Published in Drug Week, September 9th, 2005
"The presence of nicotinic receptors composed of either alpha7 or alpha4 and beta2 subunits is revealed in B lymphocytes by means of radioligand binding assay and cell ELISA. Mouse B lymphocytes contained 12,200±3200 of epibatidine-binding sites and 3130±750 of alpha-bungarotoxin-binding sites per cell," wrote M. Skok and colleagues, Palladin Institute of Biochemistry.
"Mice lacking nicotinic receptor subunits alpha4, beta2 or alpha7 had less serum IgG and IgG-producing cells in the...
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