Drug Week
Susan Hasty, Publisher
Table of Contents . . . September 9th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Cancer Therapy - Two additional sites initiated for phase II ADH-1 trial
Generic Drugs - U.S. FDA approves generic equivalent to topical suspension for fungal infections
HIV/AIDS Therapy - Company updates development of fixed-dose regimen of Truvada and Sustiva
Hemophilia - Data for Advate confirm safety and efficacy in hemophilia A patients
Kidney Disease - Phase III program for ferumoxytol modified in IV iron replacement therapy
Acetylcholine Receptors - Nicotinic receptors analyzed, regulatory roles defined
Acid Reflux - Esomeprazole and lansoprazole gastric acid suppression compared
Acinetobacter Baumannii - Risk factors identified for carbapenem-resistant A. baumannii outbreak
Acute Myeloid Leukemia - Antiangiogenic treatment with endostatin successfully fights AML
Adenosine Receptors - Immune synapse costimulatory signals analyzed, mediatory factors revealed
Adolescent Health - Challenges to vaccinating adolescents outlined
Atherosclerosis - Researchers' work adds to atherosclerosis body of knowledge
Adrenal Tumors - Woman diagnosed with adrenal tumor and congenital adrenal hyperplasia
Alcohol Abuse - Targeting melanocortin receptors may provide alcohol abuse treatment
Allergies - Allergic encephalomyelitis examined, T regulatory cell suppression clarified
Allergies - Enrolment in phase II clinical trial of R112 for allergies initiated
Allergy & Immunology - MDP1 appears to be potential adjuvant for CpG DNA-based immune therapies
Allergy Medicine - Dendritic cell vaccine does not protect against allergen responses
Breast Cancer - Recent findings in breast cancer provide new insights
Allergy Medicine - Extracts from Butterbur are an effective nondrowsy treatment for "hay fever"
Alzheimer Disease - Alzheimer disease-causing mutations studied, role of Abeta42 production revealed
Alzheimer Disease - Fibrillar beta-amyloid peptide examined, associated proteins identified
Alzheimer Disease - Gamma-secretase complex studied, characterization reported
Alzheimer Disease - New research in the area of Alzheimer disease detailed
Alzheimer Disease - Phase 1 clinical trial of treatment for Alzheimer disease initiated
Breast Cancer - Reports add new data to breast cancer research
Amyloid Beta Proteins - Anxiolytic agent examined, effect on amyloid beta neurotoxicity defined
Amyotrophic Lateral Sclerosis - Company receives correspondence from FDA concerning phase II arimoclomol study
Amyotrophic Lateral Sclerosis - Recent findings in amyotrophic lateral sclerosis provide new insights
Anemia - Long-term outcome of treatment of anemia with erythropoietin and G-CSF assessed
Anesthesia - Pharmaceutical company launches Web site for anesthesiologists
Aneurysms - Hospital offers minimally invasive treatment for thoracic aortic aneurysms
Breast Cancer - Researchers publish new studies and findings in the area of breast cancer
Angina - Action of nitroglycerin for chest pain may place some patients at risk
Angiography - Multislice CT angiography is noninvasive diagnostic procedure
Angiology - New data illuminates research in angiology
Angioplasty - Outpatient PTCA is safe and feasible for many in a routine population
Angiotensin - During ACE inhibition ANG-(1-7) can be stimulated by sodium restriction
Anthrax - Studies advance knowledge in anthrax research
Cancer Therapy - Research add new data to cancer therapy body of knowledge
Anti-Infectives - Colistin effective against multiresistant Gram-negative bacteria
Anti-Infectives - Novel des-F(6)-quinolone active against resistant staphylococci
Antioxidant - Flavonoids may promote cell survival as potent antioxidants
Antiproliferative Activity - Lamprey gonadotropin-releasing hormone III inhibited breast cancer cell growth
Apoptosis - Chlamys farreri polypeptide studied, apoptotic effects defined
Apoptosis - Apoptosis induced in prostate cancer cells by pachymic acid from Poria cocos
Cancer Therapy - Studies add new findings to cancer therapy body of knowledge
Apoptosis - Death receptors/Fas/TRAIL receptors involved in osteoclast apoptosis
Apoptosis - Novel polysaccharide induced apoptosis in HL-60 cells
Apoptosis - PINCH-1-integrin analyzed, importance in renal glomerular regulation revealed
Arthritis Therapy - Clinical pharmacokinetics of TNF antagonists reviewed
Aspirin - Low-dose aspirin increases aspirin resistance in patients with CAD
Asthma - Asthma attack analyzed, bronchial exudate of serum proteins clarified
Cardiology - Reports advance knowledge in cardiology research
Astrocytes - Astrocyte fatty acid incorporation studied, effect of synuclein clarified
Astrocytomas - Novel platinum(IV) compound with anticancer properties discussed
Atherosclerosis - Antioxidant NAC can reduce atheroma progression
Atherosclerosis - Reports describe recent advances in atherosclerosis research
Atrial Fibrillation - Guidelines focus on postoperative atrial fibrillation
Diabetes Therapy - Research in diabetes therapy provides new insights
Attention Deficit Hyperactivity Disorder - Study finds genes may predict response to ADHD medication
Awards - IDX announces winners of 2005 Carecast Customer Innovation Awards
Awards - Macugen pegaptanib sodium injection named Innovative Pharmaceutical Product 2005
Awards - Producer of consumable biological products receives Technology & Business Award
BK Virus - The role of BK virus in cancer and autoimmune disease continues to be debated
Bacterial Infection - PNA exemplifies the great potential of this class of antibacterial agents
Diabetes Therapy - Researchers publish new studies and findings in the area of diabetes therapy
Bacterial Sepsis - Antimicrobial peptide WLBU2 has potential application against P. aeruginosa
Bacterial Vaginosis - To understand BV, more research is needed on vaginal flora, related issues
Bacteriology - Disease bacteria sense antimicrobials and initiate a counter-defense
Bacteriology - U.S. FDA approves levofloxacin tablets to treat acute bacterial sinusitis
Benign Prostatic Hyperplasia - Phase 3 trial initiated in Europe for treatment of benign prostatic hyperplasia
Benzene Exposure - Lymphotoxicity due to benzene not mediated through diminished thymus function
Gynecology - Reports advance knowledge in gynecology research
Benzene Toxicity - Advances in genotyping may elucidate toxic effects of benzene on stem cells
Beta-Amyloid - Neuroinflammation and dysfunction studied, role of human beta-amyloid defined
Biomedical Engineering - Transgenic rabbits producing human antibodies generated by biopharma company
Biotechnology - CombiMatrix launches DNA CustomArray DNA Synthesizer for microarrays
Bladder Cancer - Company gets U.S. FDA clearance to initiate Chemophase clinical trial
Blood Pressure - Doxazosin controls hypertension and albuminuria in diabetic patients
Oncology - Recent findings in oncology provide new insights
