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Antimicrobials
Peptides may attenuate lung damage associated with cystic fibrosis
August 26th, 2005
Certain antimicrobial peptides may attenuate lung damage associated with cystic fibrosis. According to researchers in the United States and Canada, "Greater than 90% of lung infections in cystic fibrosis (CF) patients are caused by Pseudomonas aeruginosa, and the majority of these patients subsequently die from lung damage. Current therapies are either targeted at reducing obstruction, reducing inflammation, or reducing infection." "To identify potential therapeutic agents for the CF lung," stated L.J. Zhang and colleagues, "150 antimicrobial peptides consisting of three distinct structural classes were screened against mucoid and...
Source: Drug Week (2005-08-26)
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