Published in Drug Week, September 9th, 2005
"The cause of the neurodegenerative process in Parkinson disease (PD) remains unclear, but evidence suggests that failure of the ubiquitin-proteasome system may play a major role in the pathogenesis of the disease. Iron is believed to be a key contributor to PD pathology by inducing aggregation of alpha-synuclein and by generating oxidative stress," wrote X. Zhang and colleagues, Wenzhou Medical College.
"Our present studies have shown that micro-injection of the proteasome...
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