Blood Safety - System removes transmissible spongiform encephalopathy during plasma separation
Bone Marrow - Dose of CsA prolonged relapse rate in childhood ALL after bone marrow transplant
Bone Marrow Transplantation - NK-KIR transcript kinetics correlate with acute GVHD occurrence after ABMT
Brain Cancer - Combined gene therapy eliminates glioblastoma multiforme in lab studies
Breast Cancer - AmpArray profiled expression of ABC transporters in a drug-resistant cell line
Breast Cancer - Chemotherapy safety evaluated for breast cancer during pregnancy
Oncology - Recent studies add new data to oncology research
Breast Cancer - Findings in breast cancer provide new insights
Breast Cancer - Older women fare favorably with conservative breast cancer treatment
Breast Cancer - Postoperative loco-regional radiation therapy treated breast cancer
Oncology - Researchers publish new studies and findings in the area of oncology
Breast Cancer Vaccine - Expression of SIVA-1 protein enhances apoptosis in breast cancer cells
Buruli Ulcer - Rifampin-streptomycin regimen inhibits mycobacterial growth
Business & Finance - Biopharma company announces second quarter 2005 results
Business & Finance - Biopharma company reports Q2 2005 financial results, clinical trial outcomes
Business & Finance - Biopharma company reports results for second quarter of fiscal 2005
Oncology - Researchers report details of new studies and findings in the area of oncology
Business & Finance - Bioscience company reports second quarter net loss of $4.9 million
Business & Finance - Biotechnology company reports financial and operational results for 2Q
Business & Finance - Corlux maker announces second quarter net loss of $4.1 million
Business & Finance - Gene-transfer company reports Q2 financial results, updates GENASIS trial
Business & Finance - Pharmaceutical company reports Q2 2005 financial and operating results
Business & Finance - Pharmaceutical company reports loss of $0.22 per share
Osteoporosis - Researchers detail new studies and findings in the area of osteoporosis
Business & Finance - Pharmaceutical company reports second quarter 2005 financial results
Business & Finance - Pharmaceutical company reports second quarter and 6 month financial results
Business & Finance - Protein-focused bioscience company reports Q2 revenue of $7.5 million
Business & Finance - Therapeutics development company gives financial results, corporate update
Business Update - Agency that named Viagra and Prozac brands Hythiam's Prometa protocols
Business Update - Biopharma company announces payments for MMH Malarex treatement
Proteomics - Researchers provide details of new studies and findings in the area of proteomics
Business Update - Biopharma reports second quarter 2005 financial results
Business Update - Biopharmaceutical company announces restructuring of operations and finances
Business Update - Biopharmaceutical firm amends facility lease
Business Update - Biotech company adds to scientific team, moves headquarters
Business Update - Biotech company adopts direct-to-consumer advertising principles
Business Update - Biotech company and SB Biosciences enters distribution agreement
Virology - Reports advance knowledge in virology research
Business Update - Biotech company retains investor relations service
Business Update - Biotherapy company, BBI sign development agreement for alpha-1 antitrypsin test
Business Update - Cialis maker reports results for 2005 second quarter
Business Update - Company announces amended agreement with Merck & Co. regarding antidepressants
Business Update - Company gets NIH grant for in silico assessment of drug metabolism and toxicity
Business Update - Company selected to process donations for cancer research
Virology - Reports describe recent advances in virology research
Business Update - Diagnostic testing company signs agreement with California, acquires LabOne
Business Update - Enzyme company, Baxter expand relationship to include European Union
Business Update - GI disorders-focused company reports second quarter 2005 financial results
Business Update - Healthcare products company announces acquisition, financial results
Business Update - Healthcare services management company announces second quarter results
Business Update - Icagen reports second quarter 2005 financial results
Virology - Studies add new findings to virology body of knowledge
Business Update - ImmunoGen reports fourth quarter and fiscal year 2005 financial results
Business Update - Indevus announces third quarter fiscal 2005 results
Business Update - Medco to provide pharmacy benefit management services to state of New Hampshire
Business Update - Pathways Solution announced at Drug Discovery Technology conference
Business Update - Vitamins, supplements company agrees to sell MonoSol Rx OTC drug, vitamin strips
Camptothecin - Chemotherapy scheduling altered effect of histone deacetylase inhibitors
Cancer Prevention - Non-steroidal anti-inflammatory drugs used for prevention of cancer
Cancer Research - Genomics company and Washington University collaborate on cancer biomarkers
Cancer Therapy - Adult-type soft tissue sarcomas in pediatric patients analyzed
Cancer Therapy - Cancer stabilization induced with targeted polymers
Cancer Therapy - Cepharanthine enhanced sensitivity of anticancer agents in K562 cells
Cancer Therapy - Data advance knowledge in cancer therapy research
Cancer Therapy - Flavopiridol shows promise as an anticancer treatment
Cancer Therapy - Prognostic factors of advanced synovial sarcoma identified
Cancer Therapy - Spin-labelled nitrosourea reduces CCNU-induced oxidative stress
Cancer Therapy - U.S. NIH awards grant for preclinical development of Talotrexin in combo therapy
Cancer Therapy - Validity of adjuvant chemotherapy for stage II colorectal cancer assessed
Cancer Vaccine - Carbohydrate vaccines as immunotherapy for cancer reviewed
Cancer Vaccine - Co-stimulation of antigen-presenting cells induced high avidity CTLs
Cancer Vaccine - Cytotoxic t cell targeting sensitizes malignant glioma to chemotherapy
Cancer Vaccine - Function of tumor-specific T lymphocytes more important than numbers
Cancer Vaccine - Method developed to screen for potential antigens for cancer vaccines
Cancer Vaccine - Method to target B lymphoma cells to antigen-presenting cells developed
Cancer Vaccine - Novel CTL epitopes derived from two cancer germline genes identified
Cancer Vaccine - Peptide disables mitochondrial function in HER-2-positive cancer cells
Cancer Vaccine - Phase 1 study of TNF-alpha AutoVaccIne in metastatic cancer reported
Cancer Vaccine - Promising therapeutic approaches to vaccination for cancer reviewed
Cancer Vaccine - Tumor antigen-specific T helper cells in cancer immunotherapy reviewed
Cancer Vaccine - Tumor-associated carbohydrate antigens are avenue for cancer prevention
Cancer Vaccine - Tumor-reactive CD8+ T cells confer superior antitumor immunity
Cancer Vaccine - Vaccine induces autoantibodies to prostate-specific membrane antigen
