from Taiwan, "bHLH-zip proteins usually play important regulatory roles in cell growth and differentiation. In this study, we show that Spz1, a bHLH-zip transcription factor, acts downstream of mitogen-activated protein kinase (MAPK, extracellular signal-regulated kinase 1/2) to up-regulate cell proliferation and tumorigenesis." "In addition, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, Spz1 induced cell...
Source: Drug Week (2005-08-26)
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