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Antimicrobials
Antimicrobial peptides analyzed, polysaccharide interaction clarified
August 26th, 2005
Recent research from the United States published in the journal Peptides has reported on the interaction of antimicrobial peptides with bacterial polysaccharides from lung pathogens. "The interaction of two cathelicidin antimicrobial peptides, LL-37 and SMAP-29, with three bacterial polysaccharides, respectively, produced by Pseudomonas aeruginosa, Burkholderia cepacia and Klebsiella pneumoniae, was investigated to identify possible mechanisms adopted by lung pathogens to escape the action of innate immunity effectors," wrote Y. Herasimenka and colleagues, University of Trieste. "In vitro assays indicated that the...
Source: Drug Week (2005-08-26)
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