Carcinogenesis - UGT1A1 polymorphisms determined dietary carcinogen detoxification in the liver
Cardiac Surgery - Neurologic monitoring enables cardiac surgical teams to prevent brain injury
Cardiac Transplantation - Caspase-3 inhibition may be useful strategy for preventing graft CAD
Cardiology - Diovan approved for new indication
Cardiology - First of two pivotal phase 3 studies of regadenoson met its primary endpoint
Cardiology - New findings in the area of cardiology detailed
Cardiomyocytes - CGRP has different mode of action on developing cardiomyocytes
Cardiopulmonary Bypass - Plasma cortisol levels with maximal anti-inflammatory effects determined
Cardiovascular Disease - DNA vaccine with receptor coding plasmids impair cardiac function
Cardiovascular Disease - High risk patients are best served by aggressive cholesterol-lowering therapy
Cardiovascular Research - Cardiac cycle modulation is expressed in respiratory motor activity
Cardiovascular Research - Pathogenesis of vascular calcification in chronic kidney disease
Cardiovascular Research - Study provides insights into possible mechanisms of TMP in the vascular system
Cardiovascular Risk Factors - Inflammatory component of CV disease is reversible with smoking cessation
Cell Therapy - Mesenchymal stem cells support the expansion of irradiated CD34+ cells
Cervical Cancer - Chemotherapy compounds affected chemosensitivity of cervical cancer cells
Cervical Carcinoma - Differing regimens of neoadjuvant chemotherapy compared
Chemoresistance - Dihydropyridines and pyridines counteracted multidrug resistance
Choline - Choline intake may reduce cardiovascular disease risk
Chronic Obstructive Pulmonary Disease - Protective effect of being female is lost in COPD patients
Chronic Obstructive Pulmonary Disease - Study shows benefits of inhaled corticosteroids for COPD
Cisplatin - Novel platinum (IV) complexes induced rapid tumor cell death in vitro
Clinical Trials - Biopharma company and PharmAthene announce IND filing with U.S. FDA for Valortim
Clinical Trials - Clinical trials of SCT in multiple sclerosis are currently premature
Clinical Trials - EDC in clinical trials slow to catch on, company says; more training needed
Clinical Trials - Trial design company announces East 4, EastSurv, and EastAdapt modules
Colitis Therapy - Anti-inflammatory activity of Resolvin E1 elucidated
Collaborations - Agreement signed with Pepgen for drug development
Collaborations - Alliance formed to develop, commercialize phase II antibody products
Collaborations - Companies collaborate to codevelop DNASIS MAX and Visual Cloning
Collaborations - Company collaborates with Imperial College for study of antimicrobial agent
Collaborations - Company expands ion channel cell-line capabilities through agreement with Wyeth
Collaborations - Two-year agreement signed for Magnevist magnetic resonance contrast media
Colon Cancer - Dietary polyphenol ellagic acid deemed potent inhibitor of hOAT1
Colon Cancer - Increased carnitine-dependent fatty acid uptake induced colon cancer apoptosis
Colon Cancer Vaccine - Oral vaccine induces immune responses against carcinoembryonic antigen
Colorectal Cancer - Chemotherapy permitted resection of metastatic colorectal cancer
Colorectal Cancer - Histamine receptor antagonists could lower incidence of colorectal adenomas
Complementary & Alternative Medicine - Efficacy of acupuncture to relieve cancer-related pain evaluated
Complementary & Alternative Medicine - Garlic oil and DDB have a hepatoprotective effect while lowering plasma lipids
Complementary & Alternative Medicine - Possible toxic effects of blackseed therapy identified
Congenital Heart Disease - Report describes radiofrequency catheter ablation for managing arrhythmias
Corneal Injury - Thymosin-beta 4 treats severe inflammation-mediated corneal injuries
Crohn Disease - Published study suggests Xifaxan may be useful in treating Crohn disease
Cryptococcus Neoformans - G. mellonella moth used to study Cryptococcus neoformans pathogenesis
Cystic Fibrosis - IgE serum levels of limited value for guiding therapy in CF patients with ABPA
DNA Vaccine - Cross-linked small polyethylenimines deliver DNA efficiently to cells
DNA Vaccine - Naked DNA encoding MCP-1 and RANTES protects against renal injury
Dengue Fever - Dengue virus replication analyzed, nitric oxide-mediated suppression shown
Dengue Fever - Increasing Dengue hemorrhagic fever in Brazil not associated with new genotypes
Depression - Antidepressant paroxetine linked to higher rate of suicide attempts in adults
Depression - Study explores why minorities with mood disorders face dangerous misdiagnosis
Depression Therapy - Estrogen augmentation of antidepressants in perimenopausal depression examined
Depression Treatments - Clinical trials reveal sex differences in antidepressant response
Dermatology - Concurrent use of commercially available insect repellent and sunscreen examined
Dermatology - Data advance knowledge in dermatology research
Dermatology - Effects of psoriasis treatment reported
Dermatology - Successful scleromyxedema therapy reported with intravenous immunoglobulins
Diabetes Epidemiology - Long-term sucrose-drinking causes increased body weight and glucose intolerance
Diabetes Risk Factors - Effect of antipsychotic drug use on diabetes risk estimated
Diabetes Therapy - Chlorella exerts hypoglycemic effects in diabetic mice
Diabetes Therapy - Basal pulsatile insulin does not improve insulin action
Diabetes Therapy - Findings in diabetes therapy provide new insights
Diabetes Therapy - Hyperglycemia has short-term adverse effects on myocardial blood flow
Diabetes Therapy - Liraglutide improves glycemic control and body weight in diabetes
Diabetes Therapy - N-acetylcysteine and taurine protect against oxidative stress
Diabetes Therapy - Oral meds good for controlling type 2 diabetes in children
Diabetes Therapy - Pioglitazone benefits liver in patients with type 2 diabetes
Diabetes Therapy - Pioglitazone better than metformin for improving insulin sensitivity
Diabetes Therapy - Pioglitazone, metformin, and glimepiride reduce blood glucose equally
Diabetes Therapy - Thiazolidinediones may improve clinical care in type 2 diabetes
Diabetes Vaccine - CpG ODN have limited effect in preventing type 1 diabetes in NOD mice
Diabetic Nephropathy - Podocyte injury is no latecomer in diabetic nephrology
Diagnostics - HPLC monitors plasma concentrations of antituberculosis drugs during therapy
Diagnostics - Medical device company announces FDA approval of glucose monitoring system
Diagnostics - Serum matrix metalloproteinase-9 may be a prognostic marker
Diet & Nutrition - Limiting cholesterol decreases lecithin intake in Japanese people
Diet & Nutrition - Nutrition may reduce symptoms of peripheral vascular disease
Diet & Nutrition - Soy isoflavones may help prevent bone loss and cancer
Diet & Nutrition - Vitamin E usage in cosmetic and clinical dermatology reviewed
