Acetylcholine Receptors
Nicotinic receptors analyzed, regulatory roles defined
Published in Drug Week, September 9th, 2005
"The presence of nicotinic receptors composed of either alpha7 or alpha4 and beta2 subunits is revealed in B lymphocytes by means of radioligand binding assay and cell ELISA. Mouse B lymphocytes contained 12,200±3200 of epibatidine-binding sites and 3130±750 of alpha-bungarotoxin-binding sites per cell," wrote M. Skok and colleagues, Palladin Institute of Biochemistry.
"Mice lacking nicotinic receptor subunits alpha4, beta2 or alpha7 had less serum IgG and IgG-producing cells in the...
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Source: Drug Week (2005-09-09)
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