Disease Associations - Chronic kidney disease studied, pathogenesis of vascular calcification defined
Disease Associations - Gingival epithelial cells studied, response to bacterial challenge clarified
Disease Associations - Renal epithelial transdifferentiation studied, role of Rho-GTPase defined
Disease Associations - SARS-Cov S1 protein analyzed, molecular docking model developed
Drug Delivery - Drug Master File submitted to U.S. FDA for drug delivery technology
Drug Delivery - Ultrasound-assisted atomizer produces drug-loaded microparticles
Drug Development - Antimicrobial activities of Mannich bases and derivatives determined
Drug Development - Biotech company starts process for manufacture of ThromboView
Drug Development - Differences in biopharmaceutical information in E.U. and U.S. examined
Drug Development - Drug prices do not reflect development time and government investment
Drug Development - Enrollment completed for phase III trial of pexelizumab
Drug Development - GMP materials pass QC release for phase I/II trial in cervical cancer
Drug Development - High throughput screening services company awarded phase II SBIR grant
Drug Development - New molecules help make stable catalysts that work at room temperature
Drug Development - Novel neopeptide antibiotics show promise
Drug Development - Novel parenteral carbapenem active against nosocomial pathogens
Drug Development - Novel phenylmethanone protects against beta-amyloid neurotoxicity
Drug Development - Pharma company expands early clinical research capacity in Nebraska
Drug Development - Pharmaceutical company to conduct ADHD clinical survey
Drug Development - Pharmaceutical company updates preclinical pipeline
Drug Development - Pharmacy announces resignation of COO
Drug Development - Phase I trial initiated for Venezuelan equine encephalitis vaccine candidate
Drug Development - Researchers' data advance drug development research
Drug Development - Results published for amyotrophic lateral sclerosis therapy
Drug Development - Rv3806c-encoded enzyme is a target for the development of new tuberculosis drugs
Drug Development - Study with bosentan shows reduction of new digital ulcers in sclerosis patients
Drug Resistance - Imipenem effective against tuberculosis in mice and humans
Drug Utilization - Pharmaceutical assistance in public primary care in Brasilia evaluated
Embolism - Clinical outcome of patients with venous thromboembolism revealed
Encephalitis - Phase 3 clinical trials for Japanese encephalitis vaccine approved in Europe
Endothelial Cell - Autologous endothelial cells mat be beneficial in treating vascular injury
Entamoeba Histolytica - Entamoeba histolytica from same geographic region genetically diverse
Environmental Health - More research needed on link between blood lead level and risk of asthma
Epstein-Barr Virus - CD8 cell epitopes specific for EBV immediate-early transactivator Rta identified
Epstein-Barr Virus - Findings in epstein-barr virus provide new insights
Epstein-Barr Virus - Impact of latent EBV infection on outcome of Hodgkin lymphoma examined
Erythromycin - Effect of erythromycin might be due to inhibition of MMP-2 in VSMCs
Familial Hypercholesterolemia - Colestimide effective alone or with atorvastatin
Finance - $30M initiative launched to propel multiple sclerosis research, care
Finance - ASP announces second-quarter operating results
Finance - Alferon maker reports net loss decreased by 36% in second quarter
Finance - Biomedical company reports 22% increase in contract signings
Finance - Biopharma announces second quarter net loss of $9.3 million
Finance - Biopharma company announces financial results
Finance - Biopharma company announces second quarter 2005 financial results
Finance - Biopharma company reports financial results
Finance - Biopharmaceutical company announces financing
Finance - Biopharmaceutical company reports Q2 2005 financial results
Finance - Biopharmaceutical firm records quarterly loss of $6M
Finance - Biopharmaceutical firm reports loss of $0.11 per share
Finance - Biopharmaceuticals firm records net loss of $0.26 per share
Finance - Biotech company announces private placement
Finance - Biotech company gets research grant within BioChancePLUS program
Finance - Biotech company increases share capital
Finance - Biotech company records net loss of $0.12 per share
Finance - Biotech company reports earnings per share of $0.02
Finance - Biotech company reports income of $0.27 per share
Finance - Biotech company reports quarterly net loss of $0.33 per share
Finance - Biotech research company posts record Q2 revenue
Finance - Biotechnology company reports second quarter 2005 results
Finance - Branded pharmaceutical company reports second quarter 2005 financial results
Finance - CNS-focused company announces second quarter 2005 results
Finance - California-based pharmaceutical company reports Q2, year-to-date 2005 results
Finance - Cancer-focused bioscience company announces 4,500,000-share stock offering
Finance - Cancer-focused company reports second quarter revenue of $58,000
Finance - Cancer-focused pharmaceutical company reports Q2 2005 financial results
Finance - Cancer-focused pharmaceutical company updates progress, reports Q2 results
Finance - Carbohydrate compound developer reports second quarter results
Finance - Clinical management company reports loss of $0.10 per share
Finance - Company focused on transdermal science reports Q2 2005 results, business update
Finance - Defibrillator maker reports 52.6% gross profit margin
Finance - Drug developer reports earnings of $0.78 per share
Finance - GR system developer reports $7 million net loss for second quarter
Finance - Gene-based therapies company reports second quarter 2005 financial results
Finance - Genomics-based drug-discovery company reports Q2 net loss of $9.7M
Finance - Grant awarded for magnetic resonance angiography
Finance - Grant intended to fund development of Alzheimer diagnostic
Finance - Healthcare products maker declares dividend of $0.06 per share
Finance - Infection and contamination prevention company announces financial results
Finance - Life science and high technology company declares quarterly dividend
Finance - Life-sciences corporation reports financial results
Finance - Maker of drug discovery systems reports second quarter total revenue up 30%
Finance - Medical device company announces first quarter gross margin of 70%
Finance - Nucleic acids company reports second quarter 2005 results
Finance - Pain drug developer posts loss of $0.35 per share
Finance - Personalized medicine company completes $17 million financing
Finance - Pharma company announces financial results
Finance - Pharma company announces second quarter 2005 financial results
Finance - Pharma company reports financial results
Finance - Pharma company reports second quarter 2005 results
Finance - Pharma firm reports 22% increase in world sales
Finance - Pharma firm reports loss of $0.10 per share, anti-nausea drug trial update
Finance - Pharmaceutical company closes public offering of common stock
Finance - Pharmaceutical company developing anticancer agents reports Q2 2005 results
Finance - Pharmaceutical company reports $0.12 diluted earnings per share
Finance - Pharmaceutical company reports Q2 2005 financial results
Finance - Pharmaceutical company reports improved financial results
Finance - Pharmaceutical company reports loss of $0.31 per share
Finance - Pharmaceutical company's revenues decrease 10.8%
Finance - Pharmaceutical firm announces initial public offering
Finance - Pharmaceutical firm prices common stock offering
Finance - Pharmaceutical firm records earnings per share of $0.38
Finance - Pharmaceutical firm records net loss of $0.15 per share
Finance - Pharmaceutical firm reports $0.34 per share net loss
Finance - Pharmaceutical firm reports 9% increase in sales
Finance - Pharmaceutical firm reports loss of $0.24 per share
Finance - Prestara maker reports Q2 revenues of $1.7M and a net loss of $2.9M
Finance - Provider of products for genetics market reports Q2 2005 financial results
Finance - Sales and marketing services provider announces financial results, new hire
Finance - Supplier of biological materials announces Q3 2005 financial results
Finance - Therapeutics company announces second quarter 2005 results
Finance - Vaccine maker reports second quarter revenue of $1.2 million
Folic Acid - Folic acid is effective supplement that targets large artery stiffness
Fonconi Anemia - Hypoxia-reoxygenation induces premature senescence in Fanconi anemia BM cells
Gastric Cancer - Cytotoxic effects of pemetrexed in gastric cancer cells discussed
Gastric Cancer - Weekly oxaliplatin plus fufox regimen used as first-line treatment
Gastric Infection - Novel synthetic agent active against H. pylori
Gastric Infection Therapy - Novel broth microdilution assay identifies anti-Helicobacter agents
Gastrointestinal Cancer - GIST metastasis during imatinib mesylate treatment characterized
Gastrointestinal Stromal Tumor - Pharma company submits NDA for Sutent to FDA
Gene Research - Company expands RNAi product line to 50,000 in frozen or plasmid DNA form
Gene Silencing - Researchers describe findings in gene silencing studies
Generic Drugs - Pharma company establishes generic business
Generic Drugs - Pharma company receives approval to market Sumatriptan Succinate Tablets
Generic Drugs - Pharmaceutical company given approval for generic cephalosporin antibiotic
Genetics & Genomics - Fast-growing market for SNPs products continues to grow
Geriatrics - Treatment of small cell lung cancer in the elderly evaluated
Glioblastoma Multiforme - Copper depletion is an ineffective strategy against GBM
Glioblastoma Vaccine - Dendritic cell vaccine in glioblastoma induces T-cell responses
Grants - Association funds collaborative drug screening effort for ALS therapies
Green Tea - Proteasome-inhibitory and apoptosis-inducing potencies of (-)-EGCG examined
Gynecology - Data advance knowledge in gynecology research
HIV Diagnostics - Rapid HIV diagnostic test eliminates human error
HIV/AIDS & Acute Coronary Syndrome - Report highlights acute coronary syndrome in HIV-infected patients
HIV/AIDS Bone Health - Bone mineral content of HIV-infected children comparable to healthy children
HIV/AIDS Complications - Body changes evaluated in HIV-infected women
HIV/AIDS Drug Adherence - Complete HAART adherence crucial in maintaining virological response over time
HIV/AIDS Drug Development - Antifungal peptide from ground beans inhibitory toward tumor cells and HIV-1 RT
HIV/AIDS Drug Resistance - NRTI/NNRTI resistance more frequent than PI when resistant to 2-3 ARV classes
HIV/AIDS Drug Resistance - Studies add new findings to HIV/AIDS drug resistance body of knowledge
HIV/AIDS Drug Side Effect - Efavirenz diminishes antilipid efficacy of HMG-CoA reductase inhibitors
HIV/AIDS Encephalitis - E2F4 changes may contribute to altered neuronal morphology or survival in SIVE
HIV/AIDS Epidemiology - Consistent clade homogeneity of HIV strains circulating in Mozambique
HIV/AIDS Neuropathology - Neuropathologies of HIV infection identified by forensic autopsy
HIV/AIDS Pathogenesis - Increased levels of anti-HspBP1 IgG are prevalent in HIV infected subjects
HIV/AIDS Pathogenesis - Researchers' data advance HIV/AIDS pathogenesis research
HIV/AIDS Risk Factors - SDF-1 3'A allele increases AIDS risk
HIV/AIDS Therapy - Vascular changes greater in HIV-infected children exposed to protease inhibitors
HIV/AIDS Tuberculosis Coinfection - Elevated cytokines contribute to continuous HIV viremia during TB coinfection
HIV/AIDS Vaccine - Mucosal alloimmunization inhibits SIV infectivity
HIV/AIDS-Associated Arthritis - Arthritis causally related to HIV infection in children
HIV/AIDS-Associated Periodontal Disease - Active human cytomegalovirus reactivation triggers periodontal disease activity
HIV/AIDS-Related Cancer - Cancer survival improving in persons with HIV/AIDS
Hashimoto Thyroiditis - Hormone therapy regimen enables normal adult height
Healthcare Costs - Cost effectiveness policies hinder progress toward effective global TB control
Healthcare Coverage - Prescription assistance organization launches South Dakota chapter
Healthcare Coverage - Report comparing Minnesota health plan quality released by coalition
Heart Disease - Interest increases in interventions that improve health-related QoL
Helicobacter Pylori - Antibody role in colonization and infection by H. pylori reviewed
Hematology - Reports advance knowledge in hematology research
Hemophilia A - Trial of investigational albumin-free recombinant drug for hemophilia A begun
Hemophilia Therapy - Guidelines for recombinant activated factor VII in bleeding released
Hepatitis B Vaccine - HBV vaccine questionable in patients receiving lamividine post liver transplant
Hepatitis B Virus - Company announces end of patient dosing in HepeX-B hepatitis B phase II trial
Hepatitis C Therapy - Health Canada approves study of celgosivir compound in HCV non-responders
Hepatitis C Virus - Discovery team advances nonnucleoside compound in preclinical development
Hepatitis C Virus - Further study of the adiponectin/insulin resistance/HCV infection triad needed
Hepatitis C Virus - HCV treatment causes changes in tear dynamics and changes on ocular surface
Hepatitis C Virus - Tarvacin phase I hepatitis C virus trial initiated
Hepatitis Pathogenesis - Hepatitis B virus X protein up-regulates lymphotoxin-alpha expression
Hepatocellular Carcinoma - Percutaneous ethanol injection is safe and effective as first-line option
Hepatology - Hepatotoxicity examined, role of cytochrome P450 2E1 induction defined
Herpes Vaccine - Adjuvants for DNA vaccine against herpes simplex virus compared
Hormones - Epithelial cell T-bet expression studied, role of female steroid hormones shown
Hospitals - Patient profiles from palliative care team compared to palliative care units.
Human Papillomavirus - HPV escapes recognition through phosphoinositide 3-kinase activation
Hypercholesterolemia - Reasons for suboptimal treatment of hypercholesterolemia are complex
Hyperglycemia - Renally adjusted gatifloxacin therapy causes severe hyperglycemia
Hypertension - BH4 may prevent development of hypertension and myocardial hypertrophy
Hypertension Therapy - Results of STRATHE study released
Hypertriglyceridemia - TRbeta may be a potential target for treatment of hypertriglyceridemia
Hypoxia - Astrocyte epoxygenase induction examined, hypoxia inducible factor implicated
Immunization - Anaplasma MSP2-specific T cells disappear rapidly after challenge
Immunodeficiency - Immunoglobulin therapy needs standards of practice
Immunology - NK-dependent DC maturation mediated by TNF-alpha and IFN-gamma
Immunotherapy - ISA247 may suppress diverse immune functions more potently than cyclosporine
Implantable Cardioverter Defibrillators - QRS duration was not useful to predict ICD benefit
Infections - LPS-induced iNOS expression studied, role of agrochemicals revealed
Infections - Role of gut macrophages in mice orally contaminated with scrapie or BSE
Infectious Diseases - Lyme disease group forms scientific advisory board, invites grant applications
Influenza - Pharmaceutical company receives grant to test influenza drug candidate
Influenza - Surveillance, targeted use of antivirals, could help prevent flu pandemic
Influenza Epidemic - Timing of influenza and bird flu epidemics calculated
Influenza Vaccine - Respiratory vaccination of mice against influenza virus examined
Information Technology - Companies form strategic alliance to provide drug discovery software system
Information Technology - Drug cost comparison Website identifies top 20 drugs sought on Internet
Information Technology - Drug discovery informatics provider launches electronic laboratory software
Information Technology - GlaxoSmithKline expands installation of videoconferencing systems
Information Technology - IT product launched for pharmacokinetic analysis
Information Technology - Proteomics and genomics company selects IBM TurboWorx for data management
Insulin Resistance - Inhibition of p38 MAP kinase improves glucose uptake in adipocytes
Insulin Therapy - Inhaled insulin for diabetes reviewed
Interferon - CD4+ T-lymphocyte migration studied, signal cascade stimulation revealed
Interleukin-6 - IL-6 effects on cardiomyocyte hypertrophy could be mediated by Ang II
Ischemia - Endothelin studied, effects of overexpression clarified
Kaposi Sarcoma - HHV8 is a useful tool in confirming the diagnosis of cutaneous Kaposi sarcoma
Kaposi Sarcoma-Associated Herpesvirus - KSHV may be sexually transmitted among Cuban population
Kidney Cancer - Differing combination treatments for genito-urinary tract cancer compared
Kidney Disease - Study evaluates treatment for patients with anemia from chronic kidney disease
Kidney Failure - Researchers explore reasons for complications with kidney failure patients
Klebsiella Pneumoniae - Carbapenem-resistant K. pneumoniae rapidly spreading in New York City
Lassa Fever Vaccine - New vaccine for prevention of Lassa fever developed
Legionellosis - L. pneumonia infection caused by exposure to contaminated bath water
Leishmaniasis Vaccine - DNA vaccine protects against Leishmania donovani
Leprosy - Leprosy diagnosis should be considered in patients who work/travel in tropics
Leukapheresis - Large-volume leukapheresis safe/effective in low-weight pediatric patients
Leukemia - AML patients with Down syndrome showed high cure rate with AML-BFM therapy
Leukemia - Risk of AML and MDS linked to adjuvant epirubicin for early breast cancer
Leukemia Vaccine - Epitopes of receptor for hyaluronic acid-mediated motility identified
Lipid Studies - Salvianic acid A may have potential against oxidative stress processes
Liver Transplantation - Enteral donor UDCA pretreatment reduces I/R injury in rats
Lung Cancer - Amrubicin and cisplatin combined to treat extensive-stage small-cell lung cancer
Lung Cancer - Aspirin inhibited NF-kappaB activation in lung epithelial cell line
Lung Cancer - C-erbB-2 not involved in first steps of lung carcinogenesis
Lung Cancer - Findings from ALPI trial of adjuvant chemotherapy revealed
Lung Cancer - Phase 2 clinical trial of non-small cell lung cancer treatment initiated
Lung Cancer - Two designer drugs hit same lung cancer target, but only one is effective
Lung Cancer Therapy - U.S. FDA approval summary of pemetrexed for lung cancer therapy released
Lupus Erythematosus - Antiendothelial cell antibodies from lupus patients do not induce apoptosis
Lymphoma - CHOP followed by radiotherapy in large B-cell stomach lymphoma
Lymphoma - Stat3 is a therapeutic target in fight against human lymphoma
Macular Edema - Intravitreal triamcinolone improves vision in diabetic macular edema
Malaria - Plasmodium falciparum calcineurin analyzed, association with Hsp90 defined
Malaria - Plasmodium falciparum examined, ATPase activity clarified
Malaria - LANCL1 examined, recruitment during P. falciparum development clarified
Malaria - Plasmodium merozoites and infected erythrocytes studied, SURFIN identified
Malaria - Potent inhibitors of malarial plasmepsin I and II synthesized
Malaria Therapy - Possible new compound for treatment of cerebral malaria described
Malaria Vaccine - Researchers peg five peptides as candidates in designing a malaria vaccine
Market Analysis - 88% of pharma companies involve thought leaders by the end of phase II
Market Analysis - Biotech remains on a roll in July
Marketing - Genzyme Biosurgery selects PR firm to handle Seprafilm
Measles Vaccine - Window of vulnerability to measles in infants in rural Mali determined
Medical Devices - Medical device company acquires cervical nucleus-like replacement device
Melanoma - Cyclooxygenase inhibitor usage lowered risk of melanoma in high-risk patients
Melanoma - First melanoma patients complete treatment in phase I clinical trial of PV-10
Melanoma - GSTP1 and MRP1 combine to resist melanoma treatment
Melanoma Vaccine - Fusion with IL-2 enhances immunogenicity of anti-idiotypic antibody
Melanoma Vaccine - Noncanonical melanoma-associated T cell epitopes identified
Melanoma Vaccine - Vaccine targets tumor microenvironment for treatment of melanoma
Menopause - Bioidentical hormone therapy promoted for menopause
Mergers & Acquisitions - Bioscience products company acquires shares of NovAseptic
Mergers & Acquisitions - Healthcare equity firm acquires CorePharma LLC
Mergers & Acquisitions - Medical technology company acquires majority control of Rheologics Inc.
Mergers & Acquisitions - Nutraceutical company plans to merge with Strategic Healthcare Systems
Mergers & Acquisitions - Stockholders approve business combination with IDM
Microsurgery - Microvascular anastomosis may be performed in hyperfibrinogenemia
Migraine Headaches - Several conditions have been noted to be comorbid with migraine
Multicomponent Apheresis Collection - Red cell apheresis may become the collection standard
Multiple Sclerosis - Current trials in multiple sclerosis reviewed
Mycobacterium Avium - Identified M. avium gene affects invasion of intestinal epithelium
Mycobacterium Tuberculosis - Scanning electron microscopy analyzes aged Mycobacterium tuberculosis cells
Mycobacterium Vaccine - Cytokine gene expression profiles of dendritic cells described
Myeloma - Thalidomide analogs show encouraging results against multiple myeloma
Myocardial Infarction - Inspra reduces risk of early death in heart attack patients with LVSD
Myocardial Infarction - Low HRV partially mediates effect of depression on survival after acute MI
Needle Stick Injury - Accidental blood exposures among healthcare workers in West Africa assessed
Neural Migration - Cell culture model used to investigate glial-guided neuronal migration
Neural Repair - Manipulating neurogenesis may be used to repair neural circuitry
Neurodegeneration - Induced nigral degeneration analyzed, neuroprotection by iron chelator revealed
Neuroscience - Cerebellar granule and hippocampal neurons studied, GABA behavior revealed
Neuroscience - Endothelin examined, expression effects revealed
Neuroscience - Kynurenic acid production examined, role of homocysteine determined
Neuroscience - New research in the area of neuroscience detailed
Non-Hodgkin Lymphoma - Fludarabine-mitoxantrone compared with CHVP as treatment of elderly patients
Norovirus Outbreaks - Gastroenteritis outbreaks in Switzerland caused by noroviruses
Norovirus Outbreaks - Norovirus contamination found in oysters worldwide
Nosocomial Infections - Parasites underestimated in nosocomial diarrhea
Nuclear Medicine - OLINDA/EXM is second-generation software for nuclear medicine dosing
Oligodendrocytes - Asp endopeptidase studied, antigenic and processing roles defined
Oncology - Candidate agents synthesized for PET imaging of EGFR-positive tumors
Oncology - New findings in the area of oncology described
Osteoporosis - Companies announce agreement to develop new drug targeting osteoporosis
Osteoporosis - Findings in osteoporosis provide new insights
Osteoporosis - Study reveals facts about how osteoporosis therapies affect bone cell activity
Otology - New lab research may help those deafened by immune system attack
Pain Management - Cancer pain management in prisons surveyed
Pain Management - Phase III trial of bicifadine for pain following vaginal hysterectomy begins
Pain Management - Specialists using more OTC pain relievers for minor arthritis pain, survey shows
Pain Management - U.S. FDA grants second orphan status to tramadol for postherpetic neuralgia
Pancreatic Cancer - Advisory committee to review treatment for advanced pancreatic cancer
Pancreatic Cancer - Biopharma company reports second quarter 2005 financial results
Pancreatic Cancer - TPA and ATRA a potential one-two punch for cancer of the pancreas
Pancreatic Cancer - Vascular endothelial growth factor receptor promotes tumor invasion
Patents - Allowance granted for broad patent covering RNAi therapeutics
Patents - Company granted patent expanding Oxiplex technology in drug delivery, hemostasis
Patents - Patent application filed for cardiovascular technology
Patents - Patent granted for drug screening methods
Pediatric Anesthesia - Midazolam syrup superior to ketamine lollipop for premedication
Pediatric Anesthesia - Rocuronium doesn't improve intubation during halothane induction
Pediatric Cancer - Pain in pediatric oncology viewed from children's and parents' perspectives
Pediatric Cancer Therapy - Micafungin pharmacokinetics during febrile neutropenia determined
Pediatric Sarcoma - Vincristine, ifosfamide, and doxorubicin treated pediatric sarcomas
Peripheral Arterial Occlusion - Clinical trial data of chronic peripheral arterial occlusion treatment published
Peripheral Neuropathy - Company inks agreement for treatment of diabetic neuropathy with VEGF-2
Personnel - Antibody developer appoints Bo Kruse as interim CFO
Personnel - Biopharma company appoints of chief executive officer
Personnel - Biopharma company names vice president, finance and CFO
Personnel - Biopharmaceutical company announces new appointments, reports on finances
Personnel - Biosciences industry organization president resigns
Personnel - Biotech company names chief science officer
Personnel - Biotech company names new board member
Personnel - Biotechnology company announces death of board chair Richard G. Babbitt
Personnel - CUBICIN maker names Lindon M. Fellows senior VP, technical operations
Personnel - Clinical research organization adds VP operations
Personnel - Company names Scott W. Meggs senior director, corporate counsel
Personnel - Data management solutions provider names vice president marketing
Personnel - Diane J. Romza-Kutz named managing partner at healthcare-focused law firm
Personnel - Drug discovery company names Robert Castellucci vice president of quality
Personnel - Elizabeth Squiers, MD, named VP, clinical affairs, by biopharmaceutical company
Personnel - European pharmaceutical executive joins the board of TH9507 developer
Personnel - George Isham, MD, appointed to federal drug safety task force
Personnel - Peter Ladell and Peter Tombros named to board of directors
Personnel - Pharmaceutical company appoints two independent directors
Personnel - Pharmaceutical firm appoints Philip Haworth as VP of business development
Personnel - Provider of pharmaceutical care for the elderly announces executive appointments
Personnel - Robert Cooke named managing director, CEO of Australian healthcare group
Personnel - Thad Evans to succeed Joachim Szebel as head of Merck Pigments Division
Personnel - Timothy Barberich and Wayne Roe appointed to biotech company board of directors
Pertussis Vaccine - Acellular pertussis vaccines safe and effective in adolescents
Pertussis Vaccine - Clinical and economic effects of pertussis outbreaks reviewed
Pharmaceutical Research - Market research firm releases study on pharma spending
Pharmacokinetics - Methods for interspecies scaling of biliary excreted drugs compared
Pharmacology - Adrenomedullin examined, pulmonary pharmacology clarified
Pharmacology - Informed consent in pharmacogenetic clinic assessed
Phosphorylation - Na+/H+ exchanger studied, phosphorylation process clarified
Physiology - Duodenal activation of vagal afferents studied, role of PepT1 defined
Pneumococcal Disease - Chronic illness increases incidence of pneumococcal disease in adults
Polio Vaccine - Genomic analysis of vaccine-derived poliovirus strains conducted
Presenilin - Presenilin-1 mutants studied, restoration of gamma-secretase activity clarified
Prions - Studies describe new findings in prions research
Proanthocyanidin - Proanthocyanidin from grape seeds enhanced anti-tumor effect of doxorubicin
Product Licensing - Bioscience company signs license agreement for small molecule oncology compounds
Product Licensing - Cancer drugs licensed from University of Arizona Foundation
Product Licensing - License agreement with Japanese pharmaceutical co. allows selling of stem cells
Product Licensing - Medical device company enters licensing agreement with NeuroPace
Product Licensing - Observation rights agreement forged for kidney stone formation study
Product Licensing - Product license agreement signed for antihypertensive agent ARB olmesartan
Product Licensing - Proteomics company obtains rights for cancer early detection technologies
Professional Education - $1.75 million Genomics Education Matching Fund program for undergrads announced
Progenitor Cells - Human mononuclear cells differentiate to EPCs at a very low rate
Prostate Cancer - Expansion of phase II clinical trial of PI-88 for prostate cancer announced
Prostate Cancer - In vivo uptake of [11C]choline did not correlate with cell proliferation
Prostate Cancer - New class of inhibitors prevented invasion of prostate cancer cells
Prostate Cancer Vaccine - Antibody to prostate-specific membrane antigen used for cancer therapy
Proteomics - Recent findings in proteomics provide new insights
Proton-Pump Inhibitors - Study focused on proton-pump inhibitors and chest pain events
Pseudomonas Aeruginosa - Nonsterile cotton jersey causes surgical wound infections
Pulmonary Hypertension - European mutual recognition procedure for pulmonary hypertension treatment done
Receptors - Functional urotensin II receptors in human skeletal muscle myoblasts studied
Receptors - Role of spinal D1/D5 receptors in pathological pain studied
Renal Transplantation - Reports advance knowledge in renal transplantation research
Respiratory Syncytial Virus - RSV immunopathology studied, innate interferon role defined
Respiratory Tract Infections - Ketolides for community-acquired respiratory tract infections reviewed
Retinal Disease Therapy - Convective-diffusive transport of implant-released drugs characterized
Retinopathy - Data advance knowledge in retinopathy research
Retrovirus - HIV mania is a marker for clinical deterioration in AIDS
Rheumatoid Arthritis - Adalimumab plus methotrexate effective for long-standing rheumatoid arthritis
Rheumatoid Arthritis - Efficacy of Ayurvedic medicine in treatment evaluated
Rheumatoid Arthritis - Remicaid post-marketing surveillance discussed by regulatory group
SARS - Early centralization of infectious patients may reduce extent of epidemics
SARS - Infection control implemented in radiology department after SARS outbreak
SARS Outbreak - Protective measures begun during SARS outbreak reassures health care workers
Seasonal Allergic Rhinitis - Levocetirizine controls symptoms for entire pollen season
Sepsis - Therapeutic potential of recombinant human antithrombin on sepsis presented
Sexual & Reproductive Health - New magazine focused on fertility topics launched
Sexual Risk Behaviors - Alcohol intoxication associated with sexual risk behaviors in migrants in China
Sexually Transmitted Diseases - Migration contributes significantly to spread of sexually transmitted infections
Skeletal Muscle - Skeletal muscle Ca2+ release studied, role of bupivacaine enantiomers shown
Skin Cancer - CD8+ and CD4+ lymphocytes contribute to immunosurveillance against skin cancer
Skin Infections - Improved murine superficial infection model developed
Smoking Cessation - Recovering alcoholic smokers can quit second addiction
Snakebite - CroFab enters fifth year; company addresses issues relating to snakebite
Squamous Cell Carcinoma - Factors affecting survival in patients with oral cancer identified
Staphylococcal Infection - Lauric acid monoesters effective in murine MRSA model
Staphylococcus Epidemiology - Definitions yield different estimates of Staphylococcus prevalence
Statins - New findings in the area of statins described
Statins - Pravastatin induces regression of focal coronary atherosclerosis
Statins - Pravastatin reduced rate of kidney function loss
Statins - Study identified new in vivo targets of atorvastatin treatment
Statins - The nature of statin neuromyotoxicity remains unresolved
Stem Cell Aging - Cell intrinsic alterations underlie hematopoietic stem cell aging
Stem Cell Research - Bone marrow-derived side population cells can contribute to respiratory tract
Stem Cell Research - Embryonic stem cell research explored from an Islamic perspective
Stem Cell Research - Fetal liver epithelial cells with high repopulation capacity characterized
Stem Cell Research - Galanin regulates stem cell proliferation/migration/differentiation
Stem Cell Research - Growth-stimulatory effects of androgens on hematopoietic stem cells are minimal
Stem Cell Research - MRI differentiates localized/widespread neural stem cell engraftment in the CNS
Stem Cell Research - NANOG expressed in fetal gonocytes/testicular carcinoma/germ cell tumors
Stem Cell Research - Natural killer T cells fully reprogrammed by a single-step nuclear transfer
Stem Cell Research - Neural stem cells potential source of oligodendrocytes for myelin repair
Stem Cell Research - Nonribosomal landscape in nucleolus revealed by stem cell protein nucleostemin
Stem Cell Research - Sox15 & Sox2 have differential roles in transcriptional control in embryonic SCs
Stem Cell Research - Stem cell company gets support to develop drug candidate for Huntington disease
Stem Cell Research - Transplanted bone marrow cells generate new brain cells
Stem Cell Research - Various methods developed to analyze chemokinetic and chemotactic cell migration
Stem Cell Transplantation - Bone marrow stromal cell transplantation improves
Stem Cell Transplantation - Peripheral blood SCs speed neutrophil/platelet engraftment in lymphoma patients
Stents - Drug-eluting stent was associated with lower risk of restenosis
Stents - Stents are associated with exercise-induced coronary vasoconstriction
Stress - Treatment with alpha-tocopherol prevents stress-induced radical attack
Stress-Induced Fibrinogen - IL-6 reactivity was an independent predictor of stress-induced fibrin formation
Synapses - Research in synapses provides new insights
T Cells - T cell cytokine synthesis studied, endothelial cell co-stimulation revealed
Tardive Dyskinesia - Pharma company reports on MT-100 FDA meeting, Trexima NDA submission
Teratogens - Fungicide triazole-derivatives studied, common teratogenic pathway revealed
Thyroid Cancer - Risk of bone fracture due to suppressive l-thyroxine therapy assessed
Tissue Engineering - Bioactive scaffold used to regenerate nucleus pulposus tissue
Tissue Engineering - Cell-bioceramic interactions characterized via enhanced GFP-labeled MSCs
Tissue Engineering - Ectopic bone formation associated with MSCs in resorbable ceramic
Tissue Engineering - N-acetylation controls cell adhesion and degradation of chitosan films
Tissue Engineering - Scaffold developed to guide nerve tissue regeneration after transection injury
Tissue Engineering - Vascularized bone engineered from osteoblast-polyglycolic acid scaffold
Topical Microbicide - Topical penile microbicide wipe safe/effective at reducing STI-related bacteria
Transcription Factors - Transcription factor sumoylation analyzed, role of histone deacetylases defined
Transplant Medicine - Akt a target for islet transplantation strategies in diabetics
Transplant Medicine - Studies advance knowledge in transplant medicine research
Traumatic Brain Injury - Antagonism of IL-1 improves anatomical and functional outcomes
Tuberculosis Risk Factors - Smoking may increase the risk of Mycobacterium tuberculosis infection
Tuberculosis Risk Factors - Tuberculosis risk after HAART initiation higher in patients with history of TB
Tuberculosis Therapy - Antibiotic cross-resistance in Mycobacterium tuberculosis examined
Tuberculosis Vaccine - Role of TNF-alpha in pulmonary tuberculosis in guinea pig examined
Tuberculous Infection - Reactivated tuberculous infection becoming more prevalent after transplantation
Tumor Suppressor - Unique complex between bacterial azurin and tumor-suppressor protein p53 studied
Tumorigenesis - Association between hormone replacement therapy and tumor growth reviewed
Urinary Incontinence - Treatment for stress urinary incontinence cleared for marketing
Vaccine Adjuvant - Leptin promotes differentiation and survival of human dendritic cells
Vaccine Adjuvant - Vitamin E TPGS enhances immune response to nasal diphtheria vaccine
Vaccine Delivery - DNA released from dendriplexes encapsulated in PGLA nanoparticles
Vaccine Delivery - Decision-making at surface of intact or barrier-disrupted skin examined
Vaccine Vector - Interference with IL-1-signaling reduces toxicity of adenovirus vectors
Venous Thromboembolism - Data from two phase II studies for Factor Xa inhibitor presented
Ventilator-Associated Bacterial Pneumonia - Rapid ventilator-associated bacterial pneumonia identification reduces mortality
Ventricular Tachycardia - Effects of nifekalant on spiral excitations are reversed by lidocaine
Virology - Recent findings illuminate research in virology
Wilson Disease - Zinc sulphate release from lipophilic matrices characterized
Wuchereria Therapy - Efficacy of combined treatment of helminth infections examined
Yersinia - Bovine lactoferrin inhibits Yersinia-directed epithelial cell apoptosis
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